Portal vein thrombosis in patients with cirrhosis.

von Köckritz, Leona Isabella; De Gottardi, Andrea; Trebicka, Jonel; Praktiknjo, Michael (2017). Portal vein thrombosis in patients with cirrhosis. Gastroenterology report, 5(2), pp. 148-156. Oxford University Press 10.1093/gastro/gox014

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Portal vein thrombosis (PVT) is frequent in patients with liver cirrhosis and possible severe complications such as mesenteric ischemia are rare, but can be life-threatening. However, different aspects of clinical relevance, diagnosis and management of PVT are still areas of uncertainty and investigation in international guidelines. In this article, we elaborate on PVT classification, geographical differences in clinical presentation and standards of diagnosis, and briefly on the current pathophysiological understanding and risk factors. This review considers and highlights the pitfalls of the various treatment approaches and prophylactic treatments. Finally, we review the controversial issue of clinical impact of PVT on prognosis, especially considering liver transplantation and future perspectives.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine

UniBE Contributor:

von Köckritz, Leona Isabella and De Gottardi, Andrea

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2052-0034

Publisher:

Oxford University Press

Language:

English

Submitter:

Thi Thao Anh Pham

Date Deposited:

22 Nov 2017 10:17

Last Modified:

22 Nov 2017 10:17

Publisher DOI:

10.1093/gastro/gox014

PubMed ID:

28533912

Uncontrolled Keywords:

liver cirrhosis liver transplantation low-molecular-weight heparin portal vein thrombosis thrombophilia tests transjugular intrahepatic portosystemic shunt

BORIS DOI:

10.7892/boris.106376

URI:

https://boris.unibe.ch/id/eprint/106376

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