Berzigotti, Annalisa (2017). Non-invasive evaluation of portal hypertension using ultrasound elastography. Journal of hepatology, 67(2), pp. 399-411. Elsevier 10.1016/j.jhep.2017.02.003
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Portal hypertension (PH) leads to serious complications, such as bleeding from gastroesophageal varices, ascites and portosystemic encephalopathy in patients with chronic liver disease (CLD). Gold standard methods for assessing PH and its complications include the measurement of hepatic venous pressure gradient and endoscopy; however, these are invasive, expensive and not available at all centres. Therefore, non-invasive alternatives have been the subject of extensive investigation over the last 20years. The present review focuses on the role of ultrasound elastography - a novel group of non-invasive techniques used to measure stiffness in target organs. In the context of CLD these methods are used to identify the presence of PH, its severity, and the risk of PH-related complications. The rationale, accumulated evidence, advantages and limitations of liver and spleen stiffness measurements evaluated by different ultrasound elastography techniques in patients with advanced CLD is discussed. Recent data regarding the use of ultrasound elastography techniques in patients with non-cirrhotic forms of PH are also described.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology |
UniBE Contributor: |
Berzigotti, Annalisa |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0168-8278 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Thi Thao Anh Pham |
Date Deposited: |
30 Jan 2018 15:18 |
Last Modified: |
05 Dec 2022 15:09 |
Publisher DOI: |
10.1016/j.jhep.2017.02.003 |
PubMed ID: |
28223101 |
Uncontrolled Keywords: |
Advanced chronic liver disease Cirrhosis Decompensation Non-invasive Varices |
BORIS DOI: |
10.7892/boris.109578 |
URI: |
https://boris.unibe.ch/id/eprint/109578 |