Harnessing Nanoparticles for Immunomodulation and Vaccines.

Gomes, Ariane C; Mohsen, Mona; Bachmann, Martin (2017). Harnessing Nanoparticles for Immunomodulation and Vaccines. Vaccines, 5(1) MDPI 10.3390/vaccines5010006

[img]
Preview
Text
vaccines-05-00006.pdf - Published Version
Available under License Creative Commons: Attribution (CC-BY).

Download (1MB) | Preview

The first successful use of nanoparticles (NPs) for vaccination was reported almost 40 years ago with a virus-like particle-based vaccine against Hepatitis B. Since then, the term NP has been expanded to accommodate a large number of novel nano-sized particles engineered from a range of materials. The great interest in NPs is likely not only a result of the two successful vaccines against hepatitis B and Human Papilloma Virus (HPV) that use this technology, but also due to the versatility of those small-sized particles, as indicated by the wide range of applications reported so far, ranging from medicinal and cosmetics to purely technical applications. In this review, we will focus on the use of NPs, especially virus-like particles (VLPs), in the field of vaccines and will discuss their employment as vaccines, antigen display platforms, adjuvants and drug delivery systems.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie

UniBE Contributor:

Mohsen, Mona and Bachmann, Martin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2076-393X

Publisher:

MDPI

Language:

English

Submitter:

Eveline Messerli

Date Deposited:

13 Mar 2018 11:25

Last Modified:

27 Oct 2019 08:59

Publisher DOI:

10.3390/vaccines5010006

PubMed ID:

28216554

Uncontrolled Keywords:

immunogen nanoparticles vaccines virus-like particles

BORIS DOI:

10.7892/boris.110613

URI:

https://boris.unibe.ch/id/eprint/110613

Actions (login required)

Edit item Edit item
Provide Feedback