Other Extrahepatic Manifestations of Hepatitis C Virus Infection (Pulmonary, Idiopathic Thrombocytopenic Purpura, Nondiabetes Endocrine Disorders).

Segna, Daniel; Dufour, Jean-François (2017). Other Extrahepatic Manifestations of Hepatitis C Virus Infection (Pulmonary, Idiopathic Thrombocytopenic Purpura, Nondiabetes Endocrine Disorders). Clinics in Liver Disease, 21(3), pp. 607-629. Elsevier 10.1016/j.cld.2017.03.014

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Extrahepatic manifestations of hepatitis C virus (HCV) infection are a rare but serious condition. This article summarizes the current literature on the association between HCV and endocrine and pulmonary manifestations, as well as idiopathic thrombocytopenic purpura (ITP). HCV may directly infect extrahepatic tissues and interact with the immune system predisposing for obstructive and interstitial lung disease, ITP, autoimmune thyroiditis, infertility, growth hormone and adrenal deficiencies, osteoporosis, and potentially lung and thyroid cancers. However, in many cases, the current evidence is divergent and cannot sufficiently confirm a true association, which emphasizes the need for future targeted projects in this field.

Item Type:	Journal Article (Review Article)
Division/Institute:	04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine 04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine
UniBE Contributor:	Segna, Daniel, Dufour, Jean-François
Subjects:	600 Technology > 610 Medicine & health
ISSN:	1089-3261
Publisher:	Elsevier
Language:	English
Submitter:	Thi Thao Anh Pham
Date Deposited:	01 Feb 2018 11:31
Last Modified:	05 Dec 2022 15:08
Publisher DOI:	10.1016/j.cld.2017.03.014
PubMed ID:	28689597
Uncontrolled Keywords:	Endocrine Extrahepatic manifestations Hepatitis C Idiopathic thrombocytopenic purpura Pulmonary
URI:	https://boris.unibe.ch/id/eprint/107124