Thiel, Volker Earl

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2024

Subissi, Lorenzo; Otieno, James Richard; Worp, Nathalie; Attar Cohen, Homa; Oude Munnink, Bas B; Abu-Raddad, Laith J; Alm, Erik; Barakat, Amal; Barclay, Wendy S; Bhiman, Jinal N; Caly, Leon; Chand, Meera; Chen, Mark; Cullinane, Ann; de Oliveira, Tulio; Drosten, Christian; Druce, Julian; Effler, Paul; El Masry, Ihab; Faye, Adama; ... (2024). An updated framework for SARS-CoV-2 variants reflects the unpredictability of viral evolution. Nature medicine, 30(9), pp. 2400-2403. Springer Nature 10.1038/s41591-024-02949-0

Schön, Jacob; Barut, G Tuba; Trüeb, Bettina Salome; Halwe, Nico Joel; Berenguer Veiga, Inês; Kratzel, Annika; Ulrich, Lorenz; Kelly, Jenna N; Brügger, Melanie; Wylezich, Claudia; Taddeo, Adriano; Aguiar Moreira, Etori; Túrós, Demeter; Grau-Roma, Llorenç; Ahrens, Ann Kathrin; Schlottau, Kore; Britzke, Tobias; Breithaupt, Angele; Corleis, Björn; Kochmann, Jana; ... (2024). A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications. Nature microbiology, 9(8), pp. 2099-2112. Springer Nature 10.1038/s41564-024-01755-1

Gütlin, Yukino; Albertos Torres, Diana; Gensch, Alexander; Schlotterbeck, Ann-Kathrin; Stöger, Laurent; Heller, Stefanie; Infanti, Laura; Barut, Güliz Tuba; Thiel, Volker; Leuzinger, Karoline; Hirsch, Hans H; Buser, Andreas; Egli, Adrian (2024). Anti-SARS-CoV-2 total immunoglobulin and neutralising antibody responses in healthy blood donors throughout the COVID-19 pandemic: a longitudinal observational study. Swiss medical weekly, 154(3408) SMW supporting association 10.57187/s.3408

Leborgne, Nathan GF; Devisme, Christelle; Kozarac, Nedim; Berenguer Veiga, Inês; Ebert, Nadine; Godel, Aurélie; Grau Roma, Llorenç; Scherer, Melanie; Plattet, Philippe; Thiel, Volker; Zimmer, Gert; Taddeo, Adriano; Benarafa, Charaf (2024). Neutrophil proteases are protective against SARS-CoV-2 by degrading the spike protein and dampening virus-mediated inflammation. JCI insight, 9(7) JCI Insight 10.1172/jci.insight.174133

Steiner, Silvio; Kratzel, Annika; Barut, G Tuba; Lang, Reto M; Aguiar Moreira, Etori; Thomann, Lisa; Kelly, Jenna N; Thiel, Volker (2024). SARS-CoV-2 biology and host interactions. Nature reviews. Microbiology, 22(4), pp. 206-225. Springer Nature 10.1038/s41579-023-01003-z

Schmied, Kimberly; Ehmann, Rosina; Kristen-Burmann, Claudia; Ebert, Nadine; Barut, Güliz Tuba; Almeida, Lea; Kelly, Jenna N; Thomann, Lisa; Stalder, Hanspeter; Lang, Reto; Tekes, Gergely; Thiel, Volker (2024). An RNA replicon system to investigate promising inhibitors of feline coronavirus. Journal of virology, 98(2), e0121623. American Society for Microbiology 10.1128/jvi.01216-23

2023

de Melo, Guilherme Dias; Perraud, Victoire; Alvarez, Flavio; Vieites-Prado, Alba; Kim, Seonhee; Kergoat, Lauriane; Coleon, Anthony; Trüeb, Bettina Salome; Tichit, Magali; Piazza, Aurèle; Thierry, Agnès; Hardy, David; Wolff, Nicolas; Munier, Sandie; Koszul, Romain; Simon-Lorière, Etienne; Thiel, Volker; Lecuit, Marc; Lledo, Pierre-Marie; Renier, Nicolas; ... (2023). Author Correction: Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants. Nature communications, 14(1), p. 8024. Nature Publishing Group 10.1038/s41467-023-42800-7

Daniels, Alison; Fletcher, Sarah; Kerr, Holly E M; Kratzel, Annika; Pinto, Rute Maria; Kriplani, Nisha; Craig, Nicky; Hastie, C James; Davies, Paul; Digard, Paul; Thiel, Volker; Tait-Burkard, Christine (2023). One for all-human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory viruses. Journal of virology, 97(9), e0055523. American Society for Microbiology 10.1128/jvi.00555-23

Mhlekude, Baxolele; Postmus, Dylan; Stenzel, Saskia; Weiner, January; Jansen, Jenny; Zapatero-Belinchón, Francisco J; Olmer, Ruth; Richter, Anja; Heinze, Julian; Heinemann, Nicolas; Mühlemann, Barbara; Schroeder, Simon; Jones, Terry C; Müller, Marcel A; Drosten, Christian; Pich, Andreas; Thiel, Volker; Martin, Ulrich; Niemeyer, Daniela; Gerold, Gisa; ... (2023). Pharmacological inhibition of bromodomain and extra-terminal proteins induces an NRF-2-mediated antiviral state that is subverted by SARS-CoV-2 infection. PLoS pathogens, 19(9), e1011657. Public Library of Science 10.1371/journal.ppat.1011657

Kristen-Burmann, Claudia; Rogger, Peter; Berenguer Veiga, Inês; Riebesehl, Stefanie; Rappe, Julie; Ebert, Nadine; Sautter, Carmen A; Kelly, Jenna N; Stalder, Hanspeter; Ehmann, Rosina; Huber, Michael; Posthaus, Horst; Ruggli, Nicolas; Thiel, Volker; Tekes, Gergely (2023). Reverse Genetic Assessment of the Roles Played by the Spike Protein and ORF3 in Porcine Epidemic Diarrhea Virus Pathogenicity. Journal of virology, 97(7), e0196422. American Society for Microbiology 10.1128/jvi.01964-22

de Melo, Guilherme Dias; Perraud, Victoire; Alvarez, Flavio; Vieites-Prado, Alba; Kim, Seonhee; Kergoat, Lauriane; Coleon, Anthony; Trüeb, Bettina Salome; Tichit, Magali; Piazza, Aurèle; Thierry, Agnès; Hardy, David; Wolff, Nicolas; Munier, Sandie; Koszul, Romain; Simon-Lorière, Etienne; Thiel, Volker; Lecuit, Marc; Lledo, Pierre-Marie; Renier, Nicolas; ... (2023). Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants. Nature communications, 14(1), p. 4485. Nature Publishing Group 10.1038/s41467-023-40228-7

Kratzel, Annika; Thiel, Volker (2023). RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles. The Journal of cell biology, 222(7) Rockefeller Institute Press 10.1083/jcb.202306020

Radzikowska, Urszula; Eljaszewicz, Andrzej; Tan, Ge; Stocker, Nino; Heider, Anja; Westermann, Patrick; Steiner, Silvio; Dreher, Anita; Wawrzyniak, Paulina; Rückert, Beate; Rodriguez-Coira, Juan; Zhakparov, Damir; Huang, Mengting; Jakiela, Bogdan; Sanak, Marek; Moniuszko, Marcin; O'Mahony, Liam; Jutel, Marek; Kebadze, Tatiana; Jackson, David J; ... (2023). Author Correction: Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19. Nature Communications, 14(1), p. 3493. Springer Nature 10.1038/s41467-023-39275-x

Capoferri, Gioele; Walti, Carla Simone; Urwyler, Pascal; Ragozzino, Silvio; Passweg, Jakob R; Halter, Jörg; Battegay, Manuel; Baettig, Veronika; Weisser, Maja; Arnold, Brice; Morin, Benedict; Guetlin, Yukino; Torres, Diana Albertos; Barut, Güliz Tuba; Thiel, Volker; Egli, Adrian; Drexler, Beatrice; Khanna, Nina (2023). Dynamics of antibody titers to SARS-CoV-2 and clinical outcomes after sotrovimab pre-exposure prophylaxis early after allogeneic hematopoietic stem cell transplantation. Bone marrow transplantation, 58(5), pp. 597-599. Springer Nature 10.1038/s41409-023-01936-2

Radzikowska, Urszula; Eljaszewicz, Andrzej; Tan, Ge; Stocker, Nino; Heider, Anja; Westermann, Patrick; Steiner, Silvio; Dreher, Anita; Wawrzyniak, Paulina; Rückert, Beate; Rodriguez-Coira, Juan; Zhakparov, Damir; Huang, Mengting; Jakiela, Bogdan; Sanak, Marek; Moniuszko, Marcin; O'Mahony, Liam; Jutel, Marek; Kebadze, Tatiana; Jackson, J David; ... (2023). Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19. Nature communications, 14(1), p. 2329. Nature Publishing Group 10.1038/s41467-023-37470-4

Abdelnabi, Rana; Jochmans, Dirk; Donckers, Kim; Trüeb, Bettina; Ebert, Nadine; Weynand, Birgit; Thiel, Volker; Neyts, Johan (2023). Nirmatrelvir-resistant SARS-CoV-2 is efficiently transmitted in female Syrian hamsters and retains partial susceptibility to treatment. Nature communications, 14(1), p. 2124. Nature Publishing Group 10.1038/s41467-023-37773-6

Kahlert, Christian R; Nigg, Susanne; Onder, Lucas; Dijkman, Ronald; Diener, Liliane; Vidal, Ana G Jop; Rodriguez, Regulo; Vernazza, Pietro; Thiel, Volker; Vidal, Jorge E; Albrich, Werner C (2023). The quorum sensing com system regulates pneumococcal colonisation and invasive disease in a pseudo-stratified airway tissue model. Microbiological research, 268, p. 127297. Elsevier 10.1016/j.micres.2022.127297

Jochmans, Dirk; Liu, Cheng; Donckers, Kim; Stoycheva, Antitsa; Boland, Sandro; Stevens, Sarah K; De Vita, Chloe; Vanmechelen, Bert; Maes, Piet; Trüeb, Bettina; Ebert, Nadine; Thiel, Volker; De Jonghe, Steven; Vangeel, Laura; Bardiot, Dorothée; Jekle, Andreas; Blatt, Lawrence M; Beigelman, Leonid; Symons, Julian A; Raboisson, Pierre; ... (2023). The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir. mBio, 14(1), e0281522. American Society for Microbiology 10.1128/mbio.02815-22

Brüggemann, Yannick; Kratzel, Annika; Almeida, Lea; Kelly, Jenna N; Thiel, Volker; Pfaender, Stephanie (2023). Conserved requirement of autophagy-related effectors during coronavirus replication. Autophagy, 19(2), pp. 731-733. Landes Bioscience 10.1080/15548627.2022.2100617

Chiu, Winston; Schepers, Joost; Francken, Thibault; Vangeel, Laura; Abbasi, Kayvan; Jochmans, Dirk; De Jonghe, Steven; Thibaut, Hendrik Jan; Thiel, Volker; Neyts, Johan; Laporte, Manon; Leyssen, Pieter (2023). Development of a robust and convenient dual-reporter high-throughput screening assay for SARS-CoV-2 antiviral drug discovery. Antiviral research, 210, p. 105506. Elsevier 10.1016/j.antiviral.2022.105506

2022

Beer, Julius; Crotta, Stefania; Breithaupt, Angele; Ohnemus, Annette; Becker, Jan; Sachs, Benedikt; Kern, Lisa; Llorian, Miriam; Ebert, Nadine; Labroussaa, Fabien; Nhu Thao, Tran Thi; Trueeb, Bettina Salome; Jores, Joerg; Thiel, Volker; Beer, Martin; Fuchs, Jonas; Kochs, Georg; Wack, Andreas; Schwemmle, Martin and Schnepf, Daniel (2022). Impaired immune response drives age-dependent severity of COVID-19. The Journal of experimental medicine, 219(12) Rockefeller Univ. Press 10.1084/jem.20220621

Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y

Kelly, Jenna N; Laloli, Laura; V'kovski, Philip; Holwerda, Melle; Portmann, Jasmine; Thiel, Volker; Dijkman, Ronald (2022). Comprehensive single cell analysis of pandemic influenza A virus infection in the human airways uncovers cell-type specific host transcriptional signatures relevant for disease progression and pathogenesis. Frontiers in immunology, 13(978824), p. 978824. Frontiers Research Foundation 10.3389/fimmu.2022.978824

Taddeo, Adriano; Berenguer Veiga, Inês; Devisme, Christelle; Boss, Renate; Plattet, Philippe; Weigang, Sebastian; Kochs, Georg; Thiel, Volker; Benarafa, Charaf; Zimmer, Gert (2022). Optimized intramuscular immunization with VSV-vectored spike protein triggers a superior immune response to SARS-CoV-2. NPJ vaccines, 7(1), p. 82. Springer Nature 10.1038/s41541-022-00508-7

Brandys, Pascal; Montagutelli, Xavier; Merenkova, Irena; Barut, Güliz T; Thiel, Volker; Schork, Nicholas J; Trüeb, Bettina; Conquet, Laurine; Deng, Aihua; Antanasijevic, Aleksandar; Lee, Hyun-Ku; Valière, Martine; Sindhu, Anoop; Singh, Gita; Herold, Jens (2022). A mRNA Vaccine Encoding for a RBD 60-mer Nanoparticle Elicits Neutralizing Antibodies and Protective Immunity Against the SARS-CoV-2 Delta Variant in Transgenic K18-hACE2 Mice. Frontiers in immunology, 13(912898), p. 912898. Frontiers Research Foundation 10.3389/fimmu.2022.912898

Gultom, Mitra; Kratzel, Annika; Portmann, Jasmine; Stalder, Hanspeter; Chanfon Bätzner, Astrid; Gantenbein, Hans; Gurtner, Corinne; Ebert, Nadine; Gad, Hans Henrik; Hartmann, Rune; Posthaus, Horst; Zanolari, Patrik; Pfaender, Stephanie; Thiel, Volker Earl; Dijkman, Ronald (2022). Establishment of well-differentiated camelid airway cultures to study Middle East respiratory syndrome coronavirus. Scientific reports, 12(1), p. 10340. Springer Nature 10.1038/s41598-022-13777-y

Dijkman, Ronald; Verma, Abhishek Kumar; Selvaraj, Muneeswaran; Ghimire, Roshan; Gad, Hans Henrik; Hartmann, Rune; More, Sunil; Perlman, Stanley; Thiel, Volker Earl; Channappanavar, Rudragouda (2022). Effective Interferon Lambda Treatment Regimen To Control Lethal MERS-CoV Infection in Mice. Journal of virology, 96(11), e0036422. American Society for Microbiology 10.1128/jvi.00364-22

Subissi, Lorenzo; von Gottberg, Anne; Thukral, Lipi; Worp, Nathalie; Oude Munnink, Bas B; Rathore, Surabhi; Abu-Raddad, Laith J; Aguilera, Ximena; Alm, Erik; Archer, Brett N; Attar Cohen, Homa; Barakat, Amal; Barclay, Wendy S; Bhiman, Jinal N; Caly, Leon; Chand, Meera; Chen, Mark; Cullinane, Ann; de Oliveira, Tulio; Drosten, Christian; ... (2022). An early warning system for emerging SARS-CoV-2 variants. Nature medicine, 28(6), pp. 1110-1115. Springer Nature 10.1038/s41591-022-01836-w

Wyss, Marianne; Gradauskaite, Vaiva; Ebert, Nadine; Thiel, Volker; Zurbriggen, Andreas; Plattet, Philippe (2022). Efficient Recovery of Attenuated Canine Distemper Virus from cDNA. Virus research, 316, p. 198796. Elsevier 10.1016/j.virusres.2022.198796

Rossetti, Giacomo G; Ossorio, Marianna A; Rempel, Stephan; Kratzel, Annika; Dionellis, Vasilis S; Barriot, Samia; Tropia, Laurence; Gorgulla, Christoph; Arthanari, Haribabu; Thiel, Volker; Mohr, Peter; Gamboni, Remo; Halazonetis, Thanos D (2022). Non-covalent SARS-CoV-2 Mpro inhibitors developed from in silico screen hits. Scientific reports, 12(1), p. 2505. Springer Nature 10.1038/s41598-022-06306-4

Hume, Adam J.; Heiden, Baylee; Olejnik, Judith; Suder, Ellen L.; Ross, Stephen; Scoon, Whitney A.; Bullitt, Esther; Ericsson, Maria; White, Mitchell R.; Turcinovic, Jacquelyn; Tran, T N Thao; Hekman, Ryan M.; Kaserman, Joseph E.; Huang, Jessie; Alysandratos, Konstantinos-Dionysios; Toth, Gabor E.; Jakab, Ferenc; Kotton, Darrell N.; Wilson, Andrew A.; Emili, Andrew; ... (2022). Recombinant Lloviu virus as a tool to study viral replication and host responses. PLoS pathogens, 18(2), e1010268. Public Library of Science 10.1371/journal.ppat.1010268

Pan, Ruangang; Kindler, Eveline; Cao, Liu; Zhou, Yu; Zhang, Zhen; Liu, Qianyun; Ebert, Nadine; Züst, Roland; Sun, Ying; Gorbalenya, Alexander E.; Perlman, Stanley; Thiel, Volker; Chen, Yu; Guo, Deyin; Britton, Paul; Schultz-Cherry, Stacey (2022). N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition. mBio, 13(1), e0366221. American Society for Microbiology 10.1128/mbio.03662-21

Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory

Niemeyer, Daniela; Stenzel, Saskia; Veith, Talitha; Schroeder, Simon; Friedmann, Kirstin; Weege, Friderike; Trimpert, Jakob; Heinze, Julian; Richter, Anja; Jansen, Jenny; Emanuel, Jackson; Kazmierski, Julia; Pott, Fabian; Jeworowski, Lara M.; Olmer, Ruth; Jaboreck, Mark-Christian; Tenner, Beate; Papies, Jan; Walper, Felix; Schmidt, Marie L.; ... (2022). SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression. PLoS biology, 20(11), e3001871. Public Library of Science 10.1371/journal.pbio.3001871

Thomann, Lisa; Thiel, Volker (2022). SARS-CoV-2 mimics a host protein to bypass defences. Nature, 610(7931), pp. 262-263. Springer Nature 10.1038/d41586-022-02930-2

Ulrich, Lorenz; Halwe, Nico Joel; Taddeo, Adriano; Ebert, Nadine; Schön, Jacob; Devisme, Christelle; Trüeb, Bettina Salome; Hoffmann, Bernd; Wider, Manon; Fan, Xiaoyu; Bekliz, Meriem; Essaidi-Laziosi, Manel; Schmidt, Marie Luisa; Niemeyer, Daniela; Corman, Victor Max; Kraft, Anna; Godel, Aurélie; Laloli, Laura; Kelly, Jenna N; Calderon, Brenda M; ... (2022). Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta. Nature, 602(7896), pp. 307-313. Springer Nature 10.1038/s41586-021-04342-0

2021

Kratzel, Annika; Kelly, Jenna N; V'kovski, Philip; Portmann, Jasmine; Brüggemann, Yannick; Todt, Daniel; Ebert, Nadine; Shrestha, Neeta; Plattet, Philippe; Staab-Weijnitz, Claudia A; von Brunn, Albrecht; Steinmann, Eike; Dijkman, Ronald; Zimmer, Gert; Pfaender, Stephanie; Thiel, Volker (2021). A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets. PLoS biology, 19(12), e3001490. Public Library of Science 10.1371/journal.pbio.3001490

Fahmi, Amal; Brügger, Melanie; Démoulins, Thomas; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Bracher, Lisamaria; Wotzkow, Carlos; Blank, Fabian; Thiel, Volker; Baud, David; Alves, Marco P. (2021). SARS-CoV-2 can infect and propagate in human placenta explants. Cell reports. Medicine, 2(12), p. 100456. Elsevier 10.1016/j.xcrm.2021.100456

Tabata, Keisuke; Prasad, Vibhu; Paul, David; Lee, Ji-Young; Pham, Minh-Tu; Twu, Woan-Ing; Neufeldt, Christopher J; Cortese, Mirko; Cerikan, Berati; Stahl, Yannick; Joecks, Sebastian; Tran, Cong Si; Lüchtenborg, Christian; V'kovski, Philip; Hörmann, Katrin; Müller, André C; Zitzmann, Carolin; Haselmann, Uta; Beneke, Jürgen; Kaderali, Lars; ... (2021). Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation. Nature Communications, 12(1), p. 7276. Springer Nature 10.1038/s41467-021-27511-1

Ogando, Natacha S; El Kazzi, Priscila; Zevenhoven-Dobbe, Jessika C; Bontes, Brenda W; Decombe, Alice; Posthuma, Clara C; Thiel, Volker; Canard, Bruno; Ferron, François; Decroly, Etienne; Snijder, Eric J (2021). Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 118(49) National Academy of Sciences NAS 10.1073/pnas.2108709118

Trimpert, Jakob; Adler, Julia M; Eschke, Kathrin; Abdelgawad, Azza; Firsching, Theresa C; Ebert, Nadine; Tran, Thi Nhu Thao; Gruber, Achim D; Thiel, Volker; Osterrieder, Nikolaus; Kunec, Dusan (2021). Live attenuated virus vaccine protects against SARS-CoV-2 variants of concern B.1.1.7 (Alpha) and B.1.351 (Beta). Science Advances, 7(49), eabk0172. American Association for the Advancement of Science 10.1126/sciadv.abk0172

Ricardo-Lax, Inna; Luna, Joseph M; Tran, Thi Nhu Thao; Le Pen, Jérémie; Yu, Yingpu; Hoffmann, H-Heinrich; Schneider, William M; Razooky, Brandon S; Fernandez-Martinez, Javier; Schmidt, Fabian; Weisblum, Yiska; Trüeb, Bettina Salome; Berenguer Veiga, Inês; Schmied, Kimberly; Ebert, Nadine; Michailidis, Eleftherios; Peace, Avery; Sánchez-Rivera, Francisco J; Lowe, Scott W; Rout, Michael P; ... (2021). Replication and single-cycle delivery of SARS-CoV-2 replicons. Science, 374(6571), pp. 1099-1106. American Association for the Advancement of Science 10.1126/science.abj8430

Fenwick, Craig; Turelli, Priscilla; Perez, Laurent; Pellaton, Céline; Esteves-Leuenberger, Line; Farina, Alex; Campos, Jérémy; Lana, Erica; Fiscalini, Flurin; Raclot, Charlène; Pojer, Florence; Lau, Kelvin; Demurtas, Davide; Descatoire, Marc; Joo, Victor S; Foglierini, Mathilde; Noto, Alessandra; Abdelnabi, Rana; Foo, Caroline S; Vangeel, Laura; ... (2021). A highly potent antibody effective against SARS-CoV-2 variants of concern. Cell reports, 37(2), p. 109814. Cell Press 10.1016/j.celrep.2021.109814

Schroeder, Simon; Mache, Christin; Kleine-Weber, Hannah; Corman, Victor M; Muth, Doreen; Richter, Anja; Fatykhova, Diana; Memish, Ziad A; Stanifer, Megan L; Boulant, Steeve; Gultom, Mitra; Dijkman, Ronald; Eggeling, Stephan; Hocke, Andreas; Hippenstiel, Stefan; Thiel, Volker; Pöhlmann, Stefan; Wolff, Thorsten; Müller, Marcel A and Drosten, Christian (2021). Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5. Nature Communications, 12(1), p. 5324. Springer Nature 10.1038/s41467-021-25519-1

Trimpert, Jakob; Dietert, Kristina; Firsching, Theresa C; Ebert, Nadine; Tran, Thi Nhu Thao; Vladimirova, Daria; Kaufer, Susanne; Labroussaa, Fabien; Abdelgawad, Azza; Conradie, Andelé; Höfler, Thomas; Adler, Julia M; Bertzbach, Luca D; Jores, Jörg; Gruber, Achim D; Thiel, Volker; Osterrieder, Nikolaus; Kunec, Dusan (2021). Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding. Cell reports, 36(5), p. 109493. Cell Press 10.1016/j.celrep.2021.109493

Gultom, Mitra; Licheri, Matthias; Laloli, Laura; Wider, Manon; Strässle, Marina; V'kovski, Philip; Steiner, Silvio; Kratzel, Annika; Tran, Thi Nhu Thao; Probst, Lukas; Stalder, Hanspeter; Portmann, Jasmine; Holwerda, Melle; Ebert, Nadine; Stokar-Regenscheit, Nadine; Gurtner, Corinne; Zanolari, Patrik; Posthaus, Horst; Schuller, Simone; Vicente-Santos, Amanda; ... (2021). Susceptibility of Well-Differentiated Airway Epithelial Cell Cultures from Domestic and Wild Animals to Severe Acute Respiratory Syndrome Coronavirus 2. Emerging infectious diseases, 27(7), pp. 1811-1820. Centers for Disease Control and Prevention 10.3201/eid2707.204660

Konings, Frank; Perkins, Mark D; Kuhn, Jens H; Pallen, Mark J; Alm, Erik J; Archer, Brett N; Barakat, Amal; Bedford, Trevor; Bhiman, Jinal N; Caly, Leon; Carter, Lisa L; Cullinane, Anne; de Oliveira, Tulio; Druce, Julian; El Masry, Ihab; Evans, Roger; Gao, George F; Gorbalenya, Alexander E; Hamblion, Esther; Herring, Belinda L; ... (2021). SARS-CoV-2 Variants of Interest and Concern naming scheme conducive for global discourse [comment]. Nature microbiology, 6(7), pp. 821-823. Springer Nature 10.1038/s41564-021-00932-w

Bhatt, Pramod R; Scaiola, Alain; Loughran, Gary; Leibundgut, Marc; Kratzel, Annika; Meurs, Romane; Dreos, René; O'Connor, Kate M; McMillan, Angus; Bode, Jeffrey W; Thiel, Volker; Gatfield, David; Atkins, John F; Ban, Nenad (2021). Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372(6548), pp. 1306-1313. American Association for the Advancement of Science 10.1126/science.abf3546

Lei, Jian; Ma-Lauer, Yue; Han, Yinze; Thoms, Matthias; Buschauer, Robert; Jores, Joerg; Thiel, Volker; Beckmann, Roland; Deng, Wen; Leonhardt, Heinrich; Hilgenfeld, Rolf; von Brunn, Albrecht (2021). The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation. The EMBO journal, 40(11), e102277. EMBO Press 10.15252/embj.2019102277

Stukalov, Alexey; Girault, Virginie; Grass, Vincent; Karayel, Ozge; Bergant, Valter; Urban, Christian; Haas, Darya A; Huang, Yiqi; Oubraham, Lila; Wang, Anqi; Hamad, M Sabri; Piras, Antonio; Hansen, Fynn M; Tanzer, Maria C; Paron, Igor; Zinzula, Luca; Engleitner, Thomas; Reinecke, Maria; Lavacca, Teresa M; Ehmann, Rosina; ... (2021). Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. Nature, 594(7862), pp. 246-252. Springer Nature 10.1038/s41586-021-03493-4

Strässle, Marina; Laloli, Laura; Gultom, Mitra; V'kovski, Philip; Stoffel, Michael H.; Crespo Pomar, Silvia; Chanfon Bätzner, Astrid; Ebert, Nadine; Labroussaa, Fabien; Dijkman, Ronald; Jores, Joerg; Thiel, Volker (2021). Establishment of caprine airway epithelial cells grown in an air-liquid interface system to study caprine respiratory viruses and bacteria. Veterinary microbiology, 257, p. 109067. Elsevier 10.1016/j.vetmic.2021.109067

Stevaert, Annelies; Krasniqi, Besir; Van Loy, Benjamin; Nguyen, Tien; Thomas, Joice; Vandeput, Julie; Jochmans, Dirk; Thiel, Volker; Dijkman, Ronald; Dehaen, Wim; Voet, Arnout; Naesens, Lieve (2021). Betulonic Acid Derivatives Interfering with Human Coronavirus 229E Replication via the nsp15 Endoribonuclease. Journal of medicinal chemistry, 64(9), pp. 5632-5644. American Chemical Society 10.1021/acs.jmedchem.0c02124

Garcia Nicolas, Obdulio; V'kovski, Philip; Zettl, Ferdinand; Zimmer, Gert; Thiel, Volker; Summerfield, Artur (2021). No Evidence for Human Monocyte-Derived Macrophage Infection and Antibody-Mediated Enhancement of SARS-CoV-2 Infection. Frontiers in cellular and infection microbiology, 11(644574), p. 644574. Frontiers 10.3389/fcimb.2021.644574

Agerer, Benedikt; Koblischke, Maximilian; Gudipati, Venugopal; Montaño-Gutierrez, Luis Fernando; Smyth, Mark; Popa, Alexandra; Genger, Jakob-Wendelin; Endler, Lukas; Florian, David M; Mühlgrabner, Vanessa; Graninger, Marianne; Aberle, Stephan W; Husa, Anna-Maria; Shaw, Lisa Ellen; Lercher, Alexander; Gattinger, Pia; Torralba-Gombau, Ricard; Trapin, Doris; Penz, Thomas; Barreca, Daniele; ... (2021). SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses. Science immunology, 6(57) American Association for the Advancement of Science 10.1126/sciimmunol.abg6461

V'kovski, Philip; Gultom, Mitra; Kelly, Jenna N.; Steiner, Silvio; Russeil, Julie; Mangeat, Bastien; Cora, Elisa; Pezoldt, Joern; Holwerda, Melle; Kratzel, Annika; Laloli, Laura; Wider, Manon; Portmann, Jasmine; Tran, Thao; Ebert, Nadine; Stalder, Hanspeter; Hartmann, Rune; Gardeux, Vincent; Alpern, Daniel; Deplancke, Bart; ... (2021). Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium. PLoS biology, 19(3), e3001158. Public Library of Science 10.1371/journal.pbio.3001158

V'kovski, Philip; Kratzel, Annika; Steiner, Silvio; Stalder, Hanspeter; Thiel, Volker (2021). Coronavirus biology and replication: implications for SARS-CoV-2. Nature reviews. Microbiology, 19(3), pp. 155-170. Springer Nature 10.1038/s41579-020-00468-6

Zhou, Bin; Tran, Thi Nhu Thao; Hoffmann, Donata; Taddeo, Adriano; Ebert, Nadine; Labroussaa, Fabien; Pohlmann, Anne; King, Jacqueline; Steiner, Silvio; Kelly, Jenna N.; Portmann, Jasmine; Halwe, Nico Joel; Ulrich, Lorenz; Trüeb, Bettina Salome; Fan, Xiaoyu; Hoffmann, Bernd; Wang, Li; Thomann, Lisa; Lin, Xudong; Stalder, Hanspeter; ... (2021). SARS-CoV-2 spike D614G change enhances replication and transmission. Nature, 592(7852), pp. 122-127. Springer Nature 10.1038/s41586-021-03361-1

2020

Hufsky, Franziska; Beerenwinkel, Niko; Meyer, Irmtraud M; Roux, Simon; Cook, Georgia May; Kinsella, Cormac M; Lamkiewicz, Kevin; Marquet, Mike; Nieuwenhuijse, David F; Olendraite, Ingrida; Paraskevopoulou, Sofia; Young, Francesca; Dijkman, Ronald; Ibrahim, Bashar; Kelly, Jenna; Le Mercier, Philippe; Marz, Manja; Ramette, Alban; Thiel, Volker (2020). The International Virus Bioinformatics Meeting 2020. Viruses, 12(12) MDPI 10.3390/v12121398

Ancar, Rachel; Li, Yize; Kindler, Eveline; Cooper, Daphne A; Ransom, Monica; Thiel, Volker; Weiss, Susan R; Hesselberth, Jay R; Barton, David J (2020). Physiologic RNA targets and refined sequence specificity of coronavirus EndoU. RNA - a publication of the RNA Society, 26(12), pp. 1976-1999. Cold Spring Harbor Laboratory Press 10.1261/rna.076604.120

Meng, Xiang-Jin; Thiel, Volker (2020). Emerging and re-emerging porcine viruses. Virus research, 290, p. 198198. Elsevier 10.1016/j.virusres.2020.198198

Gasbarri, Matteo; V'kovski, Philip; Torriani, Giulia; Thiel, Volker; Stellacci, Francesco; Tapparel, Caroline; Cagno, Valeria (2020). SARS-CoV-2 Inhibition by Sulfonated Compounds. Microorganisms, 8(12) MDPI 10.3390/microorganisms8121894

Holwerda, Melle; V'kovski, Philip; Wider, Manon; Thiel, Volker; Dijkman, Ronald (2020). Identification of an Antiviral Compound from the Pandemic Response Box that Efficiently Inhibits SARS-CoV-2 Infection In Vitro. Microorganisms, 8(12) MDPI 10.3390/microorganisms8121872

Pfaender, Stephanie; Mar, Katrina B; Michailidis, Eleftherios; Kratzel, Annika; Boys, Ian N; V'kovski, Philip; Fan, Wenchun; Kelly, Jenna N.; Hirt, Dagny; Ebert, Nadine; Stalder, Hanspeter; Kleine-Weber, Hannah; Hoffmann, Markus; Heinrich Hoffmann, H; Saeed, Mohsan; Dijkman, Ronald; Steinmann, Eike; Wight-Carter, Mary; McDougal, Matthew B; Hanners, Natasha W; ... (2020). LY6E impairs coronavirus fusion and confers immune control of viral disease. Nature microbiology, 5(11), pp. 1330-1339. Springer Nature 10.1038/s41564-020-0769-y

Schubert, Katharina; Karousis, Evangelos D.; Jomaa, Ahmad; Scaiola, Alain; Echeverria, Blanca; Gurzeler, Lukas-Adrian; Leibundgut, Marc; Thiel, Volker; Mühlemann, Oliver; Ban, Nenad (2020). SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nature structural & molecular biology, 27(10), pp. 959-966. Springer Nature 10.1038/s41594-020-0511-8

Kratzel, Annika; Steiner, Silvio; Todt, Daniel; V'kovski, Philip; Brueggemann, Yannick; Steinmann, Joerg; Steinmann, Eike; Thiel, Volker; Pfaender, Stephanie (2020). Temperature-dependent surface stability of SARS-CoV-2. Journal of infection, 81(3), pp. 452-482. Elsevier 10.1016/j.jinf.2020.05.074

Kratzel, Annika; Todt, Daniel; V'kovski, Philip; Steiner, Silvio; Gultom, Mitra; Tran, Thi Nhu Thao; Ebert, Nadine; Holwerda, Melle; Steinmann, Jörg; Niemeyer, Daniela; Dijkman, Ronald; Kampf, Günter; Drosten, Christian; Steinmann, Eike; Thiel, Volker; Pfaender, Stephanie (2020). Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols. Emerging infectious diseases, 26(7), pp. 1592-1595. Centers for Disease Control and Prevention 10.3201/eid2607.200915

Tran, Thi Nhu Thao; Labroussaa, Fabien; Ebert, Nadine; V'kovski, Philip; Stalder, Hanspeter; Portmann, Jasmine; Kelly, Jenna; Steiner, Silvio; Holwerda, Melle; Kratzel, Annika; Gultom, Mitra; Schmied, Kimberly; Laloli, Laura; Hüsser, Linda; Wider, Manon; Pfaender, Stephanie; Hirt, Dagny; Cippà, Valentina; Crespo-Pomar, Silvia; Schröder, Simon; ... (2020). Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform. Nature, 582(7813), pp. 561-565. Springer Nature 10.1038/s41586-020-2294-9

Blockus, Sebastian; Sake, Svenja M; Wetzke, Martin; Grethe, Christina; Graalmann, Theresa; Pils, Marina; Le Goffic, Ronan; Galloux, Marie; Prochnow, Hans; Rox, Katharina; Hüttel, Stephan; Rupcic, Zeljka; Wiegmann, Bettina; Dijkman, Ronald; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Duprex, W Paul; Thiel, Volker; Hansen, Gesine; Brönstrup, Mark; ... (2020). Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry. Antiviral research, 177, p. 104774. Elsevier 10.1016/j.antiviral.2020.104774

Thiel, Volker; Jores, Jörg (2020). Ein Klon geht um die Welt. Pipette - Swiss laboratory medicine(2), pp. 16-17. EMH Schweizerischer Ärzteverlag AG

Thiel, Volker (2020). Viral RNA in an m6A disguise. Nature microbiology, 5(4), pp. 531-532. Springer Nature 10.1038/s41564-020-0689-x

Cong, Yingying; Ulasli, Mustafa; Schepers, Hein; Mauthe, Mario; V'kovski, Philip; Kriegenburg, Franziska; Thiel, Volker; de Haan, Cornelis A M; Reggiori, Fulvio (2020). Nucleocapsid Protein Recruitment to Replication-Transcription Complexes Plays a Crucial Role in Coronaviral Life Cycle. Journal of virology, 94(4) American Society for Microbiology 10.1128/JVI.01925-19

V'kovski, Philip; Steiner, Silvio; Thiel, Volker (2020). Proximity Labeling for the Identification of Coronavirus-Host Protein Interactions. Methods in molecular biology, 2203, pp. 187-204. Springer 10.1007/978-1-0716-0900-2_14

Tran, Thi Nhu Thao; Labroussaa, Fabien; Ebert, Nadine; Jores, Jörg; Thiel, Volker (2020). In-Yeast Assembly of Coronavirus Infectious cDNA Clones Using a Synthetic Genomics Pipeline. Methods in molecular biology, 2203, pp. 167-184. Springer 10.1007/978-1-0716-0900-2_13

2019

Zhao, Ye; Cheng, Jinlong; Xu, Gang; Thiel, Volker; Zhang, Guozhong (2019). Successful establishment of a reverse genetic system for QX-type infectious bronchitis virus and technical improvement of the rescue procedure. Virus research, 272, p. 197726. Elsevier 10.1016/j.virusres.2019.197726

Jonsdottir, Hulda R.; Marti, Sabrina; Geerts, Dirk; Rodriguez, Regulo; Thiel, Volker; Dijkman, Ronald (2019). Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions. Viruses, 11(8) MDPI 10.3390/v11080747

Kratzel, Annika; Thiel, Volker; Pfaender, Stephanie (2019). Zoonotic coronavirus infections. Pipette - Swiss laboratory medicine(4), pp. 18-19. EMH Schweizerischer Ärzteverlag AG

Contu, Lara; Steiner, Silvio; Thiel, Volker; Mühlemann, Oliver (2019). The Role of Stress Granules and the Nonsense-mediated mRNA Decay Pathway in Antiviral Defence. CHIMIA, 73(6), pp. 374-379. Schweizerische Chemische Gesellschaft 10.2533/chimia.2019.374

Hufsky, Franziska; Ibrahim, Bashar; Modha, Sejal; Clokie, Martha R J; Deinhardt-Emmer, Stefanie; Dutilh, Bas E; Lycett, Samantha; Simmonds, Peter; Thiel, Volker; Abroi, Aare; Adriaenssens, Evelien M; Escalera-Zamudio, Marina; Kelly, Jenna Nicole; Lamkiewicz, Kevin; Lu, Lu; Susat, Julian; Sicheritz, Thomas; Robertson, David L; Marz, Manja (2019). The Third Annual Meeting of the European Virus Bioinformatics Center. Viruses, 11(5) MDPI 10.3390/v11050420

V'kovski, Philip; Gerber, Markus; Kelly, Jenna Nicole; Pfänder, Stephanie; Ebert, Nadine; Braga Lagache, Sophie; Simillion, Cedric; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Bruggmann, Rémy; Stoffel, Michael Hubert; Heller, Manfred; Dijkman, Ronald; Thiel, Volker Earl (2019). Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling. eLife, 8 eLife Sciences Publications 10.7554/eLife.42037

2018

Alves, Marco; Vielle, Nathalie Jane; Thiel, Volker Earl; Pfänder, Stephanie (2018). Research Models and Tools for the Identification of Antivirals and Therapeutics against Zika Virus Infection. Viruses, 10(11) MDPI 10.3390/v10110593

Garcia Nicolas, Obdulio; V'kovski, Philip; Vielle, Nathalie J.; Ebert, Nadine; Züst, R; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Vieyres, G; Stoffel, Michael; Schweizer, Matthias; Summerfield, Artur; Engler, O; Pietschmann, T; Todt, D; Alves, Marco; Thiel, Volker; Pfänder, Stephanie (2018). The small compound inhibitor K22 displays broad antiviral activity against different members of the family Flaviviridae and offers potential as pan-viral inhibitor. Antimicrobial agents and chemotherapy, 62(11) American Society for Microbiology 10.1128/AAC.01206-18

Muth, Doreen; Corman, Victor Max; Roth, Hanna; Binger, Tabea; Dijkman, Ronald; Gottula, Lina Theresa; Gloza-Rausch, Florian; Balboni, Andrea; Battilani, Mara; Rihtarič, Danijela; Toplak, Ivan; Ameneiros, Ramón Seage; Pfeifer, Alexander; Thiel, Volker Earl; Drexler, Jan Felix; Müller, Marcel Alexander; Drosten, Christian (2018). Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission. Scientific Reports, 8(1), p. 15177. Nature Publishing Group 10.1038/s41598-018-33487-8

Thiel, Volker Earl (2018). Synthetic viruses-Anything new? PLoS pathogens, 14(10), e1007019. Public Library of Science 10.1371/journal.ppat.1007019

V'kovski, Philip; Gerber, M; Kelly, Jenna Nicole; Pfänder, Stephanie; Ebert, Nadine; Braga, Sophie Marie-Pierre; Simillion, Cedric André Marie; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Bruggmann, Rémy; Stoffel, Michael Hubert; Heller, Manfred; Dijkman, Ronald; Thiel, Volker Earl (14 September 2018). Determination of host cell proteins constituting the molecular microenvironment of coronavirus replicase complexes by proximity-labeling (bioRxiv). Cold Spring Harbor Laboratory 10.1101/417907

Ibrahim, Bashar; McMahon, Dino P; Hufsky, Franziska; Beer, Martin; Deng, Li; Mercier, Philippe Le; Palmarini, Massimo; Thiel, Volker Earl; Marz, Manja (2018). A new era of virus bioinformatics. Virus research, 251, pp. 86-90. Elsevier 10.1016/j.virusres.2018.05.009

Milewska, Aleksandra; Kindler, Eveline Patricia; V'Kovski, Philip; Zeglen, S; Ochman, M; Thiel, Volker Earl; Rajfur, Z; Pyrc, K (2018). APOBEC3-mediated restriction of RNA virus replication. Scientific Reports, 8(1), p. 5960. Nature Publishing Group 10.1038/s41598-018-24448-2

Rappe, Julie Christiane Françoise; de Wilde, Adriaan; Di, Han; Müller, Christin; Stalder, Hanspeter; V'Kovski, Philip; Snijder, Eric; Brinton, Margo A; Ziebuhr, John; Ruggli, Nicolas; Thiel, Volker Earl (2018). Antiviral activity of K22 against members of the order Nidovirales. Virus research, 246, pp. 28-34. Elsevier 10.1016/j.virusres.2018.01.002

Hufsky, Franziska; Ibrahim, Bashar; Beer, Martin; Deng, Li; Mercier, Philippe Le; McMahon, Dino P; Palmarini, Massimo; Thiel, Volker Earl; Marz, Manja (2018). Virologists-Heroes need weapons. PLoS pathogens, 14(2), e1006771. Public Library of Science 10.1371/journal.ppat.1006771

2017

Behrendt, Patrick; Perin, Paula; Menzel, Nicolas; Banda, Dominic; Pfänder, Stephanie; Alves, Marco; Thiel, Volker Earl; Meulemann, Phillip; Colpitts, Che C; Schang, Luis M; Vondran, Florian W R; Anggakusuma, A; Manns, Michael P; Steinmann, Eike; Pietschmann, Thomas (2017). Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry. Antiviral research, 147, pp. 19-28. Elsevier 10.1016/j.antiviral.2017.09.006

Pfänder, Stephanie; Walter, Stephanie; Grabski, Elena; Todt, Daniel; Bruening, Janina; Romero-Brey, Inés; Gather, Theresa; Brown, Richard J P; Hahn, Kerstin; Puff, Christina; Pfankuche, Vanessa M; Hansmann, Florian; Postel, Alexander; Becher, Paul; Thiel, Volker Earl; Kalinke, Ulrich; Wagner, Bettina; Bartenschlager, Ralf; Baumgärtner, Wolfgang; Feige, Karsten; ... (2017). Immune protection against reinfection with nonprimate hepacivirus. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 114(12), E2430-E2439. National Academy of Sciences NAS 10.1073/pnas.1619380114

Siddharta, Anindya; Pfänder, Stephanie; Vielle, Nathalie Jane; Dijkman, Ronald; Friesland, Martina; Becker, Britta; Yang, Jaewon; Engelmann, Michael; Todt, Daniel; Windisch, Marc P; Brill, Florian H; Steinmann, Joerg; Steinmann, Jochen; Becker, Stephan; Alves, Marco; Pietschmann, Thomas; Eickmann, Markus; Thiel, Volker Earl; Steinmann, Eike (2017). Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. Journal of infectious diseases, 215(6), pp. 902-906. Oxford University Press 10.1093/infdis/jix046

Kindler, Eveline Patricia; Gil-Cruz, Cristina; Spanier, Julia; Li, Yize; Wilhelm, Jochen; Rabouw, Huib H; Züst, Roland; Hwang, Mihyun; V'Kovski, Philip; Stalder, Hanspeter; Marti, Sabrina; Habjan, Matthias; Cervantes-Barragan, Luisa; Elliot, Ruth; Karl, Nadja; Gaughan, Christina; van Kuppeveld, Frank J M; Silverman, Robert H; Keller, Markus; Ludewig, Burkhard; ... (2017). Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS pathogens, 13(2), e1006195. Public Library of Science 10.1371/journal.ppat.1006195

Pfänder, Stephanie; Vielle, Nathalie Jane; Ebert, Nadine; Steinmann, E; Alves, Marco; Thiel, Volker Earl (2017). Inactivation of Zika virus in human breast milk by prolonged storage or pasteurization. Virus research, 228, pp. 58-60. Elsevier 10.1016/j.virusres.2016.11.025

2016

Wu, Nai-Huei; Yang, Wei; Beineke, Andreas; Dijkman, Ronald; Matrosovich, Mikhail; Baumgärtner, Wolfgang; Thiel, Volker Earl; Valentin-Weigand, Peter; Meng, Fandan; Herrler, Georg (2016). The differentiated airway epithelium infected by influenza viruses maintains the barrier function despite a dramatic loss of ciliated cells. Scientific Reports, 6(39668), p. 39668. Nature Publishing Group 10.1038/srep39668

Greub, Gilbert; Holliger, Christof; Sanglard, Dominique; Schrenzel, Jacques; Thiel, Volker; Viollier, Patrick (2016). The Swiss Society of Microbiology: Small Bugs, Big Questions and Cool Answers. CHIMIA, 70(12), pp. 874-877. Schweizerische Chemische Gesellschaft 10.2533/chimia.2016.874

Corman, Victor M; Eckerle, Isabella; Memish, Ziad A; Liljander, Anne M; Dijkman, Ronald; Jonsdottir, Hulda; Juma Ngeiywa, Kisi J Z; Kamau, Esther; Younan, Mario; Al Masri, Malakita; Assiri, Abdullah; Gluecks, Ilona; Musa, Bakri E; Meyer, Benjamin; Müller, Marcel A; Hilali, Mosaad; Bornstein, Set; Wernery, Ulrich; Thiel, Volker; Jores, Jörg; ... (2016). Link of a ubiquitous human coronavirus to dromedary camels. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(35), pp. 9864-9869. National Academy of Sciences NAS 10.1073/pnas.1604472113

Kaderali, Lars; Thiel, Volker Earl (2016). Systems biology of viral infection. Virus research, 218, p. 1. Elsevier 10.1016/j.virusres.2016.05.020

Kindler, Eveline Patricia; Thiel, Volker Earl (2016). SARS-CoV and IFN: Too Little, Too Late. Cell host & microbe, 19(2), pp. 139-141. Cell Press 10.1016/j.chom.2016.01.012

Kindler, Eveline Patricia; Thiel, Volker Earl; Weber, F (2016). Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response. Advances in virus research, 96, pp. 219-243. Elsevier 10.1016/bs.aivir.2016.08.006

2015

Corman, Victor Max; Baldwin, Heather J; Tateno, Adriana Fumie; Zerbinati, Rodrigo Melim; Annan, Augustina; Owusu, Michael; Nkrumah, Evans Ewald; Maganga, Gael Darren; Oppong, Samuel; Adu-Sarkodie, Yaw; Vallo, Peter; da Silva Filho, Luiz Vicente Ribeiro Ferreira; Leroy, Eric M; Thiel, Volker Earl; van der Hoek, Lia; Poon, Leo L M; Tschapka, Marco; Drosten, Christian; Drexler, Jan Felix (2015). Evidence for an Ancestral Association of Human Coronavirus 229E with Bats. Journal of virology, 89(23), pp. 11858-11870. American Society for Microbiology 10.1128/JVI.01755-15

Lauber, C; Vieyres, G; Terczyńska-Dyla, E; Anggakusuma, X; Dijkman, Ronald; Gad, H H; Akhtar, H; Geffers, R; Vondran, F W R; Thiel, Volker Earl; Kaderali, L; Pietschmann, T; Hartmann, R (2015). Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells. Genes and immunity, 16(6), pp. 414-421. Nature Publishing Group 10.1038/gene.2015.23

Mielech, Anna M; Deng, Xufang; Chen, Yafang; Kindler, Eveline Patricia; Wheeler, Dorthea L; Mesecar, Andrew D; Thiel, Volker Earl; Perlman, Stanley; Baker, Susan C (2015). Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis. Journal of virology, 89(9), pp. 4907-4917. American Society for Microbiology 10.1128/JVI.00338-15

V'Kovski, Philip; Al-Mulla, Hawaa; Thiel, Volker Earl; Neuman, Benjamin W (2015). New insights on the role of paired membrane structures in coronavirus replication. Virus research, 202, pp. 33-40. Elsevier 10.1016/j.virusres.2014.12.021

Pas, Suzan D.; Patel, Pranav; Reusken, Chantal; Domingo, Cristina; Corman, Victor M.; Drosten, Christian; Dijkman, Ronald; Thiel, Volker Earl; Nowotny, Norbert; Koopmans, Marion P.G.; Niedrig, Matthias (2015). First international external quality assessment of molecular diagnostics for Mers-CoV. Journal of clinical virology, 69, pp. 81-85. Elsevier 10.1016/j.jcv.2015.05.022

2014

Kindler, E; Thiel, Volker Earl (2014). To sense or not to sense viral RNA--essentials of coronavirus innate immune evasion. Current opinion in microbiology, 20, pp. 69-75. Elsevier 10.1016/j.mib.2014.05.005

Lundin, Anna; Dijkman, Ronald; Bergström, Tomas; Kann, Nina; Adamiak, Beata; Hannoun, Charles; Kindler, Eveline; Jónsdóttir, Hulda R; Muth, Doreen; Kint, Joeri; Forlenza, Maria; Müller, Marcel A; Drosten, Christian; Thiel, Volker Earl; Trybala, Edward (2014). Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus. PLoS pathogens, 10(5), e1004166. Public Library of Science 10.1371/journal.ppat.1004166

Al-Mulla, Hawaa M N; Turrell, Lauren; Smith, Nicola M; Payne, Luke; Baliji, Surendranath; Züst, Roland; Thiel, Volker Earl; Baker, Susan C; Siddell, Stuart G; Neuman, Benjamin W (2014). Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions. mBio, 5(2), e01107-e01113. American Society for Microbiology 10.1128/mBio.01107-13

Thiel, Volker Earl; Thiel, Heinz-Jürgen; Tekes, Gergely (2014). Tackling feline infectious peritonitis via reverse genetics. Bioengineered, 5(6), pp. 396-400. Taylor & Francis 10.4161/bioe.32133

2013

Dijkman, Ronald; Jebbink, Maarten F; Koekkoek, Sylvie M; Deijs, Martin; Jonsdottir, Hulda R.; Molenkamp, Richard; Ieven, Margareta; Goossens, Herman; Thiel, Volker; van der Hoek, Lia (2013). Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism. Journal of virology, 87(11), pp. 6081-6090. American Society for Microbiology 10.1128/JVI.03368-12

Kindler, Eveline; Jonsdottir, Hulda R.; Muth, Doreen; Hamming, Ole J; Hartmann, Rune; Rodriguez, Regulo; Geffers, Robert; Fouchier, Ron A M; Drosten, Christian; Müller, Marcel A; Dijkman, Ronald; Thiel, Volker (2013). Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential. mBio, 4(1), e00611-e00612. American Society for Microbiology 10.1128/mBio.00611-12

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