Effect of EpCAM, CD44, CD133 and CD166 expression on patient survival in tumours of the ampulla of Vater

Piscuoglio, Salvatore; Lehmann, Frank S; Zlobec, Inti; Tornillo, Luigi; Dietmaier, Wolfgang; Hartmann, Arndt; Wünsch, Peter H; Sessa, Fausto; Rümmele, Petra; Baumhoer, Daniel; Terracciano, Luigi M (2012). Effect of EpCAM, CD44, CD133 and CD166 expression on patient survival in tumours of the ampulla of Vater. Journal of clinical pathology, 65(2), pp. 140-5. London: BMJ Publishing Group 10.1136/jclinpath-2011-200043

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Carcinomas of the Vaterian system are rare and presumably arise from pre-existing adenomas. According to the cancer stem cell (CSC) hypothesis, only a small subset of tumor cells has the ability to initiate and develop tumor growth. In colorectal cancer, CD44, CD133, CD166 and EpCAM have been proposed to represent CSC marker proteins and their expression has been shown to correlate with patient survival.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Zlobec, Inti

ISSN:

0021-9746

Publisher:

BMJ Publishing Group

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:32

Last Modified:

17 Mar 2015 21:20

Publisher DOI:

10.1136/jclinpath-2011-200043

PubMed ID:

22130902

Web of Science ID:

000299821200009

URI:

https://boris.unibe.ch/id/eprint/12505 (FactScience: 218857)

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