Risk analysis for tracheostomy dependency in curatively treated laryngeal cancer with organ preservation.

Anschütz, Lukas; Visini, Miranda; Shelan, Mohamed; Eliçin, Olgun; Giger, Roland (2018). Risk analysis for tracheostomy dependency in curatively treated laryngeal cancer with organ preservation. Head & neck - journal for the sciences and specialties of the head and neck, 40(11), pp. 2469-2475. J. Wiley 10.1002/hed.25373

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BACKGROUND A tracheostomy has an enormous negative impact on the patient's quality of life. The purpose of this study is to describe risk factors for permanent tracheostomies in patients undergoing curative organ-preserving treatment of laryngeal cancer. METHODS The charts of all patients with laryngeal cancer diagnosed at our tertiary referral center were reviewed. Cases receiving a tracheostomy before, during, or after primary organ-preserving treatment were eligible. RESULTS A total of 87 patients who underwent tracheostomies were enrolled in the present study. During follow-up, 48 patients (55%) required a permanent tracheostomy, whereas 39 patients (45%) were decannulated. Multivariate analysis revealed primary radiotherapy (RT; odds ratio [OR] 12.857; P < .001) and recurrence (OR 25.84; P < .001) as independent factors of permanent tracheostomy. CONCLUSION This study identifies primary curative RT and tumor relapse as independent risk factors of permanent tracheostomy dependency in patients with laryngeal cancer undergoing a tracheostomy during or after primary curative organ-preserving treatment.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)

UniBE Contributor:

Anschütz, Lukas Peter; Shelan, Mohamed; Eliçin, Olgun and Giger, Roland

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1043-3074

Publisher:

J. Wiley

Language:

English

Submitter:

Stefan Weder

Date Deposited:

23 Jan 2019 15:14

Last Modified:

29 Oct 2019 05:49

Publisher DOI:

10.1002/hed.25373

PubMed ID:

30307670

Uncontrolled Keywords:

laryngeal cancer organ preservation permanent dependency radiotherapy tracheostomy

BORIS DOI:

10.7892/boris.123706

URI:

https://boris.unibe.ch/id/eprint/123706

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