Y Chromosome Uncovers the Recent Oriental Origin of Modern Stallions.

Wallner, Barbara; Palmieri, Nicola; Vogl, Claus; Rigler, Doris; Bozlak, Elif; Druml, Thomas; Jagannathan, Vidhya; Leeb, Tosso; Fries, Ruedi; Tetens, Jens; Thaller, Georg; Metzger, Julia; Distl, Ottmar; Lindgren, Gabriella; Rubin, Carl-Johan; Andersson, Leif; Schaefer, Robert; McCue, Molly; Neuditschko, Markus; Rieder, Stefan; ... (2017). Y Chromosome Uncovers the Recent Oriental Origin of Modern Stallions. Current Biology, 27(13), pp. 2029-2035. Cell Press 10.1016/j.cub.2017.05.086

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The Y chromosome directly reflects male genealogies, but the extremely low Y chromosome sequence diversity in horses has prevented the reconstruction of stallion genealogies [1, 2]. Here, we resolve the first Y chromosome genealogy of modern horses by screening 1.46 Mb of the male-specific region of the Y chromosome (MSY) in 52 horses from 21 breeds. Based on highly accurate pedigree data, we estimated the de novo mutation rate of the horse MSY and showed that various modern horse Y chromosome lineages split much later than the domestication of the species. Apart from few private northern European haplotypes, all modern horse breeds clustered together in a roughly 700-year-old haplogroup that was transmitted to Europe by the import of Oriental stallions. The Oriental horse group consisted of two major subclades: the Original Arabian lineage and the Turkoman horse lineage. We show that the English Thoroughbred MSY was derived from the Turkoman lineage and that English Thoroughbred sires are largely responsible for the predominance of this haplotype in modern horses.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Institute of Genetics
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

UniBE Contributor:

Jagannathan, Vidya and Leeb, Tosso

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 590 Animals (Zoology)
600 Technology > 630 Agriculture

ISSN:

0960-9822

Publisher:

Cell Press

Language:

English

Submitter:

Tosso Leeb

Date Deposited:

12 Oct 2017 08:27

Last Modified:

12 Oct 2017 08:34

Publisher DOI:

10.1016/j.cub.2017.05.086

PubMed ID:

28669755

Uncontrolled Keywords:

Equus caballus Y chromosome breeding genealogy haplotype horse patrilineal ancestry phylogeny stallion line

BORIS DOI:

10.7892/boris.101832

URI:

https://boris.unibe.ch/id/eprint/101832

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