Schmitz, Andrea

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2014

Dettwiler, Ramona; Schmitz, Andrea; Plattet, Philippe; Zielinski, Jana; Mevissen, Meike (2014). Heterologous expression of equine CYP3A94 and investigation of a tunable system to regulate co-expressed NADPH P450 oxidoreductase levels. PLoS ONE, 9(11), e113540. Public Library of Science 10.1371/journal.pone.0113540

Schmitz, Andrea; Zielinski, Jana; Dick, B.; Mevissen, Meike (2014). In vitro metabolism of testosterone in the horse liver and involvement of equine CYPs 3A89, 3A94 and 3A95. Journal of veterinary pharmacology and therapeutics, 37(4), pp. 338-347. Blackwell Scientific Publications 10.1111/jvp.12106

2013

Stefanski, Anja; Mevissen, Meike; Möller, A.-M.; Kühni-Boghenbor, Kathrin; Schmitz, Andrea (2013). Induction of cytochrome P450 enzymes in primary equine hepatocyte culture. Toxicology in vitro, 27(7), pp. 2023-2030. Elsevier 10.1016/j.tiv.2013.07.009

Peters, Laureen; Demmel, Steffi; Pusch, G.; Buters, J. T. M.; Thormann, W.; Zielinski, Jana; Leeb, Tosso; Mevissen, Meike; Schmitz, Andrea (2013). Equine cytochrome P450 2B6--genomic identification, expression and functional characterization with ketamine. Toxicology and Applied Pharmacology, 266(1), pp. 101-8. Elsevier 10.1016/j.taap.2012.10.028

2011

Mössner, Lone D; Schmitz, Andrea; Theurillat, Regula; Thormann, Wolfgang; Mevissen, Meike (2011). Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans. American journal of veterinary research, 72(11), pp. 1505-13. Chicago, Ill.: American Veterinary Medical Association

2010

Portmann, Simone; Kwan, Hiu Ying; Theurillat, Regula; Schmitz, Andrea; Mevissen, Meike; Thormann, Wolfgang (2010). Enantioselective capillary electrophoresis for identification and characterization of human cytochrome P450 enzymes which metabolize ketamine and norketamine in vitro. Journal of chromatography A, 1217(51), pp. 7942-8. Amsterdam: Elsevier Science 10.1016/j.chroma.2010.06.028

Schmitz, Andrea; Thormann, Wolfgang; Moessner, Lone; Theurillat, Regula; Helmja, Kati; Mevissen, Meike (2010). Enantioselective CE analysis of hepatic ketamine metabolism in different species in vitro. Electrophoresis, 31(9), pp. 1506-16. Weinheim: Wiley-VCH 10.1002/elps.200900703

Schmitz, Andrea; Demmel, Steffi; Peters, Laureen M.; Leeb, Tosso; Mevissen, Meike; Haase, Bianca (2010). Comparative human-horse sequence analysis of the CYP3A subfamily gene cluster. Animal genetics, 41, pp. 72-79. Oxford: Blackwell 10.1111/j.1365-2052.2010.02111.x

2009

Capponi, Livia; Schmitz, Andrea; Thormann, Wolfgang; Theurillat, Regula; Mevissen, Meike (2009). In vitro evaluation of differences in phase 1 metabolism of ketamine and other analgesics among humans, horses, and dogs. American journal of veterinary research, 70(6), pp. 777-86. Chicago, Ill.: American Veterinary Medical Association 10.2460/ajvr.70.6.777

2008

Schmitz, A; Portier, C J; Thormann, W; Theurillat, R; Mevissen, Meike (2008). Stereoselective biotransformation of ketamine in equine liver and lung microsomes. Journal of veterinary pharmacology and therapeutics, 31(5), pp. 446-55. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2885.2008.00972.x

2007

Theurillat, Regula; Knobloch, Monika; Schmitz, Andrea; Lassahn, Paul-Gerhard; Mevissen, Meike; Thormann, Wolfgang (2007). Enantioselective analysis of ketamine and its metabolites in equine plasma and urine by CE with multiple isomer sulfated beta-CD. Electrophoresis, 28(15), pp. 2748-2757. Weinheim: Wiley-VCH 10.1002/elps.200600820

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