Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry-based metabolomics

Johnson, Caroline H; Slanař, Ondřej; Krausz, Kristopher W; Kang, Dong Wook; Patterson, Andrew D; Kim, Jung-Hwan; Luecke, Hans; Gonzalez, Frank J; Idle, Jeffrey R (2012). Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry-based metabolomics. American journal of clinical nutrition, 96(4), pp. 818-30. Bethesda, Md.: American Society for Nutrition, Inc. 10.3945/ajcn.112.042929

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Contradictory results from clinical trials that examined the role of vitamin E in chronic disease could be a consequence of interindividual variation, caused by factors such as xenobiotic use. Cometabolism of vitamin E with other pharmaceutical products could affect the bioavailability of the drug. Thus, it is necessary to understand fully the metabolic routes and biological endpoints of vitamin E.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Idle, Jeffrey

ISSN:

0002-9165

Publisher:

American Society for Nutrition, Inc.

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:38

Last Modified:

05 Dec 2022 14:11

Publisher DOI:

10.3945/ajcn.112.042929

PubMed ID:

22952181

Web of Science ID:

000308977000016

BORIS DOI:

10.48350/15226

URI:

https://boris.unibe.ch/id/eprint/15226 (FactScience: 222518)

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