Antibody response to Influenza booster vaccination in Franches-Montagnes stallions supplemented with Equi-Strath : a randomized trial.

van Dorland, Hendrika A; Zanoni, Reto; Gerber, Vinzenz; Jeannerat, Elise; Wiederkehr, Danja; Burger, Dominik (2018). Antibody response to Influenza booster vaccination in Franches-Montagnes stallions supplemented with Equi-Strath : a randomized trial. Veterinary medicine and science, 4(2), pp. 133-139. Wiley 10.1002/vms3.95

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Bio-Strath is a plasmolyzed yeast product enriched with herbs, malt, honey and orange juice. In this study, the effect of Equi-Strath , the adapted product for horses, on the equine immune system was evaluated. A routine influenza booster vaccination was used as a model to study the effects of Equi-Strath supplementation on the immune response. Twenty healthy Franches-Montagnes stallions with pre-existing antibody levels were randomly divided into a study group (SG, n = 10) receiving 0.06 mL/kg bodyweight of Equi-Strath , and a control group (CG, n = 10), receiving the same amount of placebo, daily. The supplement and placebo were given from week 1 until week 14 of the trial. After 10 weeks, the horses were vaccinated with a commercial vaccine containing equine influenza strains of the H3N8 subtype. Antibody titres in blood were measured at day 0 before vaccination, and 14 and 32 days after vaccination. In addition, a complete blood count (CBC) was performed on day 0 and day 32. A linear increase of haemagglutination inhibition titres in both groups was observed after vaccination, but with no difference between treatment groups. CBC components remained unaffected by treatment. In conclusion, daily Equi-Strath supplementation did not affect the adaptive immune response in stallions after a routine commercial H3N8 influenza booster vaccination.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Veterinary Public Health / Herd Health Management
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Equine Clinic
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)

UniBE Contributor:

Gerber, Vinzenz; Jeannerat, Elise and Burger, Dominik

Subjects:

600 Technology > 630 Agriculture

ISSN:

2053-1095

Publisher:

Wiley

Language:

English

Submitter:

Andrea Gassmann-Suter

Date Deposited:

18 Jun 2018 07:27

Last Modified:

08 Feb 2019 11:47

Publisher DOI:

10.1002/vms3.95

PubMed ID:

29851307

Uncontrolled Keywords:

antibody titre equine influenza plasmolyzed yeast vaccination

BORIS DOI:

10.7892/boris.117230

URI:

https://boris.unibe.ch/id/eprint/117230

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