Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO).

Soffietti, Riccardo; Abacioglu, Ufuk; Baumert, Brigitta; Combs, Stephanie E; Kinhult, Sara; Kros, Johan M; Marosi, Christine; Metellus, Philippe; Radbruch, Alexander; Villa Freixa, Salvador S; Brada, Michael; Carapella, Carmine M; Preusser, Matthias; Le Rhun, Emilie; Rudà, Roberta; Tonn, Joerg C; Weber, Damien Charles; Weller, Michael (2017). Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO). Neuro-Oncology, 19(2), pp. 162-174. Oxford University Press 10.1093/neuonc/now241

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The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy (with particular attention to brain metastases from non-small cell lung cancer, melanoma and breast and renal cancer), and supportive care.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology

UniBE Contributor:

Weber, Damien Charles

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1523-5866

Publisher:

Oxford University Press

Language:

English

Submitter:

Beatrice Scheidegger

Date Deposited:

06 Mar 2018 14:05

Last Modified:

22 Oct 2019 22:55

Publisher DOI:

10.1093/neuonc/now241

PubMed ID:

28391295

Uncontrolled Keywords:

brain metastases chemotherapy neuroimaging neuropathology stereotactic radiosurgery/stereotactic fractionated radiotherapy supportive care surgery targeted therapy whole-brain radiation therapy

BORIS DOI:

10.7892/boris.109300

URI:

https://boris.unibe.ch/id/eprint/109300

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