Mohsen, Mona Omar Mahmoud

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2024

Josi, Romano; Speiser, Daniel E; de Brot, Simone; Vogt, Anne-Cathrine; Sevick-Muraca, Eva M; Tolstonog, Genrich V; Bachmann, Martin F; Mohsen, Mona O (2024). A tetravalent nanovaccine that inhibits growth of HPV-associated head and neck carcinoma via dendritic and T cell activation. iScience, 27(4) Elsevier 10.1016/j.isci.2024.109439

2023

Sobczak, Jan M; Krenger, Pascal S; Storni, Federico; Mohsen, Mona O; Balke, Ina; Reseviča, Gunta; Heath, Matthew D; Carreno Velazquez, Thalia L; Kramer, Matthias F; Scott, Callum J W; Skinner, Murray A; Zeltiņš, Andris; Kündig, Thomas M; Vogel, Monique; Bachmann, Martin F (2023). The next generation virus-like particle platform for the treatment of peanut allergy. Allergy, 78(7), pp. 1980-1996. Wiley-Blackwell 10.1111/all.15704

Vogt, Anne-Cathrine S; Jennings, Gary T; Mohsen, Mona O; Vogel, Monique; Bachmann, Martin F (2023). Alzheimer's Disease: A Brief History of Immunotherapies Targeting Amyloid β. International journal of molecular sciences, 24(4) MDPI 10.3390/ijms24043895

Chang, Xinyue; Liu, Xuelan; Martina, Byron; Zeltins, Andris; Augusto, Gilles; Vogel, Monique; Mohsen, Mona O; Speiser, Daniel E; Bachmann, Martin F (2023). Vaccination using mutated receptor binding domains of SARS-CoV-2: Evidence for partial immune escape but not serotype formation. Frontiers in immunology, 14(1114396), p. 1114396. Frontiers Research Foundation 10.3389/fimmu.2023.1114396

2022

Fernandes, Queenie; Inchakalody, Varghese Philipose; Merhi, Maysaloun; Mestiri, Sarra; Taib, Nassiba; Moustafa Abo El-Ella, Dina; Bedhiafi, Takwa; Raza, Afsheen; Al-Zaidan, Lobna; Mohsen, Mona O; Yousuf Al-Nesf, Mariam Ali; Hssain, Ali Ait; Yassine, Hadi Mohamad; Bachmann, Martin F; Uddin, Shahab; Dermime, Said (2022). Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines. Annals of medicine, 54(1), pp. 524-540. Taylor & Francis 10.1080/07853890.2022.2031274

Mohsen, Mona O; Bachmann, Martin F (2022). Virus-like particle vaccinology, from bench to bedside. Cellular & molecular immunology, 19(9), pp. 993-1011. Nature Publ. Group 10.1038/s41423-022-00897-8

Mohsen, Mona O; Heath, Matthew; Kramer, Matthias F; Velazquez, Thalia Carreno; Bullimore, Alan; Skinner, Murray A; Speiser, Daniel E; Bachmann, Martin F (2022). In situ delivery of nanoparticles formulated with micron-sized crystals protects from murine melanoma. Journal for immunotherapy of cancer, 10(9) BioMed Central 10.1136/jitc-2022-004643

Rothen, Dominik A; Krenger, Pascal S; Nonic, Aleksandra; Balke, Ina; Vogt, Anne-Cathrine S; Chang, Xinyue; Manenti, Alessandro; Vedovi, Fabio; Resevica, Gunta; Walton, Senta M; Zeltins, Andris; Montomoli, Emanuele; Vogel, Monique; Bachmann, Martin F; Mohsen, Mona O (2022). Intranasal administration of a VLP-based vaccine induces neutralizing antibodies against SARS-CoV-2 and variants of concern. Allergy, 77(8), pp. 2446-2458. Wiley 10.1111/all.15311

Vogt, Anne-Cathrine S; Jörg, Lukas; Martina, Byron; Krenger, Pascal S; Chang, Xinyue; Zeltins, Andris; Vogel, Monique; Mohsen, Mona O; Bachmann, Martin F (2022). Virus-Like Particles Are Efficient Tools for Boosting mRNA-Induced Antibodies. Frontiers in immunology, 13, p. 864718. Frontiers Research Foundation 10.3389/fimmu.2022.864718

Bachmann, Martin F; Mohsen, Mona O; Speiser, Daniel E (2022). Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism. NPJ vaccines, 7(1), p. 56. Springer Nature 10.1038/s41541-022-00479-9

Vogt, Anne-Cathrine S; Augusto, Gilles; Martina, Byron; Chang, Xinyue; Nasrallah, Gheyath; Speiser, Daniel E; Vogel, Monique; Bachmann, Martin F; Mohsen, Mona O (2022). Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron. Vaccines, 10(5) MDPI 10.3390/vaccines10050743

Bachmann, Martin F; Mohsen, Mona O; Speiser, Daniel E (2022). The Future of SARS-CoV-2 Vaccination. The New England journal of medicine, 386(9), pp. 899-900. Massachusetts Medical Society 10.1056/NEJMc2119437

Chang, Xinyue; Liu, Xuelan; Mohsen, Mona O; Zeltins, Andris; Martina, Byron; Vogel, Monique; Bachmann, Martin F (2022). Induction of Broadly Cross-Reactive Antibodies by Displaying Receptor Binding Domains of SARS-CoV-2 on Virus-like Particles. Vaccines, 10(2) MDPI 10.3390/vaccines10020307

Chang, Xinyue; Krenger, Pascal; Krüger, Caroline C; Zha, Lisha; Han, Jiami; Yermanos, Alexander; Roongta, Salony; Mohsen, Mona O; Oxenius, Annette; Vogel, Monique; Bachmann, Martin F (2022). TLR7 Signaling Shapes and Maintains Antibody Diversity Upon Virus-Like Particle Immunization. Frontiers in immunology, 12, p. 827256. Frontiers Research Foundation 10.3389/fimmu.2021.827256

Mohsen, Mona O.; Balke, Ina; Zinkhan, Simon; Zeltina, Villija; Liu, Xuelan; Chang, Xinyue; Krenger, Pascal S.; Plattner, Kevin; Gharailoo, Zahra; Vogt, Anne-Cathrine S.; Augusto, Gilles; Zwicker, Marianne; Roongta, Salony; Rothen, Dominik A.; Josi, Romano; J. Da Costa, Joana; Sobczak, Jan M.; Nonic, Aleksandra; Brand, Lee-Anne; Nuss, Katja; ... (2022). A scalable and highly immunogenic virus-like particle-based vaccine against SARS-CoV-2. Allergy, 77(1), pp. 243-257. Wiley 10.1111/all.15080

Vogel, Monique; Augusto, Gilles; Chang, Xinyue; Liu, Xuelan; Speiser, Daniel; Mohsen, Mona O.; Bachmann, Martin F. (2022). Molecular definition of severe acute respiratory syndrome coronavirus 2 receptor-binding domain mutations: Receptor affinity versus neutralization of receptor interaction. Allergy, 77(1), pp. 143-149. Wiley 10.1111/all.15002

Augusto, Gilles; Mohsen, Mona O.; Zinkhan, Simon; Liu, Xuelan; Vogel, Monique; Bachmann, Martin F. (2022). In vitro data suggest that Indian delta variant B.1.617 of SARS-CoV-2 escapes neutralization by both receptor affinity and immune evasion. Allergy, 77(1), pp. 111-117. Wiley 10.1111/all.15065

Mohsen, Mona O; Speiser, Daniel E; Michaux, Justine; Pak, HuiSong; Stevenson, Brian J; Vogel, Monique; Inchakalody, Varghese Philipose; De Brot, Simone; Dermime, Said; Coukos, Georges; Bassani-Sternberg, Michal; Bachmann, Martin F (2022). Bedside formulation of a personalized multi-neoantigen vaccine against mammary carcinoma. Journal for immunotherapy of cancer, 10(1) BMJ Publishing Group 10.1136/jitc-2021-002927

2021

Vogt, Anne-Cathrine S.; Roesti, Elisa S.; Mohsen, Mona O.; Leonchiks, Ainars; Vogel, Monique; Bachmann, Martin F. (2021). Anti-IAPP Monoclonal Antibody Improves Clinical Symptoms in a Mouse Model of Type 2 Diabetes. Vaccines, 9(11) MDPI 10.3390/vaccines9111316

Chang, Xinyue; Zeltins, Andris; Mohsen, Mona O.; Gharailoo, Zahra; Zha, Lisha; Liu, Xuelan; Walton, Senta; Vogel, Monique; Bachmann, Martin F. (2021). A Novel Double Mosaic Virus-like Particle-Based Vaccine against SARS-CoV-2 Incorporates Both Receptor Binding Motif (RBM) and Fusion Domain. Vaccines, 9(11) MDPI 10.3390/vaccines9111287

Chang, Xinyue; Sousa Augusto, Gilles; Liu, Xuelan; Kündig, Thomas M; Vogel, Monique; Mohsen, Mona O; Bachmann, Martin (2021). BNT162b2 mRNA COVID-19 vaccine induces antibodies of broader cross-reactivity than natural infection, but recognition of mutant viruses is up to 10-fold reduced. Allergy, 76(9), pp. 2895-2998. Wiley 10.1111/all.14893

Mohsen, Mona O.; Rothen, Dominik; Balke, Ina; Martina, Byron; Zeltina, Vilija; Inchakalody, Varghese; Gharailoo, Zahra; Nasrallah, Gheyath; Dermime, Said; Tars, Kaspars; Vogel, Monique; Zeltins, Andris; Bachmann, Martin F. (2021). Neutralization of MERS coronavirus through a scalable nanoparticle vaccine. NPJ vaccines, 6(1), p. 107. Springer Nature 10.1038/s41541-021-00365-w

Peterhoff, David; Thalhauser, Stefanie; Sobczak, Jan M.; Mohsen, Mona O.; Voigt, Christoph; Seifert, Nicole; Neckermann, Patrick; Hauser, Alexandra; Ding, Song; Sattentau, Quentin; Bachmann, Martin F.; Breunig, Miriam; Wagner, Ralf (2021). Augmenting the Immune Response against a Stabilized HIV-1 Clade C Envelope Trimer by Silica Nanoparticle Delivery. Vaccines, 9(6) MDPI 10.3390/vaccines9060642

Vogt, Anne-Cathrine S.; Arsiwala, Tasneem; Mohsen, Mona; Vogel, Monique; Manolova, Vania; Bachmann, Martin F. (2021). On Iron Metabolism and Its Regulation. International journal of molecular sciences, 22(9) MDPI 10.3390/ijms22094591

Liu, Xuelan; Chang, Xinyue; Rothen, Dominik; Derveni, Mariliza; Krenger, Pascal; Roongta, Salony; Wright, Edward; Vogel, Monique; Tars, Kaspars; Mohsen, Mona O.; Bachmann, Martin F. (2021). AP205 VLPs Based on Dimerized Capsid Proteins Accommodate RBM Domain of SARS-CoV-2 and Serve as an Attractive Vaccine Candidate. Vaccines, 9(4) MDPI 10.3390/vaccines9040403

Zha, Lisha; Chang, Xinyue; Zhao, Hongxin; Mohsen, Mona O.; Hong, Liang; Zhou, Yuhang; Chen, Hongquan; Liu, Xuelan; Zhang, Jie; Li, Dong; Wu, Ke; Martina, Byron; Wang, Junfeng; Vogel, Monique; Bachmann, Martin F. (2021). Development of a Vaccine against SARS-CoV-2 Based on the Receptor-Binding Domain Displayed on Virus-Like Particles. Vaccines, 9(4) MDPI 10.3390/vaccines9040395

Bachmann, Martin F.; Mohsen, Mona O.; Zha, Lisha; Vogel, Monique; Speiser, Daniel E. (2021). SARS-CoV-2 structural features may explain limited neutralizing-antibody responses. NPJ vaccines, 6(1), p. 2. Springer Nature 10.1038/s41541-020-00264-6

Zinkhan, Simon; Ogrina, Anete; Balke, Ina; Reseviča, Gunta; Zeltins, Andris; de Brot, Simone; Lipp, Cyrill; Chang, Xinyue; Zha, Lisha; Vogel, Monique; Bachmann, Martin F.; Mohsen, Mona O. (2021). The impact of size on particle drainage dynamics and antibody response. Journal of controlled release, 331, pp. 296-308. Elsevier 10.1016/j.jconrel.2021.01.012

2020

Heath, Matthew D; Mohsen, Mona O; de Kam, Pieter-Jan; Carreno Velazquez, Thalia L; Hewings, Simon J; Kramer, Matthias F; Kündig, Thomas M; Bachmann, Martin F; Skinner, Murray A (2020). Shaping Modern Vaccines: Adjuvant Systems Using MicroCrystalline Tyrosine (MCT®). Frontiers in immunology, 11, p. 594911. Frontiers Research Foundation 10.3389/fimmu.2020.594911

Mohsen, Mona O.; Augusto, Gilles; Bachmann, Martin F. (2020). The 3Ds in virus-like particle based-vaccines: "Design, Delivery and Dynamics". Immunological reviews, 296(1), pp. 155-168. Wiley-Blackwell 10.1111/imr.12863

Gilfillan, Connie B; Wang, Chensu; Mohsen, Mona O.; Rufer, Nathalie; Hebeisen, Michael; Allard, Mathilde; Verdeil, Grégory; Irvine, Darrell J; Bachmann, Martin F.; Speiser, Daniel E (2020). Murine CD8 T-cell functional avidity is stable in vivo but not in vitro: Independence from homologous prime/boost time interval and antigen density. European journal of immunology, 50(4), pp. 505-514. Wiley-VCH 10.1002/eji.201948355

Bachmann, Martin F.; Mohsen, Mona O.; Kramer, Matthias F; Heath, Matthew D (2020). Vaccination against Allergy: A Paradigm Shift? Trends in molecular medicine, 26(4), pp. 357-368. Cell Press 10.1016/j.molmed.2020.01.007

Cabral-Miranda, Gustavo; Lim, Stephanie M.; Mohsen, Mona O.; Pobelov, Ilya V.; Roesti, Elisa S.; Heath, Matthew D.; Skinner, Murray A.; Kramer, Matthias F.; Martina, Byron E. E.; Bachmann, Martin F. (2020). Correction: Zika Virus-Derived E-DIII Protein Displayed on Immunologically Optimized VLPs Induces Neutralizing Antibodies without Causing Enhancement of Dengue Virus Infection. Vaccines 2019, 7, 72. Vaccines, 8(1) MDPI 10.3390/vaccines8010094

Mohsen, Mona O.; Speiser, Daniel E; Knuth, Alexander; Bachmann, Martin F. (2020). Virus-like particles for vaccination against cancer. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 12(1), e1579. Wiley 10.1002/wnan.1579

2019

Cabral-Miranda, Gustavo; Lim, Stephanie M; Mohsen, Mona O.; Pobelov, Ilya V.; Rösti, Elisa S.; Heath, Matthew D; Skinner, Murray A; Kramer, Matthias F; Martina, Byron E E; Bachmann, Martin F. (2019). Zika Virus-Derived E-DIII Protein Displayed on Immunologically Optimized VLPs Induces Neutralizing Antibodies without Causing Enhancement of Dengue Virus Infection. Vaccines, 7(3), p. 72. MDPI 10.3390/vaccines7030072

Mohsen, Mona O.; Heath, Matthew D; Cabral-Miranda, Gustavo; Lipp, Cyrill; Zeltins, Andris; Sande, Marcos; Stein, Jens V.; Riether, Carsten; Rösti, Elisa; Zha, Lisha; Engeroff, Paul; El-Turabi, Aadil; Kundig, Thomas M; Vogel, Monique; Skinner, Murray A; Speiser, Daniel E; Knuth, Alexander; Kramer, Matthias F; Bachmann, Martin F. (2019). Correction to: Vaccination with nanoparticles combined with micro-adjuvants protects against cancer. Journal for immunotherapy of cancer, 7(1), p. 137. BioMed Central 10.1186/s40425-019-0616-y

Mohsen, Mona O.; Heath, Matthew D; Cabral-Miranda, Gustavo; Lipp, Cyrill; Zeltins, Andris; Sande, Marcos; Stein, Jens V.; Riether, Carsten; Rösti, Elisa; Zha, Lisha; Engeroff, Paul; El-Turabi, Aadil; Kundig, Thomas M; Vogel, Monique; Skinner, Murray A; Speiser, Daniel E; Knuth, Alexander; Kramer, Matthias F; Bachmann, Martin F. (2019). Vaccination with nanoparticles combined with micro-adjuvants protects against cancer. Journal for immunotherapy of cancer, 7(1), p. 114. BioMed Central 10.1186/s40425-019-0587-z

Mohsen, Mona O.; Vogel, Monique; Riether, Carsten; Muller, Julius; Salatino, Silvia; Ternette, Nicola; Gomes, Ariane C; Cabral-Miranda, Gustavo; El-Turabi, Aadil; Ruedl, Christiane; Kundig, Thomas M; Dermime, Said; Knuth, Alexander; Speiser, Daniel E; Bachmann, Martin F. (2019). Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine. Frontiers in immunology, 10, p. 1015. Frontiers Research Foundation 10.3389/fimmu.2019.01015

2018

Cabral de Miranda, Gustavo; M Salman, Ahmed; Mohsen, Mona Omar Mahmoud; Storni, Federico Lorenzo; Rösti, Elisa Simona; A Skinner, Murray; D Heath, Matthew; F Kramer, Matthias; M Khan, Shahid; J Janse, Chris; V S Hill, Adrian; Bachmann, Martin (2018). DOPS Adjuvant Confers Enhanced Protection against Malaria for VLP-TRAP Based Vaccines. Diseases, 6(4) MDPI 10.3390/diseases6040107

Zha, Lisha; De Souza Leoratti, Fabiana Maria; He, Lichun; Mohsen, Mona Omar Mahmoud; Cragg, Mark; Storni, Federico Lorenzo; Vogel, Monique; Bachmann, Martin (2018). An unexpected protective role of low-affinity allergen-specific IgG through the inhibitory receptor FcγRIIb. The Journal of allergy and clinical immunology, 142(5), 1529-1536.e6. Elsevier 10.1016/j.jaci.2017.09.054

Mohsen, Mona Omar Mahmoud; Gomes, Ariane C; Vogel, Monique; Bachmann, Martin (2018). Interaction of Viral Capsid-Derived Virus-Like Particles (VLPs) with the Innate Immune System. Vaccines, 6(3) MDPI 10.3390/vaccines6030037

2017

Mohsen, Mona; Zha, Lisha; Cabral-Miranda, Gustavo; Bachmann, Martin (2017). Major findings and recent advances in virus-like particle (VLP)-based vaccines. Seminars in immunology, 34, pp. 123-132. W.B. Saunders 10.1016/j.smim.2017.08.014

Cabral-Miranda, Gustavo; Heath, Matthew D; Gomes, Ariane C; Mohsen, Mona; Montoya-Diaz, Eduardo; Salman, Ahmed M; Atcheson, Erwan; Skinner, Murray A; Kramer, Matthias F; Reyes-Sandoval, Arturo; Bachmann, Martin (2017). Microcrystalline Tyrosine (MCT®): A Depot Adjuvant in Licensed Allergy Immunotherapy Offers New Opportunities in Malaria. Vaccines, 5(4) MDPI 10.3390/vaccines5040032

Gomes, Ariane C; Mohsen, Mona; Bachmann, Martin (2017). Harnessing Nanoparticles for Immunomodulation and Vaccines. Vaccines, 5(1) MDPI 10.3390/vaccines5010006

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