High-grade supraclavicular soft tissue sarcoma as secondary malignancy after successful treatment of acute myeloid leukemia: case report and literature review

Troeltzsch, Matthias; Stimmer, Herbert; Langer, Rupert; Troeltzsch, Markus; Steiner, Timm; Wolff, Klaus-Dietrich (2012). High-grade supraclavicular soft tissue sarcoma as secondary malignancy after successful treatment of acute myeloid leukemia: case report and literature review. Journal of oral and maxillofacial surgery, 70(9), pp. 2211-7. Maryland Heights, Mo.: Elsevier 10.1016/j.joms.2011.10.008

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It is well known that the treatment protocols for hematopoetic neoplasms carry a high risk of long-term oncogenicity. However, few reports have been published of sarcomas as secondary malignancies. An unusual case report of a soft tissue sarcoma appearing as a secondary cancer is presented, with a review of the published data. The present report involves a soft tissue sarcoma of the neck that occurred 18 years after curative treatment of acute myeloid leukemia by induction chemotherapy and bone marrow transplantation. Consecutive graft-versus-host disease affected the cervical skin. Soft tissue sarcomas appearing as secondary tumors are rare in oncology. The presented case describes the appearance of a sarcoma 18 years after curative treatment of acute myeloid leukemia. This is only the second case of this type reported in published studies.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Service Sector > Institute of Pathology
UniBE Contributor:	Langer, Rupert
ISSN:	0278-2391
Publisher:	Elsevier
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:32
Last Modified:	05 Dec 2022 14:10
Publisher DOI:	10.1016/j.joms.2011.10.008
PubMed ID:	22281128
Web of Science ID:	000308319900035
URI:	https://boris.unibe.ch/id/eprint/12525 (FactScience: 218879)