van Dorland, Hendrika A; Zanoni, Reto; Gerber, Vinzenz; Jeannerat, Elise; Wiederkehr, Danja; Burger, Dominik (2018). Antibody response to Influenza booster vaccination in Franches-Montagnes stallions supplemented with Equi-Strath : a randomized trial. Veterinary medicine and science, 4(2), pp. 133-139. Wiley 10.1002/vms3.95
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Bio-Strath is a plasmolyzed yeast product enriched with herbs, malt, honey and orange juice. In this study, the effect of Equi-Strath , the adapted product for horses, on the equine immune system was evaluated. A routine influenza booster vaccination was used as a model to study the effects of Equi-Strath supplementation on the immune response. Twenty healthy Franches-Montagnes stallions with pre-existing antibody levels were randomly divided into a study group (SG, n = 10) receiving 0.06 mL/kg bodyweight of Equi-Strath , and a control group (CG, n = 10), receiving the same amount of placebo, daily. The supplement and placebo were given from week 1 until week 14 of the trial. After 10 weeks, the horses were vaccinated with a commercial vaccine containing equine influenza strains of the H3N8 subtype. Antibody titres in blood were measured at day 0 before vaccination, and 14 and 32 days after vaccination. In addition, a complete blood count (CBC) was performed on day 0 and day 32. A linear increase of haemagglutination inhibition titres in both groups was observed after vaccination, but with no difference between treatment groups. CBC components remained unaffected by treatment. In conclusion, daily Equi-Strath supplementation did not affect the adaptive immune response in stallions after a routine commercial H3N8 influenza booster vaccination.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
05 Veterinary Medicine > Research Foci > Veterinary Public Health / Herd Health Management 05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > ISME Equine Clinic Bern > ISME Equine Clinic, Internal medicine 05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) |
UniBE Contributor: |
Gerber, Vinzenz, Jeannerat, Elise, Burger, Dominik Cyrill |
Subjects: |
600 Technology > 630 Agriculture |
ISSN: |
2053-1095 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Andrea Gassmann-Suter |
Date Deposited: |
18 Jun 2018 07:27 |
Last Modified: |
02 Mar 2023 23:30 |
Publisher DOI: |
10.1002/vms3.95 |
PubMed ID: |
29851307 |
Uncontrolled Keywords: |
antibody titre equine influenza plasmolyzed yeast vaccination |
BORIS DOI: |
10.7892/boris.117230 |
URI: |
https://boris.unibe.ch/id/eprint/117230 |
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