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Maurizio, Marina; Masid, Maria; Woods, Kerry; Caldelari, Reto; Doench, John G; Naguleswaran, Arunasalam; Joly, Denis; González-Fernández, Martín; Zemp, Jonas; Borteele, Mélanie; Hatzimanikatis, Vassily; Heussler, Volker; Rottenberg, Sven; Olias, Philipp (2024). Host cell CRISPR genomics and modelling reveal shared metabolic vulnerabilities in the intracellular development of Plasmodium falciparum and related hemoparasites. Nature Communications, 15(1) Springer Nature 10.1038/s41467-024-50405-x
Brühlmann, Francis; Perry, Carmen; Griessen, Charlotte; Gunasekera, Kapila; Reymond, Jean-Louis; Naguleswaran, Arunasalam; Rottenberg, Sven; Woods, Kerry; Olias, Philipp (2024). TurboID mapping reveals the exportome of secreted intrinsically disordered proteins in the transforming parasite Theileria annulata. mBio, 15(6), e0341223. American Society for Microbiology 10.1128/mbio.03412-23
Ajiboye, Jubilee; Uldry, Anne-Christine; Heller, Manfred; Naguleswaran, Arunasalam; Fan, Erkang; Van Voorhis, Wesley C; Hemphill, Andrew; Müller, Joachim (2024). Molecular Targets of the 5-Amido-Carboxamide Bumped Kinase Inhibitor BKI-1748 in Cryptosporidium parvum and HCT-8 Host Cells. International journal of molecular sciences, 25(5) MDPI 10.3390/ijms25052707
Smith, Joseph T; Tylec, Brianna; Naguleswaran, Arunasalam; Roditi, Isabel; Read, Laurie K (2023). Developmental dynamics of mitochondrial mRNA abundance and editing reveal roles for temperature and the differentiation-repressive kinase RDK1 in cytochrome oxidase subunit II mRNA editing. mBio, 14(5), e0185423. American Society for Microbiology 10.1128/mbio.01854-23
Pozzi, Berta; Naguleswaran, Arunasalam; Florini, Francesca; Rezaei, Zahra; Roditi, Isabel (2023). The RNA export factor TbMex67 connects transcription and RNA export in Trypanosoma brucei and sets boundaries for RNA polymerase I. Nucleic acids research, 51(10), pp. 5177-5192. Oxford University Press 10.1093/nar/gkad251
Naguleswaran, Arunasalam; Alves Fernandes, Paula; Bevkal Subramanyaswamy, Shubha; Rehmann, Ruth; Nicholson, Pamela; Roditi, Isabel (2021). Draft genome of Trypanosoma b. brucei EATRO1125 (AnTaR1 serodeme) strain [Dataset]. In: EATRO1125 (AnTaR1 serodeme) pseudo chromosomes.
Naguleswaran, Arunasalam; Alves Fernandes, Paula; Bevkal Subramanyaswamy, Shubha; Rehmann, Ruth; Nicholson, Pamela; Roditi, Isabel (2021). Trypanosoma brucei EATRO1125 draft genome assembly (Contigs) [Dataset]. In: Trypanosoma brucei (EATRO1125) genome contigs.
Haindrich, Alexander C.; Ernst, Viona; Naguleswaran, Arunasalam; Oliveres, Quentin-Florian; Roditi, Isabel; Rentsch, Doris (2021). Nutrient availability regulates proline/alanine transporters in Trypanosoma brucei. Journal of biological chemistry, 296, p. 100566. American Society for Biochemistry and Molecular Biology 10.1016/j.jbc.2021.100566
Bevkal, Shubha; Naguleswaran, Arunasalam; Rehmann, Ruth; Kaiser, Marcel; Heller, Manfred; Roditi, Isabel (2021). An Alba-domain protein required for proteome remodelling during trypanosome differentiation and host transition. PLoS pathogens, 17(1), e1009239. Public Library of Science 10.1371/journal.ppat.1009239
Florini, Francesca; Naguleswaran, Arunasalam; Gharib, Walid H; Bringaud, Frédéric; Roditi, Isabel (2019). Unexpected diversity in eukaryotic transcription revealed by the retrotransposon hotspot family of Trypanosoma brucei. Nucleic acids research, 47(4), pp. 1725-1739. Oxford University Press 10.1093/nar/gky1255
Naguleswaran, Arunasalam; Doiron, Nicholas; Roditi, Isabel (2018). RNA-Seq analysis validates the use of culture-derived Trypanosoma brucei and provides new markers for mammalian and insect life-cycle stages. BMC Genomics, 19(1), p. 227. BioMed Central 10.1186/s12864-018-4600-6
Naguleswaran, Arunasalam; Roditi, Isabel (2017). Rodent-free cyclical transmission of Trypanosoma brucei brucei. Molecular and biochemical parasitology, 217, pp. 16-18. Elsevier 10.1016/j.molbiopara.2017.08.005
Roditi, Isabel; Schumann-Burkard, Gabriela; Naguleswaran, Arunasalam (2016). Environmental sensing by African trypanosomes. Current opinion in microbiology, 32, pp. 26-30. Current Biology Ltd. 10.1016/j.mib.2016.04.011
Naguleswaran, Arunasalam; Gunasekera, Kapila; Schimanski, Bernd; Heller, Manfred; Hemphill, Andrew; Ochsenreiter, Torsten; Roditi, Isabel (2015). Trypanosoma brucei RRM1 is a nuclear RNA-binding protein and modulator of chromatin structure. mBio, 6(2), e00114. American Society for Microbiology 10.1128/mBio.00114-15
Bühlmann, M; Walrad, Pegine; Rico, E; Ivens, A; Capewell, P; Naguleswaran, Arunasalam; Roditi, Isabel; Matthews, K (2015). NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway. Nucleic acids research, 43(9), pp. 4491-4504. Oxford University Press 10.1093/nar/gkv330
Schumann Burkard, Gabriela; Käser, Sandro; de Araújo, Patricia; Schimanski, Bernd; Naguleswaran, Arunasalam; Knüsel, Sebastian; Heller, Manfred; Roditi, Isabel (2013). Nucleolar proteins regulate stage-specific gene expression and ribosomal RNA maturation in Trypanosoma brucei. Molecular microbiology, 88(4), pp. 827-840. Blackwell Science 10.1111/mmi.12227
Müller, Joachim; Naguleswaran, Arunasalam; Müller, Norbert; Hemphill, Andrew (2008). Neospora caninum: functional inhibition of protein disulfide isomerase by the broad-spectrum anti-parasitic drug nitazoxanide and other thiazolides. Experimental parasitology, 118(1), pp. 80-8. Amsterdam: Elsevier 10.1016/j.exppara.2007.06.008
Hemphill, Andrew; Spicher, Martin; Lundström-Stadelmann, Britta; Müller, Joachim; Naguleswaran, Arunasalam; Gottstein, Bruno; Walker, M (2007). Innovative chemotherapeutical treatment options for alveolar and cystic echinococcosis. Parasitology, 134(Pt 12), pp. 1657-70. London: Cambridge University Press 10.1017/S0031182007003198
Esposito, Marco; Moores, Shelley; Naguleswaran, Arunasalam; Müller, Joachim; Hemphill, Andrew (2007). Induction of tachyzoite egress from cells infected with the protozoan Neospora caninum by nitro- and bromo-thiazolides, a class of broad-spectrum anti-parasitic drugs. International journal for parasitology, 37(10), pp. 1143-52. Kidlington, UK: Elsevier 10.1016/j.ijpara.2007.03.007
Cortes, H C E; Mueller, N; Esposito, M; Leitão, A; Naguleswaran, A; Hemphill, A (2007). In vitro efficacy of nitro- and bromo-thiazolyl-salicylamide compounds (thiazolides) against Besnoitia besnoiti infection in Vero cells. Parasitology, 134(Pt 7), pp. 975-85. London: Cambridge University Press 10.1017/S0031182007002417
Vonlaufen, N; Naguleswaran, A; Gianinazzi, C; Hemphill, A (2007). Characterization of the fetuin-binding fraction of Neospora caninum tachyzoites and its potential involvement in host-parasite interactions. Parasitology, 134(Pt 6), pp. 805-17. London: Cambridge University Press 10.1017/S0031182006002186
Naguleswaran, Arunasalam; Spicher, Martin; Vonlaufen, Nathalie; Ortega-Mora, Luis M; Torgerson, Paul; Gottstein, Bruno; Hemphill, Andrew (2006). In vitro metacestodicidal activities of genistein and other isoflavones against Echinococcus multilocularis and Echinococcus granulosus. Antimicrobial agents and chemotherapy, 50(11), pp. 3770-8. Washington, D.C.: American Society for Microbiology 10.1128/AAC.00578-06
Hemphill, A; Vonlaufen, N; Naguleswaran, A (2006). Cellular and immunological basis of the host-parasite relationship during infection with Neospora caninum. Parasitology, 133(Pt 3), pp. 261-78. London: Cambridge University Press 10.1017/S0031182006000485
Scheidegger, Alexandra; Vonlaufen, Nathalie Françoise F.; Naguleswaran, Arunasalam; Gianinazzi, Christian; Müller, Norbert; Leib, Stephen; Hemphill, Andrew (2005). Differential effects of interferon-gamma and tumor necrosis factor-alpha on Toxoplasma gondii proliferation in organotypic rat brain slice cultures. Journal of parasitology, 91(2), pp. 307-315. American Society of Parasitologists 10.1645/GE-379R
