Naguleswaran, Arunasalam; Roditi, Isabel (2017). Rodent-free cyclical transmission of Trypanosoma brucei brucei. Molecular and biochemical parasitology, 217, pp. 16-18. Elsevier 10.1016/j.molbiopara.2017.08.005
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We provide a simple protocol enabling cyclical transmission of Trypanosoma brucei brucei to be performed without the need for mammals. These procedures have two advantages: they are in line with 3R principles of animal use - replace, refine, reduce - and may enable more laboratories to study the complete life cycle.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
08 Faculty of Science > Department of Biology > Institute of Cell Biology |
UniBE Contributor: |
Naguleswaran, Arunasalam, Roditi, Isabel |
Subjects: |
500 Science > 570 Life sciences; biology |
ISSN: |
0166-6851 |
Publisher: |
Elsevier |
Funders: |
[UNSPECIFIED] Howard Hughes Medical Institute ; [UNSPECIFIED] Canton of Bern |
Language: |
English |
Submitter: |
Isabel Roditi |
Date Deposited: |
09 Jul 2018 17:08 |
Last Modified: |
05 Dec 2022 15:14 |
Publisher DOI: |
10.1016/j.molbiopara.2017.08.005 |
PubMed ID: |
28843782 |
Uncontrolled Keywords: |
3R concept Animal replacement Metacyclic forms Salivary glands Trypanosome Tsetse |
BORIS DOI: |
10.7892/boris.117301 |
URI: |
https://boris.unibe.ch/id/eprint/117301 |