Measurement of 43Sc and 44Sc production cross-section with an 18 MeV medical PET cyclotron

Carzaniga, Tommaso Stefano; Auger, Martin; Braccini, Saverio; Bunka, M.; Ereditato, Antonio; Nesteruk, Konrad Pawel; Scampoli, Paola; Thürler, A.; van der Meulen, N. (2017). Measurement of 43Sc and 44Sc production cross-section with an 18 MeV medical PET cyclotron. Applied radiation and isotopes, 129, pp. 96-102. Elsevier 10.1016/j.apradiso.2017.08.013

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⁴³Sc and ⁴⁴Sc are positron emitter radionuclides that, in conjunction with the β- emitter ⁴⁷Sc, represent one of the most promising possibilities for theranostics in nuclear medicine. Their availability in suitable quantity and quality for medical applications is an open issue and their production with medical cyclotrons represents a scientific and technological challenge. For this purpose, an accurate knowledge of the production cross sections is mandatory. In this paper, we report on the cross section measurement of the reactions ⁴³Ca(p,n)⁴³Sc, ⁴⁴Ca(p,n) ⁴³Sc, ⁴⁶Ti(p,α)⁴³Sc, and ⁴⁴Ca(p,n)⁴⁴Sc at the Bern University Hospital cyclotron. A study of the production yield and purity performed by using commercially available enriched target materials is also presented.

Item Type:

Journal Article (Original Article)

Division/Institute:

10 Strategic Research Centers > Albert Einstein Center for Fundamental Physics (AEC)
08 Faculty of Science > Physics Institute > Laboratory for High Energy Physics (LHEP)

UniBE Contributor:

Carzaniga, Tommaso Stefano; Auger, Martin; Braccini, Saverio; Ereditato, Antonio; Nesteruk, Konrad Pawel and Scampoli, Paola

Subjects:

500 Science > 530 Physics

ISSN:

0969-8043

Publisher:

Elsevier

Language:

English

Submitter:

Marcella Esposito

Date Deposited:

13 Apr 2018 15:56

Last Modified:

29 Oct 2019 08:07

Publisher DOI:

10.1016/j.apradiso.2017.08.013

BORIS DOI:

10.7892/boris.114367

URI:

https://boris.unibe.ch/id/eprint/114367

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