Imaging biomarkers in liver fibrosis.

Berzigotti, Annalisa; França, M; Martí-Aguado, D; Martí-Bonmatí, L (2018). Imaging biomarkers in liver fibrosis. Radiología, 60(1), pp. 74-84. Elsevier Doyma 10.1016/j.rx.2017.09.003

Text 1-s2.0-S0033833817301480-main.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (2MB)

There is a need for early identification of patients with chronic liver diseases due to their increasing prevalence and morbidity-mortality. The degree of liver fibrosis determines the prognosis and therapeutic options in this population. Liver biopsy represents the reference standard for fibrosis staging. However, given its limitations and complications, different non-invasive methods have been developed recently for the in vivo quantification of fibrosis. Due to their precision and reliability, biomarkers' measurements derived from Ultrasound and Magnetic Resonance stand out. This article reviews the different acquisition techniques and image processing methods currently used in the evaluation of liver fibrosis, focusing on their diagnostic performance, applicability and clinical value. In order to properly interpret their results in the appropriate clinical context, it seems necessary to understand the techniques and their quality parameters, the standardization and validation of the measurement units and the quality control of the methodological problems.

Interest & Impact

Downloads

1 since deposited on 19 Mar 2018
0 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item