Clinical, angiographic, IVUS, and OCT predictors for irregular protrusion after coronary stenting.

Bryniarski, Krzysztof L; Tahk, Seung-Jea; Choi, So-Yeon; Soeda, Tsunenari; Higuma, Takumi; Yamamoto, Erika; Xing, Lei; Dai, Jiannan; Zanchin, Thomas; Lee, Hang; Jang, Ik-Kyung (2017). Clinical, angiographic, IVUS, and OCT predictors for irregular protrusion after coronary stenting. EuroIntervention, 12(18), e2204-e2211. Europa Digital & Publishing 10.4244/EIJ-D-16-00679

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AIMS

Irregular protrusion identified by optical coherence tomography (OCT) immediately following stent implantation has been reported as an independent predictor for adverse cardiac events at one year. However, baseline characteristics for the development of irregular protrusion are unknown. The aim of the study was to identify predictors for irregular protrusion following stent implantation.

METHODS AND RESULTS

A total of 900 lesions in 786 patients who had post-stent OCT imaging were analysed. The patients were divided into two groups: those with (484 lesions, 456 patients) and those without (416 lesions, 330 patients) irregular protrusion. Baseline characteristics (n=786) as well as pre-stent angiogram (n=786), intravascular ultrasound (IVUS; n=31) and OCT (n=159) findings were compared between the two groups. Multivariate analysis showed that patients with irregular protrusion had higher low-density lipoprotein (LDL) cholesterol levels and lesions with greater stent length, greater percent atheroma volume on IVUS, greater lipid content and a higher prevalence of thrombus on OCT before stent implantation.

CONCLUSIONS

Irregular protrusion was found more frequently in patients with higher LDL cholesterol levels. In addition, lesions treated with longer stents, with greater plaque burden, larger lipid content and a higher prevalence of thrombus were identified as predictors for irregular protrusion following stent implantation.

Item Type:

Journal Article (Original Article)

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

ISSN:

1774-024X

Publisher:

Europa Digital & Publishing

Language:

English

Submitter:

Marlene Wolf Tobler

Date Deposited:

16 May 2018 08:23

Last Modified:

16 May 2018 08:23

Publisher DOI:

10.4244/EIJ-D-16-00679

PubMed ID:

27993755

URI:

https://boris.unibe.ch/id/eprint/112543

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