 | Up a level |
Baggio, Stéphanie; Billieux, Joël; Dirkzwager, Anja; Iglesias, Katia; Moschetti, Karine; Perroud, Nader; Schneider, Marie; Vernaz, Nathalie; Wolff, Hans; Heller, Patrick (2024). Protocol of a monocentric, double-blind, randomized, superiority, controlled trial evaluating the effect of in-prison OROS-methylphenidate vs. placebo treatment in detained people with attention-deficit hyperactivity disorder (BATIR). Trials, 25(1), p. 23. BioMed Central 10.1186/s13063-023-07827-7
Chaccour, Carlos; Casellas, Aina; Hammann, Felix; Ruiz-Castillo, Paula; Nicolas, Patricia; Montaña, Julia; Mael, Mary; Selvaraj, Prashant; Duthaler, Urs; Mrema, Sigilbert; Kakolwa, Mwaka; Lyimo, Issa; Okumu, Fredros; Marathe, Achla; Schürch, Roger; Elobolobo, Eldo; Sacoor, Charfudin; Saute, Francisco; Xia, Kang; Jones, Caroline; ... (2023). BOHEMIA: Broad One Health Endectocide-based Malaria Intervention in Africa-a phase III cluster-randomized, open-label, clinical trial to study the safety and efficacy of ivermectin mass drug administration to reduce malaria transmission in two African settings. Trials, 24(1), p. 128. BioMed Central 10.1186/s13063-023-07098-2
Reiberger, Thomas; Berzigotti, Annalisa; Trebicka, Jonel; Ertle, Judith; Gashaw, Isabella; Swallow, Ros; Tomisser, Andrea (2023). The rationale and study design of two phase II trials examining the effects of BI 685,509, a soluble guanylyl cyclase activator, on clinically significant portal hypertension in patients with compensated cirrhosis. Trials, 24(1), p. 293. BioMed Central 10.1186/s13063-023-07291-3
Fields, T; Bremova, T M; Billington, I; Churchill, G C; Evans, W; Fields, C; Galione, A; Kay, R; Mathieson, T; Martakis, K; Patterson, M; Platt, F; Factor, M; Strupp, M (2023). N-acetyl-L-leucine for Niemann-Pick type C: a multinational double-blind randomized placebo-controlled crossover study. Trials, 24(1), p. 361. BioMed Central 10.1186/s13063-023-07399-6
Naef, Rahel; Filipovic, Miodrag; Jeitziner, Marie-Madlen; von Felten, Stefanie; Safford, Judith; Riguzzi, Marco; Rufer, Michael (2022). A multicomponent family support intervention in intensive care units: study protocol for a multicenter cluster-randomized trial (FICUS Trial). Trials, 23(1), p. 533. BioMed Central 10.1186/s13063-022-06454-y
Keller, Sandra; Tschan, Franziska; Semmer, Norbert K; Trelle, Sven; Manser, Tanja; Beldi, Guido (2022). StOP? II trial: cluster randomized clinical trial to test the implementation of a toolbox for structured communication in the operating room-study protocol. Trials, 23(1), p. 878. BioMed Central 10.1186/s13063-022-06775-y
Cavelti, Marialuisa; Kaeser, Janko M; Lerch, Stefan; Bauer, Stephanie; Moessner, Markus; Berger, Thomas; Hayward, Mark; Kaess, Michael (2022). Smartphone-assisted guided self-help cognitive behavioral therapy for young people with distressing voices (SmartVoices): study protocol for a randomized controlled trial. Trials, 23(1), p. 902. BioMed Central 10.1186/s13063-022-06846-0
Reinhardt, Philipp; Giger, Roland; Seifert, Eberhard; Shelan, Mohamed; Riggenbach, Elena; Terribilini, Dario; Joosten, Andreas; Schanne, Daniel H; Aebersold, Daniel M; Manser, Peter; Dettmer, Matthias S; Simon, Christian; Ozsahin, Esat M; Moeckli, Raphaël; Limacher, Andreas; Caparrotti, Francesca; Nair, Deepa; Bourhis, Jean; Broglie, Martina A; Al-Mamgani, Abrahim; ... (2022). VoiceS: voice quality after transoral CO2 laser surgery versus single vocal cord irradiation for unilateral stage 0 and I glottic larynx cancer-a randomized phase III trial [study protocol]. Trials, 23(1), p. 906. BioMed Central 10.1186/s13063-022-06841-5
Urwyler, Pascal; Charitos, Panteleimon; Moser, Stephan; Heijnen, Ingmar A F M; Trendelenburg, Marten; Thoma, Reto; Sumer, Johannes; Camacho-Ortiz, Adrián; Bacci, Marcelo R; Huber, Lars C; Stüssi-Helbling, Melina; Albrich, Werner C; Sendi, Parham; Osthoff, Michael (2021). Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of severe SARS-CoV-2 infection in hospitalized patients with COVID-19: A structured summary of a study protocol for a randomized, parallel-group, open-label, multi-center pilot trial (PROTECT-COVID-19). Trials, 22(1), p. 1. BioMed Central 10.1186/s13063-020-04976-x
Duss, Simone B.; Brill, Anne-Kathrin; Baillieul, Sébastien; Horvath, Thomas; Zubler, Frédéric; Flügel, Dominique; Kägi, Georg; Benz, Gabriel; Bernasconi, Corrado; Ott, Sebastian R.; Korostovtseva, Lyudmila; Sviryaev, Yurii; Salih, Farid; Endres, Matthias; Tamisier, Renaud; Gouveris, Haralampos; Winter, Yaroslav; Denier, Niklaus; Wiest, Roland; Arnold, Marcel; ... (2021). Effect of early sleep apnoea treatment with adaptive servo-ventilation in acute stroke patients on cerebral lesion evolution and neurological outcomes: study protocol for a multicentre, randomized controlled, rater-blinded, clinical trial (eSATIS: early Sleep Apnoea Treatment in Stroke). Trials, 22(1), p. 83. BioMed Central 10.1186/s13063-020-04977-w
Brog, Noemi Anja; Hegy, Julia Katharina; Berger, Thomas; Znoj, Hansjörg (2021). An internet-based self-help intervention for people with psychological distress due to COVID-19: study protocol for a randomized controlled trial. Trials, 22(171), pp. 1-11. BioMed Central 10.1186/s13063-021-05089-9
Naef, Aileen C; Jeitziner, Marie-Madlen; Gerber, Stephan M.; Jenni-Moser, Béatrice; Müri, René M.; Jakob, Stephan M.; Nef, Tobias; Hänggi, Matthias (2021). Virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trial. Trials, 22(1), p. 174. BioMed Central 10.1186/s13063-021-05090-2
Fields, T; Patterson, M; Bremova-Ertl, T; Belcher, G; Billington, I; Churchill, G C; Davis, W; Evans, W; Flint, S; Galione, A; Granzer, U; Greenfield, J; Karl, R; Kay, R; Lewi, D; Mathieson, T; Meyer, T; Pangonis, D; Platt, F M; Tsang, L; ... (2021). A master protocol to investigate a novel therapy acetyl-L-leucine for three ultra-rare neurodegenerative diseases: Niemann-Pick type C, the GM2 gangliosidoses, and ataxia telangiectasia. Trials, 22(1), p. 84. BioMed Central 10.1186/s13063-020-05009-3
Kurmann, Silvia; Reber, Emilie; Vasiloglou, Maria; Schuetz, Philipp; Schoenenberger, Andreas W.; Uhlmann, Katja; Sterchi, Anna-Barbara; Stanga, Zeno (2021). Energy and protein intake in medical and geriatric inpatients with MEDPass versus conventional administration of oral nutritional supplements: study protocol for the randomized controlled MEDPass Trial. Trials, 22(1), p. 210. BioMed Central 10.1186/s13063-021-05145-4
Krebs, Jörg; Stoyanov, Jivko; Wöllner, Jens; Valido, Ezra; Pannek, Jürgen (2021). Immunomodulation for primary prevention of urinary tract infections in patients with spinal cord injury during primary rehabilitation: protocol for a randomized placebo-controlled pilot trial (UROVAXOM-pilot). Trials, 22(1), p. 677. BioMed Central 10.1186/s13063-021-05630-w
Speich, Benjamin; Chammartin, Frédérique; Smith, Daniel; Stoeckle, Marcel P; Amico, Patrizia; Eichenberger, Anna L; Hasse, Barbara; Schuurmans, Macé M; Müller, Thomas; Tamm, Michael; Dickenmann, Michael; Abela, Irene A; Trkola, Alexandra; Hirsch, Hans H; Manuel, Oriol; Cavassini, Matthias; Hemkens, Lars G; Briel, Matthias; Mueller, Nicolas J; Rauch, Andri; ... (2021). A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®. Trials, 22(1), p. 724. BioMed Central 10.1186/s13063-021-05664-0
Forth, Fiona A; Hammerle, Florian; König, Jochem; Urschitz, Michael S; Neuweiler, Philipp; Mildenberger, Eva; Kidszun, André (2021). The COPE-Trial-Communicating prognosis to parents in the neonatal ICU: Optimistic vs. PEssimistic: study protocol for a randomized controlled crossover trial using two different scripted video vignettes to explore communication preferences of parents of preterm infants. Trials, 22(1), p. 884. BioMed Central 10.1186/s13063-021-05796-3
Neukel, C.; Bermpohl, F.; Kaess, M.; Taubner, S.; Boedeker, K.; Williams, K.; Dempfle, A.; Herpertz, S. C. (2021). Understanding and breaking the intergenerational cycle of abuse in families enrolled in routine mental health services: study protocol for a randomized controlled trial and two non-interventional trials investigating mechanisms of change within the UBICA II consortium. Trials, 22(1), p. 749. BioMed Central 10.1186/s13063-021-05653-3
Cagetti, Maria Grazia; Cocco, Fabio; Calzavara, Ezio; Augello, Davide; Zangpoo, Phunchok; Campus, Guglielmo (2021). Study protocol for a randomized clinical trial to evaluate the effect of the use of Xylitol gum in the prevention of caries lesions in children living in Ladakh—the Caries Prevention Xylitol in Children (CaPreXCh) trial. Trials, 22(1), p. 871. BioMed Central 10.1186/s13063-021-05828-y
Brakenhoff, Timo B; Franks, Billy; Goodale, Brianna Mae; van de Wijgert, Janneke; Montes, Santiago; Veen, Duco; Fredslund, Eskild K; Rispens, Theo; Risch, Lorenz; Dowling, Ariel V; Folarin, Amos A; Bruijning, Patricia; Dobson, Richard; Heikamp, Tessa; Klaver, Paul; Cronin, Maureen; Grobbee, Diederick E (2021). A prospective, randomized, single-blinded, crossover trial to investigate the effect of a wearable device in addition to a daily symptom diary for the Remote Early Detection of SARS-CoV-2 infections (COVID-RED): a structured summary of a study protocol for a randomized controlled trial. Trials, 22(1), p. 694. BioMed Central 10.1186/s13063-021-05643-5
Trepp, Roman; Muri, Raphaela; Abgottspon, Stephanie; Bosanska, Lenka; Hochuli, Michel; Slotboom, Johannes; Rummel, Christian; Kreis, Roland; Everts, Regula (2020). Impact of phenylalanine on cognitive, cerebral, and neurometabolic parameters in adult patients with phenylketonuria (the PICO study): a randomized, placebo-controlled, crossover, noninferiority trial. Trials, 21(1), p. 178. BioMed Central 10.1186/s13063-019-4022-z
Trepp, Roman; Muri, Raphaela; Abgottspon, Stephanie; Bosanska, Lenka; Hochuli, Michel; Slotboom, Johannes; Rummel, Christian; Kreis, Roland; Everts, Regula (2020). Correction to: Impact of phenylalanine on cognitive, cerebral, and neurometabolic parameters in adult patients with phenylketonuria (the PICO study): a randomized, placebo-controlled, crossover, noninferiority trial. Trials, 21(1), p. 561. BioMed Central 10.1186/s13063-020-04489-7
Kasenda, Benjamin; Liu, Junhao; Jiang, Yu; Gajewski, Byron; Wu, Cen; von Elm, Erik; Schandelmaier, Stefan; Moffa, Giusi; Trelle, Sven; Schmitt, Andreas Michael; Herbrand, Amanda K; Gloy, Viktoria; Speich, Benjamin; Hopewell, Sally; Hemkens, Lars G; Sluka, Constantin; McGill, Kris; Meade, Maureen; Cook, Deborah; Lamontagne, Francois; ... (2020). Prediction of RECRUITment In randomized clinical Trials (RECRUIT-IT)-rationale and design for an international collaborative study [study protocol]. Trials, 21(1), p. 731. BioMed Central 10.1186/s13063-020-04666-8
Meier-Girard, Delphine; Ribi, Karin; Gerstenberg, Gisa; Ruhstaller, Thomas; Wolf, Ursula (2020). Eurythmy therapy versus slow movement fitness in the treatment of fatigue in metastatic breast cancer patients: study protocol for a randomized controlled trial. Trials, 21(1), p. 612. BioMed Central 10.1186/s13063-020-04542-5
Barco, Stefano; Bingisser, Roland; Colucci, Giuseppe; Frenk, André; Gerber, Bernhard; Held, Ulrike; Mach, Francois; Mazzolai, Lucia; Righini, Marc; Rosemann, Thomas; Sebastian, Tim; Spescha, Rebecca; Stortecky, Stefan; Windecker, Stephan; Kucher, Nils (2020). Enoxaparin for primary thromboprophylaxis in ambulatory patients with coronavirus disease-2019 (the OVID study): a structured summary of a study protocol for a randomized controlled trial. Trials, 21(1), p. 770. BioMed Central 10.1186/s13063-020-04678-4
Chabriat, Hugues; Bassetti, Claudio L.; Marx, Ute; Picarel-Blanchot, Françoise; Sors, Aurore; Gruget, Celine; Saba, Barbara; Wattez, Marine; Audoli, Marie-Laure; Hermann, Dirk M. (2020). Randomized Efficacy and Safety Trial with Oral S 44819 after Recent ischemic cerebral Event (RESTORE BRAIN study): a placebo controlled phase II study. Trials, 21(1), p. 136. BioMed Central 10.1186/s13063-020-4072-2
Waitz, Markus; Engel, Corinna; Schloesser, Rolf; Rochwalsky, Ulrich; Meyer, Sascha; Larsen, Alexander; Hoffmann, Paul; Zemlin, Michael; Bohnhorst, Bettina; Peter, Corinna; Hoppenz, Marc; Pabst, Thomas; Zimmer, Klaus-Peter; Franz, Axel R; Haertel, Christoph; Frieauff, Eric; Sandkötter, Julia; Masjosthusmann, Katja; Deindl, Philipp; Singer, Dominique; ... (2020). Application of two different nasal CPAP levels for the treatment of respiratory distress syndrome in preterm infants-"The OPTTIMMAL-Trial"-Optimizing PEEP To The IMMAture Lungs: study protocol of a randomized controlled trial. Trials, 21(1), p. 822. BioMed Central 10.1186/s13063-020-04660-0
Chaccour, Carlos; Ruiz-Castillo, Paula; Richardson, Mary-Ann; Moncunill, Gemma; Casellas, Aina; Carmona-Torre, Francisco; Giráldez, Miriam; Mota, Juana Schwartz; Yuste, José Ramón; Azanza, José Ramón; Fernández, Miriam; Reina, Gabriel; Dobaño, Carlota; Brew, Joe; Sadaba, Belen; Hammann, Felix; Rabinovich, Regina (2020). The SARS-CoV-2 Ivermectin Navarra-ISGlobal Trial (SAINT) to Evaluate the Potential of Ivermectin to Reduce COVID-19 Transmission in low risk, non-severe COVID-19 patients in the first 48 hours after symptoms onset: A structured summary of a study protocol for a randomized control pilot trial. Trials, 21(1), p. 498. BioMed Central 10.1186/s13063-020-04421-z
Sánchez, Alba; Thomas, Christine; Deeken, Friederike; Wagner, Sören; Klöppel, Stefan; Kentischer, Felix; von Arnim, Christine A. F.; Denkinger, Michael; Conzelmann, Lars O.; Biermann-Stallwitz, Janine; Joos, Stefanie; Sturm, Heidrun; Metz, Brigitte; Auer, Ramona; Skrobik, Yoanna; Eschweiler, Gerhard W.; Rapp, Michael A. (2019). Patient safety, cost-effectiveness, and quality of life: reduction of delirium risk and postoperative cognitive dysfunction after elective procedures in older adults—study protocol for a stepped-wedge cluster randomized trial (PAWEL Study). Trials, 20(1), p. 71. BioMed Central 10.1186/s13063-018-3148-8
Gaskell, Amy; Pullon, Rebecca; Hight, Darren; Termaat, Jonathan; Mans, Gay; Voss, Logan; Kreuzer, Matthias; Schmid, Sebastian; Kratzer, Stephan; Rodriguez, Amy; Schneider, Gerhard; Garcia, Paul; Sleigh, Jamie (2019). Modulation of frontal EEG alpha oscillations during maintenance and emergence phases of general anaesthesia to improve early neurocognitive recovery in older patients: protocol for a randomised controlled trial. Trials, 20(1), p. 146. BioMed Central 10.1186/s13063-019-3178-x
Nikolakopoulou, Adriani; Trelle, Sven; Sutton, Alex J; Egger, Matthias; Salanti, Georgia (2019). Synthesizing existing evidence to design future trials: survey of methodologists from European institutions. Trials, 20(1), p. 334. BioMed Central 10.1186/s13063-019-3449-6
Pfortmüller, Carmen; Messmer, Anna S.; Hess, Benjamin; Reineke, David; Jakob, Laura; Wenger, Stefanie; Waskowski, Jan; Zürcher, Patrick; Stöhr, Frederik; Erdös, Gabor; Luedi, Markus M.; Jakob, Stephan M.; Englberger, Lars; Schefold, Jörg C. (2019). Hypertonic saline for fluid resuscitation after cardiac surgery (HERACLES): study protocol for a preliminary randomised controlled clinical trial. Trials, 20(1), p. 357. BioMed Central 10.1186/s13063-019-3420-6
Tschümperlin, Raphaela Martina; Stein, Maria; Batschelet, Hallie Margareta; Moggi, Franz; Soravia, Leila (2019). Learning to resist the urge: a double-blind, randomized controlled trial investigating alcohol-specific inhibition training in abstinent patients with alcohol use disorder. Trials, 20(1), p. 402. BioMed Central 10.1186/s13063-019-3505-2
Kaess, Michael; Ritter, Sabrina; Lustig, Sophia; Bauer, Stephanie; Becker, Katja; Eschenbeck, Heike; Moessner, Markus; Rummel-Kluge, Christine; Salize, Hans-Joachim; Thomasius, Rainer; Resch, Franz; Koenig, Julian (2019). Promoting Help-seeking using E-technology for ADolescents with mental health problems: study protocol for a randomized controlled trial within the ProHEAD Consortium. Trials, 20(1), p. 94. BioMed Central 10.1186/s13063-018-3157-7
Kaess, Michael; Koenig, Julian; Bauer, Stephanie; Moessner, Markus; Fischer-Waldschmidt, Gloria; Mattern, Margarete; Herpertz, Sabine C.; Resch, Franz; Brown, Rebecca; In-Albon, Tina; Koelch, Michael; Plener, Paul L.; Schmahl, Christian; Edinger, Alexandra (2019). Self-injury: Treatment, Assessment, Recovery (STAR): online intervention for adolescent non-suicidal self-injury - study protocol for a randomized controlled trial. Trials, 20(1), p. 425. BioMed Central 10.1186/s13063-019-3501-6
Baldofski, Sabrina; Kohls, Elisabeth; Bauer, Stephanie; Becker, Katja; Bilic, Sally; Eschenbeck, Heike; Kaess, Michael; Moessner, Markus; Salize, Hans Joachim; Diestelkamp, Silke; Voß, Elke; Rummel-Kluge, Christine (2019). Efficacy and cost-effectiveness of two online interventions for children and adolescents at risk for depression (E.motion trial): study protocol for a randomized controlled trial within the ProHEAD consortium. Trials, 20(1), p. 53. BioMed Central 10.1186/s13063-018-3156-8
Eschenbeck, Heike; Lehner, Laya; Hofmann, Hanna; Bauer, Stephanie; Becker, Katja; Diestelkamp, Silke; Kaess, Michael; Moessner, Markus; Rummel-Kluge, Christine; Salize, Hans-Joachim (2019). School-based mental health promotion in children and adolescents with StresSOS using online or face-to-face interventions: study protocol for a randomized controlled trial within the ProHEAD Consortium. Trials, 20(1), pp. 1-12. BioMed Central 10.1186/s13063-018-3159-5
Kaess, Michael; Bauer, Stephanie (2019). Editorial Promoting Help-seeking using E-Technology for ADolescents: The ProHEAD consortium. Trials, 20(1), p. 72. BioMed Central 10.1186/s13063-018-3162-x
Diestelkamp, Silke; Wartberg, Lutz; Kaess, Michael; Bauer, Stephanie; Rummel-Kluge, Christine; Becker, Katja; Eschenbeck, Heike; Salize, Hans-Joachim; Moessner, Markus; Baldus, Christiane; Arnaud, Nicolas; Thomasius, Rainer (2019). Effectiveness of a web-based screening and brief intervention with weekly text-message-initiated individualised prompts for reducing risky alcohol use among teenagers: study protocol of a randomised controlled trial within the ProHEAD consortium. Trials, 20(1), p. 73. BioMed Central 10.1186/s13063-018-3160-z
Bauer, Stephanie; Bilić, Sally; Reetz, Christina; Ozer, Fikret; Becker, Katja; Eschenbeck, Heike; Kaess, Michael; Rummel-Kluge, Christine; Salize, Hans-Joachim; Diestelkamp, Silke; Moessner, Markus (2019). Efficacy and cost-effectiveness of Internet-based selective eating disorder prevention: study protocol for a randomized controlled trial within the ProHEAD Consortium. Trials, 20(1), p. 91. BioMed Central 10.1186/s13063-018-3161-y
Schefold, Joerg C.; Perner, Anders; Lange, Theis; Wetterslev, Jørn; Wise, Matt P; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Marker, Søren; Krag, Mette; Møller, Morten Hylander (2018). Effects of stress ulcer prophylaxis in adult ICU patients receiving renal replacement therapy (Sup-Icu RENal, SIREN): Study protocol for a pre-planned observational study. Trials, 19(1), p. 26. BioMed Central 10.1186/s13063-017-2408-3
Erdös, Gabor; Uehlinger, Dominik E; Kobel, Beatrice; Stucki, Monika Pia; Wiest, Roland; Stueber, Frank; Fankhauser, Niklaus; Jakob, Stephan; Schefold, Joerg C. (2018). Cerebral microembolism in the critically ill with acute kidney injury (COMET-AKI trial): study protocol for a randomized controlled clinical trial. Trials, 19(1), p. 189. BioMed Central 10.1186/s13063-018-2561-3
von Bonin, Dietrich; Klein, Sabine D.; Würker, Jana; Streit, Eva; Avianus, Oliver; Grah, Christian; Salomon, Jörg; Wolf, Ursula (2018). Speech-guided breathing retraining in asthma: a randomised controlled crossover trial in real-life outpatient settings. Trials, 19(1), p. 333. BioMed Central 10.1186/s13063-018-2727-z
Cioccari, Luca; Zante, Bjoern; Bloch, Andreas; Berger, David; Limacher, Andreas; Jakob, Stephan M; Takala, Jukka; Merz, Tobias M (2018). Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients - study protocol for a randomized controlled trial. Trials, 19(1), p. 362. BioMed Central 10.1186/s13063-018-2714-4
Salanti, Georgia; Nikolakopoulou, Adriani; Sutton, Alex J; Reichenbach, Stephan; Trelle, Sven; Naci, Huseyin; Egger, Matthias (2018). Planning a future randomized clinical trial based on a network of relevant past trials. Trials, 19(1), p. 365. BioMed Central 10.1186/s13063-018-2740-2
Cioccari, Luca; Zante, Bjoern; Bloch, Andreas; Berger, David; Limacher, Andreas; Jakob, Stephan M; Takala, Jukka; Merz, Tobias M (2018). Correction to: Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients - study protocol for a randomized controlled trial. [correction]. Trials, 19(1), p. 587. BioMed Central 10.1186/s13063-018-3001-0
Brodbeck, Jeannette; Berger, Thomas; Znoj, Hans Joerg (2017). An internet-based self-help intervention for older adults after marital bereavement, separation or divorce: study protocol for a randomized controlled trial. Trials, 18(21), pp. 1-8. BioMed Central 10.1186/s13063-016-1759-5
Löffel, Lukas; Kleeb, Bettina; Burkhard, Fiona C.; Wüthrich, Patrick Yves (2016). Erratum to: 'Perioperative use of crystalloids in patients undergoing open radical cystectomy: balanced Ringer's maleate versus a glucose 5 %/potassium-based balanced solution: study protocol for a randomized controlled trial'. Trials, 17(95), p. 95. BioMed Central 10.1186/s13063-016-1221-8
Kirkegaard, Hans; Rasmussen, Bodil S; de Haas, Inge; Nielsen, Jørgen Feldbæk; Ilkjær, Susanne; Kaltoft, Anne; Jeppesen, Anni Nørregaard; Grejs, Anders; Duez, Christophe Henri Valdemar; Larsen, Alf Inge; Pettilä, Ville Yrjö Olavi; Toome, Valdo; Arus, Urmet; Taccone, Fabio Silvio; Storm, Christian; Skrifvars, Markus B; Søreide, Eldar (2016). Time-differentiated target temperature management after out-of-hospital cardiac arrest: a multicentre, randomised, parallel-group, assessor-blinded clinical trial (the TTH48 trial): study protocol for a randomised controlled trial. Trials, 17(1), p. 228. BioMed Central 10.1186/s13063-016-1338-9
Pettilä, Ville Yrjö Olavi; Merz, Tobias Michael; Wilkman, Erika; Perner, Anders; Karlsson, Sari; Lange, Theis; Hästbacka, Johanna; Hjortrup, Peter Buhl; Kuitunen, Anne; Jakob, Stephan; Takala, Jukka (2016). Targeted tissue perfusion versus macrocirculation-guided standard care in patients with septic shock (TARTARE-2S): study protocol and statistical analysis plan for a randomized controlled trial. Trials, 17(384), p. 384. BioMed Central 10.1186/s13063-016-1515-x
Krag, Mette; Perner, Anders; Wetterslev, Jørn; Wise, Matt P.; Borthwick, Mark; Bendel, Stepani; Pelosi, Paolo; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Joerg C.; Møller, Morten Hylander (2016). Stress ulcer prophylaxis with a proton pump inhibitor versus placebo in critically ill patients (SUP-ICU trial): study protocol for a randomised controlled trial. Trials, 17(205), p. 205. BioMed Central 10.1186/s13063-016-1331-3
Eggmann, Sabrina; Verra, Martin L; Luder, Gere; Takala, Jukka; Jakob, Stephan (2016). Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: a study protocol for a randomised controlled trial. Trials, 17, p. 403. BioMed Central 10.1186/s13063-016-1533-8
Kleiboer, Annet; Smit, Jan; Bosmans, Judith; Ruwaard, Jeroen; Andersson, Gerhard; Topooco, Naira; Berger, Thomas; Krieger, Tobias; Botella, Cristina; Baños, Rosa; Chevreul, Karine; Araya, Ricardo; Cerga-Pashoja, Arlinda; Cieślak, Roman; Rogala, Anna; Vis, Christiaan; Draisma, Stasja; van Schaik, Anneke; Kemmeren, Lise; Ebert, David; ... (2016). European COMPARative Effectiveness research on blended Depression treatment versus treatment-as-usual (E-COMPARED): study protocol for a randomized controlled, non-inferiority trial in eight European countries. Trials, 17(1), p. 387. BioMed Central 10.1186/s13063-016-1511-1
Pandis, Nikolaos; Fleming, Padhraig S; Koletsi, Despina; Hopewell, Sally (2016). The citation of relevant systematic reviews and randomised trials in published reports of trial protocols. Trials, 17(1), p. 581. BioMed Central 10.1186/s13063-016-1713-6
Luginbuehl, Helena; Lehmann, Corinne; Baeyens, Jean-Pierre; Kuhn, Annette; Radlinger, Lorenz (2015). Involuntary reflexive pelvic floor muscle training in addition to standard training versus standard training alone for women with stress urinary incontinence: study protocol for a randomized controlled trial. Trials, 16, p. 524. BioMed Central 10.1186/s13063-015-1051-0
Jenkinson, Michael D; Javadpour, Mohsen; Haylock, Brian J; Young, Bridget; Gillard, Helen; Vinten, Jacqui; Bulbeck, Helen; Das, Kumar; Farrell, Michael; Looby, Seamus; Hickey, Helen; Preusser, Mattheus; Mallucci, Conor L; Hughes, Dyfrig; Gamble, Carrol; Weber, Damien Charles (2015). The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial. Trials, 16(519), p. 519. BioMed Central 10.1186/s13063-015-1040-3
Zeller, Thomas; Baumgartner, Iris; Scheinert, Dierk; Brodmann, Marianne; Bosiers, Marc; Micari, Antonio; Peeters, Patrick; Vermassen, Frank; Landini, Mario (2014). IN.PACT Amphirion paclitaxel eluting balloon versus standard percutaneous transluminal angioplasty for infrapopliteal revascularization of critical limb ischemia: rationale and protocol for an ongoing randomized controlled trial. Trials, 15(63), p. 63. BioMed Central 10.1186/1745-6215-15-63
Mujagic, Edin; Zwimpfer, Tibor; Marti, Walter R; Zwahlen, Marcel; Hoffmann, Henry; Kindler, Christoph; Fux, Christoph; Misteli, Heidi; Iselin, Lukas; Lugli, Andrea Kopp; Nebiker, Christian A; von Holzen, Urs; Vinzens, Fabrizio; von Strauss, Marco; Reck, Stefan; Kraljevi, Marko; Widmer, Andreas F; Oertli, Daniel; Rosenthal, Rachel and Weber, Walter P (2014). Evaluating the optimal timing of surgical antimicrobial prophylaxis: study protocol for a randomized controlled trial. Trials, 15(1), p. 188. BioMed Central 10.1186/1745-6215-15-188
Arroyo, Diego Andoni; Togni, Mario; Puricel, Serban-George; Baeriswyl, Gérard; Lehmann, Sonja; Goy, Jean-Jacques; Stauffer, Jean-Christophe; Cook, Stéphane (2014). Comparison of everolimus- and biolimus-eluting stents with everolimus-eluting bioresorbable vascular scaffold stents: study protocol of the randomized controlled EVERBIO II. Trials, 15(9), p. 9. BioMed Central 10.1186/1745-6215-15-9
Fleckenstein, Johannes; Baeumler, Petra I; Gurschler, Caroline; Weissenbacher, Tobias; Simang, Michael; Annecke, Thorsten; Geisenberger, Thomas; Irnich, Dominik (2014). Acupuncture for post anaesthetic recovery and postoperative pain: study protocol for a randomised controlled trial. Trials, 15(292), p. 292. BioMed Central 10.1186/1745-6215-15-292
Löffel, Lukas; Kleeb, Bettina; Burkhard, Fiona C.; Wüthrich, Patrick Yves (2014). Perioperative use of crystalloids in patients undergoing open radical cystectomy: balanced Ringer's maleate versus a glucose 5%/potassium-based balanced solution: study protocol for a randomized controlled trial. Trials, 15, p. 276. BioMed Central 10.1186/1745-6215-15-276
Blum, Claudine A; Nigro, Nicole; Winzeler, Bettina; Suter-Widmer, Isabelle; Schuetz, Philipp; Briel, Matthias; Bingisser, Roland; Zimmerli, Werner; Ullmer, Elke; Elsaesser, Hanno; Tarr, Philip; Wirz, Sebastian; Thomann, Robert; Hofmann, Eveline; Rodondi, Nicolas; Duplain, Hervé; Burki, Dieter; Mueller, Beat; Christ-Crain, Mirjam (2014). Corticosteroid treatment for community-acquired pneumonia--the STEP trial: study protocol for a randomized controlled trial. Trials, 15, p. 257. BioMed Central 10.1186/1745-6215-15-257
Theiler, Lorenz; Hermann, Kristina; Schoettker, Patrick; Savoldelli, Georges; Urwyler, Natalie; Kleine-Brüggeney, Maren; Arheart, Kristopher L; Greif, Robert (2013). SWIVIT--Swiss video-intubation trial evaluating video-laryngoscopes in a simulated difficult airway scenario: study protocol for a multicenter prospective randomized controlled trial in Switzerland. Trials, 14(94), p. 94. London: BioMed Central 10.1186/1745-6215-14-94
Meister, Rebecca; Princip, Mary; Schmid, Jean-Paul; Schnyder, Ulrich; Barth, Jürgen; Znoj, Hansjörg; Herbert, Claudia; von Känel, Roland (2013). Myocardial Infarction - Stress PRevention INTervention (MI-SPRINT) to reduce the incidence of posttraumatic stress after acute myocardial infarction through trauma-focused psychological counseling: study protocol for a randomized controlled trial. Trials, 14(329), p. 329. BioMed Central 10.1186/1745-6215-14-329
Sibilitz, Kirstine Laerum; Berg, Selina Kikkenborg; Hansen, Tina Birgitte; Risom, Signe Stelling; Rasmussen, Trine Bernholdt; Hassager, Christian; Køber, Lars; Steinbrüchel, Daniel; Gluud, Christian; Winkel, Per; Thygesen, Lau Caspar; Hansen, Jane Lindschou; Schmid, Jean Paul; Conraads, Viviane; Brocki, Barbara Christina; Zwisler, Ann-Dorthe (2013). Effect of comprehensive cardiac rehabilitation after heart valve surgery (CopenHeartVR): study protocol for a randomised clinical trial. Trials, 14(1), p. 104. BioMed Central 10.1186/1745-6215-14-104
Prutsky, Gabriela J.; Domecq, Juan Pablo; Erwin, Patricia J.; Briel, Matthias; Montori, Victor M.; Akl, Elie A.; Meerpohl, Joerg J.; Bassler, Dirk; Schandelmaier, Stefan; Walter, Stephen D; Zhou, Qi; Coello, Pablo Alonso; Moja, Lorenzo; Walter, Martin Alexander; Thorlund, Kristian; Glasziou, Paul; Kunz, Regina; Ferreira-Gonzalez, Ignacio; Busse, Jason; Sun, Xin; ... (2013). Initiation and continuation of randomized trials after the publication of a trial stopped early for benefit asking the same study question: STOPIT-3 study design. Trials, 14, p. 335. BioMed Central 10.1186/1745-6215-14-335
Feixas, Guillem; Bados, Arturo; Garcia-Grau, Eugeni; Montesano, Adrian; Dada, Gloria; Compan, Vicotria; Aguilera, Mari; Salla, Marta; Soldevilla, Joan Miquel; Trujillo, Adriana; Paz, Clara; Botella, Lluis; Corbella, Sergi; Saul-Gutierrez, Luis Angel; Canete, José; Gasol, Miquel; Ibarra, Montserrat; Medeiros-Ferreira, Leticia; Soriano, José; Ribeiro, Eugénia; ... (2013). Efficacy of a dilemma-focused intervention for unipolar depression: study protocol for a multicenter randomized controlled trial. Trials, 14(144), pp. 1-21. BioMed Central 10.1186/1745-6215-14-144
Messerli-Bürgy, Nadine; Barth, Jürgen; Berger, Thomas (2012). The InterHerz project--a web-based psychological treatment for cardiac patients with depression: study protocol of a randomized controlled trial. Trials, 13, p. 245. London: BioMed Central 10.1186/1745-6215-13-245
Khattab, Ahmed A; Windecker, Stephan; Jüni, Peter; Hildick-Smith, David; Dudek, Dariusz; Andersen, Henning R; Ibrahim, Reda; Schuler, Gerhard; Walton, Antony S; Wahl, Andreas; Mattle, Heinrich P; Meier, Bernhard (2011). Randomized clinical trial comparing percutaneous closure of patent foramen ovale (PFO) using the Amplatzer PFO Occluder with medical treatment in patients with cryptogenic embolism (PC-Trial): rationale and design. Trials, 12, p. 56. London: BioMed Central 10.1186/1745-6215-12-56
Knebel, P; Schwan, K; Bruckner, T; Seiler, Cm; Plaschke, K; Streitberger, K; Schaible, A; Bopp, C (2011). Double-blinded, randomized controlled trial comparing real versus placebo acupuncture to improve tolerance of diagnostic esophagogastroduodenoscopy without sedation: a study protocol. Trials, 12, p. 52. London: BioMed Central 10.1186/1745-6215-12-52
Urwyler, Natalie; Trelle, Sven; Theiler, Lorenz; Jüni, Peter; Staub, Lukas P; Luyet, Cedric; Alberio, Lorenzo; Stricker, Kay; Greif, Robert (2009). Does point of care prothrombin time measurement reduce the transfusion of fresh frozen plasma in patients undergoing major surgery? The POC-OP randomized-controlled trial. Trials, 10, p. 107. London: BioMed Central 10.1186/1745-6215-10-107
Kamm, Christian P; Mattle, Heinrich P (2009). SWiss Atorvastatin and interferon Beta-1b trial In Multiple Sclerosis (SWABIMS)--rationale, design and methodology. Trials, 10, p. 115. London: BioMed Central 10.1186/1745-6215-10-115
