Caporro, Matteo; Rossetti, Andrea O; Seiler, Andrea; Kustermann, Thomas; Nguepnjo Nguissi, Nathalie Ata; Pfeiffer, Christian; Zimmermann, Rebekka; Hänggi, Matthias; Oddo, Mauro; De Lucia, Marzia; Zubler, Frédéric (2019). Electromyographic reactivity measured with scalp-EEG contributes to prognostication after cardiac arrest. Resuscitation, 138, pp. 146-152. Elsevier Science Ireland 10.1016/j.resuscitation.2019.03.014
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AIM
To assess whether stimulus-induced modifications of electromyographic activity observed on scalp EEG have a prognostic value in comatose patients after cardiac arrest.
METHODS
184 adult patients from a multi-centric prospective register who underwent an early EEG after cardiac arrest were included. Auditory and somatosensory stimulation was performed during EEG-recording. EEG reactivity (EEG-R) and EMG reactivity (EMG-R) were retrospectively assessed visually by board-certified electroencephalographers, and compared with clinical outcome (cerebral performance category, CPC) at three months. A favorable functional outcome was defined as CPC 1-2, an unfavorable outcome as CPC 3-5.
RESULTS
Both EEG-R and EMG-R were predictors for good outcome (EEG-R accuracy 72% (95%-CI 66-79), sensitivity 86% (78-93), specificity 60% (50-69); EMG-R accuracy 65% (58-72), sensitivity 61% (51-75), specificity 69% (60-78)). When reactivity was defined as EEG-R and/or EMG-R, the accuracy was 73% (67-70), the sensitivity 94% (90-99), and the specificity 53% (43-63).
CONCLUSION
Taking EMG into account when assessing reactivity of EEG seems to reduce false negative predictions for identifying patients with favorable outcome after cardiac arrest.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology 04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic of Intensive Care |
UniBE Contributor: |
Caporro, Matteo, Seiler, Andrea Barbara, Hänggi, Matthias, Zubler, Frédéric |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0300-9572 |
Publisher: |
Elsevier Science Ireland |
Language: |
English |
Submitter: |
Mirella Aeberhard |
Date Deposited: |
15 Jul 2019 11:19 |
Last Modified: |
05 Dec 2022 15:27 |
Publisher DOI: |
10.1016/j.resuscitation.2019.03.014 |
PubMed ID: |
30885825 |
Uncontrolled Keywords: |
EEG EMG cardiac arrest coma prognostication reactivity |
BORIS DOI: |
10.7892/boris.128800 |
URI: |
https://boris.unibe.ch/id/eprint/128800 |
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