Population-Based Linkage of Big Data in Dental Research.

Joda, Tim Alexander; Waltimo, Tuomas; Pauli-Magnus, Christiane; Probst-Hensch, Nicole; Zitzmann, Nicola U (2018). Population-Based Linkage of Big Data in Dental Research. International journal of environmental research and public health, 15(11) MDPI 10.3390/ijerph15112357

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Population-based linkage of patient-level information opens new strategies for dental research to identify unknown correlations of diseases, prognostic factors, novel treatment concepts and evaluate healthcare systems. As clinical trials have become more complex and inefficient, register-based controlled (clinical) trials (RC(C)T) are a promising approach in dental research. RC(C)Ts provide comprehensive information on hard-to-reach populations, allow observations with minimal loss to follow-up, but require large sample sizes with generating high level of external validity. Collecting data is only valuable if this is done systematically according to harmonized and inter-linkable standards involving a universally accepted general patient consent. Secure data anonymization is crucial, but potential re-identification of individuals poses several challenges. Population-based linkage of big data is a game changer for epidemiological surveys in Public Health and will play a predominant role in future dental research by influencing healthcare services, research, education, biotechnology, insurance, social policy and governmental affairs.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Reconstructive Dentistry and Gerodontology

UniBE Contributor:

Joda, Tim

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1661-7827

Publisher:

MDPI

Language:

English

Submitter:

Vanda Kummer

Date Deposited:

19 Mar 2019 15:26

Last Modified:

07 Aug 2024 15:45

Publisher DOI:

10.3390/ijerph15112357

PubMed ID:

30366416

Uncontrolled Keywords:

big data epidemiological research patient-generated health data (PGHD) public health register-based controlled (clinical) trials [RC(C)T]

BORIS DOI:

10.7892/boris.124473

URI:

https://boris.unibe.ch/id/eprint/124473

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