04 Faculty of Medicine > Service Sector > Institute of Pathology

2022

Pignatti, Emanuele; Altinkiliç, Emre Murat; Bräutigam, Konstantin; Grössl, Michael; Perren, Aurel; Zavolan, Mihaela; Flück, Christa E (2022). Cholesterol deprivation drives DHEA biosynthesis in human adrenals. Endocrinology, 163(7) Endocrine Society 10.1210/endocr/bqac076

Cyrta, Joanna; Prandi, Davide; Arora, Arshi; Hovelson, Daniel H; Sboner, Andrea; Rodriguez, Antonio; Fedrizzi, Tarcisio; Beltran, Himisha; Robinson, Dan R; Gopalan, Anurandha; True, Lawrence; Nelson, Peter S; Robinson, Brian D; Mosquera, Juan Miguel; Tomlins, Scott A; Shen, Ronglai; Demichelis, Francesca; Rubin, Mark A (2022). Comparative genomics of primary prostate cancer and paired metastases: insights from 12 molecular case studies. The journal of pathology, 257(3), pp. 274-284. Wiley 10.1002/path.5887

Karamitopoulou, Eva; Andreou, Andreas; Wenning, Anna Silvia; Gloor, Beat; Perren, Aurel (2022). High tumor mutational burden (TMB) identifies a microsatellite stable pancreatic cancer subset with prolonged survival and strong anti-tumor immunity. European journal of cancer, 169, pp. 64-73. Elsevier 10.1016/j.ejca.2022.03.033

Abbet, Christian; Studer, Linda; Fischer, Andreas; Dawson, Heather; Zlobec, Inti; Bozorgtabar, Behzad; Thiran, Jean-Philippe (2022). Self-rule to multi-adapt: Generalized multi-source feature learning using unsupervised domain adaptation for colorectal cancer tissue detection. Medical image analysis, 79(102473), p. 102473. Elsevier 10.1016/j.media.2022.102473

Ghaffari Laleh, Narmin; Muti, Hannah Sophie; Loeffler, Chiara Maria Lavinia; Echle, Amelie; Saldanha, Oliver Lester; Mahmood, Faisal; Lu, Ming Y; Trautwein, Christian; Langer, Rupert; Dislich, Bastian; Buelow, Roman D; Grabsch, Heike Irmgard; Brenner, Hermann; Chang-Claude, Jenny; Alwers, Elizabeth; Brinker, Titus J; Khader, Firas; Truhn, Daniel; Gaisa, Nadine T; Boor, Peter; ... (2022). Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology. Medical image analysis, 79, p. 102474. Elsevier 10.1016/j.media.2022.102474

Melin, Nicolas; Yarahmadov, Tural; Sanchez-Taltavull, Daniel; Birrer, Fabienne E; Brodie, Tess M; Petit, Benoît; Felser, Andrea; Nuoffer, Jean-Marc; Montani, Matteo; Vozenin, Marie-Catherine; Herrmann, Evelyn; Candinas, Daniel; Aebersold, Daniel M; Stroka, Deborah (2022). A new mouse model of radiation-induced liver disease reveals mitochondrial dysfunction as an underlying fibrotic stimulus. JHEP reports, 4(7), p. 100508. Elsevier 10.1016/j.jhepr.2022.100508

Barreto de Albuquerque, Juliana; Altenburger, Lukas M; Abe, Jun; von Werdt, Diego; Wissmann, Stefanie; Martínez Magdaleno, Jose; Francisco, David; van Geest, Geert; Ficht, Xenia; Iannacone, Matteo; Bruggmann, Remy; Mueller, Christoph; Stein, Jens V (2022). Microbial uptake in oral mucosa-draining lymph nodes leads to rapid release of cytotoxic CD8+ T cells lacking a gut-homing phenotype. Science immunology, 7(72), eabf1861. American Association for the Advancement of Science 10.1126/sciimmunol.abf1861

Depoilly, Thomas; Leroux, Raffaele; Andrade, Dafne; Nicolle, Remy; Dioguardi Burgio, Marco; Marinoni, Ilaria; Dokmak, Safi; Ruszniewski, Philippe; Hentic, Olivia; Paradis, Valérie; De Mestier, Louis; Perren, Aurel; Couvelard, Anne; Cros, Jérôme (2022). Immunophenotypic and molecular characterization of pancreatic neuroendocrine tumors producing serotonin. (In Press). Modern pathology Springer Nature 10.1038/s41379-022-01110-x

Acs, Balazs; Leung, Samuel C Y; Kidwell, Kelley M; Arun, Indu; Augulis, Renaldas; Badve, Sunil S; Bai, Yalai; Bane, Anita L; Bartlett, John M S; Bayani, Jane; Bigras, Gilbert; Blank, Annika; Buikema, Henk; Chang, Martin C; Dietz, Robin L; Dodson, Andrew; Fineberg, Susan; Focke, Cornelia M; Gao, Dongxia; Gown, Allen M; ... (2022). Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study. (In Press). Modern pathology Springer Nature 10.1038/s41379-022-01104-9

Ding, Ruiwen; Prasanna, Prateek; Corredor, Germán; Barrera, Cristian; Zens, Philipp; Lu, Cheng; Velu, Priya; Leo, Patrick; Beig, Niha; Li, Haojia; Toro, Paula; Berezowska, Sabina; Baxi, Vipul; Balli, David; Belete, Merzu; Rimm, David L; Velcheti, Vamsidhar; Schalper, Kurt; Madabhushi, Anant (2022). Image analysis reveals molecularly distinct patterns of TILs in NSCLC associated with treatment outcome. NPJ precision oncology, 6(1), p. 33. Springer Nature 10.1038/s41698-022-00277-5

Hirsiger, Stefanie; Dawson, Heather; Grobbelaar, Adriaan Ockert; Vögelin, Esther (2022). Atypical Pleomorphic Lipomatous Tumor of the Right Hand Mimicing Venous Malformation. Journal of hand surgery - American volume, 47(6), 587.e1-587.e5. Elsevier 10.1016/j.jhsa.2021.04.015

Bombaci, Giuseppe; Sarangdhar, Mayuresh Anant; Andina, Nicola; Tardivel, Aubry; Yu, Eric Chi-Wang; Mackie, Gillian M; Pugh, Matthew; Ozan, Vedat Burak; Banz, Yara; Spinetti, Thibaud; Hirzel, Cedric; Youd, Esther; Schefold, Joerg C; Taylor, Graham; Gazdhar, Amiq; Bonadies, Nicolas; Angelillo-Scherrer, Anne; Schneider, Pascal; Maslowski, Kendle M and Allam, Ramanjaneyulu (2022). LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity. Life science alliance, 5(6) EMBO Press 10.26508/lsa.202101226

Shen, Jian; Sun, Na; Zens, Philipp; Kunzke, Thomas; Buck, Achim; Prade, Verena M; Wang, Jun; Wang, Qian; Hu, Ronggui; Feuchtinger, Annette; Berezowska, Sabina Anna; Walch, Axel (2022). Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients. Cancer communications, 42(6), pp. 517-535. Wiley 10.1002/cac2.12310

Kremenovic, Mirela; Chan, Alfred A; Feng, Bing; Bäriswyl, Lukas; Robatel, Steve; Gruber, Thomas; Tang, Li; Lee, Delphine J; Schenk, Mirjam (2022). BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma. Journal for immunotherapy of cancer, 10(6) BioMed Central 10.1136/jitc-2021-004133

Janowczyk, Andrew; Baumhoer, Daniel; Dirnhofer, Stefan; Grobholz, Rainer; Kipar, Anja; de Leval, Laurence; Merkler, Doron; Michielin, Olivier; Moch, Holger; Perren, Aurel; Rottenberg, Sven; Rubbia-Brandt, Laura; Rubin, Mark A; Sempoux, Christine; Tolnay, Markus; Zlobec, Inti; Koelzer, Viktor Hendrik (2022). Towards a national strategy for digital pathology in Switzerland. (In Press). Virchows Archiv Springer 10.1007/s00428-022-03345-0

Rentsch, Vera; Seipel, Katja; Banz, Yara; Wiedemann, Gertrud; Porret, Naomi; Bacher, Ulrike; Pabst, Thomas (2022). Glofitamab Treatment in Relapsed or Refractory DLBCL after CAR T-Cell Therapy. Cancers, 14(10) MDPI AG 10.3390/cancers14102516

Merola, E; Pascher, A; Rinke, A; Bartsch, D K; Zerbi, A; Nappo, G; Carnaghi, C; Ciola, M; McNamara, M G; Zandee, W; Bertani, E; Marcucci, S; Modica, R; Grützmann, R; Fazio, N; de Herder, W; Valle, J W; Gress, T M; Fave, G Delle; de Pretis, G; ... (2022). Radical Resection in Entero-Pancreatic Neuroendocrine Tumors: Recurrence-Free Survival Rate and Definition of a Risk Score for Recurrence. (In Press). Annals of surgical oncology Springer 10.1245/s10434-022-11837-1

Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w

Young, Reuben S E; Bowman, Andrew P; Tousignant, Kaylyn D; Poad, Berwyck L J; Gunter, Jennifer H; Philp, Lisa K; Nelson, Colleen C; Ellis, Shane R; Heeren, Ron M A; Sadowski, Martin C; Blanksby, Stephen J (2022). Isomeric lipid signatures reveal compartmentalized fatty acid metabolism in cancer. (In Press). Journal of lipid research, 63(6), p. 100223. American Society for Biochemistry and Molecular Biology ASBMB 10.1016/j.jlr.2022.100223

Rodriguez-Calero, Antonio; Gallon, John; Akhoundova, Dilara; Maletti, Sina; Ferguson, Alison; Cyrta, Joanna; Amstutz, Ursula; Garofoli, Andrea; Paradiso, Viola; Tomlins, Scott A; Hewer, Ekkehard; Genitsch, Vera; Fleischmann, Achim; Vassella, Erik; Rushing, Elisabeth J; Grobholz, Rainer; Fischer, Ingeborg; Jochum, Wolfram; Cathomas, Gieri; Osunkoya, Adeboye O; ... (2022). Alterations in homologous recombination repair genes in prostate cancer brain metastases. Nature Communications, 13(1), p. 2400. Springer Nature 10.1038/s41467-022-30003-5

Marinoni, Ilaria (2022). Prognostic value of DAXX/ATRX loss of expression and ALT activation in PanNETs: is it time for clinical implementation? Gut, 71(5), pp. 847-848. BMJ Publishing Group 10.1136/gutjnl-2021-324664

Siegenthaler, F; Lindemann, K; Epstein, E; Rau, T T; Nastic, D; Ghaderi, M; Rydberg, F; Mueller, M D; Carlson, J; Imboden, S (2022). Time to first recurrence, pattern of recurrence, and survival after recurrence in endometrial cancer according to the molecular classification. Gynecologic oncology, 165(2), pp. 230-238. Elsevier 10.1016/j.ygyno.2022.02.024

Vollnberg, Bernd; Alberts, Ian; Genitsch, Vera; Rominger, Axel; Afshar-Oromieh, Ali (2022). Assessment of malignancy and PSMA expression of uncertain bone foci in [18F]PSMA-1007 PET/CT for prostate cancer-a single-centre experience of PET-guided biopsies. (In Press). European journal of nuclear medicine and molecular imaging Springer-Verlag 10.1007/s00259-022-05745-5

Ten Hoorn, Sanne; Waasdorp, Cynthia; van Oijen, Martijn G H; Damhofer, Helene; Trinh, Anne; Zhao, Lan; Smits, Lisanne J H; Bootsma, Sanne; van Pelt, Gabi W; Mesker, Wilma E; Mol, Linda; Goey, Kaitlyn K H; Koopman, Miriam; Medema, Jan Paul; Tuynman, Jurriaan B; Zlobec, Inti; Punt, Cornelis J A; Vermeulen, Louis; Bijlsma, Maarten F (2022). Serum-based measurements of stromal activation through ADAM12 associate with poor prognosis in colorectal cancer. BMC cancer, 22(1), p. 394. BioMed Central 10.1186/s12885-022-09436-0

Engelhardt, S; Dislich, B; Zubler, C; Maragkou, T; Wartenberg, M; Tzankov, A (2022). [Myositis as a post-acute sequela of COVID-19 disease? : Even in times of the pandemic, muscle biopsies can only be assessed in the context of accurate clinical information]. (In Press). Der Pathologe Springer 10.1007/s00292-022-01063-7

Mathys, Anina; Bacher, Ulrike; Banz, Yara; Legros, Myriam; Mansouri Taleghani, Behrouz; Novak, Urban; Pabst, Thomas (2022). Outcome of patients with mantle cell lymphoma after autologous stem cell transplantation in the pre-CAR T-cell era Letter. Hematological oncology, 40(2), pp. 292-296. Wiley 10.1002/hon.2952

Echle, A; Ghaffari Laleh, N; Quirke, P; Grabsch, H I; Muti, H S; Saldanha, O L; Brockmoeller, S F; van den Brandt, P A; Hutchins, G G A; Richman, S D; Horisberger, K; Galata, C; Ebert, M P; Eckardt, M; Boutros, M; Horst, D; Reissfelder, C; Alwers, E; Brinker, T J; Langer, R; ... (2022). Artificial intelligence for detection of microsatellite instability in colorectal cancer-a multicentric analysis of a pre-screening tool for clinical application. ESMO open, 7(2), p. 100400. BMJ 10.1016/j.esmoop.2022.100400

Dislich, Bastian; Mertz, Kirsten D; Gloor, Beat; Langer, Rupert (2022). Interspatial Distribution of Tumor and Immune Cells in Correlation with PD-L1 in Molecular Subtypes of Gastric Cancers. Cancers, 14(7) MDPI AG 10.3390/cancers14071736

Karamitopoulou, Eva (2022). Molecular Pathology of Pancreatic Cancer. Cancers, 14(6) MDPI AG 10.3390/cancers14061523

Haasnoot, Maria L; Mookhoek, Aart; Duijvestein, Marjolijn; D'Haens, Geert R A M; Bredenoord, Albert J (2022). Prognostic Value of Colonic Tissue and Blood Eosinophils in Ulcerative Colitis. (In Press). Inflammatory bowel diseases Lippincott Williams & Wilkins 10.1093/ibd/izac044

Loughrey, Maurice B.; Webster, Fleur; Arends, Mark J.; Brown, Ian; Burgart, Lawrence J.; Cunningham, Chris; Flejou, Jean-Francois; Kakar, Sanjay; Kirsch, Richard; Kojima, Motohiro; Lugli, Alessandro; Rosty, Christophe; Sheahan, Kieran; West, Nicholas P.; Wilson, Richard H.; Nagtegaal, Iris D. (2022). Dataset for Pathology Reporting of Colorectal Cancer: Recommendations from the International Collaboration on Cancer Reporting (ICCR). Annals of surgery, 275(3), e549-e561. Wolters Kluwer 10.1097/SLA.0000000000005051

Simon, Tincy; Riemer, Pamela; Jarosch, Armin; Detjen, Katharina; Di Domenico, Annunziata; Bormann, Felix; Menne, Andrea; Khouja, Slim; Monjé, Nanna; Childs, Liam H; Lenze, Dido; Leser, Ulf; Rossner, Florian; Morkel, Markus; Blüthgen, Nils; Pavel, Marianne; Horst, David; Capper, David; Marinoni, Ilaria; Perren, Aurel; ... (2022). DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors. Genome medicine, 14(1), p. 24. BioMed Central 10.1186/s13073-022-01018-w

Erickson, Lori A; Mete, Ozgur; Juhlin, C Christofer; Perren, Aurel; Gill, Anthony J (2022). Overview of 2022 WHO Classification of Parathyroid Tumors. Endocrine pathology, 33(1), pp. 64-89. Springer 10.1007/s12022-022-09709-1

van Velthuysen, Marie-Louise F; Couvelard, Anne; Rindi, Guido; Fazio, Nicola; Hörsch, Dieter; Nieveen van Dijkum, Els J; Klöppel, Günter; Perren, Aurel (2022). ENETS standardized (synoptic) reporting for neuroendocrine tumour pathology. Journal of neuroendocrinology, 34(3), e13100. Wiley-Blackwell 10.1111/jne.13100

Nosé, Vania; Gill, Anthony; Teijeiro, José Manuel Cameselle; Perren, Aurel; Erickson, Lori (2022). Overview of the 2022 WHO Classification of Familial Endocrine Tumor Syndromes. Endocrine pathology, 33(1), pp. 197-227. Springer 10.1007/s12022-022-09705-5

Lipkova, Jana; Chen, Tiffany Y; Lu, Ming Y; Chen, Richard J; Shady, Maha; Williams, Mane; Wang, Jingwen; Noor, Zahra; Mitchell, Richard N; Turan, Mehmet; Coskun, Gulfize; Yilmaz, Funda; Demir, Derya; Nart, Deniz; Basak, Kayhan; Turhan, Nesrin; Ozkara, Selvinaz; Banz, Yara; Odening, Katja E and Mahmood, Faisal (2022). Deep learning-enabled assessment of cardiac allograft rejection from endomyocardial biopsies. Nature medicine, 28(3), pp. 575-582. Springer Nature 10.1038/s41591-022-01709-2

Gulz, Marietta; Imboden, Sara; Nirgianakis, Konstantinos; Siegenthaler, Franziska; Rau, Tilman T.; Mueller, Michael D. (2022). Endometriosis and Isthmocele: Common or Rare? Journal of clinical medicine, 11(5) MDPI 10.3390/jcm11051158

Robatel, Steve; Schenk, Mirjam (2022). Current Limitations and Novel Perspectives in Pancreatic Cancer Treatment. Cancers, 14(4) MDPI AG 10.3390/cancers14040985

Carrasco-Garcia, Estefania; Lopez, Lidia; Moncho-Amor, Veronica; Carazo, Fernando; Aldaz, Paula; Collado, Manuel; Bell, Donald; Gaafar, Ayman; Karamitopoulou, Eva; Tzankov, Alexandar; Hidalgo, Manuel; Rubio, Ángel; Serrano, Manuel; Lawrie, Charles H; Lovell-Badge, Robin; Matheu, Ander (2022). SOX9 Triggers Different Epithelial to Mesenchymal Transition States to Promote Pancreatic Cancer Progression. Cancers, 14(4) MDPI AG 10.3390/cancers14040916

Müller, Felix; Lugli, Alessandro; Dawson, Heather (2022). Tumor budding in colorectal cancer—Information for clinical use and instructions for practical evaluation. Pathologe, 43(1), pp. 45-50. Springer-Medizin-Verlag 10.1007/s00292-021-01016-6

Nguyen, Huu-Giao; Lundström, Oxana; Blank, Annika; Dawson, Heather; Lugli, Alessandro; Anisimova, Maria; Zlobec, Inti (2022). Image-based assessment of extracellular mucin-to-tumor area predicts consensus molecular subtypes (CMS) in colorectal cancer. Modern pathology, 35(2), pp. 240-248. Springer Nature 10.1038/s41379-021-00894-8

Buck, Achim; Prade, Verena M; Kunzke, Thomas; Feuchtinger, Annette; Kröll, Dino; Feith, Marcus; Dislich, Bastian; Balluff, Benjamin; Langer, Rupert; Walch, Axel (2022). Metabolic tumor constitution is superior to tumor regression grading for evaluating response to neoadjuvant therapy of esophageal adenocarcinoma patients. The journal of pathology, 256(2), pp. 202-213. Wiley 10.1002/path.5828

Bräutigam, Konstantin; Christe, Lucine; Banz, Yara (2022). Value of an Action Cam in Surgical Pathology. Medical science educator, 32(1), pp. 43-46. Springer 10.1007/s40670-021-01480-y

Shumilov, Evgenii; Mazzeo, Paolo; Zinkernagel, Martin S.; Legros, Myriam; Porret, Naomi; Romagna, Lorenz; Haase, Detlef; Lenz, Georg; Novak, Urban; Banz, Yara; Pabst, Thomas; Bacher, Vera (2022). Comprehensive Laboratory Diagnostic Workup for Patients with Suspected Intraocular Lymphoma including Flow Cytometry, Molecular Genetics and Cytopathology. Current oncology, 29(2), pp. 766-776. MDPI 10.3390/curroncol29020065

Bräutigam, Konstantin; Reinhard, Stefan; Galván, José A.; Wartenberg, Martin; Hewer, Ekkehard; Schürch, Christian M. (2022). Systematic Investigation of SARS-CoV-2 Receptor Protein Distribution along Viral Entry Routes in Humans. Respiration, 101(6), pp. 610-618. Karger 10.1159/000521317

Mendoza, Yuly P.; G. Rodrigues, Susana; Delgado, Maria G.; Murgia, Giuseppe; Lange, Naomi F.; Schropp, Jonas; Montani, Matteo; Dufour, Jean-François; Berzigotti, Annalisa (2022). Inflammatory activity affects the accuracy of liver stiffness measurement by transient elastography but not by two-dimensional shear wave elastography in non-alcoholic fatty liver disease. Liver international, 42(1), pp. 102-111. Wiley 10.1111/liv.15116

Gianni’, Maurizio; Goracci, Laura; Schlaefli, Anna; Di Veroli, Alessandra; Kurosaki, Mami; Guarrera, Luca; Bolis, Marco; Foglia, Marika; Lupi, Monica; Tschan, Mario; Cruciani, Gabriele; Terao, Mineko; Garattini, Enrico (2022). Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia. Cell death & disease, 13(1), p. 30. Nature Publishing Group 10.1038/s41419-021-04476-z

Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466

2021

Zindel, Joel; Mittner, Jonas; Bayer, Julia; April-Monn, Simon L.; Kohler, Andreas; Nusse, Ysbrand; Dosch, Michel; Büchi, Isabel; Sanchez-Taltavull, Daniel; Dawson, Heather; Gomez de Agüero, Mercedes; Asahina, Kinji; Kubes, Paul; Macpherson, Andrew J.; Stroka, Deborah; Candinas, Daniel (2021). Intraperitoneal microbial contamination drives post-surgical peritoneal adhesions by mesothelial EGFR-signaling. Nature Communications, 12(1), p. 7316. Springer Nature 10.1038/s41467-021-27612-x

Kunzke, Thomas; Prade, Verena M; Buck, Achim; Sun, Na; Feuchtinger, Annette; Matzka, Marco; Fernandez, Isis E; Wuyts, Wim; Ackermann, Maximilian; Jonigk, Danny; Aichler, Michaela; Schmid, Ralph A; Eickelberg, Oliver; Berezowska, Sabina; Walch, Axel (2021). Patterns of Carbon-Bound Exogenous Compounds in Patients with Lung Cancer and Association with Disease Pathophysiology. Cancer research, 81(23), pp. 5862-5875. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-21-1175

Zlobec, Inti; Bächli, Melanie; Galuppini, Francesca; Berger, Martin D.; Dawson, Heather E.; Nagtegaal, Iris D; Lugli, Alessandro (2021). Refining the ITBCC tumor budding scoring system with a "zero-budding" category in colorectal cancer. Virchows Archiv, 479(6), pp. 1085-1090. Springer 10.1007/s00428-021-03090-w

Messmer, Anna S; Que, Yok-Ai; Schankin, Christoph; Banz, Yara; Bacher, Ulrike; Novak, Urban; Pabst, Thomas (2021). CAR T-cell therapy and critical care : A survival guide for medical emergency teams. Wiener klinische Wochenschrift, 133(23-24), pp. 1318-1325. Springer-Verlag 10.1007/s00508-021-01948-2

Hoffmann, Michèle; Schardt, Julian; Ionescu, Codruta; Wolf-Schnurrbusch, Ute E.; Wagner, Franca; Dettmer, Matthias S.; Olariu, Radu; Özdemir, Berna C. (2021). Long lasting response to anti-PD-1 therapy of recurrent conjunctival squamous cell carcinoma - A case report and systematic review of the literature. Current problems in cancer: case reports, 4, p. 100088. Elsevier 10.1016/j.cpccr.2021.100088

Karamitopoulou, Eva; Andreou, Andreas; Pahud de Mortanges, Aurélie; Tinguely, Marianne; Gloor, Beat; Perren, Aurel (2021). PD-1/PD-L1-Associated Immunoarchitectural Patterns Stratify Pancreatic Cancer Patients into Prognostic/Predictive Subgroups. Cancer immunology research, 9(12), pp. 1439-1450. American Association for Cancer Research 10.1158/2326-6066.CIR-21-0144

Laemmle, Alexander; Poms, Martin; Hsu, Bernadette; Borsuk, Mariia; Rüfenacht, Véronique; Robinson, Joshua; Sadowski, Martin C.; Nuoffer, Jean-Marc; Häberle, Johannes; Willenbring, Holger (2021). Aquaporin 9 Induction in Human iPSC-derived Hepatocytes Facilitates Modeling of Ornithine Transcarbamylase Deficiency. (In Press). Hepatology Wiley 10.1002/hep.32247

Vassella, Erik; Kashani, Elham; Zens, Philipp; Kündig, Alexandra; Fung, Christian; Scherz, Amina; Herrmann, Evelyn; Ermis, Ekin; Schmid, Ralph A.; Berezowska, Sabina (2021). Mutational profiles of primary pulmonary adenocarcinoma and paired brain metastases disclose the importance of KRAS mutations. European journal of cancer, 159, pp. 227-236. Elsevier 10.1016/j.ejca.2021.10.006

Venizelos, Andreas; Elvebakken, Hege; Perren, Aurel; Nikolaienko, Oleksii; Deng, Wei; Lothe, Inger Marie B; Couvelard, Anne; Hjortland, Geir Olav; Sundlöv, Anna; Svensson, Johanna; Garresori, Harrish; Kersten, Christian; Hofsli, Eva; Detlefsen, Sönke; Krogh, Merete; Sorbye, Halfdan; Knappskog, Stian (2021). The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms. Endocrine-related cancer, 29(1), pp. 1-14. BioScientifica Ltd. 10.1530/ERC-21-0152

Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664

Seitz, Luca; Wagner, Franca; Christ, Lisa; Banz, Yara; Villiger, Peter; Kollert, Florian Kim (2021). No blood for dark-blood: false-negative MRI in a patient with giant cell arteritis and occluded left temporal artery. Rheumatology, 60(4), pp. 2025-2026. Oxford University Press 10.1093/rheumatology/keaa386

Losmanová, Tereza; Zens, Philipp; Scherz, Amina; Schmid, Ralph; Tschan, Mario P.; Berezowska, Sabina Anna (2021). Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Advanced Non-Small Cell Lung Cancer after Neoadjuvant Therapy. Cells, 10(10) MDPI 10.3390/cells10102731

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Cardoso Alves, Ludmila; Corazza, Nadia; Micheau, Olivier; Krebs, Philippe (2021). The multifaceted role of TRAIL signaling in cancer and immunity. The FEBS journal, 288(19), pp. 5530-5554. FEBS Press 10.1111/febs.15637

Rafiq, Sreoshee; McKenna, Sharon L; Muller, Sylviane; Tschan, Mario; Humbert, Magali (2021). Lysosomes in acute myeloid leukemia: potential therapeutic targets? Leukemia, 35(10), pp. 2759-2770. Springer Nature 10.1038/s41375-021-01388-x

Messmer, Anna Sarah; Que, Yok-Ai; Schankin, Christoph; Banz, Yara; Bacher, Ulrike; Novak, Urban; Pabst, Thomas (2021). Novel Adaptive T-Cell Oncological Treatments Lead to New Challenges for Medical Emergency Teams: A 2-Year Experience From a Tertiary-Care Hospital in Switzerland. Critical care explorations, 3(10), e0552. Wolters Kluwer Health 10.1097/CCE.0000000000000552

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Moullet, Barbara; Kolev, Mirjam; Ebner, Lukas; Langer, Rupert; Gräni, Christoph; Obmann, Verena; Maurer, Martin; Semmo, Nasser; Christe, Andreas; Huber, Adrian Thomas (2021). Adult form of Langerhans cell histiocytosis with pulmonary and hepatic Involvement mimicking malignancy in a patient with chronic hepatitis C infection. Radiology case reports, 16(2), pp. 327-333. Elsevier 10.1016/j.radcr.2020.11.022

Elvebakken, Hege; Perren, A.; Scoazec, Jean-Yves; Tang, Laura H; Federspiel, Birgitte; Klimstra, David S; Vestermark, Lene W; Ali, Abir S; Zlobec, I.; Myklebust, Tor Å; Hjortland, Geir O; Langer, Seppo W; Gronbæk, Henning; Knigge, Ulrich; Tiensuu Janson, Eva; Sorbye, Halfdan (2021). A consensus developed morphological re-evaluation of 196 high-grade gastroenteropancreatic neuroendocrine neoplasms and its clinical correlations. Neuroendocrinology, 111(9), pp. 883-894. Karger 10.1159/000511905

Niederle, Bruno; Selberherr, Andreas; Bartsch, Detlef; Brandi, Maria Luisa; Doherty, Gerard M; Falconi, Massimo; Goudet, Pierre; Halfdanarson, Thorvardur R; Ito, Tetsuhide; Jensen, Robert T; Larghi, Alberto; Lee, Lingaku; Oberg, Kjell; Pavel, Marianne; Perren, Aurel; Sadowski, Samira M; Tonelli, Francesco; Triponez, Frederic; Valk, Gerlof D; O'Toole, Dermot; ... (2021). Multiple Endocrine Neoplasia Type 1 (MEN1) and the Pancreas - Diagnosis and Treatment of Functioning and Non-Functioning Pancreatic and Duodenal Neuroendocrine Neoplasia within the MEN1 Syndrome - An International Consensus Statement. Neuroendocrinology, 111(7), pp. 609-630. Karger 10.1159/000511791

Ruzgys, Paulius; Böhringer, Stephan; Dokumaci, Ayse Sila; Hari, Yvonne; Schürch, Christian M; Brühl, Frido; Schürch, Stefan; Szidat, Sönke; Riether, Carsten; Šatkauskas, Saulius; Geiser, Thomas; Hradetzky, David; Gazdhar, Amiq (2021). Electrospray Mediated Localized and Targeted Chemotherapy in a Mouse Model of Lung Cancer. Frontiers in Pharmacology, 12, p. 643492. Frontiers 10.3389/fphar.2021.643492

Berezowska, Sabina; Schmid, Andreas; Losmanová, Tereza; Trippel, Mafalda; Blank, Annika; Banz, Yara; Jakob, Stephan M.; Langer, Rupert (2021). Frequency and Significance of Pathologic Pulmonary Findings in Postmortem Examinations—A Single Center Experience before COVID-19. Diagnostics, 11(5) MDPI 10.3390/diagnostics11050894

Burren, Sandra; Reche, Katharina; Blank, Annika; Galván, José A.; Dawson, Heather; Berger, Martin D.; Zlobec, Inti; Lugli, Alessandro (2021). RHAMM in liver metastases of stage IV colorectal cancer with mismatch-repair proficient status correlates with tumor budding, cytotoxic T-cells and PD-1/PD-L1. Pathology, research and practice, 223, p. 153486. Elsevier 10.1016/j.prp.2021.153486

Ma, Lijuan; Andrieu, Thomas; Mc Kinnon, Brett; Duempelmann, Lea; Peng, Ren-Wang; Wotzkow, Carlos; Müller, Christoph; Mueller, Michael D. (2021). Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions. Journal of steroid biochemistry and molecular biology, 212, p. 105943. Elsevier 10.1016/j.jsbmb.2021.105943

Tokarchuk, Igor; Janser, Félice A.; Schläfli, Anna M.; Pinto, Marta Teixeira; Humbert, Magali; Niklaus, Nicolas J.; Berezowska, Sabina; Langer, Rupert; Tschan, Mario P. (2021). Increased LAMP2A levels correlate with a shorter disease-free survival of HER2 negative breast cancer patients and increased breast cancer cell viability. Biochemical and biophysical research communications, 569, pp. 47-53. Elsevier 10.1016/j.bbrc.2021.06.082

Rhyner Agocs, Gaëlle; Assarzadegan, Naziheh; Kirsch, Richard; Dawson, Heather; Galván, José A.; Lugli, Alessandro; Zlobec, Inti; Berger, Martin D. (2021). LAG-3 Expression Predicts Outcome in Stage II Colon Cancer. Journal of personalized medicine, 11(8) MDPI 10.3390/jpm11080749

Lang-Schwarz, Corinna; Angeloni, Miriam; Agaimy, Abbas; Atreya, Raja; Becker, Christoph; Dregelies, Theresa; Danese, Silvio; Fléjou, Jean-François; Gaßler, Nikolaus; Grabsch, Heike I; Hartmann, Arndt; Kamarádová, Kateřina; Kühl, Anja A; Lauwers, Gregory Y; Lugli, Alessandro; Nagtegaal, Iris; Neurath, Markus F; Oberhuber, Georg; Peyrin-Biroulet, Laurent; Rath, Timo; ... (2021). Validation of the ‘Inflammatory Bowel Disease—Distribution, Chronicity, Activity [IBD-DCA] Score’ for Ulcerative Colitis and Crohn´s Disease. Journal of Crohn's & colitis, 15(10), pp. 1621-1630. Oxford University Press 10.1093/ecco-jcc/jjab055

Lugli, Alessandro; Carneiro, Fatima; Dawson, Heather; Fléjou, Jean-François; Kirsch, Richard; van der Post, Rachel S.; Vieth, Michael; Svrcek, Magali (2021). The gastric disease of Napoleon Bonaparte: brief report for the bicentenary of Napoleon’s death on St. Helena in 1821. Virchows Archiv, 479(5), pp. 1055-1060. Springer 10.1007/s00428-021-03061-1

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Graf, Johannes R.; Forster, Stefan; Bruehl, Frido K.; Banz, Yara; Hallal, Mahmoud; Brodard, Justine; Bacher, Vera Ulrike; Allam, Ramanjaneyulu; Schürch, Christian M.; Bonadies, Nicolas (2021). Diagnostic and Prognostic Implications of Caspase-1 and PD-L1 Co-Expression Patterns in Myelodysplastic Syndromes. Cancers, 13(22), p. 5712. MDPI AG 10.3390/cancers13225712

Young, Reuben S E; Claes, Britt S R; Bowman, Andrew P; Williams, Elizabeth D; Shepherd, Benjamin; Perren, Aurel; Poad, Berwyck L J; Ellis, Shane R; Heeren, Ron M A; Sadowski, Martin C.; Blanksby, Stephen J (2021). Isomer-Resolved Imaging of Prostate Cancer Tissues Reveals Specific Lipid Unsaturation Profiles Associated With Lymphocytes and Abnormal Prostate Epithelia. Frontiers in endocrinology, 12, p. 689600. Frontiers Research Foundation 10.3389/fendo.2021.689600

Delgado, Maria Gabriela; Casu, Stefania; Montani, Matteo; Brunner, Felix; Semmo, Nasser; Berzigotti, Annalisa; Dufour, Jean-François (2021). Hepatic manifestations of drug reaction with eosinophilia and systemic symptoms syndrome. Exploration of medicine, 2, pp. 122-134. Open Exploration Publishing 10.37349/emed.2021.00037

Storni, Federico; Trepp, Roman; Perren, Aurel; Kollár, Attila; Gloor, Beat; Kim-Fuchs, Corina (2021). [Neuroendocrine tumor of the pancreas: What is new?]. Therapeutische Umschau, 78(10), pp. 615-621. Hogrefe 10.1024/0040-5930/a001318

Nydegger, Anna; Novak, Urban; Kronig, Marie-Noëlle; Legros, Myriam; Zeerleder, Sacha; Banz, Yara; Bacher, Ulrike; Pabst, Thomas (2021). Transformed Lymphoma Is Associated with a Favorable Response to CAR-T-Cell Treatment in DLBCL Patients. Cancers, 13(23) MDPI AG 10.3390/cancers13236073

Eyer, Gian-Carlo; Di Santo, Stefano; Hewer, Ekkehard; Andereggen, Lukas; Seiler, Stefanie; Widmer, Hans Rudolf (2021). Co-Expression of Nogo-A in Dopaminergic Neurons of the Human Substantia Nigra Pars Compacta Is Reduced in Parkinson’s Disease. Cells, 10(12) MDPI 10.3390/cells10123368

Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486

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Sarraj, Riad; Bionda, Marion; Dawson, Heather; Krupka, Niklas (2021). Recurrent dysphagia after bariatric surgery. Frontline gastroenterology, 12(7), pp. 700-701. BMJ Publishing Group 10.1136/flgastro-2020-101631

Kaufmann, Emilie; Schibli, Susanne; Trippel, Mafalda; Sokollik, Christiane (2021). Schwere prolongierte Diarrhoe im Säuglingsalter – eine Fallstudie. Swiss medical forum, 21(25-26), pp. 452-455. EMH Schweizerischer Ärzteverlag AG 10.4414/smf.2021.08653

2020

Katsidzira, Leolin; Mudombi, Wisdom F; Makunike-Mutasa, Rudo; Yilmaz, Bahtiyar; Blank, Annika; Rogler, Gerhard; Macpherson, Andrew; Vavricka, Stephan; Gangaidzo, Innocent; Misselwitz, Benjamin (2020). Inflammatory bowel disease in sub-Saharan Africa: a protocol of a prospective registry with a nested case-control study. BMJ open, 10(12), e039456. BMJ Publishing Group 10.1136/bmjopen-2020-039456

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Schucht, Philippe; Lee, Hee Ryung; Mezouar, Mohammed Hachem; Hewer, Ekkehard; Raabe, Andreas; Murek, Michael; Zubak, Irena; Goldberg, Johannes; Kovari, Eniko; Pierangelo, Angelo; Novikova, Tatiana (2020). Visualization of White Matter Fiber Tracts of Brain Tissue Sections with Wide-field Imaging Mueller Polarimetry. IEEE transactions on medical imaging, 39(12), pp. 4376-4382. Institute of Electrical and Electronics Engineers IEEE 10.1109/TMI.2020.3018439

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Meyer, Sara N.; Galván, José A.; Zahnd, Stefan; Sokol, Lena; Dawson, Heather; Lugli, Alessandro; Zlobec, Inti (2019). Co-expression of cytokeratin and vimentin in colorectal cancer highlights a subset of tumor buds and an atypical cancer-associated stroma. Human pathology, 87, pp. 18-27. Elsevier 10.1016/j.humpath.2019.02.002

Schnell, Bianca R.; Seipel, Katja; Bacher, Ulrike; Jeker, Barbara; Mueller, Beatrice U.; Banz, Yara; Novak, Urban; Pabst, Thomas (2019). Rebound Thrombocytosis after Induction Chemotherapy is a Strong Biomarker for Favorable Outcome in AML Patients. HemaSphere, 3(2), e180. Wolters Kluwer Health 10.1097/HS9.0000000000000180

Meda Spaccamela, Virginia; Valencia, Rocio G; Pastukhov, Oleksandr; Duppenthaler, Andrea; Dettmer, Matthias S.; Erb, Juliane; Steiner, Urs C; Hillinger, Sven; Speckmann, Carsten; Ehl, Stephan; Reichenbach, Janine; Siler, Ulrich (2019). High Levels of IL-18 and IFN-γ in Chronically Inflamed Tissue in Chronic Granulomatous Disease. Frontiers in immunology, 10, p. 2236. Frontiers Research Foundation 10.3389/fimmu.2019.02236

Neppl, Christina; Keller, Manuel D; Scherz, Amina; Dorn, Patrick; Schmid, Ralph A.; Zlobec, Inti; Berezowska, Sabina (2019). Comparison of the 7th and 8th Edition of the UICC/AJCC TNM Staging System in Primary Resected Squamous Cell Carcinomas of the Lung-A Single Center Analysis of 354 Cases. Frontiers in medicine, 6(196), p. 196. Frontiers 10.3389/fmed.2019.00196

Janser, Ariane F.; Tschan, Mario P.; Langer, Rupert (2019). The role of autophagy in HER2-targeted therapy. Swiss medical weekly, 149(149), w20138. EMH Media 10.4414/smw.2019.20138

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Seitz, Carina; Huang, Juan; Geiselhöringer, Anna-Lena; Galbani-Bianchi, Pamela; Michalek, Svenja; Phan, Truong San; Reinhold, Cindy; Dietrich, Lea; Schmidt, Christian; Corazza, Nadia; Delgado, Eugenia; Schnalzger, Theresa; Schoonjans, Kristina; Brunner, Thomas (2019). The orphan nuclear receptor LRH-1/NR5a2 critically regulates T cell functions. Science Advances, 5(7), eaav9732. American Association for the Advancement of Science 10.1126/sciadv.aav9732

Blank, Annika; Schenker, Carla; Dawson, Heather; Beldi, Guido; Zlobec, Inti; Lugli, Alessandro (2019). Evaluation of Tumor Budding in Primary Colorectal Cancer and Corresponding Liver Metastases Based on H&E and Pancytokeratin Staining. Frontiers in medicine, 6, p. 247. Frontiers 10.3389/fmed.2019.00247

Trepp, Roman; Hewer, Ekkehard; Perren, Aurel (2019). Hypophyse und Nebenniere. In: Cerny, Thomas; Karlin, Kirill (eds.) PathoMaps. Springer-Lehrbuch (pp. 137-141). Springer 10.1007/978-3-662-57439-3_20

Trepp, Roman; Perren, Aurel (2019). Schilddrüse und Nebenschilddrüse. In: Cerny, Thomas; Karlin, Kirill (eds.) PathoMaps. Springer-Lehrbuch (pp. 143-147). Springer-Verlag 10.1007/978-3-662-57439-3_21

Heinimann, Karl; Perren, Aurel (2019). Erbliche Tumorerkrankungen und Phakomatosen. In: Cerny, Thomas; Karlin, Kirill (eds.) PathoMaps. Springer-Lehrbuch (pp. 177-181). Springer-Verlag 10.1007/978-3-662-57439-3_25

Imboden, Sara; Nastic, Denis; Ghaderi, Mehran; Rydberg, Filippa; Rau, Tilman T.; Mueller, Michael D.; Epstein, Elisabeth; Carlson, Joseph W (2019). Phenotype of POLE-mutated endometrial cancer. PLoS ONE, 14(3), e0214318. Public Library of Science 10.1371/journal.pone.0214318

Karkampouna, Sofia; Grosjean, Joël; Klima, Irena; Genitsch, Vera; Sboner, A.; K. Y. Ng, C.; De Filippo, M.R.; Piscuoglio, S.; Spahn, M.; Rubin, Mark Andrew; Thalmann, G.N.; Kruithof-de Julio, Marianna (2019). Establishment of an androgen-sensitive patient derived xenograft model of prostate cancer. European Urology Supplements, 18(1), e1154. Elsevier 10.1016/S1569-9056(19)30831-0

De Gottardi, Jacqueline; Montani, Matteo; Angelillo-Scherrer, Anne; Rovó, Alicia; Berzigotti, Annalisa (2019). Hepatic sinusoidal hemophagocytosis with and without hemophagocytic lymphohistiocytosis. PLoS ONE, 14(12), e0226899. Public Library of Science 10.1371/journal.pone.0226899

Janser, Félice A.; Ney, Patricia; Teixeira Pinto, Marta; Langer, Rupert; Tschan, Mario P. (2019). The Chick Chorioallantoic Membrane (CAM) Assay as a Three-dimensional Model to Study Autophagy in Cancer Cells. Bio-protocol, 9(13) bio-protocol 10.21769/BioProtoc.3290

Berezowska, Sabina; Pöllinger, Alexander; Funke-Chambour, Manuela (2019). [Diagnostics of interstitial lung diseases in the multidisciplinary team]. Therapeutische Umschau, 76(7), pp. 375-381. Huber 10.1024/0040-5930/a001105

2018

Riether, Carsten; Pabst, Thomas; Höpner, Sabine; Bacher, Vera; Hinterbrandner, Magdalena; Banz, Yara; Müller, Rouven; Manz, Markus G.; Gharib, Walid H.; Ferreira, David; Bruggmann, Remy; Van Rompaey, Luc; Moshir, Mahan; Delahaye, Tim; Gandini, Domenica; Erzeel, Ellen; Hultberg, Anna; Fung, Samson; De Haard, Hans; Leupin, Nicolas; ... (2 December 2018). 2680 Argx-110 Targeting CD70, in Combination with Azacitidine, Shows Favorable Safety Profile and Promising Anti-Leukemia Activity in Newly Diagnosed AML Patients in an Ongoing Phase 1/2 Clinical Trial (Unpublished). In: ASCO 2018. 2. Dezember 2018.

Schoepfer, Alain; Blanchard, Carine; Dawson, Heather; Lucendo, Alfredo; Mauro, Aurelio; Ribi, Camillo; Safroneeva, Ekaterina; Savarino, Edoardo V; Penagini, Roberto (2018). Eosinophilic esophagitis: latest insights from diagnosis to therapy. Annals of the New York Academy of Sciences, 1434(1), pp. 84-93. Blackwell 10.1111/nyas.13731

Trippel, Mafalda; Slotta-Huspenina, Julia; Becker, Karen; Rau, Tilman; Paepke, Stefan; Maurer-Marti, Franziska; Langer, Rupert (2018). Macroscopic Evaluation of the Trimmed Frozen Block Is a Helpful Tool for Intraoperative Assessment of Resection Margins of Breast Cancer Specimens. International journal of surgical pathology, 26(8), pp. 693-700. Sage 10.1177/1066896918780346

Patil, Deepa T.; Hammer, Suntrea; Langer, Rupert; Yantiss, Rhonda K. (2018). Lymphocytic esophagitis: an update on histologic diagnosis, endoscopic findings, and natural history. Annals of the New York Academy of Sciences, 1434(1), pp. 185-191. Blackwell 10.1111/nyas.13710

El-Zimaity, Hala; Di Pilato, Vincenzo; Novella Ringressi, Maria; Brcic, Iva; Rajendra, Shanmugarajah; Langer, Rupert; Dislich, Bastian; Tripathi, Monika; Guindi, Maha; Riddell, Robert (2018). Risk factors for esophageal cancer: emphasis on infectious agents. Annals of the New York Academy of Sciences, 1434(1), pp. 319-332. Blackwell 10.1111/nyas.13858

Chou, Angela; Itchins, Malinda; de Reuver, Philip R; BSc, Jennifer Arena; BSc, Adele Clarkson; BSc, Amy Sheen; BSc, Loretta Sioson; MChD, Veronica Cheung; Perren, Aurel; Nahm, Christopher; Mittal, Anubhav; Samra, Jaswinder S; Pajic, Marina; Gill, Anthony J (2018). ATRX loss is an independent predictor of poor survival in pancreatic neuroendocrine tumours. Human pathology, 82, pp. 249-257. Elsevier 10.1016/j.humpath.2018.07.032

Berezowska, Sabina Anna (2018). [Lung cancer under stress]. Der Pathologe, 39(Suppl 2), pp. 208-214. Springer 10.1007/s00292-018-0506-y

Nisa, Lluís; Barras, David; Medova, Michaela; Aebersold, Daniel M.; Medo, Matúš; Poliaková, Michaela; Koch, Jonas; Bojaxhiu, Beat; Eliçin, Olgun; Dettmer, Matthias S.; Angelino, Paolo; Giger, Roland; Borner, Urs; Caversaccio, Marco D.; Carey, Thomas E; Ho, Liza; McKee, Thomas A; Delorenzi, Mauro; Zimmer, Yitzhak (2018). Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. Molecular cancer research, 16(12), pp. 1912-1926. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-18-0056

Neppl, Christina; Kaderli, Reto M.; Trepp, Roman; Schmitt, Anja M.; Berger, Martin D.; Wehrli, Marc; Seiler, Christian A.; Langer, Rupert (2018). Histology of Nivolumab-Induced Thyroiditis. Thyroid, 28(12), pp. 1727-1728. Mary Ann Liebert 10.1089/thy.2018.0418

Zhang, Shengye; Shaw-Boden, Jane; Banz, Yara; Bongoni, Anjan K; Taddeo, Adriano; Spirig, Rolf; Nolte, Marc W; Cowan, Peter J; Rieben, Robert (2018). Effects of C1 inhibitor on endothelial cell activation in a rat hind limb ischemia-reperfusion injury model. Journal of vascular surgery, 68(6 Suppl.), 209S-221S.e2. Elsevier 10.1016/j.jvs.2017.10.072

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Shumilov, Evgenii; Flach, Johanna; Kohlmann, Alexander; Banz Wälti, Yara; Bonadies, Nicolas; Fiedler, Martin; Pabst, Thomas; Bacher, Ulrike (2018). Current status and trends in the diagnostics of AML and MDS. Blood reviews, 32(6), pp. 508-519. Elsevier 10.1016/j.blre.2018.04.008

Jent, Philipp; Trippel, Mafalda; Frey, Manuel; Pöllinger, Alexander; Berezowska, Sabina; Langer, Rupert; Furrer, Hansjakob; Béguelin, Charles Antoine (2018). Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient. Open Forum Infectious Diseases, 5(11), ofy244. Oxford University Press 10.1093/ofid/ofy244

Trinh, Anne; Lädrach, Claudia; Dawson, Heather E.; Ten Hoorn, Sanne; Kuppen, Peter J K; Reimers, Marlies S; Koopman, Miriam; Punt, Cornelis J A; Lugli, Alessandro; Vermeulen, Louis; Zlobec, Inti (2018). Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data. British journal of cancer, 119(10), pp. 1244-1251. Nature Publishing Group 10.1038/s41416-018-0230-7

Ersözlü, Sara; Desnick, Robert J; Huynh-Do, Uyen; Canaan-Kühl, Sima; Barbey, Frédéric; Genitsch, Vera; Mueller, Thomas F; Cheetham, Marcus; Flammer, Andreas J; Schaub, Stefan; Nowak, Albina (2018). Long-term Outcomes of Kidney Transplantation in Fabry Disease. Transplantation, 102(11), pp. 1924-1933. Wolters Kluwer Health 10.1097/TP.0000000000002252

Rindi, Guido; Klersy, Catherine; Albarello, Luca; Baudin, Eric; Bianchi, Antonio; Büchler, Markus W; Caplin, Martyn; Couvelard, Anne; Cros, Jérôme; de Herder, Wouter W; Delle Fave, Gianfranco; Doglioni, Claudio; Federspiel, Birgitte; Fischer, Lars; Fusai, Giuseppe; Gavazzi, Francesca; Hansen, Carsten; Inzani, Frediano; Jann, Henning; Komminoth, Paul; ... (2018). COMPETITIVE TESTING THE WHO 2010 VS THE WHO 2017 GRADING OF PANCREAS NEUROENDOCRINE NEOPLASIA: DATA FROM A LARGE INTERNATIONAL COHORT STUDY. Neuroendocrinology, 107(4), pp. 375-386. Karger 10.1159/000494355

Janser, Félice A.; Adams, Olivia Joan; Bütler, Vanessa; Bill, Anna Magdalena; Dislich, Bastian; Seiler, Christian A.; Kröll, Dino; Langer, Rupert; Tschan, Mario (2018). Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells. International journal of molecular sciences, 19(10) Molecular Diversity Preservation International MDPI 10.3390/ijms19103069

Krug, Sebastian; Abbassi, Rami; Griesmann, Heidi; Sipos, Bence; Wiese, Dominik; Rexin, Peter; Blank, Annika; Perren, Aurel; Haybaeck, Johannes; Hüttelmaier, Stefan; Rinke, Anja; Gress, Thomas M; Michl, Patrick (2018). Therapeutic Targeting of Tumor-Associated Macrophages in Pancreatic Neuroendocrine Tumors. International journal of cancer, 143(7), pp. 1806-1816. Wiley-Blackwell 10.1002/ijc.31562

Erdös, Gabor; Rummel, Christian; Basciani, Reto Marco; Verma, Rajeev Kumar; Carrel, Thierry; Banz Wälti, Yara; Eberle, Balthasar; Schroth, Gerhard (2018). Limitations of Current Near-Infrared Spectroscopy Configuration in Detecting Focal Cerebral Ischemia During Cardiac Surgery: An Observational Case-Series Study. Artificial organs, 42(10), pp. 1001-1009. Wiley-Blackwell 10.1111/aor.13150

Dzhonova, Dzhuliya Vihrenova; Olariu, Radu; Leckenby, Jonathan Ian; Banz Wälti, Yara; Prost, Jean-Christophe; Dhayani, Ashish; Vemula, Praveen K; Vögelin, Esther; Taddeo, Adriano; Rieben, Robert (2018). Local injections of tacrolimus-loaded hydrogel reduce systemic immunosuppression-related toxicity in vascularized composite allotransplantation. Transplantation, 102(10), pp. 1684-1694. Lippincott Williams & Wilkins 10.1097/TP.0000000000002283

Zinnall, Ulrike; Weyerer, Veronika; Compérat, Eva; Camparo, Philippe; Gaisa, Nadine T; Knuechel-Clarke, Ruth; Perren, Aurel; Lugli, Alessandro; Toma, Marieta; Baretton, Gustavo; Kristiansen, Glen; Wirtz, Ralf M; Cheng, Liang; Wullich, Bernd; Stoehr, Robert; Hartmann, Arndt; Bertz, Simone (2018). Micropapillary urothelial carcinoma: evaluation of HER2 status and immunohistochemical characterization of the molecular subtype. Human pathology, 80, pp. 55-64. Elsevier 10.1016/j.humpath.2018.05.022

Bacher, Vera Ulrike; Porret, Naomi; Joncourt, Raphael; Sanz, Javier; Aliu, Nijas; Wiedemann, Gertrud; Jeker, Barbara; Banz Wälti, Yara; Pabst, Thomas (2018). Pitfalls in the molecular follow up of mutant acute myeloid leukemia. Haematologica - the hematology journal, 103(10), e486-e488. Ferrata-Storti Foundation 10.3324/haematol.2018.192104

Farag, Sarah Ahmed Ibrahim; Jeker, Barbara; Bacher, Vera Ulrike; Mansouri Taleghani, Behrouz; Müller, Beatrice Ursula; Novak, Urban; Pabst Müller, Thomas Niklaus (2018). Dose-intensified bendamustine and melphalan (BenMel) conditioning before second autologous transplantation in myeloma patients. Hematological oncology, 36(4), pp. 671-678. Wiley 10.1002/hon.2546

Graule, Janina; Uth-Gottardi, Kristin; Fischer, Elia Luca; Centeno Ramos, Irene; Galván Hernández, José Alberto; Eichmann, Micha David; Rau, Tilman; Langer, Rupert; Dawson, Heather; Nitsche, Ulrich; Traeger, Peter; Berger, Martin Dave; Schnüriger, Beat; Hädrich, Marion; Studer, Peter; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2018). CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway. Clinical epigenetics, 10(1), p. 120. Springer 10.1186/s13148-018-0548-2

Häfliger, Pascal; Graff, Julien; Rubin, Matthias; Stooss, Amandine; Dettmer, Matthias S.; Altmann, Karl-Heinz; Gertsch, Jürg; Charles, Roch-Philippe (2018). The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model. Journal of experimental & clinical cancer research, 37(1), p. 234. BioMed Central 10.1186/s13046-018-0907-z

Niklaus, Nicolas Jan; Humbert, Magali; Tschan, Mario (2018). Cisplatin sensitivity in breast cancer cells is associated with particular DMTF1 splice variant expression. Biochemical and biophysical research communications, 503(4), pp. 2800-2806. Academic Press 10.1016/j.bbrc.2018.08.042

Wartenberg, Martin; Cibin, Silvia; Zlobec, Inti; Vassella, Erik; Eppenberger-Castori, Serenella; Terracciano, Luigi; Eichmann, Micha David; Worni, Mathias; Gloor, Beat; Perren, Aurel; Karamitopoulou, Evanthia (2018). Integrated Genomic and Immunophenotypic Classification of Pancreatic Cancer Reveals Three Distinct Subtypes with Prognostic/Predictive Significance. Clinical cancer research, 24(18), pp. 4444-4454. American Association for Cancer Research 10.1158/1078-0432.CCR-17-3401

Bürki, Susanne; Shumilov, Evgenii; Bonadies, Nicolas; Flach, Johanna; Legros, Myriam; Banz, Yara; Oppliger-Leibundgut, Elisabeth; Fiedler, Martin; Angelillo, Anne; Rovó, Alicia; Bacher, Vera Ulrike (2018). Coincidence of 5q deletion and the JAK2V617F mutation: report of two patients with overlapping myelodysplastic and myeloproliferative features and review of the literature. Leukemia & lymphoma, 59(9), pp. 2233-2237. Informa Healthcare 10.1080/10428194.2017.1416367

Sorbye, Halfdan; Baudin, Eric; Perren, Aurel (2018). The Problem of High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms: Well-Differentiated Neuroendocrine Tumors, Neuroendocrine Carcinomas, and Beyond. Endocrinology and metabolism clinics of North America, 47(3), pp. 683-698. Elsevier 10.1016/j.ecl.2018.05.001

Abiraj, Keelara; Ursillo, Samer; Tamma, Maria Luisa; Rylova, Svetlana N; Waser, Beatrice; Constable, Edwin C; Fani, Melpomeni; Nicolas, Guillaume P; Reubi, Jean Claude; Maecke, Helmut R (2018). The tetraamine chelator outperforms HYNIC in a new technetium-99m-labelled somatostatin receptor 2 antagonist. EJNMMI research, 8(1), p. 75. Springer 10.1186/s13550-018-0428-y

Reinhardt, Annekathrin; Stichel, Damian; Schrimpf, Daniel; Sahm, Felix; Korshunov, Andrey; Reuss, David E; Koelsche, Christian; Huang, Kristin; Wefers, Annika K; Hovestadt, Volker; Sill, Martin; Gramatzki, Dorothee; Felsberg, Joerg; Reifenberger, Guido; Koch, Arend; Thomale, Ulrich-W; Becker, Albert; Hans, Volkmar H; Prinz, Marco; Staszewski, Ori; ... (2018). Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations. Acta neuropathologica, 136(2), pp. 273-291. Springer 10.1007/s00401-018-1837-8

Feddern, Nina; Amendt, Jens; Schyma, Christian; Jackowski, Christian; Tschui, Joëlle (2018). A preliminary study about the spatiotemporal distribution of forensically important blow flies (Diptera: Calliphoridae) in the area of Bern, Switzerland. Forensic science international, 289, pp. 57-66. Elsevier Scientific Publ. Ireland 10.1016/j.forsciint.2018.05.022

Eichhorn, Philip; Andraschke, Udo; Dross, Fritz; Geppert, Carol I; Hartmann, Arndt; Rau, Tilman (2018). Restoration of an academic historical gross pathology collection-refreshed impact on current medical teaching? Virchows Archiv, 473(2), pp. 219-228. Springer 10.1007/s00428-018-2369-2

Henfling, Mieke; Perren, Aurel; Schmitt, Anja Maria; Saddig, Christiane M; Starke, Achim A; Riedl, Robert G; Versleijen-Jonkers, Yvonne M H; Sprij-Mooij, Diane M; Ramaekers, Frans C S; Hofland, Leo; Speel, Ernst-Jan M (2018). The IGF pathway is activated in insulinomas but downregulated in metastatic disease. (In Press). Endocrine-related cancer BioScientifica Ltd. 10.1530/ERC-18-0222

Glück, Astrid Andreina; Orlando, Eleonora; Leiser, Dominic; Poliakova, Michaela; Nisa Hernández, Lluís; Quintin, Aurelie; Gavini, Jacopo; Keogh-Stroka, Deborah M.; Berezowska, Sabina; Bubendorf, Lukas; Blaukat, Andree; Aebersold, Daniel; Medova, Michaela; Zimmer, Yitzhak (2018). Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia. Oncogene, 37(30), pp. 4181-4196. Nature Publishing Group 10.1038/s41388-018-0256-6

Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3

Bill, Ruben; Montani, Matteo; Blum, Benedikt; Dufour, Jean-François; Escher, Robert; Bühlmann, Michael (2018). Favorable response to mammalian target of rapamycin inhibition in a young patient with unresectable fibrolamellar carcinoma of the liver. Hepatology, 68(1), pp. 384-386. Wiley Interscience 10.1002/hep.29853

Karamitopoulou, Evanthia; Wartenberg, Martin; Zlobec, Inti; Cibin, Silvia; Worni, Mathias; Gloor, Beat; Lugli, Alessandro (2018). Tumour budding in pancreatic cancer revisited: validation of the ITBCC scoring system. Histopathology, 73(1), pp. 137-146. Wiley 10.1111/his.13508

Jaccard, Claudia M.; Plüss, Emanuel; Doulberis, Michael; Trippel, Mafalda; Banz, Yara (2018). Ungewöhnliche Ursache eines Kapillarlecksyndroms. Swiss medical forum, 18(24), p. 517. EMH Schweizerischer Ärzteverlag AG 10.4414/smf.2017.03202

Schär, Ralph T.; Hewer, Ekkehard; Ulrich, Christian Thomas (2018). Langerhans Cell Histiocytosis of the Adult Cervical Spine: A Case Report and Literature Review. Journal of neurological surgery. Part A, Central European neurosurgery, 80(1), pp. 49-52. Thieme 10.1055/s-0038-1655769

Nicolas, Guillaume P; Beykan, Seval; Bouterfa, Hakim; Kaufmann, Jens; Bauman, Andreas; Lassmann, Michael; Reubi, Jean Claude; Rivier, Jean E F; Maecke, Helmut R; Fani, Melpomeni; Wild, Damian (2018). Safety, Biodistribution, and Radiation Dosimetry of Ga-OPS202 in Patients with Gastroenteropancreatic Neuroendocrine Tumors: A Prospective Phase I Imaging Study. Journal of nuclear medicine, 59(6), pp. 909-914. Society of Nuclear Medicine 10.2967/jnumed.117.199737

Pagès, Franck; Mlecnik, Bernhard; Marliot, Florence; Bindea, Gabriela; Ou, Fang-Shu; Bifulco, Carlo; Lugli, Alessandro; Zlobec, Inti; Rau, Tilman T.; Berger, Martin D.; Nagtegaal, Iris D; Vink-Börger, Elisa; Hartmann, Arndt; Geppert, Carol; Kolwelter, Julie; Merkel, Susanne; Grützmann, Robert; Van den Eynde, Marc; Jouret-Mourin, Anne; Kartheuser, Alex; ... (2018). International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study. Lancet, 391(10135), pp. 2128-2139. Elsevier 10.1016/S0140-6736(18)30789-X

García-Martín, Ana B; Zwicky, Pascale; Gruber, Thomas; Matti, Christoph; Moalli, Federica; Stein, Jens Volker; Francisco, David; Enzmann, Gaby; Levesque, Mitchell P; Hewer, Ekkehard; Lyck, Ruth (2018). VLA-4 mediated adhesion of melanoma cells on the blood-brain barrier is the critical cue for melanoma cell intercalation and barrier disruption. Journal of cerebral blood flow and metabolism, 39(10), pp. 1995-2010. Sage 10.1177/0271678X18775887

Hewer, Ekkehard; Hammer, Caroline; Fricke-Vetsch, Daniela; Baumann, Cinzia; Perren, Aurel; Schmitt, Anja M. (2018). Implementation of a ‘lean’ cytopathology service: towards routine same-day reporting. Journal of clinical pathology, 71(5), pp. 395-401. BMJ Publishing Group 10.1136/jclinpath-2017-204504

Wang, Junhua; Goepfert, Christine; Mueller, Norbert; Piersigilli, Alessandra; Lin, Renyong; Wen, Hao; Vuitton, Dominique A.; Vuitton, Lucine; Müller, Christoph; Gottstein, Bruno (2018). Larval Echinococcus multilocularis infection reduces dextran sulphate sodium-induced colitis in mice by attenuating T helper type 1/type 17-mediated immune reactions. Immunology, 154(1), pp. 76-88. Wiley-Blackwell 10.1111/imm.12860

Nock, Berthold A; Charalambidis, David; Sallegger, Werner; Waser, Beatrice; Mansi, Rosalba; Nicolas, Guillaume P; Ketani, Eleni; Nikolopoulou, Anastasia; Fani, Melpomeni; Reubi, Jean-Claude; Maina, Theodosia (2018). New Gastrin Releasing Peptide Receptor-Directed [Tc]Demobesin 1 Mimics: Synthesis and Comparative Evaluation. Journal of medicinal chemistry, 61(7), pp. 3138-3150. American Chemical Society 10.1021/acs.jmedchem.8b00177

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Baumgartner, Ulrich; Berger, Fabienne; Hashemi Gheinani, Ali; Burgener, Sabrina Sofia; Monastyrskaya-Stäuber, Katia; Vassella, Erik (2018). miR-19b enhances proliferation and apoptosis resistance via the EGFR signaling pathway by targeting PP2A and BIM in non-small cell lung cancer. Molecular cancer, 17(1), p. 44. BioMed Central 10.1186/s12943-018-0781-5

Langer, Rupert; Becker, Karen (2018). Tumor regression grading of gastrointestinal cancers after neoadjuvant therapy. Virchows Archiv, 472(2), pp. 175-186. Springer 10.1007/s00428-017-2232-x

Kröll, Dino; Noser, Laura; Erdem, Suna; Zlobec, Inti; Storni, Federico Lorenzo; Arnold, Dominik; Dislich, Bastian; Seiler, Christian A.; Candinas, Daniel; Langer, Rupert (2018). Application of the 8th edition of the AJCC yTNM staging system shows improved prognostication in a single center cohort of esophageal carcinomas. Surgical oncology, 27(1), pp. 100-105. Elsevier 10.1016/j.suronc.2017.12.005

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Keller, Manuel D; Neppl, Christina; Irmak, Yasin; Hall, Sean; Schmid, Ralph; Langer, Rupert; Berezowska, Sabina Anna (2018). Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases. Modern pathology, 31(1), pp. 101-110. Nature Publishing Group 10.1038/modpathol.2017.111

Laedrach, C; Salhia, B; Cihoric, Nikola; Zlobec, Inti; Tapia, C (2018). Immunophenotypic profile of tumor buds in breast cancer. Pathology, research and practice, 214(1), pp. 25-29. Elsevier 10.1016/j.prp.2017.11.023

Schmaranzer, Florian; Arendt, L; Lerch, Till; Steppacher, Simon Damian; Nuss, K; Wolfer, N; Dawson, Heather; von Rechenberg, B; Kircher, PR; Tannast, Moritz (2018). Femoral osteochondroplasty can be performed effectively without the risk of avascular necrosis or femoral neck fractures in an experimental ovine FAI model. Osteoarthritis and cartilage, 26(1), pp. 128-137. Elsevier 10.1016/j.joca.2017.10.009

Sadowski, Samira Mercedes; Christ, Emanuel; Bedat, Benoit; Kollár, Attila; Karenovics, Wolfram; Perren, Aurel; Triponez, Frederic (2018). Nationwide multicenter study on the management of pulmonary neuroendocrine (carcinoid) tumors. Endocrine Connections, 7(1), pp. 8-15. BioScientifica 10.1530/EC-17-0271

Schürch, Christian; Federmann, Birgit; Quintanilla-Martinez, Leticia; Fend, Falko (2018). Tumor Heterogeneity in Lymphomas: A Different Breed. Pathobiology, 85(1-2), pp. 130-145. Karger 10.1159/000475530

Brasseit, Jennifer; Kwong Chung, Cheong Kwet Choy; Noti, Mario; Zysset, Daniel; Hoheisel-Dickgreber, Nina; Genitsch, Vera; Corazza, Nadia; Müller, Christoph (2018). Divergent Roles of Interferon-γ and Innate Lymphoid Cells in Innate and Adaptive Immune Cell-Mediated Intestinal Inflammation. Frontiers in immunology, 9(23) Frontiers Research Foundation 10.3389/fimmu.2018.00023

Smith, Richard; Wang, Jiaxi; Seymour, Colin; Fernandez-Palomo, Cristian; Fazzari, Jennifer; Schültke, Elisabeth; Bräuer-Krisch, Elke; Laissue, Jean; Schroll, Christian; Mothersill, Carmel (2018). Homogenous and Microbeam X-Ray Radiation Induces Proteomic Changes in the Brains of Irradiated Rats and in the Brains of Nonirradiated Cage Mate Rats. Dose-response, 16(1), p. 1559325817750068. Sage Publications 10.1177/1559325817750068

Capper, David; Jones, David T. W.; Sill, Martin; Hovestadt, Volker; Schrimpf, Daniel; Sturm, Dominik; Koelsche, Christian; Sahm, Felix; Chavez, Lukas; Reuss, David E.; Kratz, Annekathrin; Wefers, Annika K.; Huang, Kristin; Pajtler, Kristian W.; Schweizer, Leonille; Stichel, Damian; Olar, Adriana; Engel, Nils W.; Lindenberg, Kerstin; Harter, Patrick N.; ... (2018). DNA methylation-based classification of central nervous system tumours. Nature, 555(7697), pp. 469-474. Macmillan Journals Ltd. 10.1038/nature26000

Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795

Adams, Olivia; Janser, Félice A.; Dislich, Bastian; Berezowska, Sabina; Humbert, Magali; Seiler, Christian A.; Kroell, Dino; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Tschan, Mario P.; Langer, Rupert (2018). A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. PLoS ONE, 13(6), e0197610. Public Library of Science 10.1371/journal.pone.0197610

Li, Leanne; Zeng, Qiqun; Bhutkar, Arjun; Galván Hernández, José Alberto; Karamitopoulou, Evanthia; Noordermeer, Daan; Peng, Mei-Wen; Piersigilli, Alessandra; Perren, Aurel; Zlobec, Inti; Robinson, Hugh; Iruela-Arispe, M. Luisa; Hanahan, Douglas (2018). GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth. Cancer cell, 33(4), 736-751.e5. Cell Press 10.1016/j.ccell.2018.02.011

Banz Wälti, Yara; Berezowska, Sabina Anna; de Leval, Laurence; Rubbia-Brandt, Laura; Tolnay, Markus; Moch, Holger; Perren, Aurel; Hewer, Ekkehard (2018). Advancing synoptic cancer reports beyond English: the University of Bern/PathoLink approach. Virchows Archiv, 473(5), pp. 655-656. Springer 10.1007/s00428-018-2431-0

Langer, Rupert; Neppl, Christina; Keller, Manuel; Schmid, Ralph; Tschan, Mario; Berezowska, Sabina Anna (2018). Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas. Cancers, 10(9), p. 281. MDPI AG 10.3390/cancers10090281

Shukla, Sachet A.; Bachireddy, Pavan; Schilling, Bastian; Galonska, Christina; Zhan, Qian; Bango, Clyde; Langer, Rupert; Lee, Patrick C.; Gusenleitner, Daniel; Keskin, Derin B.; Babadi, Mehrtash; Mohammad, Arman; Gnirke, Andreas; Clement, Kendell; Cartun, Zachary J.; Van Allen, Eliezer M.; Miao, Diana; Huang, Ying; Snyder, Alexandra; Merghoub, Taha; ... (2018). Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade. Cell, 173(3), 624-633.e8. Cell Press 10.1016/j.cell.2018.03.026

Slotta-Huspenina, Julia; Drecoll, Enken; Feith, Marcus; Habermehl, Daniel; Combs, Stephanie; Weichert, Wilko; Bettstetter, Marcus; Becker, Karen; Langer, Rupert (2018). MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus. Journal of translational medicine, 16(1), p. 109. BioMed Central 10.1186/s12967-018-1492-9

Boxberg, Melanie; Steiger, Katja; Lenze, Ulrich; Rechl, Hans; von Eisenhart-Rothe, Rüdiger; Wörtler, Klaus; Weichert, Wilko; Langer, Rupert; Specht, Katja (2018). PD-L1 and PD-1 and characterization of tumor-infiltrating lymphocytes in high grade sarcomas of soft tissue – prognostic implications and rationale for immunotherapy. Oncoimmunology, 7(3), e1389366. Taylor & Francis 10.1080/2162402x.2017.1389366

Dzhonova, Dzhuliya Vihrenova; Olariu, Radu; Leckenby, Jonathan Ian; Dhayani, Ashish; Vemula, Praveen Kumar; Prost, Jean-Christophe; Banz, Yara; Taddeo, Adriano; Rieben, Robert (2018). Local release of tacrolimus from hydrogel-based drug delivery system is controlled by inflammatory enzymes in vivo and can be monitored non-invasively using in vivo imaging. PLoS ONE, 13(8), e0203409. Public Library of Science 10.1371/journal.pone.0203409

Kölzer, Viktor H; Gisler, Aline; Hanhart, Jonathan C; Griss, Johannes; Wagner, Stephan N; Willi, Niels; Cathomas, Gieri; Sachs, Melanie; Kempf, Werner; Thommen, Daniela S; Mertz, Kirsten D (2018). Digital image analysis improves precision of PD-L1 scoring in cutaneous melanoma. Histopathology, 73(3), pp. 397-406. Blackwell Scientific Publications 10.1111/his.13528

Blank, Annika; Roberts, Daniel Edward; Dawson, Heather; Zlobec, Inti; Lugli, Alessandro (2018). Tumor Heterogeneity in Primary Colorectal Cancer and Corresponding Metastases. Does the Apple Fall Far From the Tree? Frontiers in medicine, 5, p. 234. Frontiers 10.3389/fmed.2018.00234

Körner, M.; Waser, Beatrice; Christ, E.; Beck, J.; Reubi, J.C. (2018). A Critical Evaluation of sst3 and sst5 Immunohistochemistry in Human Pituitary Adenomas. Neuroendocrinology, 106(2), pp. 116-127. Karger 10.1159/000472563

Flückiger, Miriam; Oikonomou, Vasileios; Linas, Ioannis; Dettmer, Matthias; Dawson, Heather; Macpherson, Andrew J (2018). How Lymphogranuloma venereum mimics inflammatory bowel disease-a case report. Swiss medical weekly, 148, 18S-18S. EMH Schweizerischer Ärzteverlag

Stivala, S; Baerenwaldt, A; Codilupi, T; Ghosh, N; Hao-Shen, H; Dirnhofer, S; Dettmer, Matthias; Simillion, C; Chiu, S; Keller, M (2018). ERK and MEK kinases as novel therapeutic targets in myeloproliferative neoplasms based on bypass MAPK pathway activation. Swiss medical weekly, 148, 28S-28S. EMH Schweizerischer Ärzteverlag

Cernea, Ana; Fernández-Martínez, Juan Luis; deAndrés-Galiana, Enrique J.; deAndrés-Galiana, Enrique J.; Galván, José A.; García Pravia, Carmen; Zhang, Jinxin (2018). Analysis of Clinical Prognostic Variables for Triple Negative Breast Cancer Histological Grading and Lymph Node Metastasis. Journal of medical informatics and decision making, 1(1), pp. 14-36. Open Access Pub 10.14302/issn.2641-5526.jmid-18-2488

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Diebold, Matthias; Soltermann, Alex; Hottinger, Selma; Haile, Sarah R; Bubendorf, Lukas; Komminoth, Paul; Jochum, Wolfram; Grobholz, Rainer; Theegarten, Dirk; Berezowska, Sabina Anna; Darwiche, Kaid; Oezkan, Filiz; Kohler, Malcolm; Franzen, Daniel P (2017). Prognostic value of MIB-1 proliferation index in solitary fibrous tumors of the pleura implemented in a new score - a multicenter study. Respiratory research, 18(1), p. 210. BioMed Central 10.1186/s12931-017-0693-8

Faget, Julien; Groeneveld, Svenja; Boivin, Gael; Sankar, Martial; Zangger, Nadine; Garcia, Miguel; Guex, Nicolas; Zlobec, Inti; Steiner, Loïc; Piersigilli, Alessandra; Xenarios, Ioannis; Meylan, Etienne (2017). Neutrophils and Snail Orchestrate the Establishment of a Pro-tumor Microenvironment in Lung Cancer. Cell reports, 21(11), pp. 3190-3204. Cell Press 10.1016/j.celrep.2017.11.052

Uccella, Silvia; Blank, Annika; Maragliano, Roberta; Sessa, Fausto; Perren, Aurel; La Rosa, Stefano (2017). Calcitonin-Producing Neuroendocrine Neoplasms of the Pancreas: Clinicopathological Study of 25 Cases and Review of the Literature. Endocrine pathology, 28(4), pp. 351-361. Springer 10.1007/s12022-017-9505-4

Amstutz, Ursula; Grob, Tobias; Largiadèr, Carlo Rodolfo; Vassella, Erik (2017). Liquid Biopsy: Tumorgenetik in Körperflüssigkeiten. Pipette - Swiss laboratory medicine(6), pp. 11-12. EMH Schweizerischer Ärzteverlag AG

Rölli, Matthias Andreas; Ruffieux-Daidiée, Dorothée; Stooss, Amandine; El Mokh, Oussama; Phillips, Wayne A; Dettmer, Matthias; Charles, Roch-Philippe (2017). PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors. OncoTarget, 8(61), pp. 103207-103222. Impact Journals LLC 10.18632/oncotarget.21732

Saurer, Leslie; Zysset, Daniel; Rihs, Silvia; Mager, Lukas; Gusberti, Matteo; Simillion, Cedric; Lugli, Alessandro; Zlobec, Inti; Krebs, Philippe; Müller, Christoph (2017). TREM-1 promotes intestinal tumorigenesis. Scientific Reports, 7(1), p. 14870. Nature Publishing Group 10.1038/s41598-017-14516-4

Hewer, Ekkehard; Prebil, Nadine; Berezowska, Sabina Anna; Gutt-Will, M.; Schucht, Philippe; Dettmer, Matthias; Vassella, Erik (2017). Diagnostic implications of TERT promoter mutation status in diffuse gliomas in a routine clinical setting. Virchows Archiv, 471(5), pp. 641-649. Springer 10.1007/s00428-017-2216-x

Wiedmer, Tabea; Blank, Annika; Pantasis, Sophia; Normand, Lea Elena Haaning; Bill, Ruben; Krebs, Philippe; Tschan, Mario; Marinoni, Ilaria; Perren, Aurel (2017). Autophagy inhibition improves sunitinib efficacy in pancreatic neuroendocrine tumors via a lysosome-dependent mechanism. Molecular cancer therapeutics, 16(11), pp. 2502-2515. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-17-0136

Blank, Annika; Dawson, Heather; Hammer, Caroline; Perren, Aurel; Lugli, Alessandro (2017). [Lean management in the pathology laboratory]. Der Pathologe, 38(6), pp. 540-544. Springer 10.1007/s00292-017-0388-4

Galon, Jerome; Lugli, Alessandro; Bifulco, Carlo; Pages, Franck; Masucci, Giuseppe; Marincola, Francesco M; Ascierto, Paolo A (2017). World-Wide Immunoscore Task Force: meeting report from the "Melanoma Bridge", Napoli, November 30th-December 3rd, 2016. Journal of translational medicine, 15(1), p. 212. BioMed Central 10.1186/s12967-017-1310-9

Schläfli, Anna; Isakson, Pauline; Garattini, E; Simonsen, Anne; Tschan, Mario (2017). The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells. Scientific Reports, 7(1), p. 12980. Nature Publishing Group 10.1038/s41598-017-12734-4

Tegtmeyer, Nicole; Wessler, Silja; Necchi, Vittorio; Rohde, Manfred; Harrer, Aileen; Rau, Tilman; Asche, Carmen Isabell; Boehm, Manja; Loessner, Holger; Figueiredo, Ceu; Naumann, Michael; Palmisano, Ralf; Solcia, Enrico; Ricci, Vittorio; Backert, Steffen (2017). Helicobacter pylori Employs a Unique Basolateral Type IV Secretion Mechanism for CagA Delivery. Cell host & microbe, 22(4), 552-560.e5. Cell Press 10.1016/j.chom.2017.09.005

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Sartori, Elsa; Langer, Rupert; Vassella, Erik; Hewer, Ekkehard; Schucht, Philippe; Zlobec, Inti; Berezowska, Sabina Anna (2017). Low co-expression of epidermal growth factor receptor and its chaperone heat shock protein 90 is associated with worse prognosis in primary glioblastoma, IDH-wild-type. Oncology reports, 38(4), pp. 2394-2400. Spandidos Publications 10.3892/or.2017.5863

Olariu, Radu; Denoyelle, Julie Sophie Cécile; Leclère, Franck-Marie Patrick; Dzhonova, Dzhuliya Vihrenova; Gajanayake, Thusitha; Banz Wälti, Yara; Hayoz, Michael; Constantinescu, Mihai Adrian; Rieben, Robert; Vögelin, Esther; Taddeo, Adriano (2017). Intra-graft injection of tacrolimus promotes survival of vascularized composite allotransplantation. The journal of surgical research, 218, pp. 49-57. Elsevier 10.1016/j.jss.2017.05.046

Dumont, Charles Edouard; Keel, Marius; Djonov, Valentin; Haefeli, Pascal; Schmid, Timo Georg Johannes; Olariu, Radu; Cullmann, Jennifer; Bastian, Johannes Dominik (2017). The Pararectus approach provides secure access to the deep circumflex iliac vessel for harvest of a large sized and vascularized segment of the iliac crest. Injury - international journal of the care of the injured, 48(10), pp. 2169-2173. Elsevier 10.1016/j.injury.2017.08.013

Klöppel, Günter; Klimstra, David S; Hruban, Ralph H; Adsay, Volkan; Capella, Carlo; Couvelard, Anne; Komminoth, Paul; La Rosa, Stefano; Ohike, Nobuyuki; Osamura, Robert Y; Perren, Aurel; Scoazec, Jean-Yves; Rindi, Guido (2017). Pancreatic neuroendocrine tumors: update on the new World Health Organization classification. AJSP: Reviews & Reports, 22(5), pp. 233-239. 10.1097/PCR.0000000000000211

Mele, Valentina; Sokol, Lena; Kölzer, Viktor; Pfaff, Dennis; Muraro, Manuele Giuseppe; Keller, Irene; Zahnd, Stefan Patrick; Centeno Ramos, Irene; Terracciano, Luigi Maria; Dawson, Heather; Zlobec, Inti; Iezzi, Giandomenica; Lugli, Alessandro (2017). The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer. OncoTarget, 8(41), pp. 70617-70629. Impact Journals LLC 10.18632/oncotarget.19904

Marti, Nesa Magdalena; Malikova, Jana; Galván Hernández, José Alberto; Aebischer, Maude; Janner, Marco; Sumnik, Zdenek; Obermannova, Barbora; Escher, Geneviève; Perren, Aurel; Flück Pandey, Christa Emma (2017). Androgen production in pediatric adrenocortical tumors may occur via both the classic and/or the alternative backdoor pathway. Molecular and cellular endocrinology, 452, pp. 64-73. Elsevier Ireland 10.1016/j.mce.2017.05.014

Grand, Marie; Thielken, Andrea; Perren, Aurel; Komminoth, Paul (2017). Pathologie neuroendokriner Neoplasien: Angepasste Klassifikation, Gradierung und TNM Einteilung 2017: “Nomen est omen?”. Therapeutische Umschau, 74(4), pp. 190-196. Huber 10.1024/0040-5930/a000903

Di Domenico, Annunziata; Wiedmer, Tabea; Marinoni, Ilaria; Perren, Aurel (2017). Genetic and epigenetic drivers of neuroendocrine tumours (NET). Endocrine-related cancer, 24(9), R315-R334. BioScientifica Ltd. 10.1530/ERC-17-0012

Galleberg, R B; Knigge, U; Tiensuu Janson, E; Vestermark, L W; Haugvik, S-P; Ladekarl, M; Langer, S W; Grønbæk, H; Österlund, P; Hjortland, G O; Assmus, J; Tang, L; Perren, Aurel; Sorbye, H (2017). Results after surgical treatment of liver metastases in patients with high-grade gastroenteropancreatic neuroendocrine carcinomas. European journal of surgical oncology EJSO, 43(9), pp. 1682-1689. Elsevier 10.1016/j.ejso.2017.04.010

Alderson, Derek; Cunningham, David; Nankivell, Matthew; Blazeby, Jane M; Griffin, S Michael; Crellin, Adrian; Grabsch, Heike I; Langer, Rupert; Pritchard, Susan; Okines, Alicia; Krysztopik, Richard; Coxon, Fareeda; Thompson, Joyce; Falk, Stephen; Robb, Clare; Stenning, Sally; Langley, Ruth E (2017). Neoadjuvant cisplatin and fluorouracil versus epirubicin, cisplatin, and capecitabine followed by resection in patients with oesophageal adenocarcinoma (UK MRC OE05): an open-label, randomised phase 3 trial. The lancet oncology, 18(9), pp. 1249-1260. Elsevier 10.1016/S1470-2045(17)30447-3

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Niklaus, Monique; Adams, Olivia Joan; Berezowska, Sabina Anna; Zlobec, Inti; Graber, Franziska; Slotta-Huspenina, Julia; Nitsche, Ulrich; Rosenberg, Robert; Tschan, Mario; Langer, Rupert (2017). Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer. OncoTarget, 8(33), pp. 54604-54615. Impact Journals LLC 10.18632/oncotarget.17554

Abd El Hafez, Mai Moustafa Ahmed; Shaw-Boden, Jane; Sutter, Damian; Schnider, Jonas Thomas; Banz Wälti, Yara; Jenni, Hansjörg; Vögelin, Esther; Constantinescu, Mihai Adrian; Rieben, Robert (2017). Effect of C1-INH on ischemia/reperfusion injury in a porcine limb ex vivo perfusion model. Molecular immunology, 88, pp. 116-124. Elsevier 10.1016/j.molimm.2017.06.021

Murone, Maximilien; Radpour, Ramin; Attinger, Antoine; Chessex, Anne Vaslin; Huguenin, Anne-Laure; Schürch, Christian M; Banz Wälti, Yara; Sengupta, Saumitra; Aguet, Michel; Rigotti, Stefania; Bachhav, Yogeshwar; Massière, Frédéric; Ramachandra, Murali; McAllister, Andres; Riether, Carsten (2017). The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34+ Stem/Progenitor Cells. Molecular cancer therapeutics, 16(8), pp. 1497-1510. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-16-0889

Forse, Catherine L; Rahimi, Mahdi; Diamandis, Eleftherios P; Assarzadegan, Naziheh; Dawson, Heather; Grin, Andrea; Kennedy, Erin; O'Connor, Brenda; Messenger, David E; Riddell, Robert H; Kirsch, Richard; Karagiannis, George S (2017). HtrA3 stromal expression is correlated with tumor budding in stage II colorectal cancer. Experimental and molecular pathology, 103(1), pp. 94-100. Elsevier 10.1016/j.yexmp.2017.07.002

Jesinghaus, Moritz; Steiger, Katja; Slotta-Huspenina, Julia; Drecoll, Enken; Pfarr, Nicole; Meyer, Petra; Konukiewitz, Björn; Bettstetter, Marcus; Wieczorek, Kathrin; Ott, Katja; Feith, Markus; Langer, Rupert; Weichert, Wilko; Specht, Katja; Boxberg, Melanie (2017). Increased intraepithelial CD3+ T-lymphocytes and high PD-L1 expression on tumor cells are associated with a favorable prognosis in esophageal squamous cell carcinoma and allow prognostic immunogenic subgrouping. OncoTarget, 8(29), pp. 46756-46768. Impact Journals LLC 10.18632/oncotarget.18606

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Marti, Nesa Magdalena; Galván, José A.; Pandey, Amit Vikram; Trippel, Mafalda; Tapia, Coya; Müller, Michel; Perren, Aurel; Flück Pandey, Christa Emma (2017). Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome. Molecular and cellular endocrinology, 441, pp. 116-123. Elsevier Ireland 10.1016/j.mce.2016.07.029

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Popp, Ilinca; Del Pozzo, Luigi; Waser, Beatrice; Reubi, Jean Claude; Meyer, Philipp T; Maecke, Helmut R; Gourni, Eleni (2017). Approaches to improve metabolic stability of a statine-based GRP receptor antagonist. Nuclear medicine and biology, 45, pp. 22-29. Elsevier 10.1016/j.nucmedbio.2016.11.004

Marinoni, Ilaria; Wiederkehr, Astrid; Wiedmer, Tabea; Pantasis, Sophia; Di Domenico, Annunziata; Rasmus Möller, Frank; Vassella, Erik; Schmitt Kurrer, Anja; Perren, Aurel (2017). Hypo-methylation mediates chromosomal instability in pancreatic NET. Endocrine-related cancer, 24(3), pp. 137-146. BioScientifica Ltd. 10.1530/ERC-16-0554

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Nolte, Sarah; Zlobec, Inti; Lugli, Alessandro; Hohenberger, Werner; Croner, Roland; Merkel, Susanne; Hartmann, Arndt; Geppert, Carol I; Rau, Tilman (2017). Construction and analysis of tissue microarrays in the era of digital pathology: a pilot study targeting CDX1 and CDX2 in a colon cancer cohort of 612 patients. The journal of pathology: clinical research, 3(1), pp. 58-70. Wiley 10.1002/cjp2.62

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Banz Wälti, Yara; Tzankov, Alexandar; Dirnhofer, Stephan; Perren, Aurel; Hoeller, Sylvia (2017). Lymphadenectomy Specimens in a Large Retrospective Cohort of Pediatric Patients Reveal No in situ Lymphomas but a Broad Spectrum of Reactive Changes. Pathobiology, 84(3), pp. 139-143. Karger 10.1159/000449253

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Sendi, Parham; Hirzel, Cédric; Pfister, Stefan; Ackermann-Gäumann, Rahel; Grandgirard, Denis; Hewer, Ekkehard; Nirkko, Arto Christian (2017). Fatal Outcome of Tick-borne Encephalitis after Vaccine Failure. Frontiers in neurology, 8(119), p. 119. Frontiers Media S.A. 10.3389/fneur.2017.00119

Schürch, Christian; Forster, Stefan; Brühl, Frido; Yang, Sara Hsin-Yi; Felley-Bosco, Emanuela; Hewer, Ekkehard (2017). The “don't eat me” signal CD47 is a novel diagnostic biomarker and potential therapeutic target for diffuse malignant mesothelioma. Oncoimmunology, 7(1), e1373235. Taylor & Francis 10.1080/2162402X.2017.1373235

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Oberg, Kjell; Couvelard, Anne; Delle Fave, Gianfranco; Gross, David; Grossman, Ashley; Jensen, Robert T.; Pape, Ulrich-Frank; Perren, Aurel; Rindi, Guido; Ruszniewski, Philippe; Scoazec, Jean-Yves; Welin, Staffan; Wiedenmann, Bertram; Ferone, Diego (2017). ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Biochemical Markers. Neuroendocrinology, 105(3), pp. 201-211. Karger 10.1159/000472254

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2016

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