The Expanding Field of Mammalian Astroviruses: Opportunities and Challenges in Clinical Virology.

Boujon, Céline; Koch, Michel Christoph; Seuberlich, Torsten (2017). The Expanding Field of Mammalian Astroviruses: Opportunities and Challenges in Clinical Virology. Advances in virus research, 99, pp. 109-137. Elsevier 10.1016/bs.aivir.2017.07.002

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Astroviruses are best known as being one of the leading causes of diarrhea in infants and were first described in this context in 1975. In its first years, astrovirus research was mainly restricted to electron microscopy and serology studies. The ability to culture some of these viruses in vitro allowed a first consequent step forward, especially at the molecular level. Since the emergence of more powerful genetic methods, though, the face of this research field has dramatically changed and evolved. From the exponential number of discoveries of new astrovirus strains in the most varied of animal species to their association with atypical diseases, these viruses revealed a lot of surprises, and many more are probably still waiting to be uncovered. This chapter summarizes the most important knowledge about astroviruses and discusses the implication of the latest findings in this area of research.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > NeuroCenter
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Experimental Clinical Research
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Boujon, Céline; Koch, Michel Christoph and Seuberlich, Torsten

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 630 Agriculture

ISSN:

1557-8399

Publisher:

Elsevier

Language:

English

Submitter:

Céline Boujon

Date Deposited:

01 May 2018 11:15

Last Modified:

25 Oct 2019 05:34

Publisher DOI:

10.1016/bs.aivir.2017.07.002

PubMed ID:

29029723

Uncontrolled Keywords:

Astrovirus Causality Clinical virology Evolution Gastroenteritis Metagenomics Neurology

BORIS DOI:

10.7892/boris.109016

URI:

https://boris.unibe.ch/id/eprint/109016

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