Dierks, C; Mömke, S; Drögemüller, Cord; Leeb, Tosso; Chowdhary, B P; Distl, O (2006). A high-resolution comparative radiation hybrid map of equine chromosome 4q12-q22. Animal genetics, 37(5), pp. 513-7. Oxford: Blackwell 10.1111/j.1365-2052.2006.01510.x
Full text not available from this repository. (Request a copy)In this study, we present a comprehensive 5000-rad radiation hybrid map of a 40-cM region on equine chromosome 4 (ECA4) that contains quantitative trait loci for equine osteochondrosis. We mapped 29 gene-associated sequence tagged site markers using primers designed from equine expressed sequence tags or BAC clones in the ECA4q12-q22 region. Three blocks of conserved synteny, showing two chromosomal breakpoints, were identified in the segment of ECA4q12-q22. Markers from other segments of HSA7q mapped to ECA13p and ECA4p, and a region of HSA7p was homologous to ECA13p. Therefore, we have improved the resolution of the human-equine comparative map, which allows the identification of candidate genes underlying traits of interest.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) 05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Institute of Genetics |
UniBE Contributor: |
Drögemüller, Cord, Leeb, Tosso |
Subjects: |
500 Science > 590 Animals (Zoology) 600 Technology > 630 Agriculture |
ISSN: |
0268-9146 |
Publisher: |
Blackwell |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:45 |
Last Modified: |
05 Dec 2022 14:13 |
Publisher DOI: |
10.1111/j.1365-2052.2006.01510.x |
PubMed ID: |
16978184 |
Web of Science ID: |
000240565900014 |
URI: |
https://boris.unibe.ch/id/eprint/18459 (FactScience: 602) |
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