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Ruffieux, Yann; Fernandez Villalobos, Nathalie Veronica; Didden, Christiane; Haas, Andreas D; Chinogurei, Chido; Cornell, Morna; Egger, Matthias; Maartens, Gary; Folb, Naomi; Rohner, Eliane (2024). Prostate cancer diagnosis rates among insured men with and without HIV in South Africa: a cohort study. Cancer epidemiology, biomarkers & prevention, 33(8), pp. 1057-1064. American Association for Cancer Research AACR 10.1158/1055-9965.EPI-24-0137
Gallon, John; Rodríguez-Calero, Antonio; Benjak, Andrej; Akhoundova, Dilara; Maletti, Sina; Amstutz, Ursula; Hewer, Ekkehard; Genitsch, Vera; Fleischmann, Achim; Rushing, Elisabeth J; Grobholz, Rainer; Fischer, Ingeborg; Jochum, Wolfram; Cathomas, Gieri; Osunkoya, Adeboye O; Bubendorf, Lukas; Moch, Holger; Thalmann, George; Feng, Felix Y; Gillessen, Silke; ... (2023). DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations. Cancer research, 83(8), pp. 1203-1213. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-22-2236
Pauli, Chantal; De Boni, Lamberto; Pauwels, Jonathan E; Chen, Yanjiang; Planas-Paz, Lara; Shaw, Reid; Emerling, Brooke M; Grandori, Carla; Hopkins, Benjamin D; Rubin, Mark A (2022). A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients. Molecular cancer research, 20(2), pp. 244-252. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-21-0255
Schatton, Tobias; Itoh, Yuta; Martins, Christina; Rasbach, Erik; Singh, Praveen; Silva, Mariana; Mucciarone, Kyla N; Heppt, Markus V; Geddes-Sweeney, Jenna; Stewart, Kate; Brandenburg, Anne; Liang, Jennifer; Dimitroff, Charles J; Mihm, Martin C; Landsberg, Jennifer; Schlapbach, Christoph; Lian, Christine G; Murphy, George F; Kupper, Thomas S; Ramsey, Matthew R; ... (2022). Inhibition of melanoma cell-intrinsic Tim-3 stimulates MAPK-dependent tumorigenesis. Cancer research, 82(20), pp. 3774-3784. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-22-0970
Adamczyk, Alexandra; Pastille, Eva; Kehrmann, Jan; Vu, Vivian P.; Geffers, Robert; Wasmer, Marie-Hélène; Kasper, Stefan; Schuler, Martin; Lange, Christian M; Muggli, Beat; Rau, Tilman T.; Klein, Diana; Hansen, Wiebke; Krebs, Philippe; Buer, Jan; Westendorf, Astrid M (2021). GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancer. Cancer research, 81(11), pp. 2970-2982. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2133
Smith, Jennifer S; Backes, Danielle M; Hudgens, Michael G; Mei, Wenwen; Chakraborty, Hrishikesh; Rohner, Eliane; Moses, Stephen; Agot, Kawango; Meijer, Chris J L M; Bailey, Robert C (2021). Male Circumcision Reduces Penile HPV Incidence and Persistence: A Randomized Controlled Trial in Kenya. Cancer epidemiology, biomarkers & prevention, 30(6), pp. 1139-1148. American Association for Cancer Research AACR 10.1158/1055-9965.EPI-20-1272
Weber, Walter Paul; Kappos, Elisabeth A; Regan, Meredith M; Moffa, Giusi; Harder, Yves; Ribi, Karin; Potter, Shelley; Pusic, Andrea; Fehr, Mathias K; Hemkens, Lars G; Holzbach, Thomas; Farhadi, Jian; Simonson, Colin; Knauer, Michael; Verstappen, Ralph; Bucher, Heiner; Zwahlen, Daniel; Zimmermann, Frank; Schwenkglenks, Matthias; Mucklow, Rosine; ... (2021). Abstract OT-23-03: Pre- versus sub-pectoral implant-based breast reconstruction after skin-sparing mastectomy or nipple-sparing mastectomy (OPBC-02 PREPEC): A pragmatic, multicenter, randomized, superiority trial. Cancer research, 71(4, Suppl.), OT-23-03-OT-23-03. American Association for Cancer Research AACR 10.1158/1538-7445.SABCS20-OT-23-03
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Kunzke, Thomas; Prade, Verena M; Buck, Achim; Sun, Na; Feuchtinger, Annette; Matzka, Marco; Fernandez, Isis E; Wuyts, Wim; Ackermann, Maximilian; Jonigk, Danny; Aichler, Michaela; Schmid, Ralph A; Eickelberg, Oliver; Berezowska, Sabina; Walch, Axel (2021). Patterns of Carbon-Bound Exogenous Compounds in Patients with Lung Cancer and Association with Disease Pathophysiology. Cancer research, 81(23), pp. 5862-5875. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-21-1175
Cotter, Kellie A; Gallon, John; Uebersax, Nadine; Rubin, Philip; Meyer, Kate D; Piscuoglio, Salvatore; Jaffrey, Samie R; Rubin, Mark A (2021). Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-Low Induction of Therapy Resistance. Molecular cancer research, 19(8), pp. 1398-1411. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-21-0014
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Nisa, Lluís; Francica, Paola; Giger, Roland; Medo, Matúš; Eliçin, Olgun; Friese-Hamim, Manja; Wilm, Claudia; Stroh, Christopher; Bojaxhiu, Beat; Quintin, Aurélie; Caversaccio, Marco D.; Dettmer, Matthias S.; Buchwalder, Mélanie; Brodie, Tess M.; Aebersold, Daniel M.; Zimmer, Yitzhak; Carey, Thomas E.; Medova, Michaela (2020). Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma. Molecular cancer therapeutics, 19(2), pp. 614-626. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-18-1274
Gleave, Martin E; Kawai, Yoshihisa; Imada, Kenjiro; Akamatsu, Shusuke; Zhang, Fan; Seiler, Roland; Hayashi, Tetsutaro; Leong, Jeffrey; Beraldi, Eliana; Saxena, Neetu; Kretschmer, Alexander; Oo, Htoo Zarni; Contreras-Sanz, Alberto; Matsuyama, Hideyasu; Lin, Dong; Fazli, Ladan; Collins, Colin C; Wyatt, Alexander W; Black, Peter C (2020). Paternally Expressed Gene 10 (PEG10) Promotes Growth, Invasion and Survival of Bladder Cancer. Molecular cancer therapeutics, 19(10), pp. 2210-2220. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-1031
Cerciello, Ferdinando; Choi, Meena; Sinicropi-Yao, Sara L; Lomeo, Katie; Amann, Joseph M; Felley-Bosco, Emanuela; Stahel, Rolf A; Robinson, Bruce W S; Creaney, Jenette; Pass, Harvey I; Vitek, Olga; Carbone, David P (2020). Verification of a Blood-Based Targeted Proteomics Signature for Malignant Pleural Mesothelioma. Cancer epidemiology, biomarkers & prevention, 29(10), pp. 1973-1982. American Association for Cancer Research AACR 10.1158/1055-9965.EPI-20-0543
Al Sayed, M; Amrein, Martin Lukas; Bührer, Emanuel; Huguenin, AL; Radpour, Ramin; Riether, Carsten; Ochsenbein, Adrian (2019). T-cell-Secreted TNFα Induces Emergency Myelopoiesis and Myeloid-Derived Suppressor Cell Differentiation in Cancer. Cancer research, 79(2), pp. 346-359. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-17-3026
Zoni, Eugenio; Astrologo, Letizia; Ng, Kiu Yan Charlotte; Piscuoglio, Salvatore; Melsen, Janine; Grosjean, Joël; Klima, Irena; Chen, Lanpeng; Snaar-Jagalska, Ewa B; Flanagan, Kenneth; van der Pluijm, Gabri; Kloen, Peter; Cecchini, Marco G; Kruithof-de Julio, Marianna; Thalmann, George (2019). Therapeutic targeting of CD146/MCAM reduces bone metastasis in prostate cancer. Molecular cancer research, 17(5), pp. 1049-1062. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-1220
Barazas, Marco; Gasparini, Alessia; Huang, Yike; Küçükosmanoğlu, Asli; Annunziato, Stefano; Bouwman, Peter; Sol, Wendy; Kersbergen, Ariena; Proost, Natalie; de Korte-Grimmerink, Renske; van de Ven, Marieke; Jonkers, Jos; Borst, Gerben R; Rottenberg, Sven (2019). Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors. Cancer research, 79(3), pp. 452-460. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-18-2077
Andres, Martin; Feller, Anita; Arndt, Volker (2018). Trends of incidence, mortality, and survival of multiple myeloma in Switzerland between 1994 and 2013. Cancer epidemiology, biomarkers & prevention, 53, pp. 105-110. American Association for Cancer Research AACR 10.1016/j.canep.2018.01.015
Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056
Pich, Christine; Meylan, Patrick; Mastelic-Gavillet, Beatris; Nguyen, Thanh Nhan; Loyon, Romain; Trang, Bao Khanh; Moser, Hélène; Moret, Catherine; Göpfert, Christine; Hafner, Jürg; Levesque, Mitchell P; Romero, Pedro; Jandus, Camilla; Michalik, Liliane (2018). Induction of Paracrine Signaling in Metastatic Melanoma Cells by PPARγ Agonist Rosiglitazone Activates Stromal Cells and Enhances Tumor Growth. Cancer research, 78(22), pp. 6447-6461. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-18-0912
Tettamanti, Giorgio; Shu, Xiaochen; Adel Fahmideh, Maral; Schüz, Joachim; Röösli, Martin; Tynes, Tore; Grotzer, Michael; Johansen, Christoffer; Klaeboe, Lars; Kuehni, Claudia E; Lannering, Birgitta; Schmidt, Lisbeth S; Vienneau, Danielle; Feychting, Maria (2017). Prenatal and Postnatal Medical Conditions and the Risk of Brain Tumors in Children and Adolescents: An International Multicenter Case-Control Study. Cancer epidemiology, biomarkers & prevention, 26(1), pp. 110-115. American Association for Cancer Research AACR 10.1158/1055-9965.EPI-16-0451
Wiedmer, Tabea; Blank, Annika; Pantasis, Sophia; Normand, Lea Elena Haaning; Bill, Ruben; Krebs, Philippe; Tschan, Mario; Marinoni, Ilaria; Perren, Aurel (2017). Autophagy inhibition improves sunitinib efficacy in pancreatic neuroendocrine tumors via a lysosome-dependent mechanism. Molecular cancer therapeutics, 16(11), pp. 2502-2515. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-17-0136
Murone, Maximilien; Radpour, Ramin; Attinger, Antoine; Chessex, Anne Vaslin; Huguenin, Anne-Laure; Schürch, Christian M; Banz Wälti, Yara; Sengupta, Saumitra; Aguet, Michel; Rigotti, Stefania; Bachhav, Yogeshwar; Massière, Frédéric; Ramachandra, Murali; McAllister, Andres; Riether, Carsten (2017). The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34+ Stem/Progenitor Cells. Molecular cancer therapeutics, 16(8), pp. 1497-1510. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-16-0889
Ruprecht, Nico; Hungerbuehler, Martin; Kellmann, Philipp; Harder, Nathalie; Schmidt, Günter; Wotzkow Alvarez, Carlos; Haenni, Beat; Blank, Fabian; von Tengg-Kobligk, Hendrik; Granzow, Christof (2017). Abstract 1889: Formation and merger of H69 and H69AR small cell lung cancer (SCLC) tumor cell clusters (TCCs) in vitro. Cancer research, 77(Suppl 13), p. 1889. American Association for Cancer Research AACR 10.1158/1538-7445.AM2017-1889
Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580
Diesch, Tamara; von der Weid, Nicolas Xavier; Szinnai, Gabor; Schaedelin, Sabine; De Geyter, Christian; Rovó, Alicia (2016). Fertility preservation in pediatric and adolescent cancer patients in Switzerland: A qualitative cross-sectional survey. Cancer epidemiology, biomarkers & prevention, 44, pp. 141-146. American Association for Cancer Research AACR 10.1016/j.canep.2016.08.013
Oplustil O'Connor, Lenka; Rulten, Stuart L; Cranston, Aaron N; Odedra, Rajesh; Brown, Henry; Jaspers, Janneke E; Jones, Louise; Knights, Charlotte; Evers, Bastiaan; Ting, Attilla; Bradbury, Robert H; Pajic, Marina; Rottenberg, Sven; Jonkers, Jos; Rudge, David; Martin, Niall M B; Caldecott, Keith W; Lau, Alan; O'Connor, Mark J (2016). The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models. Cancer research, 76(20), pp. 6084-6094. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-3240
Jaspers, Janneke E; Sol, Wendy; Kersbergen, Ariena; Schlicker, Andreas; Guyader, Charlotte; Xu, Guotai; Wessels, Lodewyk; Borst, Piet; Jonkers, Jos; Rottenberg, Sven (2015). BRCA2-Deficient Sarcomatoid Mammary Tumors Exhibit Multidrug Resistance. Cancer research, 75(4), pp. 732-741. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-14-0839
Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022
Anz, D.; Rapp, M.; Eiber, S.; Kölzer, Viktor H.; Thaler, R.; Haubner, S.; Knott, M.; Nagel, S.; Golic, M.; Wiedemann, G. M.; Bauernfeind, F.; Wurzenberger, C.; Hornung, V.; Scholz, C.; Mayr, D.; Rothenfusser, S.; Endres, S.; Bourquin, C. (2015). Suppression of Intratumoral CCL22 by Type I Interferon Inhibits Migration of Regulatory T Cells and Blocks Cancer Progression. Cancer research, 75(21), pp. 4483-4493. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-14-3499
Simon, Manuel; Stefan, Nikolas; Borsig, Lubor; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2014). Increasing the Antitumor Effect of an EpCAM-Targeting Fusion Toxin by Facile Click PEGylation. Molecular cancer therapeutics, 2(13), pp. 375-385. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0523
Castillo, Jorge J; Bower, Mark; Brühlmann, Jérémy; Novak, Urban; Furrer, Hansjakob; Tanaka, Paula Y; Besson, Caroline; Montoto, Silvia; Cwynarski, Kate; Abramson, Jeremy S; Dalia, Samir; Bibas, Michele; Connors, Joseph M; Furman, Michael; Nguyen, Minh-Ly; Cooley, Timothy P; Beltran, Brady E; Collins, Jaime A; Vose, Julie M; Xicoy, Blanca; ... (2014). Prognostic factors for advanced-stage human immunodeficiency virus-associated classical Hodgkin lymphoma treated with doxorubicin, bleomycin, vinblastine, and dacarbazine plus combined antiretroviral therapy: A multi-institutional retrospective study. Cancer research, 121(3), pp. 423-431. American Association for Cancer Research AACR 10.1002/cncr.29066
Gao, Shan; Bajrami, Ilirjana; Verrill, Clare; Kigozi, Asha; Ouaret, Djamila; Aleksic, Tamara; Asher, Ruth; Han, Cheng; Allen, Paul; Bailey, Deborah; Feller, Stephan; Kashima, Takeshi; Athanasou, Nicholas; Blay, Jean-Yves; Schmitz, Sandra; Machiels, Jean-Pascal; Upile, Nav; Jones, Terry M; Thalmann, George; Ashraf, Shazad Q; ... (2014). Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling. Cancer research, 74(20), pp. 5866-5877. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-14-0806
Kneitz, Burkhard; Krebs, Markus; Kalogirou, Charis; Schubert, Maria; Joniau, Steven; van Poppel, Hein; Lerut, Evelyne; Kneitz, Susanne; Scholz, Claus Jürgen; Ströbel, Philipp; Gessler, Manfred; Riedmiller, Hubertus; Spahn, Martin (2014). Survival in patients with high-risk prostate cancer is predicted by miR-221, which regulates proliferation, apoptosis, and invasion of prostate cancer cells by inhibiting IRF2 and SOCS3. Cancer research, 74(9), pp. 2591-2603. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-13-1606
Charles, Roch-Philippe; Silva, Jillian; Iezza, Gioia; Phillips, Wayne A; McMahon, Martin (2014). Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis. Molecular cancer research, 12(7), pp. 979-986. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-14-0158-T
Mathe, E. A.; Patterson, A. D.; Haznadar, M.; Manna, S. K.; Krausz, K. W.; Bowman, E. D.; Shields, P. G.; Idle, Jeffrey; Smith, P. B.; Anami, K.; Kazandjian, D. G.; Hatzakis, E.; Gonzalez, F. J.; Harris, C. C. (2014). Noninvasive Urinary Metabolomic Profiling Identifies Diagnostic and Prognostic Markers in Lung Cancer. Cancer research, 74(12), pp. 3259-3270. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-14-0109
Medová, Michaela; Pochon, Benoît; Streit, Bruno; Blank-Liss, Wieslawa; Francica, Paola; Stroka, Deborah; Keogh, Adrian; Aebersold, Daniel M.; Blaukat, Andree; Bladt, Friedhelm; Zimmer, Yitzhak (2013). The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants. Molecular cancer therapeutics, 12(11), pp. 2415-2424. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0151
Longoni, Nicole; Sarti, Manuela; Albino, Domenico; Civenni, Gianluca; Malek, Anastasia; Ortelli, Erica; Pinton, Sandra; Mello-Grand, Maurizia; Ostano, Paola; D'Ambrosio, Gioacchino; Sessa, Fausto; Garcia-Escudero, Ramon; Thalmann, George N.; Chiorino, Giovanna; Catapano, Carlo V.; Carbone, Giuseppina M. (2013). ETS Transcription Factor ESE1/ELF3 Orchestrates a Positive Feedback Loop That Constitutively Activates NF- B and Drives Prostate Cancer Progression. Cancer research, 73(14), pp. 4533-4547. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-12-4537
Portmann, Simone; Fahrner, René; Lechleiter, Antje; Keogh, Adrian; Overney, Sarah; Lämmle, Alexander; Mikami, Kei; Montani, Matteo; Tschan, Mario; Candinas, Daniel; Keogh-Stroka, Deborah M. (2013). Antitumor effect of SIRT1 inhibition in human HCC tumor models in vitro and in vivo. Molecular cancer therapeutics, 12(4), pp. 499-508. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-12-0700
Alitalo, Annamari K; Proulx, Steven T; Karaman, Sinem; Aebischer, David; Martino, Stefania; Jost, Manuela; Schneider, Nicole; Bry, Maija; Detmar, Michael (2013). VEGF-C and VEGF-D blockade inhibits inflammatory skin carcinogenesis. Cancer research, 73(14), pp. 4212-4221. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-12-4539
Claus, Christina; Riether, Carsten; Schürch, Christian; Matter, Matthias S; Hilmenyuk, Tamara; Ochsenbein, Adrian (2012). CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth. Cancer research, 72(14), pp. 3664-76. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-11-2791
Rabellino, A.; Carter, B.; Konstantinidou, Georgia; Wu, S.-Y.; Rimessi, A.; Byers, L. A.; Heymach, J. V.; Girard, L.; Chiang, C.-M.; Teruya-Feldstein, J.; Scaglioni, P. P. (2012). The SUMO E3-ligase PIAS1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA. Cancer research, 72(9), pp. 2275-2284. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-11-3159
Duong, Tam; Proulx, Steven T; Luciani, Paola; Leroux, Jean-Christophe; Detmar, Michael; Koopman, Peter; Francois, Mathias (2012). Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice. Cancer research, 72(12), pp. 3105-3114. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-11-4026
Piguet, Anne-Christine; Saar, Bettina; Hlushchuk, Ruslan; St-Pierre, Marie V; McSheehy, Paul M J; Radojevic, Vesna; Afthinos, Maresa; Terracciano, Luigi; Djonov, Valentin; Dufour, Jean-François (2011). Everolimus augments the effects of sorafenib in a syngeneic orthotopic model of hepatocellular carcinoma. Molecular cancer therapeutics, 10(6), pp. 1007-17. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-10-0666
Wild, Damian; Frischknecht, Michael; Zhang, Hanwen; Morgenstern, Alfred; Bruchertseifer, Frank; Boisclair, Julie; Provencher-Bolliger, Anne; Reubi, Jean-Claude; Maecke, Helmut R (2011). Alpha- versus beta-particle radiopeptide therapy in a human prostate cancer model (213Bi-DOTA-PESIN and 213Bi-AMBA versus 177Lu-DOTA-PESIN). Cancer research, 71(3), pp. 1009-18. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-10-1186
Patterson, Andrew D; Maurhofer, Olivier; Beyoglu, Diren; Lanz, Christian; Krausz, Kristopher W; Pabst, Thomas; Gonzalez, Frank J; Dufour, Jean-François; Idle, Jeffrey R (2011). Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling. Cancer research, 71(21), pp. 6590-600. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-11-0885
Guerreiro, Ana S; Fattet, Sarah; Kulesza, Dorota W; Atamer, Abdullah; Elsing, Alexandra N; Shalaby, Tarek; Jackson, Shaun P; Schoenwaelder, Simone M; Grotzer, Michael A; Delattre, Olivier; Arcaro, Alexandre (2011). A sensitized RNA interference screen identifies a novel role for the PI3K p110γ isoform in medulloblastoma cell proliferation and chemoresistance. Molecular cancer research, 9(7), pp. 925-35. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1541-7786.MCR-10-0200
Crosbie, Emma J; Zwahlen, Marcel; Kitchener, Henry C; Egger, Matthias; Renehan, Andrew G (2010). Body mass index, hormone replacement therapy, and endometrial cancer risk: a meta-analysis. Cancer epidemiology, biomarkers & prevention, 19(12), pp. 3119-3130. Baltimore, Md.: American Association for Cancer Research AACR 10.1158/1055-9965.EPI-10-0832
van den Hoogen, Christel; van der Horst, Geertje; Cheung, Henry; Buijs, Jeroen T; Lippitt, Jenny M; Guzmán-Ramírez, Natalia; Hamdy, Freddie C; Eaton, Colby L; Thalmann, George N; Cecchini, Marco G; Pelger, Rob C M; van der Pluijm, Gabri (2010). High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer. Cancer research, 70(12), pp. 5163-73. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-09-3806
Castelletti, Deborah; Fiaschetti, Giulio; Di Dato, Valeria; Ziegler, Urs; Kumps, Candy; De Preter, Katleen; Zollo, Massimo; Speleman, Frank; Shalaby, Tarek; De Martino, Daniela; Berg, Thorsten; Eggert, Angelika; Arcaro, Alexandre; Grotzer, Michael A (2010). The quassinoid derivative NBT-272 targets both the AKT and ERK signaling pathways in embryonal tumors. Molecular cancer therapeutics, 9(12), pp. 3145-57. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-10-0539
Shalaby, Tarek; von Bueren, André O; Hürlimann, Marie-Louise; Fiaschetti, Giulio; Castelletti, Deborah; Masayuki, Tera; Nagasawa, Kazuo; Arcaro, Alexandre; Jelesarov, Ilian; Shin-ya, Kazuo; Grotzer, Michael (2010). Disabling c-Myc in childhood medulloblastoma and atypical teratoid/rhabdoid tumor cells by the potent G-quadruplex interactive agent S2T1-6OTD. Molecular cancer therapeutics, 9(1), pp. 167-79. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-09-0586
Mumprecht, Viviane; Honer, Michael; Vigl, Benjamin; Proulx, Steven T; Trachsel, Eveline; Kaspar, Manuela; Banziger-Tobler, Nadja E; Schibli, Roger; Neri, Dario; Detmar, Michael (2010). In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography. Cancer research, 70(21), pp. 8842-8851. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-10-0896
Proulx, Steven T; Luciani, Paola; Derzsi, Stefanie; Rinderknecht, Matthias; Mumprecht, Viviane; Leroux, Jean-Christophe; Detmar, Michael (2010). Quantitative imaging of lymphatic function with liposomal indocyanine green. Cancer research, 70(18), pp. 7053-7062. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-10-0271
Bandi, Nora; Zbinden, Samuel; Gugger, Mathias; Arnold, Marlene; Kocher, Verena; Hasan, Lara; Kappeler, Andreas; Brunner, Thomas; Vassella, Erik (2009). miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer. Cancer research, 69(13), pp. 5553-9. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-08-4277
Winkler, Johannes; Martin-Killias, Patricia; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2009). EpCAM-targeted delivery of nanocomplexed siRNA to tumor cells with designed ankyrin repeat proteins. Molecular cancer therapeutics, 8(9), pp. 2674-83. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-09-0402
Jenal, Mathias; Trinh, Emmanuelle; Britschgi, Christian; Britschgi, Adrian; Roh, Vincent; Vorburger, Stephan A; Tobler, Andreas; Leprince, Dominique; Fey, Martin F; Helin, Kristian; Tschan, Mario P (2009). The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1. Molecular cancer research, 7(6), pp. 916-22. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1541-7786.MCR-08-0359
Bolanz, Katrin A; Kovacs, Gergely Gy; Landowski, Christopher P; Hediger, Matthias A (2009). Tamoxifen inhibits TRPV6 activity via estrogen receptor-independent pathways in TRPV6-expressing MCF-7 breast cancer cells. Molecular cancer research, 7(12), pp. 2000-10. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1541-7786.MCR-09-0188
Fister, S; Günthert, AR; Aicher, B; Paulini, KW; Emons, G; Gründker, C (2009). GnRH-II antagonists induce apoptosis in human endometrial, ovarian and breast cancer cells via activation of stress-induced MAPKs p38 and JNK and proapoptotic protein Bax. Cancer research, 69(16), pp. 6473-6481. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-08-4657
Konstantinidou, Georgia; Bey, E. A.; Rabellino, A.; Schuster, K.; Maira, M. S.; Gazdar, A. F.; Amici, A.; Boothman, D. A.; Scaglioni, P. P. (2009). Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Blockade Is an Effective Radiosensitizing Strategy for the Treatment of Non-Small Cell Lung Cancer Harboring K-RAS Mutations. Cancer research, 69(19), pp. 7644-7652. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-09-0823
Gautschi, Oliver; Tepper, Clifford G; Purnell, Phillip R; Izumiya, Yoshihiro; Evans, Christopher P; Green, Tim P; Desprez, Pierre Y; Lara, Primo N; Gandara, David R; Mack, Philip C; Kung, Hsing-Jien (2008). Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer. Cancer research, 68(7), pp. 2250-8. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-07-6403
Nesic, Dobrila; Grumont, Raelene; Gerondakis, Steve (2008). The nuclear factor-kappaB and p53 pathways function independently in primary cells and transformed fibroblasts responding to genotoxic damage. Molecular cancer research, 6(7), pp. 1193-203. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1541-7786.MCR-07-2125
Bolanz, Katrin A; Hediger, Matthias A; Landowski, Christopher P (2008). The role of TRPV6 in breast carcinogenesis. Molecular cancer therapeutics, 7(2), pp. 271-9. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-07-0478
Ganapathipillai, Suganthini S; Medová, Michaela; Aebersold, Daniel M; Manley, Paul W; Berthou, Sylvie; Streit, Bruno; Blank-Liss, Wieslawa; Greiner, Richard H; Rothen-Rutishauser, Barbara; Zimmer, Yitzhak (2008). Coupling of mutated Met variants to DNA repair via Abl and Rad51. Cancer research, 68(14), pp. 5769-77. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-08-1269
Derdak, Z; Mark, N.M.; Beldi, G; Robson, S.C.; Wands, J.R.; Baffy, G (2008). The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells. Cancer research, 68(8), pp. 2813-9. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-08-0053
Blancafort, P.; Tschan, Mario; Bergquist, S.; Guthy, D.; Brachat, A.; Sheeter, D. A.; Torbett, B. E.; Erdmann, D.; Barbas, C. F. (2008). Modulation of drug resistance by artificial transcription factors. Molecular cancer therapeutics, 7(3), pp. 688-697. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-07-0381
Matter, Matthias; Pavelic, Viktor; Pinschewer, Daniel D; Mumprecht, Sabine; Eschli, Bruno; Giroglou, Tsanan; von Laer, Dorothee; Ochsenbein, Adrian F (2007). Decreased tumor surveillance after adoptive T-cell therapy. Cancer research, 67(15), pp. 7467-76. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-06-4372
Fister, S; Günthert, AR; Emons, G; Gründker, C (2007). Gonadotropin-releasing hormone type II antagonists induce apoptotic cell death in human endometrial and ovarian cancer cells in vitro and in vivo. Cancer research, 67(4), pp. 1750-1756. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-06-3222
Hussain, Sajid; Plückthun, Andreas; Allen, Theresa M; Zangemeister-Wittke, Uwe (2007). Antitumor activity of an epithelial cell adhesion molecule targeted nanovesicular drug delivery system. Molecular cancer therapeutics, 6(11), pp. 3019-27. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-07-0615
Giorgini, Simona; Trisciuoglio, Daniela; Gabellini, Chiara; Desideri, Marianna; Castellini, Laura; Colarossi, Cristina; Zangemeister-Wittke, Uwe; Zupi, Gabriella; Del Bufalo, Donatella (2007). Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression. Molecular cancer research, 5(8), pp. 761-71. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1541-7786.MCR-07-0088
Schomber, Tibor; Kopfstein, Lucie; Djonov, Valentin; Albrecht, Imke; Baeriswyl, Vanessa; Strittmatter, Karin; Christofori, Gerhard (2007). Placental growth factor-1 attenuates vascular endothelial growth factor-A-dependent tumor angiogenesis during beta cell carcinogenesis. Cancer research, 67(22), pp. 10840-8. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472CAN-07-1034
Frese, Steffen; Frese-Schaper, Manuela; Andres, Anne-Catherine; Miescher, Daniela; Zumkehr, Beatrice; Schmid, Ralph A (2006). Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5. Cancer research, 66(11), pp. 5867-74. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-05-3544
Hussain, Sajid; Plückthun, Andreas; Allen, Theresa M; Zangemeister-Wittke, Uwe (2006). Chemosensitization of carcinoma cells using epithelial cell adhesion molecule-targeted liposomal antisense against bcl-2/bcl-xL. Molecular cancer therapeutics, 5(12), pp. 3170-80. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-06-0412