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Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medová, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak (2023). Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(4), p. 85. Springer 10.1007/s00018-023-04725-8
Sengupta, Arunima; Dorn, Aurélien; Jamshidi, Mohammad; Schwob, Magali; Hassan, Widad; De Maddalena, Lea Lara; Hugi, Andreas; Stucki, Andreas O.; Dorn, Patrick; Marti, Thomas M.; Wisser, Oliver; Stucki, Janick D.; Krebs, Tobias; Hobi, Nina; Guenat, Olivier T. (2023). A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Frontiers in Pharmacology, 14, p. 1114739. Frontiers 10.3389/fphar.2023.1114739
Yang, Haitang; Gao, Yanyun; Xu, Duo; Xu, Ke; Shun-Qing, Liang; Yang, Zhang; Scherz, Amina; Hall, Sean R R; Forster, Stefan; Berezowska, Sabina; Yao, Feng; Ochsenbein, Adrian F; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Dorn, Patrick; Peng, Ren-Wang (2023). MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 9(1), p. 55. Nature 10.1038/s41420-023-01307-2
Orlando, Eleonora; Medo, Matúš; Bensimon, Ariel; Quintin, Aurélie; Riedo, Rahel; Roth, Selina M; Riether, Carsten; Marti, Thomas M; Aebersold, Daniel M; Medova, Michaela; Aebersold, Ruedi; Zimmer, Yitzhak; quintin, a (2022). An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies. Cellular and molecular life sciences : CMLS, 80(1), p. 6. Springer 10.1007/s00018-022-04634-2
Xu, Duo; Liu, Shengchen; Wu, Xi; Marti, Thomas M; Dorn, Patrick; Schmid, Ralph A; Peng, Ren-Wang; Shu, Yongqian (2022). Dissecting the Immunological Profiles in NSD3-Amplified LUSC through Integrative Multi-Scale Analyses. Cancers, 14(20) MDPI AG 10.3390/cancers14204997
Karatkevich, Darya; Deng, Haibin; Gao, Yanyun; Flint, Emilio; Peng, Ren-Wang; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael (2022). Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma. International journal of molecular sciences, 23(19) MDPI 10.3390/ijms231911949
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Guler, Sabina A; Machahua, Carlos; Geiser, Thomas K; Kocher, Gregor; Marti, Thomas M; Tan, Benjamin; Trappetti, Verdiana; Ryerson, Christopher J; Funke-Chambour, Manuela (2022). Dehydroepiandrosterone in fibrotic interstitial lung disease: a translational study. Respiratory research, 23(1), p. 149. BioMed Central 10.1186/s12931-022-02076-9
Sengupta, Arunima; Roldan, Nuria; Kiener, Mirjam; Froment, Laurène; Raggi, Giulia; Imler, Theo; de Maddalena, Lea; Rapet, Aude; May, Tobias; Carius, Patrick; Schneider-Daum, Nicole; Lehr, Claus-Michael; Kruithof-de Julio, Marianna; Geiser, Thomas; Marti, Thomas; Stucki, Janick D.; Hobi, Nina; Guenat, Olivier T (2022). A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System. Frontiers in toxicology, 4(840606), pp. 1-18. Frontiers Media S.A. 10.3389/ftox.2022.840606
Zeinali, S.; Rechberger, K. F.; Dubey, C.; Gashi, R.; Marti, T.; Dorn, P.; Guenat, O. T. (April 2022). Metastasis-on-chip: 3D human microvasculature network to study extravasation dynamics of lung cancer in vitro. Annals of oncology, 33(S2), S92-S92. Elsevier 10.1016/j.annonc.2022.02.159
Yang, Haitang; Sun, Beibei; Fan, Liwen; Ma, Wenyan; Xu, Ke; Hall, Sean R R; Wang, Zhexin; Schmid, Ralph A; Peng, Ren-Wang; Marti, Thomas M; Gao, Wen; Xu, Jianlin; Yang, Weiwei; Yao, Feng (2022). Multi-scale integrative analyses identify THBS2+ cancer-associated fibroblasts as a key orchestrator promoting aggressiveness in early-stage lung adenocarcinoma. Theranostics, 12(7), pp. 3104-3130. Ivyspring International 10.7150/thno.69590
Yang, Zhang; Shun-Qing, Liang; Zhao, Liang; Yang, Haitang; Marti, Thomas M; Hegedüs, Balazs; Gao, Yanyun; Zheng, Bin; Chen, Chun; Wang, Wenxiang; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2022). Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. Journal of experimental & clinical cancer research, 41(1), p. 25. BioMed Central 10.1186/s13046-022-02240-5
Lipp, Jesse J; Wang, Limei; Yang, Haitang; Yao, Feng; Harrer, Nathalie; Müller, Stefan; Berezowska, Sabina; Dorn, Patrick; Marti, Thomas M; Schmid, Ralph A; Hegedüs, Belazs; Souabni, Abdallah; Carotta, Sebastian; Pearson, Mark A; Sommergruber, Wolfgang; Kocher, Gregor J; Hall, Sean R R (2022). Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology, 11(1), p. 2019466. Taylor & Francis 10.1080/2162402X.2021.2019466
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
Ning, Wenjuan; Marti, Thomas M; Dorn, Patrick; Peng, Ren-Wang (2022). Non-genetic adaptive resistance to KRASG12C inhibition: EMT is not the only culprit. Frontiers in oncology, 12, p. 1004669. Frontiers Research Foundation 10.3389/fonc.2022.1004669
Yang, Haitang; Berezowska, Sabina; Dorn, Patrick; Zens, Philipp; Chen, Peiru; Peng, Ren-Wang; Marti, Thomas M; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2022). Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics, 12(1), pp. 167-185. Ivyspring International 10.7150/thno.61209
Wang, Limei; Yang, Haitang; Dorn, Patrick; Berezowska, Sabina; Blank, Fabian; Wotzkow, Carlos; Marti, Thomas M; Peng, Ren-Wang; Harrer, Nathalie; Sommergruber, Wolfgang; Kocher, Gregor J; Schmid, Ralph A; Hall, Sean R R (2021). Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer. EBioMedicine, 73, p. 103664. Elsevier 10.1016/j.ebiom.2021.103664
Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193
Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789
Yang, Zhang; Liang, Shun-Qing; Yang, Haitang; Xu, Duo; Bruggmann, Rémy; Gao, Yanyun; Deng, Haibin; Berezowska, Sabina; Hall, Sean R R; Marti, Thomas M; Kocher, Gregor J; Zhou, Qinghua; Schmid, Ralph A; Peng, Ren-Wang (2021). CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer. Cancer research, 81(11), pp. 3121-3133. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-20-2276
Gao, Yanyun; Zens, Philipp; Su, Min; Gemperli, Camila Anna; Yang, Haitang; Deng, Haibin; Yang, Zhang; Xu, Duo; Hall, Sean R R; Berezowska, Sabina; Dorn, Patrick; Peng, Ren-Wang; Schmid, Ralph Alexander; Wang, Wenxiang; Marti, Thomas Michael (2021). Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). Journal of experimental & clinical cancer research, 40(1), pp. 1-22. BioMed Central 10.1186/s13046-021-01938-2
Xu, Duo; Liang, Shun-Qing; Yang, Zhang; Yang, Haitang; Bruggmann, Rémy; Oberhaensli, Simone; Berezowska, Sabina; Marti, Thomas M; Hall, Sean R R; Dorn, Patrick; Kocher, Gregor J; Schmid, Ralph A; Peng, Ren-Wang (2021). Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis. Cell death & disease, 12(4), p. 406. Nature Publishing Group 10.1038/s41419-021-03668-x
Yang, Haitang; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Beyond DNA Repair: DNA-PKcs in Tumor Metastasis, Metabolism and Immunity. Cancers, 12(11) MDPI AG 10.3390/cancers12113389
Yang, Haitang; Zhao, Liang; Gao, Yanyun; Yao, Feng; Marti, Thomas M.; Schmid, Ralph A.; Peng, Ren-Wang (2020). Pharmacotranscriptomic Analysis Reveals Novel Drugs and Gene Networks Regulating Ferroptosis in Cancer. Cancers, 12(11) MDPI AG 10.3390/cancers12113273
Wang, Limei; Dorn, Patrick; Simillion, Cedric; Froment, Laurène; Berezowska, Sabina Anna; Tschanz, Stefan A.; Haenni, Beat; Blank, Fabian; Wotzkow, Carlos; Peng, Ren-Wang; Marti, Thomas; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph; Hall, Sean (2020). EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and is associated with pathogenesis of pulmonary disease including lung adenocarcinoma. American journal of physiology - lung cellular and molecular physiology, 319(5), L794-L809. American Physiological Society 10.1152/ajplung.00279.2019
Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Bruggmann, Rémy; Berezowska, Sabina; Zhang, Yang; Marti, Thomas; Hall, Sean Ralph Robert; Gao, Yanyun; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2020). CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma. Molecular cancer therapeutics, 19(2), pp. 661-672. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-19-0724
Xu, Duo; Yang, Haitang; Zhang, Yang; Berezowska, Sabina; Gao, Yanyun; Shun-Qing, Liang; Marti, Thomas M.; Hall, Sean R. R.; Dorn, Patrick; Kocher, Gregor J.; Schmid, Ralph A.; Peng, Ren-Wang (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma. Cancers, 11(10) MDPI AG 10.3390/cancers11101502
Yang, Haitang; Shun-Qing, Liang; Xu, Duo; Zhang, Yang; Marti, Thomas M.; Gao, Yanyun; Kocher, Gregor J.; Zhao, Heng; Schmid, Ralph A.; Peng, Ren-Wang (2019). HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis, 8(9), p. 45. Springer Nature 10.1038/s41389-019-0158-7
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008
Shun-Qing, Liang; Bührer, Elias; Berezowska, Sabina Anna; Marti, Thomas; Xu, Duo; Froment, Laurène; Yang, Haitang; Hall, Sean; Vassella, Erik; Zhang, Yang; Kocher, Gregor; Amrein, Michael Alex; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Peng, Ren-Wang (2019). mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. Oncogene, 38(5), pp. 622-636. Nature Publishing Group 10.1038/s41388-018-0479-6
Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1
Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8
Xu, Duo; Shun-Qing, Liang; Yang, Haitang; Lüthi, Ursina; Riether, Carsten; Berezowska, Sabina Anna; Marti, Thomas; Hall, Sean; Bruggmann, Rémy; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2018). Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma. British journal of cancer, 119(1), pp. 65-75. Nature Publishing Group 10.1038/s41416-018-0145-3
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Hall, Sean; Froment, Laurène; Dorn, Patrick; Berezowska, Sabina Anna; Schmid, Ralph (7 May 2017). Characterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples. Annals of oncology, 28(suppl_2), ii4. Oxford University Press 10.1093/annonc/mdx090.013
Berezowska, Sabina Anna; Galván Hernández, José Alberto; Langer, Rupert; Bubendorf, Lukas; Savic, Spasenija; Gugger, Mathias; Schmid, Ralph; Marti, Thomas (2017). Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer. Virchows Archiv, 470(3), pp. 323-330. Springer 10.1007/s00428-016-2057-z
Ebener, Simone; Barnowski, Sandra; Wotzkow Alvarez, Carlos; Marti, Thomas; Lopez-Rodriguez, Elena; Crestani, Bruno; Blank, Fabian; Schmid, Ralph; Geiser, Thomas; Funke, Manuela (2017). Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF. American journal of physiology - lung cellular and molecular physiology, 312(1), L42-L55. American Physiological Society 10.1152/ajplung.00119.2016
Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 10PD Assessment of PD-L1 and CD47 expression together with tumor-associated TILs in resectable early stage NSCLC. Annals of oncology, 27(suppl_8), viii3. Oxford University Press 10.1093/annonc/mdw525.09
Hall, Sean; Wang, Limei; Marti, Thomas; Peng, Ren-Wang; Froment, Laurène; Berezowska, Sabina Anna; Kocher, Gregor; Dorn, Patrick; Schmid, Ralph (2016). 98O: Characterization of tumor infiltrating lymphocytes in resectable early stage non-small cell lung cancer. Journal of thoracic oncology, 11(4Suppl), S99-S99. Elsevier 10.1016/S1556-0864(16)30211-8
Marti, Thomas; Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph (2016). 23P Prolonged pemetrexed pretreatment increases efficiency of ionizing radiation combination therapy and correlates with the persistence of treatment-induced DNA damage in lung cancer cells. Journal of thoracic oncology, 11(4Suppl), S65-S65. Elsevier 10.1016/S1556-0864(16)30137-X
Marti, Thomas; Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph (2016). 22P Increased schedule-dependent efficiency of pemetrexed-cisplatin combination therapy eliminates resistant lung cancer stem-like cells associated with EMT. Journal of thoracic oncology, 11(4Suppl), S64-S65. Elsevier 10.1016/S1556-0864(16)30136-8
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Ren-Wang (2016). 18P Epithelial-to-mesenchymal transition (EMT) is required for resistance to anti-folate chemotherapy in lung cancer. Journal of thoracic oncology, 11(4Suppl), S63-S63. Elsevier 10.1016/S1556-0864(16)30132-0
Tièche, Colin; Peng, Ren-Wang; Dorn, Patrick; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT. BMC cancer, 16(125), p. 125. BioMed Central 10.1186/s12885-016-2117-4
Dorn, Patrick; Tièche, Colin; Peng, Ren-Wang; Froment, Laurène; Schmid, Ralph; Marti, Thomas (2016). Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells. Cancer cell international, 16(66), p. 66. BioMed Central 10.1186/s12935-016-0346-x
Shun-Qing, Liang; Marti, Thomas; Dorn, Patrick; Froment, Laurène; Hall, Sean; Berezowska, Sabina Anna; Kocher, Gregor; Schmid, Ralph; Peng, Renwang (2015). Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer. Cell death & disease, 6(e1824), e1824. Nature Publishing Group 10.1038/cddis.2015.195
Kotov, Ilya N; Siebring-van Olst, Ellen; Knobel, Philip A; van der Meulen-Muileman, Ida H; Felley-Bosco, Emanuela; van Beusechem, Victor W; Smit, Egbert F; Stahel, Rolf A; Marti, Thomas (2014). Whole genome RNAi screens reveal a critical role of REV3 in coping with replication stress. Molecular oncology, 8(8), pp. 1747-1759. Elsevier 10.1016/j.molonc.2014.07.008
Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j
