Regel, Ivonne; Merkl, Lisa; Friedrich, Teresa; Burgermeister, Elke; Zimmermann, Wolfgang; Einwächter, Henrik; Herrmann, Ken; Langer, Rupert; Röcken, Christoph; Hofheinz, Ralf; Schmid, Roland; Ebert, Matthias P (2012). Pan-histone deacetylase inhibitor panobinostat sensitizes gastric cancer cells to anthracyclines via induction of CITED2. Gastroenterology, 143(1), 99-109.e10. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2012.03.035
Full text not available from this repository.Chemotherapy modestly prolongs survival of patients with advanced gastric cancer, but strategies are needed to increase its efficacy. Histone deacetylase (HDAC) inhibitors modify chromatin and can block cancer cell proliferation and promote apoptosis.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Langer, Rupert |
ISSN: |
0016-5085 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:32 |
Last Modified: |
05 Dec 2022 14:10 |
Publisher DOI: |
10.1053/j.gastro.2012.03.035 |
PubMed ID: |
22465428 |
Web of Science ID: |
000305781500033 |
URI: |
https://boris.unibe.ch/id/eprint/12521 (FactScience: 218875) |
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