A new era of virus bioinformatics.

Ibrahim, Bashar; McMahon, Dino P; Hufsky, Franziska; Beer, Martin; Deng, Li; Mercier, Philippe Le; Palmarini, Massimo; Thiel, Volker Earl; Marz, Manja (2018). A new era of virus bioinformatics. Virus research, 251, pp. 86-90. Elsevier 10.1016/j.virusres.2018.05.009

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Despite the recognized excellence of virology and bioinformatics, these two communities have interacted surprisingly sporadically, aside from some pioneering work on HIV-1 and influenza. Bringing together the expertise of bioinformaticians and virologists is crucial, since very specific but fundamental computational approaches are required for virus research, particularly in an era of big data. Collaboration between virologists and bioinformaticians is necessary to improve existing analytical tools, cloud-based systems, computational resources, data sharing approaches, new diagnostic tools, and bioinformatic training. Here, we highlight current progress and discuss potential avenues for future developments in this promising era of virus bioinformatics. We end by presenting an overview of current technologies, and by outlining some of the major challenges and advantages that bioinformatics will bring to the field of virology.

Item Type:

Journal Article (Review Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)

UniBE Contributor:

Thiel, Volker Earl

Subjects:

600 Technology > 630 Agriculture
000 Computer science, knowledge & systems > 020 Library & information sciences
600 Technology > 610 Medicine & health

ISSN:

0168-1702

Publisher:

Elsevier

Language:

English

Submitter:

Achim Braun Parham

Date Deposited:

04 Jun 2019 12:25

Last Modified:

25 Oct 2019 20:20

Publisher DOI:

10.1016/j.virusres.2018.05.009

PubMed ID:

29751021

Uncontrolled Keywords:

Bioinformatics Software Virology Viruses

BORIS DOI:

10.7892/boris.127505

URI:

https://boris.unibe.ch/id/eprint/127505

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