Lagrèze, Wolf A; Joachimsen, Lutz; Gross, Nikolai; Taschner, Christian; Rössler, Jochen Karl (2019). Sirolimus-induced regression of a large orbital lymphangioma. Orbit, 38(1), pp. 79-80. Taylor & Francis 10.1080/01676830.2018.1436569
Full text not available from this repository. (Request a copy)Microcystic lymphatic malformations are difficult to treat surgically, especially when located in the orbital apex. Recently, pharmacologic inhibition of the mTOR pathway by sirolimus was reported as a safe and efficacious treatment option for lymphatic malformations (also known as lymphangiomas). We report the case of a young male patient in which a unilateral, retrobulbar lymphatic malformation regressed to a large extent under treatment with 1 mg sirolimus given orally twice a day over a period of six months.
Item Type: |
Journal Article (Further Contribution) |
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Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine |
UniBE Contributor: |
Rössler, Jochen Karl |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1744-5108 |
Publisher: |
Taylor & Francis |
Language: |
English |
Submitter: |
Anette van Dorland |
Date Deposited: |
26 Feb 2019 08:39 |
Last Modified: |
05 Dec 2022 15:24 |
Publisher DOI: |
10.1080/01676830.2018.1436569 |
PubMed ID: |
29405800 |
Uncontrolled Keywords: |
Lymphangioma lymphatic malformation mTOR orbit sirolimus |
URI: |
https://boris.unibe.ch/id/eprint/124289 |