Portal Hypertension and a Stiff Liver.

D'Alitto, Felicia; Scherz, Amina; Margini, Cristina; von Tengg-Kobligk, Hendrik; Montani, Matteo; Pabst, Thomas; Berzigotti, Annalisa (2018). Portal Hypertension and a Stiff Liver. Cureus, 10(6), e2768. 10.7759/cureus.2768

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Portal hypertension (PH) is a common clinical syndrome leading to severe complications. In the western world, about 90% of cases of PH are due to liver cirrhosis, and thanks to the availability of ultrasound elastography methods, this diagnosis is usually confirmed at bedside. We report a case of a patient presenting with PH and ascites initially suspected of suffering from liver cirrhosis. The finding of large hepatomegaly and a massive increase in liver stiffness prompted us to perform a liver biopsy. This revealed no fibrosis, but diffuse primary amyloidosis (AL amyloidosis). We discuss the diagnostic and treatment of this case, with emphasis on non-invasive imaging methods available for diagnosis and follow up.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Scherz, Amina; von Tengg-Kobligk, Hendrik; Pabst Müller, Thomas Niklaus and Berzigotti, Annalisa

Subjects:

600 Technology > 610 Medicine & health
600 Technology

ISSN:

2168-8184

Language:

English

Submitter:

Thi Thao Anh Pham

Date Deposited:

17 Dec 2018 09:06

Last Modified:

23 Jul 2019 14:35

Publisher DOI:

10.7759/cureus.2768

PubMed ID:

30101047

Uncontrolled Keywords:

amyloidosis elastography hvpg liver biopsy liver cirrhosis multiple myeloma

BORIS DOI:

10.7892/boris.122095

URI:

https://boris.unibe.ch/id/eprint/122095

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