Anschütz, Lukas; Visini, Miranda; Shelan, Mohamed; Eliçin, Olgun; Giger, Roland (2018). Risk analysis for tracheostomy dependency in curatively treated laryngeal cancer with organ preservation. Head & neck - journal for the sciences and specialties of the head and neck, 40(11), pp. 2469-2475. J. Wiley 10.1002/hed.25373
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BACKGROUND
A tracheostomy has an enormous negative impact on the patient's quality of life. The purpose of this study is to describe risk factors for permanent tracheostomies in patients undergoing curative organ-preserving treatment of laryngeal cancer.
METHODS
The charts of all patients with laryngeal cancer diagnosed at our tertiary referral center were reviewed. Cases receiving a tracheostomy before, during, or after primary organ-preserving treatment were eligible.
RESULTS
A total of 87 patients who underwent tracheostomies were enrolled in the present study. During follow-up, 48 patients (55%) required a permanent tracheostomy, whereas 39 patients (45%) were decannulated. Multivariate analysis revealed primary radiotherapy (RT; odds ratio [OR] 12.857; P < .001) and recurrence (OR 25.84; P < .001) as independent factors of permanent tracheostomy.
CONCLUSION
This study identifies primary curative RT and tumor relapse as independent risk factors of permanent tracheostomy dependency in patients with laryngeal cancer undergoing a tracheostomy during or after primary curative organ-preserving treatment.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT) |
UniBE Contributor: |
Anschütz, Lukas Peter, Shelan, Mohamed, Eliçin, Olgun, Giger, Roland |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1043-3074 |
Publisher: |
J. Wiley |
Language: |
English |
Submitter: |
Stefan Weder |
Date Deposited: |
23 Jan 2019 15:14 |
Last Modified: |
05 Dec 2022 15:24 |
Publisher DOI: |
10.1002/hed.25373 |
PubMed ID: |
30307670 |
Uncontrolled Keywords: |
laryngeal cancer organ preservation permanent dependency radiotherapy tracheostomy |
BORIS DOI: |
10.7892/boris.123706 |
URI: |
https://boris.unibe.ch/id/eprint/123706 |
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