Tritschler, Manuel; Vollmann, Jutta J.; Yanez Amayo, Victor Orlando; Chejanovsky, Nor; Crailsheim, Karl; Neumann, Peter (2017). Protein nutrition governs within-host race of honey bee pathogens. Scientific Reports, 7(1), p. 14988. Nature Publishing Group 10.1038/s41598-017-15358-w
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Multiple infections are common in honey bees, Apis mellifera, but the possible role of nutrition in this regard is poorly understood. Microsporidian infections, which are promoted by protein-fed, can negatively correlate with virus infections, but the role of protein nutrition for the microsporidian-virus interface is unknown. Here, we challenged naturally deformed wing virus - B (DWV-B) infected adult honey bee workers fed with or without pollen ( = protein) in hoarding cages, with the microsporidian Nosema ceranae. Bee mortality was recorded for 14 days and N. ceranae spore loads and DWV-B titers were quantified. Amongst the groups inoculated with N. ceranae, more spores were counted in protein-fed bees. However, N. ceranae infected bees without protein-diet had reduced longevity compared to all other groups. N. ceranae infection had no effect on protein-fed bee's longevity, whereas bees supplied only with sugar-water showed reduced survival. Our data also support that protein-feeding can have a significant negative impact on virus infections in insects. The negative correlation between N. ceranae spore loads and DWV-B titers was stronger expressed in protein-fed hosts. Proteins not only enhance survival of infected hosts, but also significantly shape the microsporidian-virus interface, probably due to increased spore production and enhanced host immunity.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Institute of Bee Health 05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) |
UniBE Contributor: |
Tritschler, Manuel, Yanez Amayo, Victor Orlando, Chejanovsky, Nor, Neumann, Peter (B) |
Subjects: |
500 Science > 590 Animals (Zoology) 600 Technology > 630 Agriculture |
ISSN: |
2045-2322 |
Publisher: |
Nature Publishing Group |
Language: |
English |
Submitter: |
Anna Papach |
Date Deposited: |
22 May 2018 16:17 |
Last Modified: |
29 Mar 2023 23:35 |
Publisher DOI: |
10.1038/s41598-017-15358-w |
PubMed ID: |
29118416 |
BORIS DOI: |
10.7892/boris.113650 |
URI: |
https://boris.unibe.ch/id/eprint/113650 |
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