Schimmel, Martin; Srinivasan, Murali; McKenna, Gerald; Müller, Frauke (2018). Effect of advanced age and/or systemic medical conditions on dental implant survival: A systematic review and meta-analysis. Clinical oral implants research, 29(S16), pp. 311-330. Wiley-Blackwell 10.1111/clr.13288
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OBJECTIVES
his review evaluated implant survival in geriatric patients (≥75 years) and/or the impact of systemic medical conditions.
MATERIALS AND METHODS
Systematic literature searches were performed to identify studies reporting on geriatric subjects with dental implants and on implant patients who had any of the seven most common systematic conditions among geriatric patients. Meta-analyses were performed on the postloading implant survival rates. The impact of systemic medical conditions and their respective treatment was qualitatively analyzed.
RESULTS
A total of 6,893 studies were identified; of those, 60 studies were included. The fixed-effects model revealed an overall implant survival of 97.3% (95% CI: 94.3, 98.7; studies = 7) and 96.1% (95% CI: 87.3, 98.9; studies = 3), for 1 and 5 years, respectively. In patients with cardiovascular disease, implant survival may be similar or higher compared to healthy patients. High implant survival rates were reported for patients with Parkinson's disease or diabetes mellitus type II. In patients with cancer, implant survival is negatively affected, namely by radiotherapy. Patients with bone metastases receiving high-dose antiresorptive therapy (ART) carry a high risk for complications after implant surgery. Implant survival was reported to be high in patients receiving low-dose ART for treatment of osteoporosis. No evidence was found on implant survival in patients with dementia, respiratory diseases, liver cirrhosis, or osteoarthritis.
CONCLUSIONS
Implant prostheses in geriatric subjects are a predictable treatment option with a very high rate of implant survival. The functional and psychosocial benefits of such intervention should outweigh the associated risks to common medical conditions.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Reconstructive Dentistry and Gerodontology |
UniBE Contributor: |
Schimmel, Martin |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0905-7161 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Vanda Kummer |
Date Deposited: |
21 Feb 2019 16:51 |
Last Modified: |
05 Dec 2022 15:24 |
Publisher DOI: |
10.1111/clr.13288 |
PubMed ID: |
30328186 |
Uncontrolled Keywords: |
Alzheimer's disease Parkinson's disease aging bisphosphonates cancer cardiovascular disease chronic obstructive pulmonary disease cirrhosis of the liver dementia dental implants depression diabetes mellitus geriatric hypertensive heart disease hyposalivation ischemic heart disease lower respiratory infections medication-related osteonecrosis of the jaw meta-analysis neurocognitive impairment osteoarthritis radiotherapy respiratory diseases stroke systematic review |
BORIS DOI: |
10.7892/boris.123966 |
URI: |
https://boris.unibe.ch/id/eprint/123966 |
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