Bilateral lingual artery stenosis: A rare, late complication of chemoradiotherapy.

Holtz, F; Monnier, Y; Borner, Urs; Nisa, Lluis (2017). Bilateral lingual artery stenosis: A rare, late complication of chemoradiotherapy. European annals of otorhinolaryngology, head and neck diseases, 134(4), pp. 269-271. Elsevier 10.1016/j.anorl.2017.02.002

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INTRODUCTION Carotid artery stenosis following radiotherapy (RT) is a known risk factor for the development of cerebrovascular disease with a risk of subsequent stroke or transient ischaemic attack. In contrast, small vessel disease in the neck following RT has been more rarely described. CASE REPORT The authors report the case of a 61-year-old man who developed partial lingual necrosis 4 years after surgery and postoperative chemoradiotherapy for squamous cell carcinoma of the floor of the mouth. Contrast-enhanced CT scan confirmed subtotal to total occlusion of both lingual arteries. Surgical debridement of the necrosis allowed complete cure of the lesions. DISCUSSION Small vessel disease is a possible complication in patients treated by RT for head and neck cancer. Although the risk of these complications is not directly related to the total radiation dose, higher doses appear to accelerate the development of vascular lesions. Practitioners must be aware of the possibility of these complications, especially in patients surviving more than 5 years.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Radio-Onkologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Radio-Onkologie

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Tumor-Immunologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Tumor-Immunologie

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)

UniBE Contributor:

Borner, Urs and Nisa, Lluis

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1879-7296

Publisher:

Elsevier

Language:

English

Submitter:

Stefan Weder

Date Deposited:

21 Feb 2018 10:29

Last Modified:

27 Oct 2019 23:34

Publisher DOI:

10.1016/j.anorl.2017.02.002

PubMed ID:

28291634

Uncontrolled Keywords:

Late complications Lingual necrosis Oral cancer Radiotherapy Vascular lesion

BORIS DOI:

10.7892/boris.110931

URI:

https://boris.unibe.ch/id/eprint/110931

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