Hemodynamic Performance of Edwards Intuity Valve in a Compliant Aortic Root Model

Jahren, Silje Ekroll; Heinisch, Paul Philipp; Wirz, Jessica; Winkler, Bernhard; Carrel, Thierry; Obrist, Dominik (25 August 2015). Hemodynamic Performance of Edwards Intuity Valve in a Compliant Aortic Root Model. IEEE Engineering in Medicine and Biology Society conference proceedings, 2015, pp. 3315-3318. IEEE Service Center 10.1109/EMBC.2015.7319101

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Numerous designs of bioprosthetic valves exist. The sutureless surgical valve is a newer design concept which combines elements of the transcatheter valve technology with surgical valves. This design aims at shorter and easier implantation. It was the aim of this study to perform hemodynamic and kinematic measurements for this type of valves to serve as a baseline for following studies which investigate the effect of the aortic root on the valve performance. To this end, the Edwards Intuity aortic valve was investigated in a new in vitro flow loop mimicking the left heart. The valve was implanted in a transparent, compliant aortic root model, and the valve kinematics was investigated using a high speed camera together with synchronized hemodynamic measurements of pressures and flows. The valve closure was asynchronous (one by one leaflet), and the valve started to close before the deceleration of the fluid. The aortic root model showed a dilation of the sinuses which was different to the ascending aorta, and the annulus was found to move towards the left ventricle during diastole and towards the aorta during systole.

Item Type: Conference or Workshop Item (Paper)
Division/Institute: 10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Cardiovascular Engineering (CVE)
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research
Graduate School: Graduate School for Cellular and Biomedical Sciences (GCB)
UniBE Contributor: Jahren, Silje Ekroll; Heinisch, Paul Philipp; Winkler, Bernhard; Carrel, Thierry and Obrist, Dominik
Subjects: 500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health
600 Technology > 620 Engineering
ISSN: 1557-170X
Publisher: IEEE Service Center
Language: English
Submitter: Silje Ekroll Jahren
Date Deposited: 18 May 2015 16:40
Last Modified: 26 Jun 2016 02:02
Publisher DOI: 10.1109/EMBC.2015.7319101
PubMed ID: 26737001
Uncontrolled Keywords: Fluids; Heart; Hemodynamics; Invitro; Kinematics; Surgery; Valves
BORIS DOI: 10.7892/boris.68424
URI: http://boris.unibe.ch/id/eprint/68424

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