Papas, Maria G; Karatzas, Pantelis S; Papanikolaou, Ioannis S; Karamitopoulou, Evanthia; Delicha, Eumorphia M; Adler, Andreas; Triantafyllou, Konstantinos; Thomopoulou, Georgia-Heleni; Patsouris, Efstratios; Lazaris, Andreas C (2012). LFA-1 expression in a series of colorectal adenocarcinomas. Journal of gastrointestinal cancer, 43(3), pp. 462-6. New York, N.Y.: Springer 10.1007/s12029-011-9341-6
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LFA-1 is an adhesion molecule which belongs to the β2-integrin family. Overexpression of LFA-1 in hepatic natural killer cells has been associated with increased apoptosis of neoplastic cells in colorectal cancer (CRC); moreover, studies in CRC have linked LFA-1 overexpression in neoplastic cells with vascular intrusion through adhesion to endothelial cells, thus implying a possible role in creation of metastases.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology > Clinical Pathology 04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Karamitopoulou Diamantis, Evanthia |
ISSN: |
1941-6628 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:32 |
Last Modified: |
02 Mar 2023 23:21 |
Publisher DOI: |
10.1007/s12029-011-9341-6 |
PubMed ID: |
22083532 |
BORIS DOI: |
10.48350/12485 |
URI: |
https://boris.unibe.ch/id/eprint/12485 (FactScience: 218834) |
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