Lagrèze, Wolf A; Joachimsen, Lutz; Gross, Nikolai; Taschner, Christian; Rössler, Jochen Karl (2019). Sirolimus-induced regression of a large orbital lymphangioma. Orbit, 38(1), pp. 79-80. Taylor & Francis 10.1080/01676830.2018.1436569
Full text not available from this repository.Microcystic lymphatic malformations are difficult to treat surgically, especially when located in the orbital apex. Recently, pharmacologic inhibition of the mTOR pathway by sirolimus was reported as a safe and efficacious treatment option for lymphatic malformations (also known as lymphangiomas). We report the case of a young male patient in which a unilateral, retrobulbar lymphatic malformation regressed to a large extent under treatment with 1 mg sirolimus given orally twice a day over a period of six months.
Item Type: |
Journal Article (Further Contribution) |
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Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine |
UniBE Contributor: |
Rössler, Jochen Karl |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1744-5108 |
Publisher: |
Taylor & Francis |
Language: |
English |
Submitter: |
Anette van Dorland |
Date Deposited: |
26 Feb 2019 08:39 |
Last Modified: |
05 Dec 2022 15:24 |
Publisher DOI: |
10.1080/01676830.2018.1436569 |
PubMed ID: |
29405800 |
Uncontrolled Keywords: |
Lymphangioma lymphatic malformation mTOR orbit sirolimus |
URI: |
https://boris.unibe.ch/id/eprint/124289 |