Automated low-flow ascites pump for the treatment of cirrhotic patients with refractory ascites.

Stirnimann, Guido; Banz Wüthrich, Vanessa; Storni, Federico Lorenzo; De Gottardi, Andrea (2017). Automated low-flow ascites pump for the treatment of cirrhotic patients with refractory ascites. Therapeutic advances in gastroenterology, 10(2), pp. 283-292. Sage 10.1177/1756283X16684688

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Cirrhotic patients with refractory ascites (RA) can be treated with repeated large volume paracentesis (LVP), with the insertion of a transjugular intrahepatic portosystemic shunt (TIPS) or with liver transplantation. However, side effects and complications of these therapeutic options, as well as organ shortage, warrant the development of novel treatments. The automated low-flow ascites pump (alfapump®) is a subcutaneously-implanted novel battery-driven device that pumps ascitic fluid from the peritoneal cavity into the urinary bladder. Ascites can therefore be aspirated in a time- and volume-controlled mode and evacuated by urination. Here we review the currently available data about patient selection, efficacy and safety of the alfapump and provide recommendations for the management of patients treated with this new method.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Viszeralchirurgie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Viszeralchirurgie

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

UniBE Contributor:

Stirnimann, Guido; Banz Wüthrich, Vanessa; Storni, Federico Lorenzo and De Gottardi, Andrea

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1756-283X

Publisher:

Sage

Language:

English

Submitter:

Lilian Karin Smith-Wirth

Date Deposited:

05 Mar 2018 11:05

Last Modified:

05 Mar 2018 11:05

Publisher DOI:

10.1177/1756283X16684688

PubMed ID:

28203285

Uncontrolled Keywords:

albumin cirrhosis decompensation diuretics spontaneous bacterial peritonitis

BORIS DOI:

10.7892/boris.109044

URI:

https://boris.unibe.ch/id/eprint/109044

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