Portal hypertension (PH) is a common clinical syndrome leading to severe complications. In the western world, about 90% of cases of PH are due to liver cirrhosis, and thanks to the availability of ultrasound elastography methods, this diagnosis is usually confirmed at bedside. We report a case of a patient presenting with PH and ascites initially suspected of suffering from liver cirrhosis. The finding of large hepatomegaly and a massive increase in liver stiffness prompted us to perform a liver biopsy. This revealed no fibrosis, but diffuse primary amyloidosis (AL amyloidosis). We discuss the diagnostic and treatment of this case, with emphasis on non-invasive imaging methods available for diagnosis and follow up.
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Item Type: |
Journal Article
(Further Contribution)
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Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology 04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology |
UniBE Contributor: |
Scherz, Amina; von Tengg-Kobligk, Hendrik; Pabst Müller, Thomas Niklaus and Berzigotti, Annalisa |
Subjects: |
600 Technology > 610 Medicine & health 600 Technology |
ISSN: |
2168-8184 |
Language: |
English |
Submitter: |
Thi Thao Anh Pham
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Date Deposited: |
17 Dec 2018 09:06 |
Last Modified: |
13 Mar 2021 19:49 |
Publisher DOI: |
10.7759/cureus.2768 |
PubMed ID: |
30101047 |
Uncontrolled Keywords: |
amyloidosis elastography hvpg liver biopsy liver cirrhosis multiple myeloma |
BORIS DOI: |
10.7892/boris.122095 |
URI: |
https://boris.unibe.ch/id/eprint/122095 |
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