04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic of Intensive Care

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Kjaer, Maj-Brit Nørregaard; Meyhoff, Tine Sylvest; Madsen, Martin Bruun; Hjortrup, Peter Buhl; Møller, Morten Hylander; Egerod, Ingrid; Wetterslev, Jørn; Lange, Theis; Cronhjort, Maria; Laake, Jon Henrik; Jakob, Stephan M.; Nalos, Marek; Pettilä, Ville; van der Horst, Iwan C C; Ostermann, Marlies; Mouncey, Paul; Cecconi, Maurizio; Ferrer, Ricard; L N G Malbrain, Manu; Ahlstedt, Christian; ... (2020). Long-term patient-important outcomes after septic shock: a protocol for 1-year follow-up of the CLASSIC-trial. Acta anaesthesiologica Scandinavica, 64(3), pp. 410-416. Wiley-Blackwell 10.1111/aas.13519

Meyer, Patricia; Grandgirard, Denis; Lehner, Marika; Haenggi, Matthias; Leib, Stephen (2020). Grafted neural progenitor cells persist in the injured site and differentiate neuronally in a rodent model of cardiac arrest-induced global brain ischemia. (In Press). Stem cells and development Mary Ann Liebert 10.1089/scd.2019.0190

Zuercher, Patrick; Dziewas, Rainer; Schefold, Joerg C. (2020). Dysphagia in the intensive care unit: a (multidisciplinary) call to action. (In Press). Intensive care medicine Springer-Verlag 10.1007/s00134-020-05937-3

Barth, Rike; Zubler, Frederic; Weck, Anja; Haenggi, Matthias; Schindler, Kaspar; Wiest, Roland; Wagner, Franca (2020). Topography of MR lesions correlates with standardized EEG pattern in early comatose survivors after cardiac arrest. (In Press). Resuscitation Elsevier 10.1016/j.resuscitation.2020.01.014

Fujii, Tomoko; Luethi, Nora; Young, Paul J; Frei, Daniel R; Eastwood, Glenn M; French, Craig J; Deane, Adam M; Shehabi, Yahya; Hajjar, Ludhmila A; Oliveira, Gisele; Udy, Andrew A; Orford, Neil; Edney, Samantha J; Hunt, Anna L; Judd, Harriet L; Bitker, Laurent; Cioccari, Luca; Naorungroj, Thummaporn; Yanase, Fumitaka; Bates, Samantha; ... (2020). Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial. (In Press). JAMA : the journal of the American Medical Association American Medical Association 10.1001/jama.2019.22176

Bräutigam, Konstantin; Hohl, Anja; Hewer, Ekkehard; Langer, Rupert; Jakob, Stephan (2020). Myeloid Sarcoma Mimicking Endocarditis: An Autopsy Case. (In Press). International journal of surgical pathology, p. 1066896919900011. Sage 10.1177/1066896919900011

Schefold, Jörg C.; Gerber, Joël L; Angehrn, Michelle C; Müller, Martin; Messmer, Anna S.; Leichtle, Alexander B; Fiedler, Georg M; Exadaktylos, Aristomenis; Pfortmüller, Carmen (2020). Renal Function-Adjusted D-Dimer Levels in Critically Ill Patients With Suspected Thromboembolism. (In Press). Critical care medicine Wolters Kluwer Health 10.1097/CCM.0000000000004204

Werner-Moller, Per; Berger, David; Takala, Jukka (2020). Letter to the Editor: Venous return and the physical connection between distribution of segmental pressures and volumes. American journal of physiology - heart and circulatory physiology, 318(1), H203-H204. American Physiological Society 10.1152/ajpheart.00698.2019

Guidet, Bertrand; de Lange, Dylan W; Boumendil, Ariane; Leaver, Susannah; Watson, Ximena; Boulanger, Carol; Szczeklik, Wojciech; Artigas, Antonio; Morandi, Alessandro; Andersen, Finn; Zafeiridis, Tilemachos; Jung, Christian; Moreno, Rui; Walther, Sten; Oeyen, Sandra; Schefold, Jörg C.; Cecconi, Maurizio; Marsh, Brian; Joannidis, Michael; Nalapko, Yuriy; ... (2020). The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study. Intensive care medicine, 46(1), pp. 57-69. Springer-Verlag 10.1007/s00134-019-05853-1

Levis, Anja; Greif, Robert; Hautz, Wolf; Hunziker, Lukas; Fehr, Tobias; Haenggi, Matthias (January 2020). Endovascular balloon occlusion in refractory cardiac arrest patients: preliminary results. Critical care medicine, 48(1), p. 705. Wolters Kluwer Health 10.1097/01.ccm.0000645744.86616.68

Zante, Björn; Blaum, Wolf E.; Schefold, Jörg C. (2020). Physiology education for intensive care medicine residents: A 15-minute interactive peer-led flipped classroom session. PLoS ONE, 15(1), e0228257. Public Library of Science 10.1371/journal.pone.0228257

Mija, R.; Zubak, I.; Schuetz, A.; Glas, M.; Fung, C.; Jakob, S. M.; Beck, J.; Z'Graggen, W. J.; Bloch, Andreas (2020). Correlation of optic nerve and optic nerve sheath diameter with intracranial pressure in pigs. PLoS ONE, 15(2), e0228242. Public Library of Science 10.1371/journal.pone.0228242

Eggmann, Sabrina; Luder, Gere; Verra, Martin L; Irincheeva, Irina; Bastiaenen, Caroline H G; Jakob, Stephan M (2020). Functional ability and quality of life in critical illness survivors with intensive care unit acquired weakness: a secondary analysis of a randomised controlled trial : DATASET [Dataset].


Gerber, Stephan M.; Jeitziner, Marie-Madlen; Knobel, Samuel E. J.; Mosimann, Urs P.; Müri, René M.; Jakob, Stephan M.; Nef, Tobias (2019). Perception and Performance on a Virtual Reality Cognitive Stimulation for Use in the Intensive Care Unit: A Non-randomized Trial in Critically Ill Patients (In Press). Frontiers in medicine, 6(287) Frontiers 10.3389/fmed.2019.00287

Kuhnke, Melanie; Albrecht, Roland; Schefold, Joerg C.; Paal, Peter (2019). Successful resuscitation from prolonged hypothermic cardiac arrest without extracorporeal life support: a case report. Journal of medical case reports, 13(1), p. 354. BioMed Central 10.1186/s13256-019-2282-6

Leshkasheli, Lika; Kutateladze, Mzia; Balarjishvili, Nana; Bolkvadze, Darejan; Save, Jonathan; Oechslin, Frank; Que, Yok-Ai; Resch, Grégory (2019). Efficacy of Newly Isolated and Highly Potent Bacteriophages in a Mouse Model of XDRAB Bacteremia. Journal of global antimicrobial resistance, 19, pp. 255-261. Elsevier 10.1016/j.jgar.2019.05.005

Rubio, Ignacio; Osuchowski, Marcin F; Shankar-Hari, Manu; Skirecki, Tomasz; Winkler, Martin Sebastian; Lachmann, Gunnar; La Rosée, Paul; Monneret, Guillaume; Venet, Fabienne; Bauer, Michael; Brunkhorst, Frank M; Kox, Matthijs; Cavaillon, Jean-Marc; Uhle, Florian; Weigand, Markus A; Flohé, Stefanie B; Wiersinga, W Joost; Martin-Fernandez, Marta; Almansa, Raquel; Martin-Loeches, Ignacio; ... (2019). Current gaps in sepsis immunology: new opportunities for translational research. The lancet. Infectious diseases, 19(12), e422-e436. Elsevier 10.1016/S1473-3099(19)30567-5

Amrein, Karin; Parekh, Dhruv; Westphal, Sabine; Preiser, Jean-Charles; Berghold, Andrea; Riedl, Regina; Eller, Philipp; Schellongowski, Peter; Thickett, David; Meybohm, Patrick (2019). Effect of high-dose vitamin D3 on 28-day mortality in adult critically ill patients with severe vitamin D deficiency: a study protocol of a multicentre, placebo-controlled double-blind phase III RCT (the VITDALIZE study). BMJ open, 9(11), e031083. BMJ Publishing Group 10.1136/bmjopen-2019-031083

Ogura, Asako; Tsurumi, Amy; Que, Yok-Ai; Almpani, Marianna; Zheng, Hui; Tompkins, Ronald G; Ryan, Colleen M; Rahme, Laurence G (2019). Associations between clinical characteristics and the development of multiple organ failure after severe burns in adult patients. Burns, 45(8), pp. 1775-1782. Elsevier 10.1016/j.burns.2019.02.014

Prazak, Josef; Iten, Manuela; Cameron, David Robert; Save, Jonathan Florian; Grandgirard, Denis; Resch, Gregory; Göpfert, Christine; Leib, Stephen L.; Takala, Jukka; Jakob, Stephan; Que, Yok-Ai; Hänggi, Matthias (2019). Bacteriophages Improve Outcome in Experimental Staphylococcus Aureus Ventilator Associated Pneumonia. American journal of respiratory and critical care medicine, 200(9), pp. 1126-1133. American Thoracic Society 10.1164/rccm.201812-2372OC

Müller, Martin; Schefold, Joerg C.; Leichtle, Alexander Benedikt; Srivastava, David Shiva; Lindner, G; Exadaktylos, Aristomenis K.; Pfortmüller, Carmen (2019). qSOFA score not predictive of in-hospital mortality in emergency patients with decompensated liver cirrhosis. Medizinische Klinik, Intensivmedizin und Notfallmedizin, 114(8), pp. 724-732. Springer 10.1007/s00063-018-0477-z

Granholm, Anders; Lange, Theis; Anthon, Carl Thomas; Marker, Søren; Krag, Mette; Meyhoff, Tine Sylvest; Wise, Matt P; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Jörg C.; Wetterslev, Jørn; Perner, Anders; Møller, Morten Hylander (2019). Time to onset of gastrointestinal bleeding in the SUP-ICU trial: a preplanned substudy. Acta anaesthesiologica Scandinavica, 63(10), pp. 1346-1356. Wiley-Blackwell 10.1111/aas.13459

Zante, Björn; Tinguley, Pascale; Ott, Daniel; Dettmer, Matthias; Gloor, Beat; Schefold, Jörg (2019). Enteritis necroticans - megacolon with massive portal venous gas embolization in a patient after malabsorptive bariatric surgery. Anaesthesiology intensive therapy, 51(4), pp. 333-334. Termedia Publishing House 10.5114/ait.2019.88573

Cameron, David R.; Ramette, Alban; Prazak, Josef; Entenza, José; Hänggi, Matthias; Que, Yok-Ai; Resch, Grégory (2019). Draft Genome Sequence of Methicillin-Resistant Staphylococcus aureus Strain AW7, Isolated from a Patient with Bacteremia. Microbiology resource announcements, 8(40) American Society for Microbiology 10.1128/MRA.00806-19

Sprung, Charles L; Ricou, Bara; Hartog, Christiane S; Maia, Paulo; Mentzelopoulos, Spyros D; Weiss, Manfred; Levin, Phillip D; Galarza, Laura; de la Guardia, Veronica; Schefold, Jörg C.; Baras, Mario; Joynt, Gavin M; Bülow, Hans-Henrik; Nakos, Georgios; Cerny, Vladimir; Marsch, Stephan; Girbes, Armand R; Ingels, Catherine; Miskolci, Orsolya; Ledoux, Didier; ... (2019). Changes in End-of-Life Practices in European Intensive Care Units From 1999 to 2016. (In Press). JAMA : the journal of the American Medical Association, pp. 1-12. American Medical Association 10.1001/jama.2019.14608

Waskowski, Jan; Schefold, Joerg C.; Stüber, Frank (2019). [Prophylactic use of tranexamic acid in noncardiac surgery : Update 2017]. Medizinische Klinik - Intensivmedizin und Notfallmedizin, 114(7), pp. 642-649. Springer-Medizin-Verlag 10.1007/s00063-018-0402-5

Zante, Björn; Erdös, Gabor (2019). Risk of Prolonged Mechanical Ventilation After Cardiac Surgery: Predicting the Unpredictable? Journal of cardiothoracic and vascular anesthesia, 33(10), pp. 2717-2718. Elsevier 10.1053/j.jvca.2019.04.008

Marker, Søren; Krag, Mette; Perner, Anders; Wetterslev, Jørn; Lange, Theis; Wise, Matt P; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Jörg Christian; Rasmussen, Bodil S; Elkmann, Thomas; Bestle, Morten; Arenkiel, Bjørn; Laake, Jon H; Kamper, Maj K; Lång, Maarit; Pawlowicz-Dworzanska, Malgorzata B; Karlsson, Sari; ... (2019). Pantoprazole in ICU patients at risk for gastrointestinal bleeding-1-year mortality in the SUP-ICU trial. Acta anaesthesiologica Scandinavica, 63(9), pp. 1184-1190. Wiley-Blackwell 10.1111/aas.13436

Meyhoff, Tine Sylvest; Hjortrup, Peter Buhl; Møller, Morten Hylander; Wetterslev, Jørn; Lange, Theis; Kjaer, Maj-Brit Nørregaard; Jonsson, Andreas Bender; Hjortsø, Carl Johan Steensen; Cronhjort, Maria; Laake, Jon Henrik; Jakob, Stephan M.; Nalos, Marek; Pettilä, Ville; van der Horst, Iwan; Ostermann, Marlies; Mouncey, Paul; Rowan, Kathy; Cecconi, Maurizio; Ferrer, Ricard; Malbrain, Manu L N G; ... (2019). Conservative vs liberal fluid therapy in septic shock (CLASSIC) trial-Protocol and statistical analysis plan. Acta anaesthesiologica Scandinavica, 63(9), pp. 1262-1271. Wiley-Blackwell 10.1111/aas.13434

Bachmann, Kaspar; Vasireddy, Radhakrishna; Vogt, Andreas; Berger, David (27 September 2019). Calculating pulmonary blood flow from CO2 elimination. An in vitro model. Intensive care medicine experimental, 7(Suppl 3), p. 144. Springer

Wernerman, Jan; Christopher, Kenneth B; Annane, Djillali; Casaer, Michael P; Coopersmith, Craig M; Deane, Adam M; De Waele, Elisabeth; Elke, Gunnar; Ichai, Carole; Karvellas, Constantine J; McClave, Stephen A; Oudemans-van Straaten, Heleen M; Rooyackers, Olav; Stapleton, Renee D; Takala, Jukka; van Zanten, Arthur R H; Wischmeyer, Paul E; Preiser, Jean-Charles; Vincent, Jean-Louis (2019). Metabolic support in the critically ill: a consensus of 19. Critical care, 23(1), p. 318. BioMed Central 10.1186/s13054-019-2597-0

Schefold, Jörg Christian; Krag, Mette; Marker, Søren; Perner, Anders; Wetterslev, Jørn; Wise, Matt P.; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Lange, Theis; Møller, Morten Hylander (2019). Outcomes of Prophylactic Pantoprazole in Adult Intensive Care Unit Patients Receiving Dialysis: Results of a Randomized Trial. American journal of nephrology, 50(4), pp. 312-319. Karger 10.1159/000502732

Kohler, Andreas; Moller, Per Werner; Frey, Sabrina; Tinguely, Pascale; Candinas, Daniel; Obrist, Dominik; Jakob, Stephan; Beldi, Guido (2019). Portal hyperperfusion after major liver resection and associated sinusoidal damage is a therapeutic target to protect the remnant liver. American journal of physiology - gastrointestinal and liver physiology, 317(3), G264-G274. American Physiological Society 10.1152/ajpgi.00113.2019

Kustermann, Thomas; Nguepnjo Nguissi, Nathalie Ata; Pfeiffer, Christian; Hänggi, Matthias; Kurmann, Rebekka; Zubler, Frédéric; Oddo, Mauro; Rossetti, Andrea O.; De Lucia, Marzia (2019). Electroencephalography-based power spectra allow coma outcome prediction within 24 hours of cardiac arrest. Resuscitation, 142, pp. 162-167. Elsevier Science Ireland 10.1016/j.resuscitation.2019.05.021

Merz, Tobias; Cioccari, Luca; Frey, Pascal Marcel; Bloch, Andreas; Berger, David; Zante, Björn; Jakob, Stephan; Takala, Jukka (2019). Correction to: Continual hemodynamic monitoring with a single-use transesophageal echocardiography probe in critically ill patients with shock: a randomized controlled clinical trial. Intensive care medicine, 45(9), p. 1330. Springer-Verlag 10.1007/s00134-019-05700-3

Perren, Andrea; Zürcher, Patrick; Schefold, Joerg C. (2019). Clinical Approaches to Assess Post-extubation Dysphagia (PED) in the Critically Ill. Dysphagia, 34(4), pp. 475-486. Springer 10.1007/s00455-019-09977-w

Merz, Tobias; Cioccari, Luca; Frey, Pascal Marcel; Bloch, Andreas; Berger, David; Zante, Björn; Jakob, Stephan; Takala, Jukka (2019). Continual hemodynamic monitoring with a single-use transesophageal echocardiography probe in critically ill patients with shock: a randomized controlled clinical trial. Intensive care medicine, 45(8), pp. 1093-1102. Springer-Verlag 10.1007/s00134-019-05670-6

Osawa, Eduardo Atsushi; Cutuli, Salvatore Lucio; Bitker, Laurent; Canet, Emmanuel; Cioccari, Luca; Iguchi, Naoya; Lankadeva, Yugeesh R; Eastwood, Glenn M; Evans, Roger G; May, Clive N; Bellomo, Rinaldo (2019). Effect of Furosemide on Urinary Oxygenation in Patients with Septic Shock. Blood purification, 48(4), pp. 336-345. Karger 10.1159/000501512

Zürcher, Patrick; Moret, Céline; Schefold, Jörg C. (2019). Dysphagia in the intensive care unit in Switzerland (DICE) - results of a national survey on the current standard of care. Swiss medical weekly, 149(w20111), w20111. EMH Media 10.4414/smw.2019.20111

Boschung-Pasquier, Léna; Atkinson, Andrew; Kastner, Leonie Kassandra; Banholzer, Sarah; Haschke, Manuel; Buetti, Niccolò; Furrer, Dominique I; Hauser, Christoph; Jent, Philipp; Que, Yok-Ai; Furrer, Hansjakob; Babouee Flury, Baharak (2019). Cefepime neurotoxicity: thresholds and risk factors. A Retrospective Cohort study. (In Press). Clinical microbiology and infection Elsevier 10.1016/j.cmi.2019.06.028

Moller, Per W; Berger, David (2019). Reply to "What if what you are looking for is not there?" and "Towards a functional definition of euvolemia". Journal of applied physiology, 127(1), p. 276. American Physiological Society 10.1152/japplphysiol.00229.2019

Lüthi, Nora; Cioccari, Luca; Eastwood, Glenn; Biesenbach, Peter; Morgan, Rhys; Sprogis, Stephanie; Young, Helen; Peck, Leah; Knee Chong, Christine; Moore, Sandra; Moon, Kylie; Ekinci, Elif I; Deane, Adam M; Bellomo, Rinaldo; Mårtensson, Johan (2019). Hospital-acquired complications in intensive care unit patients with diabetes: A before-and-after study of a conventional versus liberal glucose control protocol. Acta anaesthesiologica Scandinavica, 63(6), pp. 761-768. Wiley-Blackwell 10.1111/aas.13354

Hedenstierna, Göran; Tokics, Leif; Scaramuzzo, Gaetano; Rothen, Hans Ulrich; Edmark, Lennart; Öhrvik, John (2019). Oxygenation Impairment during Anesthesia: Influence of Age and Body Weight. Anesthesiology, 131(1), pp. 46-57. Wolters Kluwer Health 10.1097/ALN.0000000000002693

Shehabi, Yahya; Howe, Belinda D; Bellomo, Rinaldo; Arabi, Yaseen M; Bailey, Michael; Bass, Frances E; Bin Kadiman, Suhaini; McArthur, Colin J; Murray, Lynnette; Reade, Michael C; Seppelt, Ian M; Takala, Jukka; Wise, Matt P; Webb, Steven A (2019). Early Sedation with Dexmedetomidine in Critically Ill Patients. The New England journal of medicine, 380(26), pp. 2506-2517. Massachusetts Medical Society 10.1056/NEJMoa1904710

Pfortmüller, Carmen; Messmer, Anna S.; Hess, Benjamin; Reineke, David; Jakob, Laura; Wenger, Stefanie; Waskowski, Jan; Zürcher, Patrick; Stöhr, Frederik; Erdös, Gabor; Lüdi, Markus M.; Jakob, Stephan M.; Englberger, Lars; Schefold, Jörg C. (2019). Hypertonic saline for fluid resuscitation after cardiac surgery (HERACLES): study protocol for a preliminary randomised controlled clinical trial. Trials, 20(1), p. 357. BioMed Central 10.1186/s13063-019-3420-6

Zante, Björn; Reichenspurner, Hermann; Kubik, Mathias; Schefold, Jörg Christian; Kluge, Stefan (2019). Increased admission central venous-arterial CO difference predicts ICU-mortality in adult cardiac surgery patients. Heart & lung, 48(5), pp. 421-427. Elsevier 10.1016/j.hrtlng.2019.05.015

Werner Möller, Per; Sondergaard, Soren; Jakob, Stephan; Takala, Jukka; Berger, David (2019). Effect of volume status on the estimation of mean systemic filling pressure. Journal of applied physiology, 126(6), pp. 1503-1513. American Physiological Society 10.1152/japplphysiol.00897.2018

Scherbakov, Nadja; Pietrock, Charlotte; Sandek, Anja; Ebner, Nicole; Valentova, Miroslava; Springer, Jochen; Schefold, Joerg C.; von Haehling, Stephan; Anker, Stefan D; Norman, Kristina; Haeusler, Karl Georg; Doehner, Wolfram (2019). Body weight changes and incidence of cachexia after stroke. Journal of cachexia, sarcopenia and muscle, 10(3), pp. 611-620. Wiley 10.1002/jcsm.12400

Pfortmüller, Carmen; Barbani, Maria Teresa; Schefold, Jörg Christian; Hage, Elias; Heim, Albert; Zimmerli, Stefan (2019). Severe acute respiratory distress syndrome (ARDS) induced by human adenovirus B21: Report on 2 cases and literature review. Journal of critical care, 51, pp. 99-104. Elsevier 10.1016/j.jcrc.2019.02.019

Bitker, Laurent; Cutuli, Salvatore L; Cioccari, Luca; Osawa, Eduardo A; Toh, Lisa; Luethi, Nora; Young, Helen; Peck, Leah; Eastwood, Glenn M; Mårtensson, Johan; Bellomo, Rinaldo (2019). Sepsis uncouples serum C-peptide and insulin levels in critically ill patients with type 2 diabetes mellitus. Critical care and resuscitation, 21(2), pp. 87-95. College of Intensive Care Medicine of Australia and New Zealand

Eggimann, Philippe; Pagani, Jean-Luc; Dupuis-Lozeron, Elise; Ms, Bruce Ekholm; Thévenin, Marie-Josèphe; Joseph, Christine; Revelly, Jean-Pierre; Que, Yok-Ai (2019). Sustained reduction of catheter-associated bloodstream infections with enhancement of catheter bundle by chlorhexidine dressings over 11 years. Intensive care medicine, 45(6), pp. 823-833. Springer-Verlag 10.1007/s00134-019-05617-x

Pfortmueller, Carmen A.; Faeh, Livia; Müller, Martin; Eberle, Balthasar; Jenni, Hansjörg; Zante, Björn; Prazak, Josef; Englberger, Lars; Takala, Jukka; Jakob, Stephan M. (2019). Fluid management in patients undergoing cardiac surgery: effects of an acetate- versus lactate-buffered balanced infusion solution on hemodynamic stability (HEMACETAT). Critical care, 23(1), p. 159. BioMed Central 10.1186/s13054-019-2423-8

Werner Möller, Per; Hana, Anisa; Heinisch, Paul Philipp; Liu, Shengchen; Djafarzadeh, Siamak; Hänggi, Matthias; Bloch, Andreas; Takala, Jukka; Jakob, Stephan; Berger, David (2019). The Effects of Vasoconstriction and Volume Expansion on Veno-Arterial ECMO Flow. Shock, 51(5), pp. 650-658. Lippincott Williams & Wilkins 10.1097/SHK.0000000000001197

Marker, Søren; Perner, Anders; Wetterslev, Jørn; Krag, Mette; Lange, Theis; Wise, Matt P; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Jörg Christian; Møller, Morten Hylander (2019). Pantoprazole prophylaxis in ICU patients with high severity of disease: a post hoc analysis of the placebo-controlled SUP-ICU trial. Intensive care medicine, 45(5), pp. 609-618. Springer-Verlag 10.1007/s00134-019-05589-y

Caporro, Matteo; Rossetti, Andrea O; Seiler, Andrea; Kustermann, Thomas; Nguepnjo Nguissi, Nathalie Ata; Pfeiffer, Christian; Zimmermann, Rebekka; Hänggi, Matthias; Oddo, Mauro; De Lucia, Marzia; Zubler, Frédéric (2019). Electromyographic reactivity measured with scalp-EEG contributes to prognostication after cardiac arrest. Resuscitation, 138, pp. 146-152. Elsevier Science Ireland 10.1016/j.resuscitation.2019.03.014

Hilty, Matthias Peter; Merz, Tobias Michael; Hefti, Urs; Ince, Can; Maggiorini, Marco; Pichler Hefti, Jacqueline (2019). Recruitment of non-perfused sublingual capillaries increases microcirculatory oxygen extraction capacity throughout ascent to 7126 m. The journal of physiology, 597(10), pp. 2623-2638. The Physiological Society 10.1113/JP277590

Zante, Björn; Schefold, Joerg C. (2019). Teaching End-of-Life Communication in Intensive Care Medicine: Review of the Existing Literature and Implications for Future Curricula. Journal of intensive care medicine, 34(4), pp. 301-310. Sage 10.1177/0885066617716057

Zürcher, Patrick; Moret, Céline S; Dziewas, Rainer; Schefold, Jörg Christian (2019). Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management. Critical care, 23(1), p. 103. BioMed Central 10.1186/s13054-019-2400-2

Cioccari, Luca; Luethi, Nora; Glassford, Neil J; Bellomo, Rinaldo (2019). The normal cardiac index in older healthy individuals: a scoping review. Critical care and resuscitation, 21(1), pp. 9-17. College of Intensive Care Medicine of Australia and New Zealand

Bachmann, Kaspar F.; Nebiker, Mathias; Johner, Caroline; Bregy, Rachel; Schaller, André; Novak, Urban; Jakob, Stephan M. (2019). Rare Case of Transcutaneous Oxygen Desaturation in a Cancer Patient: A Case Report and Diagnostic Approach for a Recurrent Problem. A&A practice, 12(4), pp. 96-98. Lippincott Williams & Wilkins 10.1213/XAA.0000000000000855

Z'Graggen, Werner Josef; Schefold, Joerg C. (2019). Critical Illness Myopathy: Glucocorticoids revisited? Acta physiologica, 225(2), e13205. Blackwell Publishing 10.1111/apha.13205

Eggimann, Philippe; Que, Yok-Ai; Rebeaud, Fabien (2019). Measurement of pancreatic stone protein in the identification and management of sepsis. Biomarkers in medicine, 13(2), pp. 135-145. Future Medicine 10.2217/bmm-2018-0194

Pantet, Olivier; Stoecklin, Patricia; Charrière, Mélanie; Voirol, Pierre; Vernay, Arnaud; Berger, Mette M (2019). Trace element repletion following severe burn injury: A dose-finding cohort study. Clinical nutrition, 38(1), pp. 246-251. Elsevier 10.1016/j.clnu.2018.01.025

Jault, Patrick; Leclerc, Thomas; Jennes, Serge; Pirnay, Jean Paul; Que, Yok-Ai; Resch, Gregory; Rousseau, Anne Françoise; Ravat, François; Carsin, Hervé; Le Floch, Ronan; Schaal, Jean Vivien; Soler, Charles; Fevre, Cindy; Arnaud, Isabelle; Bretaudeau, Laurent; Gabard, Jérôme (2019). Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial. The lancet. Infectious diseases, 19(1), pp. 35-45. Elsevier 10.1016/S1473-3099(18)30482-1

Schefold, Joerg C.; Messmer, Anna S.; Wenger, Stefanie; Müller, Lionel; von Haehling, Stephan; Doehner, Wolfram; McPhee, Jamie S; Fux, Michaela; Rösler, Kai M; Scheidegger, Olivier; Olariu, Radu; Z'Graggen, Werner; Rezzi, Serge; Grathwohl, Dominik; Konz, Tobias; Takala, Jukka; Cuenoud, Bernard; Jakob, Stephan M. (2019). Nutrient pattern analysis in critically ill patients using Omics technology (NAChO) - Study protocol for a prospective observational study. Medicine, 98(1), e13937. Lippincott Williams & Wilkins 10.1097/MD.0000000000013937

Porteous, Jennifer; Cioccari, Luca; Ancona, Paolo; Osawa, Eduardo; Jones, Kelly; Gow, Paul; Angus, Peter; Warrillow, Stephen; Bellomo, Rinaldo (2019). Outcome of Acetaminophen-Induced Acute Liver Failure Managed Without Intracranial Pressure Monitoring or Transplantation. Liver transplantation, 25(1), pp. 35-44. Wiley 10.1002/lt.25377

Berger, David; Werner Möller, Per; Takala, Jukka (2019). Reply to “Is the Guytonian framework justified in explaining heart lung interactions?” and “Venous return, mean systemic pressure and getting the right answer for the wrong reason”. Annals of translational medicine, 7(8), p. 186. AME Publishing Company 10.21037/atm.2019.04.50

Waskowski, Jan; Pfortmüller, Carmen; Erdös, Gabor; Bühlmann, Roman; Messmer, Anna Sarah; Lüdi, Markus; Schmidli, Jürg; Schefold, Jörg Christian (2019). Mannitol for the Prevention of Peri-Operative Acute Kidney Injury: A Systematic Review. European journal of vascular and endovascular surgery EJVES, 58(1), pp. 130-140. Elsevier 10.1016/j.ejvs.2019.02.003

Sommerstein, Rami; Merz, Tobias M.; Berger, Sabine; Krämer, Julia G.; Marschall, Jonas; Hilty, Markus (2019). Patterns in the longitudinal oropharyngeal microbiome evolution related to ventilator-associated pneumonia. Antimicrobial Resistance and Infection Control, 8, p. 81. BioMed Central 10.1186/s13756-019-0530-6

Gerber, Stephan M.; Jeitziner, Marie-Madlen; Sänger, Simon D; Knobel, Samuel E. J.; Marchal-Crespo, Laura; Müri, René M.; Schefold, Jörg C.; Jakob, Stephan M.; Nef, Tobias (2019). Comparing the Relaxing Effects of Different Virtual Reality Environments in the Intensive Care Unit: Observational Study. JMIR perioperative medicine, 2(2), e15579. JMIR Publications 10.2196/15579

Fischer, Corinne; Goldberg, Johannes; Vulcu, Sonja; Wagner, Franca; Schöni, Daniel; Söll, Nicole; Hänggi, Matthias; Schefold, Jörg; Fung, Christian; Beck, Jürgen; Raabe, Andreas; Z'Graggen, Werner J. (2019). Nimodipine-Induced Blood Pressure Changes Can Predict Delayed Cerebral Ischemia. Frontiers in neurology, 10(1161), p. 1161. Frontiers Media S.A. 10.3389/fneur.2019.01161

Utermöhlen, Olaf; Jakobshagen, Kristin; Blissenbach, Birgit; Wiegmann, Katja; Merz, Tobias; Pichler Hefti, Jacqueline; Krönke, Martin (2019). Emergence of AnnexinVpos CD31neg CD42blow/neg extracellular vesicles in plasma of humans at extreme altitude. PLoS ONE, 14(8), e0220133. Public Library of Science 10.1371/journal.pone.0220133

Gao, Yanyun; Dorn, Patrick; Liu, Shengchen; Deng, Haibin; Hall, Sean R. R.; Peng, Ren-Wang; Schmid, Ralph; Marti, Thomas M. (2019). Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer cell international, 19(317), p. 317. BioMed Central 10.1186/s12935-019-1037-1


Krag, Mette; Marker, Søren; Perner, Anders; Wetterslev, Jørn; Wise, Matt P; Schefold, Joerg C.; Keus, Frederik; Guttormsen, Anne B; Bendel, Stepani; Borthwick, Mark; Lange, Theis; Rasmussen, Bodil S; Siegemund, Martin; Bundgaard, Helle; Elkmann, Thomas; Jensen, Jacob V; Nielsen, Rune D; Liboriussen, Lisbeth; Bestle, Morten H; Elkjær, Jeanie M; ... (2018). Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU. The New England journal of medicine, 379(23), pp. 2199-2208. Massachusetts Medical Society 10.1056/NEJMoa1714919

Cooper, D James; Nichol, Alistair D; Bailey, Michael; Bernard, Stephen; Cameron, Peter A; Pili-Floury, Sébastien; Forbes, Andrew; Gantner, Dashiell; Higgins, Alisa M; Huet, Olivier; Kasza, Jessica; Murray, Lynne; Newby, Lynette; Presneill, Jeffrey J; Rashford, Stephen; Rosenfeld, Jeffrey V; Stephenson, Michael; Vallance, Shirley; Varma, Dinesh; Webb, Steven A R; ... (2018). Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial. JAMA : the journal of the American Medical Association, 320(21), pp. 2211-2220. American Medical Association 10.1001/jama.2018.17075

Bloch, Andreas; Glas, Michael; Kohler, Andreas; Baumann, Ulrich; Jakob, Stephan (2018). Non-Invasive Assessment of Intra-Abdominal Pressure Using Ultrasound Guided Tonometry - a Proof-of-Concept Study. Shock, 50(6), pp. 684-688. Lippincott Williams & Wilkins 10.1097/SHK.0000000000001085

Gorrasi, José Antonio; Jakob, Stephan; Tovar, Luis Antonio; Balsiger, Bruno Markus; Brandt, Sebastian; Brügger, Lukas; Bracht, Hendrik; Takala, Jukka (2018). Perioperative Fluid Accumulation Impairs Intestinal Contractility to a Smilar Extent as Peritonitis and Endotoxemia. Shock, 50(6), pp. 735-740. Lippincott Williams & Wilkins 10.1097/SHK.0000000000001088

Leite, Diogo Manuel Carvalho; Brochet, Xavier; Resch, Grégory; Que, Yok-Ai; Neves, Aitana; Peña-Reyes, Carlos (2018). Computational prediction of inter-species relationships through omics data analysis and machine learning. BMC bioinformatics, 19(Suppl 14), p. 420. BioMed Central 10.1186/s12859-018-2388-7

Künzli, Andrea Brigitte; Marschall, Jonas; Schefold, Joerg C.; Schafer, Margaret; Engler, Oliver B; Ackermann-Gäumann, Rahel; Reineke, David C; Suter, Franziska Marta; Staehelin, Cornelia (2018). Hantavirus Cardiopulmonary Syndrome Due to Imported Andes Hantavirus Infection in Switzerland: A Multidisciplinary Challenge, Two Cases and a Literature Review. Clinical infectious diseases, 67(11), pp. 1788-1795. Oxford Univ. Press 10.1093/cid/ciy443

Jent, Philipp; Trippel, Mafalda; Frey, Manuel; Pöllinger, Alexander; Berezowska, Sabina; Langer, Rupert; Furrer, Hansjakob; Béguelin, Charles Antoine (2018). Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient. Open Forum Infectious Diseases, 5(11), ofy244. Oxford University Press 10.1093/ofid/ofy244

Mårtensson, Johan; Bihari, Shailesh; Bannard-Smith, Jonathan; Glassford, Neil J; Lloyd-Donald, Patryck; Cioccari, Luca; Luethi, Nora; Tanaka, Aiko; Crisman, Marco; Rey de Castro, Nicolas; Ottochian, Marcus; Huang, Agnes; Cronhjort, Maria; Bersten, Andrew D; Prakash, Shivesh; Bailey, Michael; Eastwood, Glenn M; Bellomo, Rinaldo (2018). Small volume resuscitation with 20% albumin in intensive care: physiological effects : The SWIPE randomised clinical trial. Intensive care medicine, 44(11), pp. 1797-1806. Springer-Verlag 10.1007/s00134-018-5253-2

Cioccari, Luca; Zante, Bjoern; Bloch, Andreas; Berger, David; Limacher, Andreas; Jakob, Stephan M; Takala, Jukka; Merz, Tobias M (2018). Correction to: Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients - study protocol for a randomized controlled trial. [correction]. Trials, 19(1), p. 587. BioMed Central 10.1186/s13063-018-3001-0

von Wolff, M.; Nakas, Christos T.; Wolf, Marlene; Merz, Tobias; Hilty, M P; Veldhuis, J D; Huber, A R; Pichler Hefti, Jacqueline Renée (2018). Adrenal, thyroid and gonadal axes are affected at high altitude. Endocrine Connections, 7(10), pp. 1081-1089. BioScientifica 10.1530/EC-18-0242

Berger-Estilita, Joana; Passer, M.; Giles, M.; Wiegand, J.; Merz, Tobias (2018). Modalities and accuracy of diagnosis of external ventricular drainage-related infections: a prospective multicentre observational cohort study. Acta neurochirurgica, 160(10), pp. 2039-2047. Springer Vienna 10.1007/s00701-018-3643-4

Fournier, A; Eggimann, P; Pantet, O; Pagani, J L; Dupuis-Lozeron, E; Pannatier, A; Sadeghipour, F; Voirol, P; Que, Y.-A. (2018). Reply to Sorooshian and Snow, "Is Alternate-Day Therapeutic Drug Monitoring in the Intensive Care Unit Not Intensive Enough?". Antimicrobial agents and chemotherapy, 62(10) American Society for Microbiology 10.1128/AAC.01343-18

Pfeiffer, Christian; Nguissi, Nathalie Ata Nguepnjo; Chytiris, Magali; Bidlingmeyer, Phanie; Hänggi, Matthias; Kurmann, Rebekka; Zubler, Frédéric; Accolla, Ettore; Viceic, Dragana; Rusca, Marco; Oddo, Mauro; Rossetti, Andrea O; De Lucia, Marzia (2018). Somatosensory and auditory deviance detection for outcome prediction during postanoxic coma. Annals of Clinical and Translational Neurology, 5(9), pp. 1016-1024. Wiley 10.1002/acn3.600

Fournier, Anne; Goutelle, Sylvain; Que, Yok-Ai; Eggimann, Philippe; Pantet, Olivier; Sadeghipour, Farshid; Voirol, Pierre; Csajka, Chantal (2018). Population Pharmacokinetic Study of Amoxicillin-Treated Burn Patients Hospitalized at a Swiss Tertiary-Care Center. Antimicrobial agents and chemotherapy, 62(9) American Society for Microbiology 10.1128/AAC.00505-18

Moser, Michaela; Jeitziner, Marie-Madlen; Spichiger, Elisabeth (2018). [Anxiety during the chronic critical illness in the intensive care unit - an interpretive phenomenological study]. Pflege - die wissenschaftliche Zeitschrift für Pflegeberufe, 31(6), pp. 311-318. H. Huber 10.1024/1012-5302/a000643

Surial, Bernard; Atkinson, Andrew; Nüesch, Susanne; Schefold, Joerg C.; Marschall, Jonas (2018). Promoting an action plan for devices in the emergency department-does it impact catheter duration? Infection control and hospital epidemiology, 39(8), pp. 1011-1012. Cambridge University Press 10.1017/ice.2018.132

Bielecka-Dabrowa, Agata; Godoy, Breno; Schefold, Joerg C.; Koziolek, Michael; Banach, Maciej; von Haehling, Stephan (2018). Decompensated Heart Failure and Renal Failure: What Is the Current Evidence? Current heart failure reports, 15(4), pp. 224-238. Springer 10.1007/s11897-018-0397-5

Müller, Martin; Schefold, Joerg C.; Guignard, Viviane; Exadaktylos, Aristomenis; Pfortmüller, Carmen (2018). Hyponatraemia is independently associated with in-hospital mortality in patients with pneumonia. European journal of internal medicine, 54, pp. 46-52. Elsevier 10.1016/j.ejim.2018.04.008

Cioccari, Luca; Zante, Bjoern; Bloch, Andreas; Berger, David; Limacher, Andreas; Jakob, Stephan M; Takala, Jukka; Merz, Tobias M (2018). Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients - study protocol for a randomized controlled trial. Trials, 19(1), p. 362. BioMed Central 10.1186/s13063-018-2714-4

Guidet, Bertrand; Flaatten, Hans; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn H; Artigas, Antonio; Bertolini, Guido; Cecconi, Maurizio; Christensen, Steffen; Faraldi, Loredana; Fjølner, Jesper; Jung, Christian; Marsh, Brian; Moreno, Rui; Oeyen, Sandra; Öhman, Christina Agwald; Pinto, Bernardo Bollen; Soliman, Ivo W; Szczeklik, Wojciech; Valentin, Andreas; ... (2018). Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit. Intensive care medicine, 44(7), pp. 1027-1038. Springer 10.1007/s00134-018-5196-7

Collet, Marie O; Caballero, Jesús; Sonneville, Romain; Bozza, Fernando A; Nydahl, Peter; Schandl, Anna; Wøien, Hilden; Citerio, Giuseppe; van den Boogaard, Mark; Hästbacka, Johanna; Hänggi, Matthias; Colpaert, Kirsten; Rose, Louise; Barbateskovic, Marija; Lange, Theis; Jensen, Aksel; Krog, Martin B; Egerod, Ingrid; Nibro, Helle L; Wetterslev, Jørn; ... (2018). Prevalence and risk factors related to haloperidol use for delirium in adult intensive care patients: the multinational AID-ICU inception cohort study. Intensive care medicine, 44(7), pp. 1081-1089. Springer 10.1007/s00134-018-5204-y

Schefold, Joerg C.; Zürcher, Patrick; Takala, Jukka (2018). The authors reply. Critical care medicine, 46(7), e727-e728. Lippincott Williams & Wilkins 10.1097/CCM.0000000000003163

Zante, Björn; Hammel, Eva Margarete; Lauber, Arno; Schefold, Joerg C. (2018). 'Chasing the dragon' on the intensive care unit. Anaesthesiology intensive therapy, 50(3), p. 243. Via Medica 10.5603/AIT.a2018.0014

Putzu, Alessandro; Valtorta, Silvia; Di Grigoli, Giuseppe; Hänggi, Matthias; Belloli, Sara; Malgaroli, Antonio; Gemma, Marco; Landoni, Giovanni; Beretta, Luigi; Moresco, Rosa Maria (2018). Regional Differences in Cerebral Glucose Metabolism After Cardiac Arrest and Resuscitation in Rats Using [(18)F]FDG Positron Emission Tomography and Autoradiography. Neurocritical care, 28(3), pp. 370-378. Springer 10.1007/s12028-017-0445-0

Aneman, Anders; Brechot, Nicholas; Brodie, Daniel; Colreavy, Frances; Fraser, John; Gomersall, Charles; McCanny, Peter; Moller-Sorensen, Peter Hasse; Takala, Jukka; Valchanov, Kamen; Vallely, Michael (2018). Advances in critical care management of patients undergoing cardiac surgery. Intensive care medicine, 44(6), pp. 799-810. Springer-Verlag 10.1007/s00134-018-5182-0

Perner, Anders; Cecconi, Maurizio; Cronhjort, Maria; Darmon, Michael; Jakob, Stephan; Pettilä, Ville; van der Horst, Iwan C C (2018). Expert statement for the management of hypovolemia in sepsis. Intensive care medicine, 44(6), pp. 791-798. Springer-Verlag 10.1007/s00134-018-5177-x

Musy, Sarah N; Ausserhofer, Dietmar; Schwendimann, René; Rothen, Hans Ulrich; Jeitziner, Marie-Madlen; Rutjes, Anne; Simon, Michael (2018). Trigger Tool-Based Automated Adverse Event Detection in Electronic Health Records: Systematic Review. Journal of medical internet research, 20(5), e198. Centre of Global eHealth Innovation 10.2196/jmir.9901

Nebiker, Mathias; Frueh, Beatrice E; Tappeiner, Christoph (2018). Impact of changing the recruitment and interview procedures for cornea donation on the consent rate at a University hospital in Switzerland. (In Press). Transplant international Wiley-Blackwell 10.1111/tri.13278

Granholm, A; Lange, T; Anthon, C T; Marker, S; Krag, M; Meyhoff, T S; Wise, M P; Borthwick, M; Bendel, S; Keus, F; Guttormsen, A B; Schefold, Joerg C.; Wetterslev, J; Perner, A; Møller, M H (2018). Timing of onset of gastrointestinal bleeding in the ICU: Protocol for a preplanned observational study. (In Press). Acta anaesthesiologica Scandinavica Wiley-Blackwell 10.1111/aas.13144

Boërio, Delphine; Corrêa, Thiago D; Jakob, Stephan; Ackermann, Karin A; Bostock, Hugh; Z'Graggen, Werner Josef (2018). Muscle membrane properties in A pig sepsis model: Effect of norepinephrine. Muscle & nerve, 57(5), pp. 808-813. John Wiley & Sons 10.1002/mus.26013

Hireche-Chikaoui, Hanane; Grübler, Martin R; Bloch, Andreas; Windecker, Stephan; Blöchlinger, Stefan; Hunziker, Lukas (2018). Nonejecting Hearts on Femoral Veno-Arterial Extracorporeal Membrane Oxygenation: Aortic Root Blood Stasis and Thrombus Formation-A Case Series and Review of the Literature. Critical care medicine, 46(5), e459-e464. Wolters Kluwer Health 10.1097/CCM.0000000000002966

Eyeington, C T; Ancona, P; Cioccari, Luca; Luethi, N; Glassford, N J; Eastwood, G M; Proimos, H K; Franceschi, F; Chan, M J; Jones, D; Bellomo, R (2018). Non-invasive estimation of cardiac index in healthy volunteers. Anaesthesia and intensive care, 46(3), pp. 290-296. Australian Society of Anaesthetists

Vincent, Jean-Louis; Jaschinski, Ulrich; Wittebole, Xavier; Lefrant, Jean-Yves; Jakob, Stephan; Almekhlafi, Ghaleb A; Pellis, Tommaso; Tripathy, Swagata; Rubatto Birri, Paolo N; Sakr, Yasser (2018). Worldwide audit of blood transfusion practice in critically ill patients. Critical care, 22(1), p. 102. BioMed Central 10.1186/s13054-018-2018-9

Pfortmüller, Carmen; Uehlinger, Dominik; von Haehling, Stephan; Schefold, Joerg C. (2018). Serum chloride levels in critical illness-the hidden story. Intensive care medicine experimental, 6(1), p. 10. Springer 10.1186/s40635-018-0174-5

Pfortmüller, Carmen; Kabon, Barbara; Schefold, Joerg C.; Fleischmann, Edith (2018). Crystalloid fluid choice in the critically ill : Current knowledge and critical appraisal. Wiener klinische Wochenschrift, 130(7-8), pp. 273-282. Springer 10.1007/s00508-018-1327-y

Zürcher, Patrick; Takala, Jukka; Schefold, Joerg C. (2018). The authors reply. Critical care medicine, 46(4), e344-e345. Lippincott Williams & Wilkins 10.1097/CCM.0000000000002978

Müller, Martin; Khamis, Dana; Srivastava, David Shiva; Exadaktylos, Aristomenis; Pfortmüller, Carmen (2018). Understanding Refugees' Health. Seminars in neurology, 38(2), pp. 152-162. Thieme 10.1055/s-0038-1649337

Erdös, Gabor; Uehlinger, Dominik E; Kobel, Beatrice; Stucki, Monika Pia; Wiest, Roland; Stüber, Frank; Fankhauser, Niklaus; Jakob, Stephan; Schefold, Joerg C. (2018). Cerebral microembolism in the critically ill with acute kidney injury (COMET-AKI trial): study protocol for a randomized controlled clinical trial. Trials, 19(1), p. 189. BioMed Central 10.1186/s13063-018-2561-3

Waskowski, Jan; Ott, Daniel; Schefold, Joerg C. (2018). Cardiopulmonary resuscitation and intrathoracic renal ectopy. Intensive care medicine, 44(3), pp. 378-379. Springer 10.1007/s00134-017-4987-6

Bloch, Andreas; Tomaschett, Corina; Jakob, Stephan; Schwinghammer, Andreas; Schmid, Timo (2018). Compression sonography for non-invasive measurement of lower leg compartment pressure in an animal model. Injury - international journal of the care of the injured, 49(3), pp. 532-537. Elsevier 10.1016/j.injury.2017.11.036

Sommerstein, Rami; Merz, Tobias; Jakob, Stephan; Takala, Jukka; Marschall, Jonas (2018). Decontamination of Extracorporeal Membrane Oxygenator Devices With an Intensified Disinfection Protocol: How Strict Is Too Strict? Infection control and hospital epidemiology, 39(3), pp. 366-367. Cambridge University Press 10.1017/ice.2017.283

Fournier, A; Eggimann, P; Pantet, O; Pagani, J L; Dupuis-Lozeron, E; Pannatier, A; Sadeghipour, F; Voirol, P; Que, Yok-Ai (2018). Impact of Real-Time Therapeutic Drug Monitoring on the Prescription of Antibiotics in Burn Patients Requiring Admission to the Intensive Care Unit. Antimicrobial agents and chemotherapy, 62(3) American Society for Microbiology 10.1128/AAC.01818-17

Merz, Tobias (2018). One Score to Rule Them All? ICU Scoring at the Dawn of the Digital Age. Critical care medicine, 46(3), pp. 484-485. Wolters Kluwer Health 10.1097/CCM.0000000000002900

Vincent, Jean-Louis; Lefrant, Jean-Yves; Kotfis, Katarzyna; Nanchal, Rahul; Martin-Loeches, Ignacio; Wittebole, Xavier; Sakka, Samir G; Pickkers, Peter; Moreno, Rui; Sakr, Yasser (2018). Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP). Intensive care medicine, 44(3), pp. 337-344. Springer-Verlag 10.1007/s00134-017-5043-2

Gahl, Brigitta; Göber, Volkhard; Odutayo, Ayodele; Tevaearai Stahel, Hendrik T; Da Costa, Bruno R; Jakob, Stephan M; Fiedler, G Martin; Chan, Olivia; Carrel, Thierry P; Jüni, Peter (2018). Prognostic Value of Early Postoperative Troponin T in Patients Undergoing Coronary Artery Bypass Grafting. Journal of the American Heart Association, 7(5), e007743. American Heart Association 10.1161/JAHA.117.007743

Aregger, Fabienne; Uehlinger, Dominik; Fusch, Gerhard; Bahonjic, Aldin; Pschowski, Rene; Walter, Michael; Schefold, Joerg C. (2018). Increased urinary excretion of kynurenic acid is associated with non-recovery from acute kidney injury in critically ill patients. BMC nephrology, 19(1), p. 44. BioMed Central 10.1186/s12882-018-0841-5

Glas, Michael; Frick, Tamara; Springe, Dirk; Putzu, Alessandro; Zürcher, Patrick; Grandgirard, Denis; Leib, Stephen; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2018). Neuroprotection with the P53-Inhibitor Pifithrin-μ After Cardiac Arrest in a Rodent Model. Shock, 49(2), pp. 229-234. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000917

Müller, Sabine; Nussbaumer, Susanne; Plitzko, Gabriel; Ludwig, Roger; Weinmann, Wolfgang; Krähenbühl, Stephan; Liakoni, Evangelia (2018). Recreational use of carfentanil - a case report with laboratory confirmation. Clinical toxicology, 56(2), pp. 151-152. Taylor & Francis 10.1080/15563650.2017.1355464

Oweira, H; Lahdou, I; Opelz, G; Daniel, V; Terness, P; Schmidt, J; Mehrabi, A; Fusch, G; Schefold, Joerg C.; Zidan, A; Sadeghi, M (2018). Association of pre- and early post-transplant serum amino acids and metabolites of amino acids and liver transplant outcome. Transplant immunology, 46, pp. 42-48. Elsevier 10.1016/j.trim.2017.12.003

Schefold, Joerg C.; Perner, Anders; Lange, Theis; Wetterslev, Jørn; Wise, Matt P; Borthwick, Mark; Bendel, Stepani; Keus, Frederik; Guttormsen, Anne Berit; Marker, Søren; Krag, Mette; Møller, Morten Hylander (2018). Effects of stress ulcer prophylaxis in adult ICU patients receiving renal replacement therapy (Sup-Icu RENal, SIREN): Study protocol for a pre-planned observational study. Trials, 19(1), p. 26. BioMed Central 10.1186/s13063-017-2408-3

Zante, Björn; Stoecklin, Patricia Gabrielle; Schefold, Joerg C. (2018). Journal Club sessions in the Intensive Care Unit: a conceptual framework. Anaesthesiology intensive therapy, 50(1), pp. 7-10. Via Medica 10.5603/AIT.a2018.0001

Blissenbach, Birgit; Nakas, Christos T.; Krönke, Martin; Geiser, Thomas; Merz, Tobias; Pichler Hefti, Jacqueline Renée (2018). Hypoxia-induced changes in plasma microRNAs correlate with pulmonary artery pressure at high altitude. American journal of physiology - lung cellular and molecular physiology, 314(1), L157-L164. American Physiological Society 10.1152/ajplung.00146.2017

Gonzalez, Manuel R.; Ducret, Verena; Leoni, Sara; Fleuchot, Betty; Jafari, Paris; Raffoul, Wassim; Applegate, Lee A.; Que, Yok-Ai; Perron, Karl (2018). Transcriptome analysis of Pseudomonas aeruginosa cultured in human burn wound exudates. Frontiers in cellular and infection microbiology, 8(39), p. 39. Frontiers 10.3389/fcimb.2018.00039

Bloch, Andreas; Schai, Nadja; Friess, Jan-Oliver; Merz, Tobias; Erdös, Gabor (2018). ECPR in a tertiary care hospital: Presentation of challenges on the basis of a real case. Trends in Anaesthesia and Critical Care, 21, pp. 27-32. Elsevier 10.1016/j.tacc.2018.04.005

Erdös, Gabor; Dietrich, Wulf; Stucki, Monika Pia; Merz, Tobias Michael; Angelillo, Anne; Nagler, Michael; Carrel, Thierry; Eberle, Balthasar (2018). Short-term recovery pattern of plasma fibrinogen after cardiac surgery: A prospective observational study. PLoS ONE, 13(8), e0201647. Public Library of Science 10.1371/journal.pone.0201647

Zante, Björn; Reichenspurner, Hermann; Kubik, Mathias; Kluge, Stefan; Schefold, Joerg C.; Pfortmüller, Carmen (2018). Base excess is superior to lactate-levels in prediction of ICU mortality after cardiac surgery. PLoS ONE, 13(10), e0205309. Public Library of Science 10.1371/journal.pone.0205309

Heldner, Mirjam Rachel; Jung, Simon; Fischer, Urs; Hänggi, Matthias; Z'Graggen, Werner Josef; Arnold, Marcel (2018). Akuter ischämischer Hirnschlag. Swiss Medical Forum, 18(3031), pp. 611-617. EMH Swiss Medical Publishers 10.4414/smf.2018.03334

Berger, David; Takala, Jukka (2018). Determinants of systemic venous return and the impact of positive pressure ventilation. Annals of translational medicine, 6(18), p. 350. AME Publishing Company 10.21037/atm.2018.05.27

Mancini, Stefano; Oechslin, Frank; Menzi, Carmen; Que, Yok Ai; Claes, Jorien; Heying, Ruth; Veloso, Tiago Rafael; Vanassche, Thomas; Missiakas, Dominique; Schneewind, Olaf; Moreillon, Philippe; Entenza, José Manuel (2018). Marginal role of von Willebrand factor-binding protein and coagulase in the initiation of endocarditis in rats with catheter-induced aortic vegetations. Virulence, 9(1), pp. 1615-1624. Taylor & Francis 10.1080/21505594.2018.1528845

Eggmann, Sabrina; Verra, Martin L.; Luder, Gere; Takala, Jukka; Jakob, Stephan (2018). Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: A randomised controlled trial. PLoS ONE, 13(11), e0207428. Public Library of Science 10.1371/journal.pone.0207428

Setzer, Florian; Schmidt, Barbara; Hueter, Lars; Schwarzkopf, Konrad; Sänger, Jörg; Schreiber, Torsten (2018). Characterization of the seven-day course of pulmonary response following unilateral lung acid injury in rats. PLoS ONE, 13(6), e0198440. Public Library of Science 10.1371/journal.pone.0198440


Myhre, Peder Langeland; Stridsberg, Mats; Linko, Rita; Okkonen, Marjatta; Nygård, Ståle; Christensen, Geir; Pettilä, Ville Yrjö Olavi; Omland, Torbjørn; Røsjø, Helge (2017). Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study. Biomarkers, 22(8), pp. 775-781. Taylor & Francis 10.1080/1354750X.2016.1269200

Hilty, Matthias Peter; Pichler Hefti, Jacqueline Renée; Ergin, Bulent; Hefti, Urs; Merz, Tobias; Ince, Can; Maggiorini, Marco (2017). Assessment of endothelial cell function and physiological microcirculatory reserve by video microscopy using a topical acetylcholine and nitroglycerin challenge. Intensive care medicine experimental, 5(1), p. 26. Springer 10.1186/s40635-017-0139-0

Pfortmüller, Carmen; Schefold, Joerg C. (2017). Hypertonic saline in critical illness - A systematic review. Journal of critical care, 42, pp. 168-177. Elsevier 10.1016/j.jcrc.2017.06.019

Schefold, Joerg C.; Berger, David; Zürcher, Patrick; Lensch, Michael; Perren, Andrea; Jakob, Stephan; Parviainen, Ilkka; Takala, Jukka (2017). Dysphagia in Mechanically Ventilated ICU Patients (DYnAMICS): A Prospective Observational Trial. Critical care medicine, 45(12), pp. 2061-2069. Lippincott Williams & Wilkins 10.1097/CCM.0000000000002765

Shehabi, Yahya; Forbes, Andrew B; Arabi, Yaseen; Bass, Frances; Bellomo, Rinaldo; Kadiman, Suhaini; Howe, Belinda D; McArthur, Colin; Reade, Michael C; Seppelt, Ian; Takala, Jukka; Webb, Steve; Wise, Matthew P (2017). The SPICE III study protocol and analysis plan: a randomised trial of early goaldirected sedation compared with standard care in mechanically ventilated patients. Critical care and resuscitation, 19(4), pp. 318-326. College of Intensive Care Medicine of Australia and New Zealand

Jakob, Stephan; Takala, Jukka (2017). Subcellular Energetics and Metabolism: A Cross-Species Framework. Anesthesia and analgesia, 125(6), p. 2160. Lippincott Williams & Wilkins 10.1213/ANE.0000000000002476

Bauer, Philippe R; Gajic, Ognjen; Nanchal, Rahul; Kashyap, Rahul; Martin-Loeches, Ignacio; Sakr, Yasser; Jakob, Stephan; François, Bruno; Wittebole, Xavier; Wunderink, Richard G; Vincent, Jean-Louis (2017). Association between timing of intubation and outcome in critically ill patients: A secondary analysis of the ICON audit. Journal of critical care, 42, pp. 1-5. Elsevier 10.1016/j.jcrc.2017.06.010

Mazer, C David; Whitlock, Richard P; Fergusson, Dean A; Hall, Judith; Belley-Cote, Emilie; Connolly, Katherine; Khanykin, Boris; Gregory, Alexander J; de Médicis, Étienne; McGuinness, Shay; Royse, Alistair; Carrier, François M; Young, Paul J; Villar, Juan C; Grocott, Hilary P; Seeberger, Manfred D; Fremes, Stephen; Lellouche, François; Syed, Summer; Byrne, Kelly; ... (2017). Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery. New England journal of medicine NEJM, 377(22), pp. 2133-2144. Massachusetts Medical Society MMS 10.1056/NEJMoa1711818

Pfortmüller, Carmen; Meisel, Christian; Fux, Michaela; Schefold, Joerg C. (2017). Assessment of immune organ dysfunction in critical illness: utility of innate immune response markers. Intensive care medicine experimental, 5(1), p. 49. Springer 10.1186/s40635-017-0163-0

Gerber, Stephan Moreno; Jeitziner, Marie-Madlen; Wyss, Patric; Chesham, Alvin; Urwyler, Prabitha; Müri, René Martin; Jakob, Stephan; Nef, Tobias (2017). Visuo-acoustic stimulation that helps you to relax: A virtual reality setup for patients in the intensive care unit. Scientific Reports, 7(1), pp. 1-10. Nature Publishing Group 10.1038/s41598-017-13153-1

Bloch, Andreas; Von Arx, Robert; Etter, Reto; Berger, David; Kaiser, Heiko; Lenz, Armando; Merz, Tobias (2017). Impact of Simulator-Based Training in Focused Transesophageal Echocardiography: A Randomized Controlled Trial. Anesthesia and analgesia, 125(4), pp. 1140-1148. Lippincott Williams & Wilkins 10.1213/ANE.0000000000002351

Pfortmüller, Carmen; Meisel, Christian; Schefold, Joerg C. (2017). Interpreting Immune Mediator Dysbalance in Sepsis. Critical care medicine, 45(10), e1094-e1095. Lippincott Williams & Wilkins 10.1097/CCM.0000000000002547

Vahtera, Annukka; Valkonen, Miia; Huhtala, Heini; Pettilä, Ville Yrjö Olavi; Kuitunen, Anne (2017). Plasma anti-FXa concentration after continuous intravenous infusion and subcutaneous dosing of enoxaparin for thromboprophylaxis in critically ill patients. A randomized clinical trial. Thrombosis research, 158, pp. 71-75. Elsevier 10.1016/j.thromres.2017.08.014

Grübler, Martin R; Wigger, Olivier; Berger, David; Blöchlinger, Stefan (2017). Basic concepts of heart-lung interactions during mechanical ventilation. Swiss medical weekly, 147(w14491), w14491. EMH Schweizerischer Ärzteverlag 10.4414/smw.2017.14491

Scherbakov, Nadja; Sandek, Anja; Ebner, Nicole; Valentova, Miroslava; Nave, Alexander Heinrich; Jankowska, Ewa A; Schefold, Joerg C.; von Haehling, Stephan; Anker, Stefan D; Fietze, Ingo; Fiebach, Jochen B; Haeusler, Karl Georg; Doehner, Wolfram (2017). Sleep-Disordered Breathing in Acute Ischemic Stroke: A Mechanistic Link to Peripheral Endothelial Dysfunction. Journal of the American Heart Association, 6(9) American Heart Association 10.1161/JAHA.117.006010

Pfeiffer, Christian; Nguissi, Nathalie Ata Nguepno; Chytiris, Magali; Bidlingmeyer, Phanie; Hänggi, Matthias; Kurmann, Rebekka; Zubler, Frédéric; Oddo, Mauro; Rossetti, Andrea O; De Lucia, Marzia (2017). Auditory discrimination improvement predicts awakening of postanoxic comatose patients treated with targeted temperature management at 36°C. Resuscitation, 118, pp. 89-95. Elsevier Science Ireland 10.1016/j.resuscitation.2017.07.012

Zante, Björn; Happ, Sebastian; Haltmeier, Tobias; Schefold, Joerg C. (2017). Aerosplenism in the intensive care unit. Anaesthesiology intensive therapy, 49(3), pp. 243-244. Via Medica 10.5603/AIT.a2017.0037

Werner Möller, Per; Winkler, Berhard; Hurni, Samuel; Heinisch, Paul Philipp; Bloch, Andreas; Sondergaard, Soren; Jakob, Stephan; Takala, Jukka; Berger, David (2017). Right atrial pressure and venous return during cardiopulmonary bypass. American journal of physiology - heart and circulatory physiology, 313(2), H408-H420. American Physiological Society 10.1152/ajpheart.00081.2017

Krag, M; Perner, A; Wetterslev, J; Lange, T; Wise, M P; Borthwick, M; Bendel, S; Pelosi, P; Keus, F; Guttormsen, A B; Schefold, Joerg C.; Meyhoff, T S; Marker, S; Møller, M H (2017). Stress ulcer prophylaxis in the intensive care unit trial: detailed statistical analysis plan. Acta anaesthesiologica Scandinavica, 61(7), pp. 859-868. Wiley-Blackwell 10.1111/aas.12917

Bloch, Andreas; Kohler, Andreas; Posthaus, Horst; Berger, David; Santos, Laura; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2017). Gastrointestinal Impedance Spectroscopy to Detect Hypoperfusion During Hemorrhage. Shock, 48(2), pp. 185-195. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000824

Lobo, Suzana M; De Simoni, Flávio H B; Jakob, Stephan; Estella, Angel; Vadi, Sonali; Bluethgen, Andreas; Martin-Loeches, Ignacio; Sakr, Yasser; Vincent, Jean-Louis (2017). Decision-Making on Withholding or Withdrawing Life Support in the ICU: A Worldwide Perspective. Chest, 152(2), pp. 321-329. American College of Chest Physicians 10.1016/j.chest.2017.04.176

Storm, Christian; Nee, J; Sunde, Kjetil; Holzer, Michael; Hubner, Pia; Taccone, Fabio Silvio; Friberg, Hans; Lopez-de-Sa, Esteban; Cariou, Alain; Schefold, Joerg C.; Ristagno, Giuseppe; Noc, Marko; Donker, Dirk W; Andres, Janusz; Krawczyk, Pawel; Skrifvars, Markus B; Penketh, James; Krannich, Alexander; Fries, Michael (2017). A survey on general and temperature management of post cardiac arrest patients in large teaching and university hospitals in 14 European countries-The SPAME trial results. Resuscitation, 116, pp. 84-90. Elsevier Science Ireland 10.1016/j.resuscitation.2017.03.038

Vignon, Philippe; Merz, Tobias; Vieillard-Baron, Antoine (2017). Ten reasons for performing hemodynamic monitoring using transesophageal echocardiography. Intensive care medicine, 43(7), pp. 1048-1051. Springer 10.1007/s00134-017-4716-1

Bär, Sarah; Daudel, Fritz; Züger, Thomas (2017). Ominous triad triggered by high-dose glucocorticosteroid therapy. BMJ case reports, 2017 BMJ Publishing Group 10.1136/bcr-2017-220328

Jakob, Stephan M; Bütikofer, Lukas; Berger, David; Coslovsky, Michael; Takala, Jukka (2017). A randomized controlled pilot study to evaluate the effect of an enteral formulation designed to improve gastrointestinal tolerance in the critically ill patient-the SPIRIT trial. Critical care, 21(1), p. 140. BioMed Central 10.1186/s13054-017-1730-1

Ollila, Aino; Virolainen, Juha; Vanhatalo, Joonas; Vikatmaa, Pirkka; Tikkanen, Ilkka; Venermo, Maarit; Salmenperä, Markku; Pettilä, Ville Yrjö Olavi; Vikatmaa, Leena (2017). Postoperative Cardiac Ischemia Detection by Continuous 12-Lead Electrocardiographic Monitoring in Vascular Surgery Patients: A Prospective, Observational Study. Journal of cardiothoracic and vascular anesthesia, 31(3), pp. 950-956. Elsevier 10.1053/j.jvca.2016.09.027

De Marchis, Gian Marco; Schaad, Chris; Fung, Christian; Beck, Jürgen; Gralla, Jan; Takala, Jukka; Jakob, Stephan (2017). Gender-related differences in aneurysmal subarachnoid hemorrhage: A hospital based study. Clinical neurology and neurosurgery, 157, pp. 82-87. Elsevier 10.1016/j.clineuro.2017.04.009

Corrêa, Thiago Domingos; Pereira, Adriano José; Brandt, Sebastian; Vuda, Madhusudanarao; Djafarzadeh, Siamak; Takala, Jukka; Jakob, Stephan (2017). Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis. Critical care, 21(1), p. 105. BioMed Central 10.1186/s13054-017-1691-4

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Zante, Björn; Schefold, Joerg C.; Nelson, Judith E; Edwards, Jeffrey D; Voigt, Louis P (2017). One ring to rule them all: education in ICU palliative care : Discussion on "Ten key points about ICU palliative care". Intensive care medicine, 43(5), pp. 720-721. Springer 10.1007/s00134-017-4719-y

Sendi, Parham; Hirzel, Cédric; Bloch, Andreas; Fischer, Urs; Jeannet, Natalie; Berlinger, Livia; Krestel, Heinz Eric (2017). Bartonella-Associated Transverse Myelitis. Emerging infectious diseases, 23(4), pp. 712-713. U.S. National Center for Infectious Diseases 10.3201/eid2304.161733

Jakob, Stephan; Takala, Jukka (2017). Comments on Teboul and Scheeren: understanding the Haldane effect. Intensive care medicine, 43(4), p. 597. Springer 10.1007/s00134-017-4697-0

Berger, David; Werner Möller, Per; Blöchlinger, Stefan; Bloch, Andreas; Jakob, Stephan; Takala, Jukka (21 March 2017). P106 Methodological issues for the determination of mean systemic filling pressure at the end of life. Critical care, 21(Suppl1), p. 41. BioMed Central

Werner Möller, Per; Jakob, Stephan; Takala, Jukka; Berger, David (21 March 2017). P108 Right atrial pressure as back-pressure to venous return. Critical care, 21(Suppl 1), pp. 41-42. BioMed Central

Vilander, Laura M; Kaunisto, Mari A; Vaara, Suvi T; Pettilä, Ville Yrjö Olavi (2017). Genetic variants in SERPINA4 and SERPINA5, but not BCL2 and SIK3 are associated with acute kidney injury in critically ill patients with septic shock. Critical care, 21(1), p. 47. BioMed Central 10.1186/s13054-017-1631-3

Djafarzadeh, Siamak; Jakob, Stephan (2017). Isolation of Intact Mitochondria from Skeletal Muscle by Differential Centrifugation for High-resolution Respirometry Measurements. Journal of visualized experiments(121) MYJoVE Corporation 10.3791/55251

Fournier, A; Voirol, P; Krähenbühl, M; Bonnemain, C-L; Fournier, C; Dupuis-Lozeron, E; Pantet, O; Pagani, J-L; Revelly, J-P; Sadeghipour, F; Eggimann, P; Que, Yok-Ai (2017). Staphylococcus aureus carriage at admission predicts early-onset pneumonia after burn trauma. European journal of clinical microbiology & infectious diseases, 36(3), pp. 523-528. Springer 10.1007/s10096-016-2828-0

Andereggen, Lukas; Beck, Jürgen; Z'Graggen, Werner Josef; Schroth, Gerhard; Andres, R H; Murek, Michael; Hänggi, Matthias; Reinert, M; Raabe, Andreas; Gralla, Jan (2017). Feasibility and Safety of Repeat Instant Endovascular Interventions in Patients with Refractory Cerebral Vasospasms. AJNR. American journal of neuroradiology, 38(3), pp. 561-567. American Society of Neuroradiology 10.3174/ajnr.A5024

Sakr, Yasser; Rubatto Birri, Paolo Nahuel; Kotfis, Katarzyna; Nanchal, Rahul; Shah, Bhagyesh; Kluge, Stefan; Schroeder, Mary E; Marshall, John C; Vincent, Jean-Louis (2017). Higher Fluid Balance Increases the Risk of Death From Sepsis: Results From a Large International Audit. Critical care medicine, 45(3), pp. 386-394. Lippincott Williams & Wilkins 10.1097/CCM.0000000000002189

Djafarzadeh, Siamak; Jakob, Stephan (2017). High-resolution Respirometry to Assess Mitochondrial Function in Permeabilized and Intact Cells. Journal of visualized experiments(120) MYJoVE Corporation 10.3791/54985

Jeannet, Natalie; van den Hoogen, Bernadette G; Schefold, Joerg C.; Suter, Franziska Marta; Sommerstein, Rami (2017). Cerebrospinal Fluid Findings in an Adult with Human Metapneumovirus-Associated Encephalitis. Emerging infectious diseases, 23(2), p. 370. U.S. National Center for Infectious Diseases 10.3201/eid2302.161337

Vavricka, Stephan; Ruiz, Pedro A; Scharl, Sylvie; Biedermann, Luc; Scharl, Michael; de Vallière, Cheryl; Lundby, Carsten; Wenger, Roland H; Held, Leonhard; Merz, Tobias; Gassmann, Max; Lutz, Thomas; Kunz, Andres; Bron, Denis; Fontana, Adriano; Strauss, Laura; Weber, Achim; Fried, Michael; Rogler, Gerhard and Zeitz, Jonas (2017). Protocol for a prospective, controlled, observational study to evaluate the influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease: the Altitude IBD Study. BMJ open, 7(1), e013477. BMJ Publishing Group 10.1136/bmjopen-2016-013477

Varis, Elina; Pettilä, Ville Yrjö Olavi; Poukkanen, Meri; Jakob, Stephan; Karlsson, Sari; Perner, Anders; Takala, Jukka; Wilkman, Erika (2017). Evolution of Blood Lactate and 90-Day Mortality in Septic Shock. A Post Hoc Analysis of the Finnaki Study. Shock, 47(5), pp. 574-581. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000772

Pschowski, Rene; Pape, Ulrich-Frank; Fusch, Gerhard; Fischer, Christian; Jann, Henning; Baur, Alexander; Arsenic, Ruza; Wiedenmann, Bertram; von Haehling, Stephan; Pavel, Marianne; Schefold, Joerg C. (2017). Increased Activity of the Immunoregulatory Enzyme Indoleamine-2,3-Dioxygenase (IDO) with Consecutive Tryptophan Depletion Predicts Death in Patients with Neuroendocrine Neoplasia. Neuroendocrinology, 104(2), pp. 135-144. Karger 10.1159/000445191

Shlezinger, Mor; Houri-Haddad, Yael; Coppenhagen-Glazer, Shunit; Resch, Grégory; Que, Yok-Ai; Beyth, Shaul; Dorfman, Elisheva; Hazan, Ronen; Beyth, Nurit (2017). Phage therapy: A new horizon in the antibacterial treatment of oral pathogens. Current topics in medicinal chemistry, 17(10), pp. 1199-1211. Bentham Science Publishers

Brander, Lukas; Moerer, Onnen; Hedenstierna, Göran; Beck, Jennifer; Takala, Jukka; Slutsky, Arthur S; Sinderby, Christer (2017). NEURAL CONTROL OF VENTILATION PREVENTS BOTH OVER-DISTENSION AND DE-RECRUITMENT OF EXPERIMENTALLY INJURED LUNGS. Respiratory physiology & neurobiology, 237, pp. 57-67. Elsevier 10.1016/j.resp.2016.12.010

Reintam Blaser, Annika; Starkopf, Joel; Alhazzani, Waleed; Berger, Mette M.; Casaer, Michael P.; Deane, Adam M.; Fruhwald, Sonja; Hiesmayr, Michael; Ichai, Carole; Jakob, Stephan; Loudet, Cecilia I.; Malbrain, Manu L. N. G.; Montejo González, Juan C.; Paugam-Burtz, Catherine; Poeze, Martijn; Preiser, Jean-Charles; Singer, Pierre; van Zanten, Arthur R.H.; De Waele, Jan; Wendon, Julia; ... (2017). Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines. Intensive care medicine, 43(3), pp. 380-398. Springer 10.1007/s00134-016-4665-0

Berger, David; Schefold, Joerg C. (2017). Life ain’t no SOFA—considerations after yet another failed clinical sepsis trial. Journal of thoracic disease, 9(3), pp. 438-440. Pioneer Bioscience Publishing 10.21037/jtd.2017.02.68

Rothen, Hans Ulrich; Jeitziner, Marie-Madlen (2017). Blick in die Schweiz: Peer Review - interprofessionell und mehrsprachig. In: Handbuch IQM (pp. 129-136). MWV Medizinisch Wissenschaftliche Verlagsgesellschaft

Merz, Tobias; Pereira, Adriano J; Schürch, Roger; Schefold, Joerg C.; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2017). Mitochondrial function of immune cells in septic shock: A prospective observational cohort study. PLoS ONE, 12(6), e0178946. Public Library of Science 10.1371/journal.pone.0178946

Zürcher, Patrick; Gerber, Daniel; Schai, Nadia; Nebiker, Mathias; König, Stefan; Schefold, Joerg C. (2017). Calypso's spell: accidental near-fatal thiacloprid intoxication. Clinical case reports, 5(10), pp. 1672-1675. Wiley 10.1002/ccr3.1146

Kessler, Ulf; Schlapbach, Luregn J.; Klimek, Peter Michael; Jakob, Stephan (2017). Low L-Ficolin associated with disease severity during sepsis in adult ICU patients. Liver international, 37(9), p. 1409. Blackwell Munksgaard 10.1111/liv.13448

Müller, Martin; Guignard, Viviane; Schefold, Joerg C.; Leichtle, Alexander Benedikt; Exadaktylos, Aristomenis; Pfortmüller, Carmen (2017). Utility of quick sepsis-related organ failure assessment (qSOFA) to predict outcome in patients with pneumonia. PLoS ONE, 12(12), e0188913. Public Library of Science 10.1371/journal.pone.0188913

Malinka, Thomas; Zerkowski, Jens Alexander; Borbély, Yves Michael; Nett, Philipp C.; Kröll, Dino (2017). Three-year outcomes of revisional laparoscopic Gastric Bypass after failed laparoscopic Sleeve: A case-matched analysis (Unpublished). In: IFSO. London. 29.8.-2.9.2017.


Konishi, Masaaki; Ebner, Nicole; Springer, Jochen; Schefold, Joerg C.; Doehner, Wolfram; Dschietzig, Thomas Bernd; Anker, Stefan D; von Haehling, Stephan (2016). Impact of Plasma Kynurenine Level on Functional Capacity and Outcome in Heart Failure - Results From Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF). Circulation journal, 81(1), pp. 52-61. Japanese Circulation Society 10.1253/circj.CJ-16-0791

Oechslin, Frank; Piccardi, Philippe; Mancini, Stefano; Gabard, Jérôme; Moreillon, Philippe; Entenza, José M; Resch, Gregory; Que, Yok-Ai (2016). Synergistic interaction between phage therapy and antibiotics clears Pseudomonas aeruginosa infection in endocarditis and reduces virulence. Journal of infectious diseases, 215(5), pp. 703-712. Oxford University Press 10.1093/infdis/jiw632

Mildh, Henriikka; Pettilä, Ville Yrjö Olavi; Korhonen, Anna-Maija; Karlsson, Sari; Ala-Kokko, Tero; Reinikainen, Matti; Vaara, Suvi T; FINNAKI, Study Group (2016). Three-year mortality in 30-day survivors of critical care with acute kidney injury: data from the prospective observational FINNAKI study. Annals of intensive care, 6(118), p. 118. Springer 10.1186/s13613-016-0218-5

Bloch, Andreas; Berger, David; Takala, Jukka (2016). Understanding circulatory failure in sepsis. Intensive care medicine, 42(12), pp. 2077-2079. Springer 10.1007/s00134-016-4514-1

Glas, Michael; Bauer, Janine Viola; Eichler, Hermann; Volk, Thomas (2016). Impedance aggregometric analysis of platelet function of apheresis platelet concentrates as a function of storage time. Scandinavian journal of clinical and laboratory investigation, 76(8), pp. 664-670. Taylor & Francis 10.1080/00365513.2016.1238505

Albrecht, Frederic W; Glas, Michael; Rensing, Hauke; Kindgen-Milles, Detlef; Volk, Thomas; Mathes, Alexander M (2016). A change of colloid from hydroxyethyl starch to gelatin does not reduce rate of renal failure or mortality in surgical critical care patients: Results of a retrospective cohort study. Journal of critical care, 36, pp. 160-165. Elsevier 10.1016/j.jcrc.2016.07.005

Wigger, Olivier; Blöchlinger, Stefan; Berger, David; Häner, Jonas Dominik; Zanchin, T; Windecker, Stephan; Räber, Lorenz; Schefold, Joerg C. (2016). Baseline serum bicarbonate levels independently predict short-term mortality in critically ill patients with ischaemic cardiogenic shock. European Heart Journal: Acute Cardiovascular Care, 7(1), pp. 45-52. Sage 10.1177/2048872616683526

Kirkegaard, Hans; Pedersen, Asger Roer; Pettilä, Ville Yrjö Olavi; Hjort, Jakob; Rasmussen, Bodil Steen; de Haas, Inge; Nielsen, Jørgen Feldbæk; Ilkjær, Susanne; Kaltoft, Anne; Jeppesen, Anni Nørgaard; Grejs, Anders Morten; Duez, Christophe Henri Valdemar; Larsen, Alf Inge; Toome, Valdo; Arus, Urmet; Taccone, Fabio Silvio; Storm, Christian; Laitio, Timo; Skrifvars, Markus B and Søreide, Eldar (2016). A statistical analysis protocol for the time-differentiated target temperature management after out-of-hospital cardiac arrest (TTH48) clinical trial. Scandinavian journal of trauma, resuscitation and emergency medicine, 24(1), p. 138. BioMed Central 10.1186/s13049-016-0334-0

Nobile, Leda; Taccone, Fabio S; Szakmany, Tamas; Sakr, Yasser; Jakob, Stephan; Pellis, Tommaso; Antonelli, Massimo; Leone, Marc; Wittebole, Xavier; Pickkers, Peter; Vincent, Jean-Louis (2016). The impact of extracerebral organ failure on outcome of patients after cardiac arrest: an observational study from the ICON database. Critical care, 20(1), p. 368. BioMed Central 10.1186/s13054-016-1528-6

Bhaskar, Monica; Jakob, Stephan; Djafarzadeh, Siamak (2 November 2016). Effect of cytomix and sedative drugs on mitochondrial electron transport chain of cultured primary human astrocytes (Unpublished). In: Day of Clinical Research 2016.

Bekfani, Tarek; Pellicori, Pierpaolo; Morris, Daniel A; Ebner, Nicole; Valentova, Miroslava; Steinbeck, Lisa; Wachter, Rolf; Elsner, Sebastian; Sliziuk, Veronika; Schefold, Joerg C.; Sandek, Anja; Doehner, Wolfram; Cleland, John G; Lainscak, Mitja; Anker, Stefan D; von Haehling, Stephan (2016). Sarcopenia in patients with heart failure with preserved ejection fraction: Impact on muscle strength, exercise capacity and quality of life. International journal of cardiology, 222, pp. 41-46. Elsevier 10.1016/j.ijcard.2016.07.135

Schefold, Joerg C. (2016). Renal replacement therapy modalities in the ICU: the continuity is intermittent. Intensive care medicine, 42(11), pp. 1838-1839. Springer 10.1007/s00134-016-4459-4

Habedank, Dirk; Schefold, Joerg C.; Bernhardt, Carolin; Karhausen, Tim; Doehner, Wolfram; Anker, Stefan D; Reinke, Petra (2016). Vasodilation and Exercise Capacity in Patients with End-Stage Renal Disease: A Prospective Proof-of-Concept Study. Cardiorenal medicine, 7(1), pp. 50-59. Karger 10.1159/000449174

Pettilä, Ville Yrjö Olavi; Jakob, Stephan; Takala, Jukka (2016). The new sepsis/septic shock-3 definition is just not enough - more detailed research is needed. Acta anaesthesiologica Scandinavica, 60(10), pp. 1344-1346. Wiley-Blackwell 10.1111/aas.12777

Schefold, Joerg C.; Filippatos, Gerasimos; Hasenfuss, Gerd; Anker, Stefan D; von Haehling, Stephan (2016). Heart failure and kidney dysfunction: epidemiology, mechanisms and management. Nature reviews. Nephrology, 12(10), pp. 610-623. Nature Publishing Group 10.1038/nrneph.2016.113

Schefold, Joerg C.; Fritschi, Nora; Fusch, Gerhard; Bahonjic, Aldin; Doehner, Wolfram; von Haehling, Stephan; Pschowski, Rene; Storm, Christian; Schroeder, Tim (2016). Influence of core body temperature on Tryptophan metabolism, kynurenines, and estimated IDO activity in critically ill patients receiving target temperature management following cardiac arrest. Resuscitation, 107, pp. 107-114. Elsevier Science Ireland 10.1016/j.resuscitation.2016.07.239

Zante, Björn; Schefold, Joerg C. (2016). Ave CAESAR: at the end of life in the intensive care unit. Intensive care medicine, 42(10), pp. 1651-1652. Springer 10.1007/s00134-016-4450-0

Carrel, Thierry; Englberger, Lars; Takala, Jukka (2016). What's new in surgical treatment of infective endocarditis? Intensive care medicine, 42(12), pp. 2052-2054. Springer 10.1007/s00134-016-4542-x

Hallak, Ghias; Neuner, Bruno; Schefold, Joerg C.; Gorzelniak, Kerstin; Rapsch, Brigitte; Pfüller, Roland; Stengel, Dirk; Wellmann, Jürgen; Ekkernkamp, Axel; Walter, Michael (2016). Preemptive Isolation Precautions of Patients at High Risk for Methicillin-Resistant Staphylococcus aureus in Combination With Ultrarapid Polymerase Chain Reaction Screening as an Effective Tool for Infection Control. Infection control and hospital epidemiology, 37(12), pp. 1489-1491. Cambridge University Press 10.1017/ice.2016.204

Tissot, F; Blanc, D S; Basset, P; Zanetti, G; Berger, M M; Que, Yok-Ai; Eggimann, P; Senn, L (2016). New genotyping method discovers sustained nosocomial Pseudomonas aeruginosa outbreak in an intensive care burn unit. Journal of hospital infection, 94(1), pp. 2-7. Elsevier 10.1016/j.jhin.2016.05.011

Martin-Loeches, Ignacio; Wunderink, Richard G; Nanchal, Rahul; Lefrant, Jean Yves; Kapadia, Farhad; Sakr, Yasser; Vincent, Jean-Louis; Jakob, Stephan (2016). Determinants of time to death in hospital in critically ill patients around the world. Intensive care medicine, 42(9), pp. 1454-1460. Springer 10.1007/s00134-016-4479-0

Cioccari, Luca; Luethi, Nora; Weber, Ulrike; Hilton, Andrew; Takala, Jukka; Bellomo, Rinaldo (2016). The native cardiac output in human sepsis: a systematic review. Critical care and resuscitation, 18(3), pp. 148-156. College of Intensive Care Medicine of Australia and New Zealand

Myhre, Peder L; Ottesen, Anett H; Okkonen, Marjatta; Linko, Rita; Stridsberg, Mats; Nygård, Ståle; Christensen, Geir; Pettilä, Ville Yrjö Olavi; Omland, Torbjørn; Røsjø, Helge (2016). Prognostic Value of Secretoneurin in Patients with Acute Respiratory Failure: Data from the FINNALI Study. Clinical chemistry, 62(10), pp. 1380-1389. American Association for Clinical Chemistry 10.1373/clinchem.2016.258764

Eggmann, Sabrina; Verra, Martin L; Luder, Gere; Takala, Jukka; Jakob, Stephan (2016). Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: a study protocol for a randomised controlled trial. Trials, 17, p. 403. BioMed Central 10.1186/s13063-016-1533-8

Ristagno, Giuseppe; Masson, Serge; Tiainen, Marjaana; Bendel, Stepani; Bernasconi, Roberto; Varpula, Tero; Milani, Valentina; Vaahersalo, Jukka; Magnoli, Michela; Spanuth, Eberhard; Barlera, Simona; Latini, Roberto; Hoppu, Sanna; Pettilä, Ville Yrjö Olavi; Skrifvars, Markus B (2016). Elevated plasma heparin-binding protein is associated with early death after resuscitation from cardiac arrest. Critical care, 20(251), p. 251. BioMed Central 10.1186/s13054-016-1412-4

Djafarzadeh, Siamak; Vuda, Madhusudanarao; Jeger, Victor; Takala, Jukka; Jakob, Stephan (2016). The Effects of Fentanyl on Hepatic Mitochondrial Function. Anesthesia and analgesia, 123(2), pp. 311-325. International Anesthesia Research Society 10.1213/ANE.0000000000001280

Pettilä, Ville Yrjö Olavi; Hjortrup, Peter Buhl; Jakob, Stephan; Wilkman, Erika; Perner, Anders; Takala, Jukka (2016). Control groups in recent septic shock trials: a systematic review. Intensive care medicine, 42(12), pp. 1912-1921. Springer 10.1007/s00134-016-4444-y

Berger, David; Werner Möller, Per; Weber, Alberto; Bloch, Andreas; Bloechlinger, Stefan; Hänggi, Matthias; Sondergaard, Soren; Jakob, Stephan; Magder, Sheldon; Takala, Jukka (2016). Effect of PEEP, blood volume, and inspiratory hold maneuvers on venous return. American journal of physiology - heart and circulatory physiology, 311(3), H794-H806. American Physiological Society 10.1152/ajpheart.00931.2015

Löffel, Lukas; Burkhard, Fiona C.; Takala, Jukka; Wüthrich, Patrick Yves (2016). Impact of a Potassium-enriched, Chloride-depleted 5% Glucose Solution on Gastrointestinal Function after Major Abdominopelvic Surgery: Results of a Randomized Controlled Trial. Anesthesiology, 125(4), p. 1. Lippincott Williams & Wilkins 10.1097/ALN.0000000000001238

Chrysou, Konstantina; Gioutsos, Konstantinos; Filips, Alexandra; Schmid, Roger; Schmid, Ralph; Kocher, Gregor (2016). Spontaneous right whole-lung torsion secondary to bronchial carcinoma: a case report. Journal of cardiothoracic surgery, 11(107), p. 107. Biomed Central 10.1186/s13019-016-0506-z

Røsjø, Helge; Stridsberg, Mats; Ottesen, Anett H; Nygård, Ståle; Christensen, Geir; Pettilä, Ville Yrjö Olavi; Linko, Rita; Karlsson, Sari; Varpula, Tero; Ruokonen, Esko; Omland, Torbjørn (2016). Prognostic Value of Secretoneurin in Critically Ill Patients With Infections. Critical care medicine, 44(10), p. 1. Lippincott Williams & Wilkins 10.1097/CCM.0000000000001832

Bakker, Jan; Takala, Jukka (2016). Vasopressor therapy: not like antibiotics! Intensive care medicine, 42(7), pp. 1195-1196. Springer 10.1007/s00134-016-4335-2

Myhre, Peder L; Tiainen, Marjaana; Pettilä, Ville Yrjö Olavi; Vaahersalo, Jukka; Hagve, Tor-Arne; Kurola, Jouni; Varpula, Tero; Omland, Torbjørn; Røsjø, Helge (2016). NT-proBNP in patients with out-of-hospital cardiac arrest: Results from the FINNRESUSCI Study. Resuscitation, 104, pp. 12-18. Elsevier Science Ireland 10.1016/j.resuscitation.2016.04.007

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Laurikkala, Johanna; Wilkman, Erika; Pettilä, Ville Yrjö Olavi; Kurola, Jouni; Reinikainen, Matti; Hoppu, Sanna; Ala-Kokko, Tero; Tallgren, Minna; Tiainen, Marjaana; Vaahersalo, Jukka; Varpula, Tero; Skrifvars, Markus B (2016). Mean arterial pressure and vasopressor load after out-of-hospital cardiac arrest: Associations with one-year neurologic outcome. Resuscitation, 105, pp. 116-122. Elsevier Science Ireland 10.1016/j.resuscitation.2016.05.026

Henzen, Dominik; Zanella do Amaral Campos, Pedro Paulo; Schmidhalter, Daniel; Volken, Werner; Mackeprang, Paul-Henry; Malthaner, Marco; Fix, Michael; Manser, Peter (June 2016). TH-AB-201-05: Determining the Direction Distribution of the Primary Radiation for a Cyberknife-M6. Medical physics, 43(6), p. 3850. American Association of Physicists in Medicine AAPM 10.1118/1.4958033

Vincent, Jean-Louis; Takala, Jukka; Moreno, Rui P; Sakr, Yasser; Marshall, John C (2016). The Richmond Agitation-Sedation Scale Should Not Be Used to Evaluate Neurologic Function. Critical care medicine, 44(6), e450. Lippincott Williams & Wilkins 10.1097/CCM.0000000000001597

Vincent, Jean-Louis; Shehabi, Yahya; Walsh, Timothy S; Pandharipande, Pratik P; Ball, Jonathan A; Spronk, Peter; Longrois, Dan; Strøm, Thomas; Conti, Giorgio; Funk, Georg-Christian; Badenes, Rafael; Mantz, Jean; Spies, Claudia; Takala, Jukka (2016). Comfort and patient-centred care without excessive sedation: the eCASH concept. Intensive care medicine, 42(6), pp. 962-971. Springer 10.1007/s00134-016-4297-4

Gisler, Valentin; Müller, Sabine; Müller, Lionel; Jörg-Walther, Lukas; Sendi, Parham (2016). Acute Angioedema Triggered by Daptomycin. Infectious diseases and therapy, 5(2), pp. 201-205. Springer 10.1007/s40121-016-0111-4

Zuurbier, Susanna M; Arnold, Marcel; Middeldorp, Saskia; Broeg-Morvay, Anne; Silvis, Suzanne M; Heldner, Mirjam Rachel; Meisterernst, Julia Anne; Nemeth, Banne; Meulendijks, Eva R; Stam, Jan; Cannegieter, Suzanne C; Coutinho, Jonathan M (2016). Risk of Cerebral Venous Thrombosis in Obese Women. JAMA neurology, 73(5), pp. 579-584. American Medical Association 10.1001/jamaneurol.2016.0001

Gonzalez, Manuel R; Fleuchot, Betty; Lauciello, Leonardo; Jafari, Paris; Applegate, Lee Ann; Raffoul, Wassim; Que, Yok-Ai; Perron, Karl (2016). Effect of Human Burn Wound Exudate on Pseudomonas aeruginosa Virulence. mSphere, 1(2) American Society for Microbiology 10.1128/mSphere.00111-15

Takala, Jukka; Jakob, Stephan (2016). Oxygen transport in the critically ill. In: Webb, Andrew; Angus, Derek; Finfer, Simon; Gattinoni, Luciano; Singer, Mervyn (eds.) Oxford Textbook of Critical Care (pp. 636-639). Oxford University Press

Reintam Blaser, Annika; Jakob, Stephan; Starkopf, Joel (2016). Gastrointestinal failure in the ICU. Current opinion in critical care, 22(2), pp. 128-141. Lippincott Williams & Wilkins 10.1097/MCC.0000000000000286

Takala, Jukka (2016). Resource management and budgeting in critical care. In: Webb, Andrew; Angus, Derek; Finfer, Simon; Gattinoni, Luciano; Singer, Mervyn (eds.) Oxford Textbook of Critical Care (pp. 90-93). Oxford University Press 10.1093/med/9780199600830.003.0021

Zante, Björn; Dietler, Roland; Takala, Jukka (2016). Internal reporting system: we must look behind the curtain. Intensive care medicine, 42(6), p. 1100. Springer 10.1007/s00134-016-4289-4

Berger, David; Blöchlinger, Stefan; von Haehling, Stephan; Doehner, Wolfram; Takala, Jukka; Z'Graggen, Werner Josef; Schefold, Joerg C. (2016). Dysfunction of respiratory muscles in critically ill patients on the intensive care unit. Journal of cachexia, sarcopenia and muscle, 7(4), pp. 403-412. Wiley 10.1002/jcsm.12108

Heringlake, M; Bein, B; Buerke, M; Damjanovic, D; Ebelt, H; Groesdonk, H V; Markewitz, A; Möckel, M; Moosdorf, R; Pilarczyk, K; Reuter, D A; Sander, M; Schmitt, A; Trummer, G; Treskatsch, S; Von der Brelie, M; Zante, Björn; Zarbock, A; Haake, N (2016). Escalation of therapy without evidence: a "may" does not imply a "should"! Intensive care medicine, 42(3), pp. 485-487. Springer 10.1007/s00134-015-4145-y

Siren, Juuso; Vaahersalo, Jukka; Skrifvars, Markus; Pettilä, Ville Yrjö Olavi; Tiainen, Marjaana; Tikkanen, Ilkka; Lakkisto, Päivi (2016). Plasma Heme Oxygenase-1 in Patients Resuscitated from out-of-Hospital Cardiac Arrest. Shock, 45(3), pp. 320-325. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000521

Scherbakov, Nadja; Knops, Michael; Ebner, Nicole; Valentova, Miroslava; Sandek, Anja; Grittner, Ulrike; Dahinden, Pius; Hettwer, Stefan; Schefold, Joerg C.; von Haehling, Stephan; Anker, Stefan D; Joebges, Michael; Doehner, Wolfram (2016). Evaluation of C-terminal Agrin Fragment as a marker of muscle wasting in patients after acute stroke during early rehabilitation. Journal of cachexia, sarcopenia and muscle, 7(1), pp. 60-67. Wiley 10.1002/jcsm.12068

Wiegand, Jan; Hickson, Liz; Merz, Tobias Michael (2016). Indicators of external ventricular drainage-related infections--a retrospective observational study. Acta neurochirurgica, 158(3), pp. 595-601. Springer 10.1007/s00701-016-2709-4

Basciani, Reto Marco; Rindlisbacher, Antje; Begert, Esther; Brander, Luc; Jakob, Stephan; Etter, Reto; Carrel, Thierry; Eberle, Balthasar (2016). Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial. European journal of anaesthesiology, 33(6), pp. 417-424. Lippincott Williams & Wilkins 10.1097/EJA.0000000000000434

Takala, Jukka (2016). Volume responsive, but does the patient need volume? Intensive care medicine, 42(9), pp. 1461-1463. Springer 10.1007/s00134-015-4172-8

Pagnamenta, Alberto; Bruno, Roberta; Gemperli, Armin; Chiesa, Alessandro; Previsdomini, Marco; Corti, Fabio; Merlani, Paolo; Cottini, Silvia; Llamas, Michael; Rothen, Hans Ulrich (2016). Impact of a communication strategy on family satisfaction in the intensive care unit. Acta anaesthesiologica Scandinavica, 60(6), pp. 800-809. Wiley-Blackwell 10.1111/aas.12692

Pichler Hefti, Jacqueline Renée; Leichtle, Alexander Benedikt; Stutz, Monika; Hefti, Urs; Geiser, Thomas; Huber, Andreas R; Merz, Tobias Michael (2016). Increased endothelial microparticles and oxidative stress at extreme altitude. European journal of applied physiology, 116(4), pp. 739-748. Springer 10.1007/s00421-015-3309-3

Vaara, Suvi T; Parviainen, Ilkka; Pettilä, Ville Yrjö Olavi; Nisula, Sara; Inkinen, Outi; Uusaro, Ari (2016). Association of oliguria with the development of acute kidney injury in the critically ill. Kidney international, 89(1), pp. 200-208. Elsevier 10.1016/j.kint.2015.12.007

Horvath, Thomas; Fischer, Urs; Müller, Lionel; Ott, Sebastian Robert; Bassetti, Claudio; Wiest, Roland; Sendi, Parham; Schefold, Joerg C. (2016). Mycoplasma-induced minimally conscious state. SpringerPlus, 5, p. 143. Springer 10.1186/s40064-016-1832-2

Rothen, Hans Ulrich; Hänggi, Matthias (2016). Chapter 2: Daily goal discussions. In: Guidet, Bertrand; Valentin, Andreas; Flaatten, Hans (eds.) Quality Management in Intensive Care - A Practical Guide (pp. 9-14). Cambridge: Cambridge University Press

Bechtel-Grosch, Ursina; Béguelin, Charles Antoine; Berezowska, Sabina Anna; Dufour, Jean-François; Takala, Jukka; Schefold, Joerg C. (2016). Fulminant hepatic and multiple organ failure following acute viral tonsillitis: a case report. Journal of medical case reports, 10(7), p. 7. BioMed Central 10.1186/s13256-015-0777-3

Zürcher, Patrick; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Grossholz, Marius; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2016). A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model. BMC neurology, 16, p. 43. BioMed Central 10.1186/s12883-016-0565-8

Berger, David; Takala, Jukka (2016). Hypotension and hypovolemia during hemodialysis: is the usual suspect innocent? Critical care, 20(1), p. 140. BioMed Central 10.1186/s13054-016-1307-4

Vaara, Suvi T; Lakkisto, Päivi; Immonen, Katariina; Tikkanen, Ilkka; Ala-Kokko, Tero; Pettilä, Ville Yrjö Olavi (2016). Urinary Biomarkers Indicative of Apoptosis and Acute Kidney Injury in the Critically Ill. PLoS ONE, 11(2), e0149956. Public Library of Science 10.1371/journal.pone.0149956

Kirkegaard, Hans; Rasmussen, Bodil S; de Haas, Inge; Nielsen, Jørgen Feldbæk; Ilkjær, Susanne; Kaltoft, Anne; Jeppesen, Anni Nørregaard; Grejs, Anders; Duez, Christophe Henri Valdemar; Larsen, Alf Inge; Pettilä, Ville Yrjö Olavi; Toome, Valdo; Arus, Urmet; Taccone, Fabio Silvio; Storm, Christian; Skrifvars, Markus B; Søreide, Eldar (2016). Time-differentiated target temperature management after out-of-hospital cardiac arrest: a multicentre, randomised, parallel-group, assessor-blinded clinical trial (the TTH48 trial): study protocol for a randomised controlled trial. Trials, 17(1), p. 228. BioMed Central 10.1186/s13063-016-1338-9

Pettilä, Ville Yrjö Olavi; Merz, Tobias Michael; Wilkman, Erika; Perner, Anders; Karlsson, Sari; Lange, Theis; Hästbacka, Johanna; Hjortrup, Peter Buhl; Kuitunen, Anne; Jakob, Stephan; Takala, Jukka (2016). Targeted tissue perfusion versus macrocirculation-guided standard care in patients with septic shock (TARTARE-2S): study protocol and statistical analysis plan for a randomized controlled trial. Trials, 17(384), p. 384. BioMed Central 10.1186/s13063-016-1515-x

Berger, David; Werner Möller, Per; Takala, Jukka (2016). Reply to “Letter to the editor: Why persist in the fallacy that mean systemic pressure drives venous return?”. American journal of physiology - heart and circulatory physiology, 311(5), H1336-H1337. American Physiological Society 10.1152/ajpheart.00622.2016

Vaara, Suvi T; Hollmén, Maija; Korhonen, Anna-Maija; Maksimow, Mikael; Ala-Kokko, Tero; Salmi, Marko; Jalkanen, Sirpa; Pettilä, Ville Yrjö Olavi (2016). Soluble CD73 in Critically Ill Septic Patients - Data from the Prospective FINNAKI Study. PLoS ONE, 11(10), e0164420. Public Library of Science 10.1371/journal.pone.0164420

Krag, Mette; Perner, Anders; Wetterslev, Jørn; Wise, Matt P.; Borthwick, Mark; Bendel, Stepani; Pelosi, Paolo; Keus, Frederik; Guttormsen, Anne Berit; Schefold, Joerg C.; Møller, Morten Hylander (2016). Stress ulcer prophylaxis with a proton pump inhibitor versus placebo in critically ill patients (SUP-ICU trial): study protocol for a randomised controlled trial. Trials, 17(205), p. 205. BioMed Central 10.1186/s13063-016-1331-3

Stalder, Grégoire; Que, Yok-Ai; Calzavarini, Sara; Burnier, Laurent; Kosinski, Christophe; Ballabeni, Pierluigi; Roger, Thierry; Calandra, Thierry; Duchosal, Michel A; Liaudet, Lucas; Eggimann, Philippe; Angelillo-Scherrer, Anne (2016). Study of Early Elevated Gas6 Plasma Level as a Predictor of Mortality in a Prospective Cohort of Patients with Sepsis. PLoS ONE, 11(10), e0163542. Public Library of Science 10.1371/journal.pone.0163542

Tsurumi, Amy; Que, Yok-Ai; Ryan, Colleen M; Tompkins, Ronald G; Rahme, Laurence G (2016). TNF-α/IL-10 Ratio Correlates with Burn Severity and May Serve as a Risk Predictor of Increased Susceptibility to Infections. Frontiers in Public Health, 4(216), p. 216. Frontiers Media 10.3389/fpubh.2016.00216

Hazan, Ronen; Que, Yok-Ai; Maura, Damien; Strobel, Benjamin; Majcherczyk, Paul Anthony; Hopper, Laura Rose; Wilbur, David J.; Hreha, Teri N.; Barquera, Blanca; Rahme, Laurence G. (2016). Auto Poisoning of the Respiratory Chain by a Quorum-Sensing-Regulated Molecule Favors Biofilm Formation and Antibiotic Tolerance. Current Biology, 26(2), pp. 195-206. Cell Press 10.1016/j.cub.2015.11.056

Fournier, Anne; Voirol, Pierre; Krähenbühl, Marie; Bonnemain, Claire-Lise; Fournier, Camille; Pantet, Olivier; Pagani, Jean-Luc; Revelly, Jean-Pierre; Dupuis-Lozeron, Elise; Sadeghipour, Farshid; Pannatier, André; Eggimann, Philippe; Que, Yok-Ai (2016). Antibiotic consumption to detect epidemics of Pseudomonas aeruginosa in a burn centre: A paradigm shift in the epidemiological surveillance of Pseudomonas aeruginosa nosocomial infections. Burns, 42(3), pp. 564-570. Elsevier 10.1016/j.burns.2015.10.030

Zürcher, Patrick; Groen, Justus L.; Aries, Marcel J.H.; Steyerberg, Ewout W.; Maas, Andrew I.R.; Ercole, Ari; Menon, David K. (2016). Reliability and Validity of the Therapy Intensity Level Scale: Analysis of Clinimetric Properties of a Novel Approach to Assess Management of Intracranial Pressure in Traumatic Brain Injury. Journal of neurotrauma, 33(19), pp. 1768-1774. M.A. Liebert 10.1089/neu.2015.4266

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Steinbeck, Lisa; Ebner, Nicole; Valentova, Miroslava; Bekfani, Tarek; Elsner, Sebastian; Dahinden, Pius; Hettwer, Stefan; Scherbakov, Nadja; Sandek, Anja; Springer, Jochen; Doehner, Wolfram; Anker, Stefan D; von Haehling, Stephan; Schefold, Joerg C. (2015). Detection of muscle wasting in patients with chronic heart failure using C-terminal agrin fragment: results from the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF). European journal of heart failure, 17(12), pp. 1283-1293. Oxford University Press 10.1002/ejhf.400

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Zubler, Frederic; Koenig, Christa; Steimer, Andreas; Jakob, Stephan; Schindler, Kaspar Anton; Gast, Heidemarie (2015). Prognostic and diagnostic value of EEG signal coupling measures in coma. Clinical neurophysiology, 127(8), pp. 2942-2952. Elsevier 10.1016/j.clinph.2015.08.022

Cioccari, Luca; Gautschi, Matthias; Etter, Reto; Weck, Anja; Takala, Jukka (2015). Further Concerns About Glutamine: A Case Report on Hyperammonemic Encephalopathy. Critical care medicine, 43(10), e458-e460. Lippincott Williams & Wilkins 10.1097/CCM.0000000000001151

Fung, Christian; Inglin, Fabienne; Murek, Michael Konrad; Balmer, Mathias; Abu-Isa, Janine; Z'Graggen, Werner Josef; Ozdoba, Christoph; Gralla, Jan; Jakob, Stephan; Takala, Jukka; Beck, Jürgen; Raabe, Andreas (2015). Reconsidering the logic of World Federation of Neurosurgical Societies grading in patients with severe subarachnoid hemorrhage. Journal of neurosurgery, 124(2), pp. 299-304. American Association of Neurological Surgeons 10.3171/2015.2.JNS14614

Ebert, Thomas; Pichler Hefti, Jacqueline Renée; Merz, Tobias Michael; Hoffmann, Annett; Stumvoll, Michael; Fasshauer, Mathias; Kralisch, Susan (15 September 2015). The adipokine adipocyte fatty acid-binding protein in high altitude (Unpublished). In: Europäische Diabetestagung. Stockholm. 15.09.2015.

Ebert, Thomas; Pichler Hefti, Jacqueline Renée; Merz, Tobias Michael; Hoffmann, Annett; Stumvoll, Michael; Fasshauer, Mathias; Kralisch, Susan (15 September 2015). The adipokine adipocyte fatty acid-binding protein in high altitude (Unpublished). In: Europäische Diabetestagung. Stockholm. 15.09.2015.

Frick, Tamara; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Hänggi, Matthias (2015). An improved simple rat model for global cerebral ischaemia by induced cardiac arrest. Neurological research, 38(4), pp. 373-380. Maney 10.1179/1743132815Y.0000000090

Merz, Tobias Michael; Pichler Hefti, Jacqueline Renée; Hefti, Urs; Huber, Andreas; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2015). Changes in mitochondrial enzymatic activities of monocytes during prolonged hypobaric hypoxia and influence of antioxidants: A randomized controlled study. Redox report, 20(5), pp. 234-240. Maney Publishing 10.1179/1351000215Y.0000000007

O'Sullivan, Crochan John; Wenaweser, Peter Martin; Ceylan, Osman Ernst; Stortecky, Stefan; Spitzer, Ernest; Zanchin, Thomas; Praz, Fabien; Pilgrim, Thomas; Khattab, Ahmed Aziz; Meier, Bernhard; Windecker, Stephan; Büllesfeld, Lutz; Tüller, David; Rat-Wirtzler, Julie; Heg, Dik; Huber, Christoph; Carrel, Thierry; Nietlispach, Fabian (2015). Response To Letter Regarding Article, "Effect of Pulmonary Hypertension Hemodynamic Presentation on Clinical Outcomes in Patients With Severe Symptomatic Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation: Insights From the New Proposed Pulmonary Hypertension Classification". Circulation: Cardiovascular interventions, 8(9), e003064. Lippincott Williams & Wilkins 10.1161/CIRCINTERVENTIONS.115.003064

Bloechlinger, Stefan; Berger, David; Bryner, Jürg; Roost, Eva; Jakob, Stephan; Dünser, Martin W; Takala, Jukka (2015). Changes in Left Ventricular Torsion Early Postoperatively After Aortic Valve Replacement and at Long-Term Follow-up. Journal of cardiothoracic and vascular anesthesia, 29(4), pp. 860-867. Elsevier 10.1053/j.jvca.2015.01.010

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Bänziger, B; Regueira, T; Vogt, R; Brandt, S; Vandevelde, M; Jakob, Stephan (2015). Neurohistological abnormalities during early porcine endotoxemia. Acta anaesthesiologica Scandinavica, 59(5), pp. 586-597. Wiley-Blackwell 10.1111/aas.12512

Coslovsky, Michael; Takala, Jukka; Exadaktylos, Aristomenis; Martinolli, Luca; Merz, Tobias M (2015). A clinical prediction model to identify patients at high risk of death in the emergency department. Intensive care medicine, 41(6), pp. 1029-1036. Springer 10.1007/s00134-015-3737-x

Pitzschke, Andreas; Lovisa, Blaise; Seydoux, Olivier; Hänggi, Matthias; Oertel, Markus Florian; Zellweger, Matthieu; Tardy, Yanik; Wagnières, Georges (2015). Optical properties of rabbit brain in the red and near-infrared: changes observed under in vivo, postmortem, frozen, and formalin-fixated conditions. Journal of biomedical optics, 20(2), p. 25006. SPIE International Society for Optical Engineering 10.1117/1.JBO.20.2.025006

Bendel, Stepani; Springe, Dirk; Pereira, Adriano José; Grandgirard, Denis; Leib, Stephen; Putzu, Alessandro; Schlickeiser, Jannis; Jakob, Stephan M.; Takala, Jukka; Hänggi, Matthias (2015). Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? BMC anesthesiology, 15(2), p. 2. BioMed Central 10.1186/1471-2253-15-2

Wagner, Franca; Hänggi, Matthias; Wagner, Bendicht Peter; Weck, Anja; Weisstanner, Christian; Grunt, Sebastian; Z'Graggen, Werner Josef; Gralla, Jan; Wiest, Roland; Verma, Rajeev Kumar (2015). The value of susceptibility-weighted imaging (SWI) in patients with non-neonatal hypoxic-ischemic encephalopathy. Resuscitation, 88, pp. 75-80. Elsevier Science Ireland 10.1016/j.resuscitation.2014.12.024

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Fung, Christian; Balmer, Mathias; Murek, Michael; Z'Graggen, Werner Josef; Abu-Isa, Janine; Ozdoba, Christoph; Hänggi, Matthias; Jakob, Stephan; Raabe, Andreas; Beck, Jürgen (2015). Impact of early-onset seizures on grading and outcome in patients with subarachnoid hemorrhage. Journal of neurosurgery, 122(2), pp. 408-413. American Association of Neurological Surgeons 10.3171/2014.10.JNS14163

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Kottke, Raimund; Pichler Hefti, Jacqueline Renée; Rummel, Christian; Hauf, Martinus; Hefti, Urs; Merz, Tobias Michael (2015). Morphological Brain Changes after Climbing to Extreme Altitudes-A Prospective Cohort Study. PLoS ONE, 10(10), e0141097. Public Library of Science 10.1371/journal.pone.0141097

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Corrêa, Thiago Domingos; Jakob, Stephan; Takala, Jukka (2015). Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? Critical care, 19(264), p. 264. BioMed Central 10.1186/s13054-015-0958-x

Turunen, Heidi; Jakob, Stephan; Ruokonen, Esko; Kaukonen, Kirsi-Maija; Sarapohja, Toni; Apajasalo, Marjo; Takala, Jukka (2015). Dexmedetomidine versus standard care sedation with propofol or midazolam in intensive care: an economic evaluation. Critical care, 19(67), p. 67. BioMed Central 10.1186/s13054-015-0787-y

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Jeger, Victor; Brandt, Sebastian; Porta, Francesca; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2015). Dose response of endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed research international, 2015, p. 353074. Hindawi Publishing Corporation 10.1155/2015/353074

Pfortmüller, Carmen; Pauchard-Neuwerth, Sandra Elisabeth; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis; Lindner, Gregor (2015). Primary Hyperventilation in the Emergency Department: A First Overview. PLoS ONE, 10(6), e0129562. Public Library of Science 10.1371/journal.pone.0129562

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Marbacher, Serge; Neuschmelting, Volker; Andereggen, Lukas; Widmer, Hans Rudolf; von Gunten, Michael; Takala, Jukka; Jakob, Stephan; Fandino, Javier (2014). Early brain injury linearly correlates with reduction in cerebral perfusion pressure during the hyperacute phase of subarachnoid hemorrhage. Intensive care medicine experimental, 2(1), p. 30. Springer 10.1186/s40635-014-0030-1

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Hänggi, Matthias; Jakob, Stephan; Takala, Jukka (2014). Sedation level and prevalence of delirium: response to Brummel and Ely. Intensive care medicine, 40(1), p. 136. Springer 10.1007/s00134-013-3092-8

Berger, David; Blöchlinger, Stefan; Takala, Jukka; Sinderby, Christer; Brander, Lukas (2014). Heart-lung interactions during neurally adjusted ventilatory assist. Critical care, 18(5), p. 499. BioMed Central 10.1186/s13054-014-0499-8

Pereira, A. J.; Jeger, V.; Fahrner, R.; Djafarzadeh, Siamak; Lensch, Michael; Takala, Jukka; Jakob, Stephan (2014). Interference of angiotensin II and enalapril with hepatic blood flow regulation. American journal of physiology - gastrointestinal and liver physiology, 307(6), G655-G663. American Physiological Society 10.1152/ajpgi.00150.2014

Corrêa, Thiago D.; Jeger, Victor; Pereira, Adriano José; Takala, Jukka; Djafarzadeh, Siamak; Jakob, Stephan (2014). Angiotensin II in Septic Shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis. Critical care medicine, 42(8), e550-e559. Lippincott Williams & Wilkins 10.1097/CCM.0000000000000397

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Takala, Jukka (2014). Reply: Is the Glass of Delirium Half Full or Half Empty? American journal of respiratory and critical care medicine, 189(11), p. 1444. American Lung Association 10.1164/rccm.201404-0642LE

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Perren, A; Cerutti, B; Merlani, P; Perren, I; Previsdomini, M; Massarotto, P; Kaufmann, M; Rothen, Hans Ulrich (2014). SwissScoring--a nationwide survey of NEMS assessing practices and its accuracy. Acta anaesthesiologica Scandinavica, 58(4), pp. 478-486. Wiley-Blackwell 10.1111/aas.12283

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Ackermann, Karin; Bostock, Hugh; Brander, Lukas; Schröder, Ralph; Djafarzadeh, Siamak; Tuchscherer, Daniel; Jakob, Stephan; Takala, Jukka; Z'Graggen, Werner Josef (2014). Early changes of muscle membrane properties in porcine faecal peritonitis. Critical care, 18(4), p. 484. BioMed Central 10.1186/s13054-014-0484-2

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Takala, Jukka (2014). Of Delirium and Sedation. American journal of respiratory and critical care medicine, 189(6), pp. 622-624. American Lung Association 10.1164/rccm.201401-0195ED

Jakob, Stephan; Ruokonen, E.; Takala, Jukka (2014). Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients. British journal of anaesthesia, 112(3), pp. 581-582. Oxford University Press 10.1093/bja/aeu032

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Kretzschmar, Moritz; Schilling, Thomas; Vogt, Andreas; Rothen, Hans Ulrich; Borges, João Batista; Hachenberg, Thomas; Larsson, Anders; Baumgardner, James E; Hedenstierna, Göran (2013). Multiple inert gas elimination technique by micropore membrane inlet mass spectrometry--a comparison with reference gas chromatography. Journal of applied physiology, 115(8), pp. 1107-1118. American Physiological Society 10.1152/japplphysiol.00072.2013

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Gorrasi, José; Eleftheriadis, Anestis; Takala, Jukka; Brandt, Sebastian; Djafarzadeh, Siamak; Brügger, Lukas; Bracht, Hendrik; Jakob, Stephan (2013). Different Contribution of Splanchnic Organs to Hyperlactatemia in Fecal Peritonitis and Cardiac Tamponade. BioMed research international, 2013, pp. 1-8. Hindawi Publishing Corporation 10.1155/2013/251084

Pichler Hefti, Jacqueline Renée; Sonntag, Denise; Hefti, Urs; Risch, Lorenz; Schoch, Otto D.; Turk, Alexander J.; Hess, Thomas; Bloch, Konrad E.; Maggiorini, Marco; Merz, Tobias Michael; Weinberger, Klaus M.; Huber, Andreas R. (2013). Oxidative Stress in Hypobaric Hypoxia and Influence on Vessel-Tone Modifying Mediators. High altitude medicine & biology, 14(3), pp. 273-279. Mary Ann Liebert 10.1089/ham.2012.1110

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Corrêa, Thiago Domingos; Takala, Jukka; Jakob, Stephan (2013). Target blood pressure in sepsis: between a rock and a hard place. Critical care, 17(3), p. 433. BioMed Central 10.1186/cc12692

Jeger, Victor; Djafarzadeh, Siamak; Jakob, Stephan; Takala, Jukka (2013). Mitochondrial function in sepsis. European journal of clinical investigation, 43(5), pp. 532-542. Wiley-Blackwell 10.1111/eci.12069

Cioccari, Luca; Baur, Hans-Rudolf; Berger, David; Wiegand, Jan; Takala, Jukka; Merz, Tobias Michael (2013). Hemodynamic assessment of critically ill patients using a miniaturized transesophageal echocardiography probe. Critical care, 17(3), R121. BioMed Central 10.1186/cc12793

Corrêa, Thiago Domingos; Vuda, Madhusudanarao; Takala, Jukka; Djafarzadeh, Siamak; Silva, Eliézer; Jakob, Stephan (2013). Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function. Critical care, 17(1), R21. BioMed Central 10.1186/cc12495

Lehmann, Laura; Bendel, Stepani; Uehlinger, Dominik E; Takala, Jukka; Schafer, Margaret; Reinert, Michael; Jakob, Stephan M (2013). Randomized, Double-Blind Trial of the Effect of Fluid Composition on Electrolyte, Acid-Base, and Fluid Homeostasis in Patients Early After Subarachnoid Hemorrhage. Neurocritical care, 18(1), pp. 5-12. New York, N.Y.: Humana Press Inc 10.1007/s12028-012-9764-3

Torgersen, Christian-Erik; Meichtry, Jurka; Schmittinger, Christian A; Blöchlinger, Stefan; Jakob, Stephan M; Takala, Jukka; Dünser, Martin Wolfgang (2013). Haemodynamic variables and functional outcome in hypothermic patients following out-of-hospital cardiac arrest. Resuscitation, 84(6), pp. 798-804. Shannon: Elsevier Science Ireland 10.1016/j.resuscitation.2012.10.012

Andereggen, Lukas; Beck, Jürgen; Z'Graggen, Werner; Andres, Robert; Murek, Michael; Hänggi, Matthias; Schroth, Gerhard; Reinert, Michael; Raabe, Andreas; Gralla, Jan (2013). Multiple endovascular interventions in patients suffering from refractory cerebral vasospasm. Swiss Archives of Neurology and Psychiatry, 164(4).

Hänggi, Matthias; Blum, Sina; Brechbuehl, Ruth; Brunello, Anna; Jakob, Stephan; Takala, Jukka (2013). Effect of sedation level on the prevalence of delirium when assessed with CAM-ICU and ICDSC. Intensive care medicine, 39(12), pp. 2171-2179. Springer Berlin Heidelberg 10.1007/s00134-013-3034-5

Merz, Tobias Michael; Bosch, Martina M.; Barthelmes, Daniel; Pichler Hefti, Jacqueline Renée; Hefti, Urs; Schmitt, Kai-Uwe; Bloch, Konrad E.; Schoch, Otto D.; Hess, Thomas; Turk, Alexander J.; Schwarz, Urs (2013). Cognitive performance in high-altitude climbers: a comparative study of saccadic eye movements and neuropsychological tests. European journal of applied physiology, 113(8), pp. 2025-2037. Springer Berlin Heidelberg 10.1007/s00421-013-2635-6

Warncke, Cornelius; Chuard, C.; Tassaux, D.; Vajtai, I.; Hänggi, Matthias (2013). Headache and transient aphasia in a 35-year-old female patient. Internist, 54(5), pp. 624-629. Springer-Verlag 10.1007/s00108-013-3253-4


Pereira, J M; Moreno, R P; Matos, R; Rhodes, A; Martin-Loeches, I; Cecconi, M; Lisboa, T; Rello, J; Rothen, Hans Ulrich (2012). Severity assessment tools in ICU patients with 2009 influenza A (H1N1) pneumonia. Clinical microbiology and infection, 18(10), pp. 1040-1048. Blackwell Publishing 10.1111/j.1469-0691.2011.03736.x

Dahlqvist, M; Venzin, R; König, S; Faber, K; Weinmann, W; Terbeck, S; Ceschi, A; Dünser, M W (2012). Haemodialysis in Taxus Baccata poisoning: a case report. QJM - an international journal of medicine, 105(4), pp. 359-61. Oxford: Oxford University Press 10.1093/qjmed/hcr037

Vuda, Madhusudanarao; Brander, Lukas; Schröeder, Ralph; Jakob, Stephan M; Takala, Jukka; Djafarzadeh, Siamak (2012). Effects of catecholamines on hepatic and skeletal muscle mitochondrial respiration after prolonged exposure to faecal peritonitis in pigs. Innate immunity, 18(2), pp. 217-30. Los Angeles, Calif.: Sage Publications 10.1177/1753425911398279

Haenggi, Matthias; Andermatt, Anna; Anthamatten, Claudia; Galimanis, Aikaterini; Mono, Marie-Louise; Alfieri, Alexander; Fung, Christian; Takala, Jukka (2012). Co2-dependent vasomotor reactivity of cerebral arteries in patients with severe traumatic brain injury: time course and effect of augmentation of cardiac output with dobutamine. Journal of neurotrauma, 29(9), pp. 1779-84. New York, N.Y.: M.A. Liebert 10.1089/neu.2011.1809

Fung, Christian; Z'graggen, Werner J; Beck, Jürgen; Gralla, Jan; Jakob, Stephan M; Schucht, Philippe; Raabe, Andreas (2012). Traumatic subarachnoid hemorrhage, basal ganglia hematoma and ischemic stroke caused by a torn lenticulostriate artery. Acta neurochirurgica, 154(1), pp. 59-62. Wien: Springer Vienna 10.1007/s00701-011-1162-7

Jakob, Stephan M; Bracht, Hendrik; Porta, Francesca; Balsiger, Bruno M; Brander, Lukas; Knuesel, Rafael; Feng, Hong-Qiang; Kolarova, Anna; Ma, Yingmin; Takala, Jukka (2012). Effects of cardiac preload reduction and dobutamine on hepatosplanchnic blood flow regulation in porcine endotoxemia. American journal of physiology - gastrointestinal and liver physiology, 303(2), G247-55. Bethesda, Md.: American Physiological Society 10.1152/ajpgi.00433.2011

Chiusa, Manuel; Hool, Sara-Lynn; Truetsch, Petra; Djafarzadeh, Siamak; Jakob, Stephan M; Seifriz, Franziska; Scherer, Stefan J; Suter, Thomas M; Zuppinger, Christian; Zbinden, Stephan (2012). Cancer therapy modulates VEGF signaling and viability in adult rat cardiac microvascular endothelial cells and cardiomyocytes. Journal of molecular and cellular cardiology, 52(5), pp. 1164-75. Oxford: Elsevier 10.1016/j.yjmcc.2012.01.022

Schmittinger, Christian A; Torgersen, Christian; Luckner, Günter; Schröder, Daniel C H; Lorenz, Ingo; Dünser, Martin W (2012). Adverse cardiac events during catecholamine vasopressor therapy: a prospective observational study. Intensive care medicine, 38(6), pp. 950-958. Berlin: Springer-Verlag 10.1007/s00134-012-2531-2

Jakob, Stephan M; Ruokonen, Esko; Grounds, R Michael; Sarapohja, Toni; Garratt, Chris; Pocock, Stuart J; Bratty, J Raymond; Takala, Jukka; Dexmedetomidine for Long-Term Sedation, Investigators (2012). Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA - the journal of the American Medical Association, 307(11), pp. 1151-60. Chicago, Ill.: American Medical Association 10.1001/jama.2012.304

Jeitziner, M-M; Schwendimann, R; Hamers, J P H; Rohrer, O; Hantikainen, V; Jakob, S M (2012). Assessment of pain in sedated and mechanically ventilated patients: an observational study. Acta anaesthesiologica Scandinavica, 56(5), pp. 645-54. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2012.02660.x

Reintam Blaser, Annika; Malbrain, Manu L N G; Starkopf, Joel; Fruhwald, Sonja; Jakob, Stephan M; De Waele, Jan; Braun, Jan-Peter; Poeze, Martijn; Spies, Claudia (2012). Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems. Intensive care medicine, 38(3), pp. 384-94. Berlin: Springer-Verlag 10.1007/s00134-011-2459-y

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Takala, Jukka (2012). Hemodynamic support: focus on monitoring tools or treatments? Critical care medicine, 40(4), pp. 1359-60. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e318241031b

Vincent, Jean-Louis; Takala, Jukka; Flaatten, Hans (2012). Impact of reimbursement schemes on quality of care: a European perspective. American journal of respiratory and critical care medicine, 185(2), pp. 119-21. New York, N.Y.: American Lung Association 10.1164/rccm.201108-1472ED

Corrêa, Thiago D; Vuda, Madhusudanarao; Blaser, Annika Reintam; Takala, Jukka; Djafarzadeh, Siamak; Dünser, Martin W; Silva, Eliézer; Lensch, Michael; Wilkens, Ludwig; Jakob, Stephan M (2012). Effect of treatment delay on disease severity and need for resuscitation in porcine fecal peritonitis. Critical care medicine, 40(10), pp. 2841-9. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e31825b916b

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Regueira, T; Djafarzadeh, S; Brandt, S; Gorrasi, J; Borotto, E; Porta, F; Takala, J; Bracht, H; Shaw, S; Lepper, P M; Jakob, S M (2012). Oxygen transport and mitochondrial function in porcine septic shock, cardiogenic shock, and hypoxaemia. Acta anaesthesiologica Scandinavica, 56(7), pp. 846-59. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2012.02706.x

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Carrel, T; Englberger, L; Martinelli, M V; Takala, J; Boesch, C; Sigurdadottir, V; Gygax, E; Kadner, A; Mohacsi, P (2012). Continuous flow left ventricular assist devices: a valid option for heart failure patients. Swiss medical weekly, 142, w13701. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2012.13701

Shafighi, Maziar; Olariu, Radu; Brun, Claudio; Fathi, Ali R; Djafarzadeh, Siamak; Jakob, Stephan M; Hunger, Robert E; Banic, Andrej; Constantinescu, Mihai A (2012). The role of androgens on hypoxia-inducible factor (HIF)-1α-induced angiogenesis and on the survival of ischemically challenged skin flaps in a rat model. Microsurgery, 32(6), pp. 475-81. New York, N.Y.: Wiley-Liss 10.1002/micr.21996

Djafarzadeh, Siamak; Vuda, Madhusudanarao; Takala, Jukka; Jakob, Stephan M (2012). Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. PLoS ONE, 7(9), e45195. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0045195

Hedenstierna, Göran; Rothen, Hans Ulrich (2012). Respiratory function during anesthesia: effects on gas exchange. In: Pollock, David M (ed.) Comprehensive Physiology. Comprehensive Physiology: Vol. 2 (pp. 69-96). Wiley 10.1002/cphy.c080111

Garde, A; Giraldo, B F; Jane, R; Latshang, T D; Turk, A J; Hess, T; Bosch, M M; Barthelmes, D; Hefti, J Pichler; Maggiorini, M; Hefti, U; Merz, T M; Schoch, O D; Bloch, K E (2012). Periodic breathing during ascent to extreme altitude quantified by spectral analysis of the respiratory volume signal. IEEE Engineering in Medicine and Biology Society conference proceedings, 2012, pp. 707-710. Piscataway, N.J.: IEEE Service Center

Schmittinger, Christian A.; Torgersen, Christian-Erik; Luckner, Günter; Schröder, Daniel C. H.; Lorenz, Ingo; Dünser, Martin W. (2012). Response to Salvadori et al.: adverse cardiac events during catecholamine therapy: a role for hydrocortisone? Intensive care medicine, 38(10), p. 1726. Springer-Verlag 10.1007/s00134-012-2665-2


Rothen, Hans Ulrich (2011). International standards for programmes of training in intensive care medicine in Europe. Intensive care medicine, 37(3), pp. 385-393. Springer 10.1007/s00134-010-2096-x

Martin-Loeches, I; Lisboa, T; Rhodes, A; Moreno, R P; Silva, E; Sprung, C; Chiche, J D; Barahona, D; Villabon, M; Balasini, C; Pearse, R M; Matos, R; Rello, J; Rothen, Hans Ulrich (2011). Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection. Intensive care medicine, 37(2), pp. 272-283. Springer 10.1007/s00134-010-2078-z

Z'graggen, W J; Brander, L; Tuchscherer, D; Scheidegger, O; Takala, J; Bostock, H (2011). Muscle membrane dysfunction in critical illness myopathy assessed by velocity recovery cycles. Clinical neurophysiology, 122(4), pp. 834-41. Amsterdam: Elsevier 10.1016/j.clinph.2010.09.024

Stricker, K H; Kimberger, O; Brunner, L; Rothen, H U (2011). Patient satisfaction with care in the intensive care unit: can we rely on proxies? Acta anaesthesiologica Scandinavica, 55(2), pp. 149-56. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2010.02293.x

Banz, Vanessa M; Jakob, Stephan M; Inderbitzin, Daniel (2011). Improving Outcome After Major Surgery: Pathophysiological Considerations. Anesthesia and analgesia, 112(5), pp. 1147-55. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/ANE.0b013e3181ed114e

Djafarzadeh, Siamak; Vuda, Madhusudanarao; Takala, Jukka; Ochs, Matthias; Jakob, Stephan M (2011). Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes. Mitochondrion, 11(1), pp. 83-8. Amsterdam: Elsevier 10.1016/j.mito.2010.07.010

Bloechlinger, Stefan; Grander, Wilhelm; Bryner, Juerg; Dünser, Martin W (2011). Left ventricular rotation: a neglected aspect of the cardiac cycle. Intensive care medicine, 37(1), pp. 156-63. Berlin: Springer-Verlag 10.1007/s00134-010-2053-8

Haenggi, Matthias; Barthelmes, Daniel; Ulmer, Hanno; Takala, Jukka; Jakob, Stephan M (2011). Comparison of non-calibrated pulse-contour analysis with continuous thermodilution for cardiac output assessment in patients with induced hypothermia after cardiac arrest. Resuscitation, 82(4), pp. 423-6. Shannon: Elsevier Science Ireland 10.1016/j.resuscitation.2010.12.015

Marbacher, Serge; Sherif, Camillo; Neuschmelting, Volker; Schläppi, Janine-Ai; Takala, Jukka; Jakob, Stephan; Fandino, Javier (2011). Preliminary results of an ICP-controlled subarachnoid hemorrhage rabbit model for the study of delayed cerebral vasospasm. Acta neurochirurgica - supplementa, 110(Pt 1), pp. 163-5. Wien: Springer 10.1007/978-3-7091-0353-1_28

Torgersen, Christian; Dünser, Martin W; Schmittinger, Christian A; Pettilä, Ville; Ruokonen, Esko; Wenzel, Volker; Jakob, Stephan M; Takala, Jukka (2011). Current approach to the haemodynamic management of septic shock patients in European intensive care units: a cross-sectional, self-reported questionnaire-based survey. European journal of anaesthesiology, 28(4), pp. 284-90. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/EJA.0b013e3283405062

Merz, Tobias M; Etter, Reto; Mende, Ludger; Barthelmes, Daniel; Wiegand, Jan; Martinolli, Luca; Takala, Jukka (2011). Risk assessment in the first fifteen minutes: a prospective cohort study of a simple physiological scoring system in the emergency department. Critical care, 15(1), R25. London: BioMed Central 10.1186/cc9972

Hoffmann, M; Bosshard, A; Regli, B; Zimmerli, S; Sendi, P (2011). Intra-aortic balloon pump infection: a neglected nosocomial infection? Journal of hospital infection, 77(1), pp. 91-2. Kidlington, UK: Elsevier 10.1016/j.jhin.2010.07.020

Stricker, Kay H; Sailer, Susanne; Uehlinger, Dominik E; Rothen, Hans U; Zuercher Zenklusen, Regula M; Frick, Sonia (2011). Quality of life 9 years after an intensive care unit stay: A long-term outcome study. Journal of critical care, 26(4), pp. 379-87. New York, N.Y.: Elsevier 10.1016/j.jcrc.2010.11.004

Schmittinger, Christian A; Schär, Ralph; Fung, Christian; Z'graggen, Werner J; Nauer, Claude; Dünser, Martin W; Jung, Simon (2011). Brainstem hemorrhage after neural therapy for decreased libido in a 31-year-old woman. Journal of neurology, 258(7), pp. 1354-5. Heidelberg: Springer-Verlag 10.1007/s00415-011-5921-4

Reinhart, Konrad; Takala, Jukka (2011). Hydroxyethyl starches: what do we still know? Anesthesia and analgesia, 112(3), pp. 507-11. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/ANE.0b013e3182099c49

Wiegand, Jan A; Torgersen, Christian; Bloechlinger, Stefan; Takala, Jukka; Dünser, Martin W (2011). Influenza A(H1N1) infection and severe cardiac dysfunction in adults: A case series. Wiener klinische Wochenschrift, 123(3-4), pp. 120-3. Wien: Springer-Verlag 10.1007/s00508-010-1520-0

Fathi, Ali Reza; Marbacher, Serge; Graupner, Thilo; Wehrli, Felix; Jakob, Stephan M; Schroth, Gerhard; Fandino, Javier (2011). Continuous intrathecal glyceryl trinitrate prevents delayed cerebral vasospasm in the single-SAH rabbit model in vivo. Acta neurochirurgica, 153(8), 1669-75; discussion 1675. Wien: Springer Vienna 10.1007/s00701-011-1049-7

Schmid, P; Mordasini, A; Luginbühl, M; Regli, B; Kohler, H P; Zimmermann, H; Inderbitzin, D; Hirt, A; Lämmle, B; Alberio, L (2011). Low-dose recombinant factor VIIa for massive bleeding: A single centre observational cohort study with 73 patients. Swiss medical weekly, 141, w13213. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2011.13213

Ververidis, D; Van Gils, M; Passath, C; Takala, J; Brander, L (2011). Identification of adequate neurally adjusted ventilatory assist (NAVA) during systematic increases in the NAVA level. IEEE transactions on biomedical engineering, 58(9), pp. 2598-606. New York, N.Y.: Institute of Electrical and Electronics Engineers IEEE 10.1109/TBME.2011.2159790

Takala, Jukka; Ruokonen, Esko; Tenhunen, Jyrki J; Parviainen, Ilkka; Jakob, Stephan M (2011). Early non-invasive cardiac output monitoring in hemodynamically unstable intensive care patients: A multi-center randomized controlled trial. Critical care, 15(3), R148. London: BioMed Central 10.1186/cc10273

Takala, Jukka (2011). Surgery: risky business? Anesthesia and analgesia, 112(4), pp. 745-6. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/ANE.0b013e3181fe495f

Rieke, A; Regli, B; Mattle, H P; Brekenfeld, C; Gralla, J; Schroth, G; Ozdoba, C (2011). Computed tomography angiography (CTA) to prove circulatory arrest for the diagnosis of brain death in the context of organ transplantation. Swiss medical weekly, 141, w13261. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2011.13261

Tuchscherer, Daniel; Z'graggen, Werner J; Passath, Christina; Takala, Jukka; Sinderby, Christer; Brander, Lukas (2011). Neurally adjusted ventilatory assist in patients with critical illness-associated polyneuromyopathy. Intensive care medicine, 37(12), pp. 1951-61. Berlin: Springer-Verlag 10.1007/s00134-011-2376-0

Kessler, Ulf; Grau, Tamar; Gronchi, Fabrizio; Berger, Steffen; Brandt, Sebastian; Bracht, Hendrik; Marcucci, Carlo; Zachariou, Zacharias; Jakob, Stephan M (2011). Comparison of porcine and human coagulation by thrombelastometry. Thrombosis research, 128(5), pp. 477-82. Amsterdam: Elsevier 10.1016/j.thromres.2011.03.013

Dahlqvist, Mats; Hasibeder, Walter R; Dünser, Martin W (2011). Hemodynamic and perfusion end points for volemic resuscitation in sepsis. Shock 34(Suppl 1):34-39, 2010. Shock, 35(4), 434; author reply 434-5. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e318200423f

Shafighi, Maziar; Olariu, Radu; Fathi, Ali R; Djafarzadeh, Siamak; Jakob, Stephan M; Banic, Andrej; Constantinescu, Mihai A (2011). Dimethyloxalylglycine stabilizes HIF-1α in cultured human endothelial cells and increases random-pattern skin flap survival in vivo. Plastic and reconstructive surgery, 128(2), pp. 415-422. Lippincott Williams & Wilkins 10.1097/PRS.0b013e31821e6e69

Torgersen, Christian; Luckner, Günter; Schröder, Daniel C H; Schmittinger, Christian A; Rex, Christopher; Ulmer, Hanno; Dünser, Martin W (2011). Concomitant arginine-vasopressin and hydrocortisone therapy in severe septic shock: association with mortality. Intensive care medicine, 37(9), pp. 1432-7. Berlin: Springer-Verlag 10.1007/s00134-011-2312-3

Dünser, ; Martin, W (2011). Mirror, mirror on the wall: Which is the best vasopressin receptor of them all? Critical care medicine, 39(1), pp. 213-5. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e3181feb630

Jeitziner, Marie-Madlen; Hantikainen, Virpi; Conca, Antoinette; Hamers, Jan P H (2011). Long-term consequences of an intensive care unit stay in older critically ill patients: design of a longitudinal study. BMC Geriatrics, 11, p. 52. London: BioMed Central 10.1186/1471-2318-11-52

Hofmann, Eveline; Marbach, Serge; Jakob, Stephan M; Takala, Jukka; Remonda, Luca; Fandino, Javier (2011). Incidence of vasospasm, outcome, and quality of life after endovascular and surgical treatment of ruptured intracranial aneurysms: results of a single-center prospective study in Switzerland. ISRN vascular medicine, 2011 New York, N.Y.: International Scholarly Research Network ISRN

Berger, David; Rothen, Hans U; Brander, Lukas (2011). Acute Respiratory Distress Syndrome. Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, 11(14), pp. 246-252. Basel: EMH Editores Medicorum Helveticorum

Brander, Lukas; Patak, Michael A (2011). May-Thurner-Syndrom. Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, 11(37), pp. 641-642. Basel: EMH Editores Medicorum Helveticorum


Brunello, Anna-Giulia; Haenggi, Matthias; Wigger, Oliver; Porta, Francesca; Takala, Jukka; Jakob, Stephan M (2010). Usefulness of a clinical diagnosis of ICU-acquired paresis to predict outcome in patients with SIRS and acute respiratory failure. Intensive care medicine, 36(1), pp. 66-74. Berlin: Springer-Verlag 10.1007/s00134-009-1645-7

Bosch, Martina M; Barthelmes, Daniel; Merz, Tobias M; Truffer, Frederic; Knecht, Pascal B; Petrig, Benno; Bloch, Konrad E; Hefti, Urs; Schubiger, Gregor; Landau, Klara (2010). Intraocular pressure during a very high altitude climb. Investigative ophthalmology & visual science, 51(3), pp. 1609-13. Hagerstown, Md.: Association for Research in Vision and Ophthalmology 10.1167/iovs.09-4306

Spirig, Rolf; Djafarzadeh, Siamak; Regueira, Tomas; Shaw, Sidney G; von Garnier, Christophe; Takala, Jukka; Jakob, Stephan M; Rieben, Robert; Lepper, Philipp M (2010). Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions. PLoS ONE, 5(6), e0010983. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0010983

Jakob, Stephan M; Stanga, Zeno (2010). Perioperative metabolic changes in patients undergoing cardiac surgery. Nutrition, 26(4), pp. 349-53. New York, N.Y.: Elsevier 10.1016/j.nut.2009.07.014

Daudel, Fritz; Gorrasi, José; Bracht, Hendrik; Brandt, Sebastian; Krejci, Vladimir; Jakob, Stephan M; Takala, Jukka; Rothen, Hans Ulrich (2010). Effects of lung recruitment maneuvers on splanchnic organ perfusion during endotoxin-induced pulmonary arterial hypertension. Shock, 34(5), pp. 488-94. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e3181e03bfb

Rothen, Hans U; Stricker, Kay H; Heyland, Daren K (2010). Family satisfaction with critical care: measurements and messages. Current opinion in critical care, 16(6), pp. 623-631. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/MCC.0b013e32833e9718

Brügger, Lukas E; Beldi, Guido; Beck, Mario; Porta, Francesca; Bracht, Hendrik; Candinas, Daniel; Takala, Jukka; Jakob, Stephan M (2010). Splanchnic vasoregulation after major abdominal surgery in pigs. World journal of surgery, 34(9), pp. 2057-63. New York, N.Y.: Springer

Barthelmes, D; Jakob, S M; Laitinen, S; Rahikainen, S; Ahonen, H; Takala, J (2010). Effect of site of lactate infusion on regional lactate exchange in pigs. British journal of anaesthesia, 105(5), pp. 627-34. Oxford: Oxford University Press 10.1093/bja/aeq214

Bloch, Konrad E; Latshang, Tsogyal D; Turk, Alexander J; Hess, Thomas; Hefti, Urs; Merz, Tobias M; Bosch, Martina M; Barthelmes, Daniel; Hefti, Jacqueline Pichler; Maggiorini, Marco; Schoch, Otto D (2010). Nocturnal periodic breathing during acclimatization at very high altitude at Mount Muztagh Ata (7,546 m). American journal of respiratory and critical care medicine, 182(4), pp. 562-8. New York, N.Y.: American Lung Association 10.1164/rccm.200911-1694OC

Wyler von Ballmoos, Moritz; Takala, Jukka; Roeck, Margareta; Porta, Francesca; Tueller, David; Ganter, Christoph C; Schröder, Ralph; Bracht, Hendrik; Baenziger, Bertram; Jakob, Stephan M (2010). Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study. Critical care, 14(3), R111. London: BioMed Central 10.1186/cc9060

Passath, Christina; Takala, Jukka; Tuchscherer, Daniel; Jakob, Stephan M; Sinderby, Christer; Brander, Lukas (2010). Physiologic response to changing positive end-expiratory pressure during neurally adjusted ventilatory assist in sedated, critically ill adults. Chest, 138(3), pp. 578-87. Northbrook, Ill.: American College of Chest Physicians 10.1378/chest.10-0286

Dahlqvist, Mats B; Andres, Robert H; Raabe, Andreas; Jakob, Stephan M; Takala, Jukka; Dünser, Martin W (2010). Brain herniation in a patient with apparently normal intracranial pressure: a case report. Journal of medical case reports, 4, p. 297. London: BioMed Central

Daudel, Fritz; Tüller, David; Krähenbühl, Stefanie; Jakob, Stephan M; Takala, Jukka (2010). Pulse pressure variation and volume responsiveness during acutely increased pulmonary artery pressure: an experimental study. Critical care, 14(3), R122. London: BioMed Central 10.1186/cc9080

Torgersen, C; Schmittinger, C A; Takala, J; Jakob, S M; Dünser, M W (2010). The association between early hemodynamic variables and outcome in normothermic comatose patients following cardiac arrest. Acta anaesthesiologica Scandinavica, 54(8), pp. 1027-35. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2010.02273.x

Torgersen, C; Luckner, G; Morgenthaler, N G; Jochberger, S; Schmittinger, C A; Wenzel, V; Hasibeder, W R; Grander, W; Dünser, M W (2010). Plasma copeptin levels before and during exogenous arginine vasopressin infusion in patients with advanced vasodilatory shock. Minerva anestesiologica, 76(11), pp. 905-12. Torino: Minerva Medica

Marbacher, Serge; Sherif, Camillo; Neuschmelting, Volker; Schläppi, Janine-Ai; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2010). Extra-intracranial blood shunt mimicking aneurysm rupture: intracranial-pressure-controlled rabbit subarachnoid hemorrhage model. Journal of neuroscience methods, 191(2), pp. 227-33. Amsterdam: Elsevier 10.1016/j.jneumeth.2010.07.004

Haenggi, Matthias (2010). Anesthesia and analgesia protocol during therapeutic hypothermia after cardiac arrest: it is time to build evidence. Anesthesia and analgesia, 110(5), pp. 1259-60. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/ANE.0b013e3181d77357

Jakob, (2010). Does hypercapnic acidosis preserve mucosal oxygenation during hemorrhage? Shock, 34(6), pp. 649-50. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e3181e86ec8

Jakob, Stephan M; Knuesel, Rafael; Tenhunen, Jyrki J; Pradl, Richard; Takala, Jukka (2010). Increasing abdominal pressure with and without PEEP: effects on intra-peritoneal, intra-organ and intra-vascular pressures. BMC gastroenterology, 10, p. 70. London: BioMed Central 10.1186/1471-230X-10-70

Jeger, Victor; Jakob, Stephan M; Fontana, Stefano; Wolf, Martin; Zimmermann, Heinz; Exadaktylos, Aristomenis K (2010). 500 ml of blood loss does not decrease non-invasive tissue oxygen saturation (StO2) as measured by near infrared spectroscopy - A hypothesis generating pilot study in healthy adult women. Journal of trauma management & outcomes, 4, p. 5. London: BioMed Central 10.1186/1752-2897-4-5

Jakob, Stephan (2010). The effects of mechanical ventilation on hepato-splanchnic perfusion. Current opinion in critical care, 16(2), pp. 165-168. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/MCC.0b013e3283374b1c

Schäfer, Ursi Barandun; Weibel, Lukas; Friedli-Wüthrich, Heidi; Jeitziner, Marie-Madlen (2010). [Knowing what nursing work achieves]. Krankenpflege / Soins infirmiers / Cure infermieristiche, 103(12), pp. 26-8. Bern: Schweizer Berufsverband der Krankenschwestern und Krankenpfleger

Jeitziner, Marie-Madlen; Rohrer, Ottilia; Warmuth, Irene; Herrmann, Luzia; Hirter, Kathrin (2010). [Model project in the island hospital in Berne. Development of evidence-based practice]. Krankenpflege / Soins infirmiers / Cure infermieristiche, 103(10), pp. 18-21. Bern: Schweizer Berufsverband der Krankenschwestern und Krankenpfleger

Rothen, HU (2010). Oxygen: avoid too much of a good thing! European journal of anaesthesiology, 27(6), pp. 493-4. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/EJA.0b013e3283396360

Takala, Jukka (2010). Should we target blood pressure in sepsis? Critical care medicine, 38(10 Suppl), S613-9. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e3181f2430c

Dembinski, Rolf; Hochhausen, Nadine; Terbeck, Sandra; Bickenbach, Johannes; Stadermann, Frederik; Rossaint, Rolf; Kuhlen, Ralf (2010). Effectiveness of nitric oxide during spontaneous breathing in experimental lung injury. Experimental lung research, 36(3), pp. 159-66. New York, N.Y.: Informa Healthcare 10.3109/01902140903225416

Wurz, Jeannie Ann; Rothen, Hans Ulrich; Block, Geke; Kiss, Alexander (2010). Communication. European Society of Intensive Care Medicine

Pichler Hefti, Jacqueline; Risch, Lorenz; Hefti, Urs; Scharrer, Inge; Risch, Gert; Merz, Tobias M; Turk, Alex; Bosch, Martina M; Barthelmess, Daniel; Schoch, Otto; Maggiorini, Marco; Huber, Andreas R (2010). Changes of coagulation parameters during high altitude expedition. Swiss medical weekly, 140(7-8), pp. 111-7. Muttenz: EMH Schweizerischer Ärzteverlag

Torgersen, Christian; Dünser, Martin Wolfgang; Wenzel, Volker; Jochberger, Stefan; Mayr, Viktoria; Schmittinger, Christian A.; Lorenz, Ingo; Schmid, Stefan; Westphal, Martin; Grander, Wilhelm; Luckner, Günter (2010). Comparing two different arginine vasopressin doses in advanced vasodilatory shock: a randomized, controlled, open-label trial. Intensive care medicine, 36(1), pp. 57-65. Springer-Verlag 10.1007/s00134-009-1630-1


Ruokonen, Esko; Parviainen, Ilkka; Jakob, Stephan M; Nunes, Silvia; Kaukonen, Maija; Shepherd, Stephen T; Sarapohja, Toni; Bratty, J Raymond; Takala, Jukka (2009). Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation. Intensive care medicine, 35(2), pp. 282-90. Berlin: Springer-Verlag 10.1007/s00134-008-1296-0

Ganter, Christoph; Buser, Christof; Haenggi, Matthias; Mattes, Hanswilly; Takala, Jukka; Jakob, Stephan (2009). Inverse thermodilution with conventional pulmonary artery catheters for the assessment of cerebral, hepatic, renal, and femoral blood flow. Shock, 32(2), pp. 194-200. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e318194c73a

Brander, Lukas; Leong-Poi, Howard; Beck, Jennifer; Brunet, Fabrice; Hutchison, Stuart J; Slutsky, Arthur S; Sinderby, Christer (2009). Titration and implementation of neurally adjusted ventilatory assist in critically ill patients. Chest, 135(3), pp. 695-703. Northbrook, Ill.: American College of Chest Physicians 10.1378/chest.08-1747

Neuschmelting, Volker; Fathi, Ali-Reza; Hidalgo Staub, Eveline Teresa; Marbacher, Serge; Schroth, Gerhard; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2009). Norepinephrine-induced hypertension dilates vasospastic basilar artery after subarachnoid haemorrhage in rabbits. Acta neurochirurgica, 151(5), pp. 487-93. Wien: Springer Vienna 10.1007/s00701-009-0287-4

Brandt, S; Regueira, T; Bracht, H; Porta, F; Takala, J; Hiltebrand, LB; Beldi, G; Lepper, MP; Brügger, LE; Kessler, U; Jakob St, M (2009). Effect of fluid resuscitation on mortality and organ function in experimental sepsis models. Critical care, 13(6), R186. London: BioMed Central 10.1186/cc8179

von Gunten, Stephan; Jakob, Stephan M; Geering, Barbara; Takala, Jukka; Simon, Hans-Uwe (2009). Different patterns of Siglec-9-mediated neutrophil death responses in septic shock. Shock, 32(4), pp. 386-92. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e3181a1bc98

Stricker, Kay H; Takala, Jukka; Hullin, Roger; Ganter, Christoph C (2009). When drugs disappear from the patient: elimination of intravenous medication by hemodiafiltration. Anesthesia and analgesia, 109(5), pp. 1640-3. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/ANE.0b013e3181b9db63

Stricker, Kay H; Kimberger, Oliver; Schmidlin, Kurt; Zwahlen, Marcel; Mohr, Ulrike; Rothen, Hans U (2009). Family satisfaction in the intensive care unit: what makes the difference? Intensive care medicine, 35(12), pp. 2051-9. Berlin: Springer-Verlag 10.1007/s00134-009-1611-4

Michel, P; Arnold, M; Hungerbühler, H-J; Müller, F; Staedler, C; Baumgartner, R W; Georgiadis, D; Lyrer, P; Mattle, H P; Sztajzel, R; Weder, B; Tettenborn, B; Nedeltchev, K; Engelter, S; Weber, S A; Basciani, R; Fandino, J; Fluri, F; Stocker, R; Keller, E; ... (2009). Decompressive craniectomy for space occupying hemispheric and cerebellar ischemic strokes: Swiss recommendations. International journal of stroke, 4(3), pp. 218-23. Oxford: Blackwell Publishing 10.1111/j.1747-4949.2009.00283.x

Haenggi, Matthias; Ypparila-Wolters, Heidi; Buerki, Sarah; Schlauri, Rebekka; Korhonen, Ilkka; Takala, Jukka; Jakob, Stephan M (2009). Auditory event-related potentials, bispectral index, and entropy for the discrimination of different levels of sedation in intensive care unit patients. Anesthesia and analgesia, 109(3), pp. 807-16. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/ane.0b013e3181acc85d

Neuschmelting, Volker; Marbacher, Serge; Fathi, Ali-Reza; Jakob, Stephan M; Fandino, Javier (2009). Elevated level of endothelin-1 in cerebrospinal fluid and lack of nitric oxide in basilar arterial plasma associated with cerebral vasospasm after subarachnoid haemorrhage in rabbits. Acta neurochirurgica, 151(7), 795-801; discussion 801-2. Wien: Springer Vienna 10.1007/s00701-009-0350-1

Sherif, Camillo; Marbacher, Serge; Fandino, Javier (2009). High-resolution three-dimensional 3 T magnetic resonance angiography for the evaluation of experimental aneurysm in the rabbit. Neurological research, 31(8), pp. 869-72. Leeds: Maney 10.1179/174313209X393979

Bloch, Konrad E; Turk, Alexander J; Maggiorini, Marco; Hess, Thomas; Merz, Tobias; Bosch, Martina M; Barthelmes, Daniel; Hefti, Urs; Pichler, Jacqueline; Senn, Oliver; Schoch, Otto D (2009). Effect of ascent protocol on acute mountain sickness and success at Muztagh Ata, 7546 m. High altitude medicine & biology, 10(1), pp. 25-32. Larchmont, N.Y.: Mary Ann Liebert 10.1089/ham.2008.1043

Barthelmes, Daniel; Parviainen, Ilkka; Vainio, Pauli; Vanninen, Ritva; Takala, Jukka; Ikonen, Aki; Tueller, David; Jakob, Stephan M (2009). Assessment of splanchnic blood flow using magnetic resonance imaging. European journal of gastroenterology & hepatology, 21(6), pp. 693-700. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/MEG.0b013e32831a86e0

Bosch, Martina M; Merz, Tobias M; Barthelmes, Daniel; Petrig, Benno L; Truffer, Frederic; Bloch, Konrad E; Turk, Alex; Maggiorini, Marco; Hess, Thomas; Schoch, Otto D; Hefti, Urs; Sutter, Florian K P; Pichler, Jacqueline; Huber, Andreas; Landau, Klara (2009). New insights into ocular blood flow at very high altitudes. Journal of applied physiology, 106(2), pp. 454-60. Bethesda, Md.: American Physiological Society 10.1152/japplphysiol.90904.2008

Brander, Lukas; Sinderby, Christer; Lecomte, François; Leong-Poi, Howard; Bell, David; Beck, Jennifer; Tsoporis, James N; Vaschetto, Rosanna; Schultz, Marcus J; Parker, Thomas G; Villar, Jesús; Zhang, Haibo; Slutsky, Arthur S (2009). Neurally adjusted ventilatory assist decreases ventilator-induced lung injury and non-pulmonary organ dysfunction in rabbits with acute lung injury. Intensive care medicine, 35(11), pp. 1979-89. Berlin: Springer 10.1007/s00134-009-1626-x

Brander, Lukas; Haltmeier, Tobias; Suter, Anna; Studer, Peter; Inderbitzin, Daniel; Candinas, Daniel; Vogt, Andreas; Henzen, Christoph; Takala, Jukka; Jakob, Stephan M (2009). Peri-operative adrenocortical response to low-dose (1 microg) ACTH and relation to postoperative complications in patients undergoing elective abdominal surgery. Surgery, 146(1), pp. 88-99. New York, N.Y.: Elsevier 10.1016/j.surg.2009.01.018

Regueira, T; Andresen, M; Djafarzadeh, S (2009). [Mitochondrial dysfunction during sepsis, impact and possible regulating role of hypoxia-inducible factor-1alpha]. Medicina intensiva, 33(8), pp. 385-92. Madrid: IDEPSA, International de Ediciones y Publicaciones, S.A. 10.1016/j.medin.2008.10.002

Regueira, Tomas; Lepper, Philipp M; Brandt, Sebastian; Ochs, Matthias; Vuda, Madhusudanarao; Takala, Jukka; Jakob, Stephan M; Djafarzadeh, Siamak (2009). Hypoxia inducible factor-1 alpha induction by tumour necrosis factor-alpha, but not by toll-like receptor agonists, modulates cellular respiration in cultured human hepatocytes. Liver international, 29(10), pp. 1582-92. Oxford: Blackwell Munksgaard 10.1111/j.1478-3231.2009.02109.x

Daudel, Fritz; Kessler, Ulf; Folly, Hélène; Lienert, Jasmin S; Takala, Jukka; Jakob, Stephan M (2009). Thromboelastometry for the assessment of coagulation abnormalities in early and established adult sepsis: a prospective cohort study. Critical care, 13(2), R42. London: BioMed Central 10.1186/cc7765

Dünser, Martin W; Takala, Jukka; Ulmer, Hanno; Mayr, Viktoria D; Luckner, Günter; Jochberger, Stefan; Daudel, Fritz; Lepper, Philipp; Hasibeder, Walter R; Jakob, Stephan M (2009). Arterial blood pressure during early sepsis and outcome. Intensive care medicine, 35(7), pp. 1225-33. Berlin: Springer-Verlag 10.1007/s00134-009-1427-2

Dullenkopf, Alexander; Rothen, Hans U (2009). What patients and relatives expect from an intensivist--the Swiss side of a European survey. Swiss medical weekly, 139(3-4), pp. 47-51. Muttenz: EMH Schweizerischer Ärzteverlag

Dünser, Martin W; Ruokonen, Esko; Pettilä, Ville; Ulmer, Hanno; Torgersen, Christian; Schmittinger, Christian A; Jakob, Stephan; Takala, Jukka (2009). Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial. Critical care, 13(6), R181. London: BioMed Central 10.1186/cc8167

Dünser, Martin W; Bataar, Otgon; Tsenddorj, Ganbat; Lundeg, Ganbold; Jochberger, Stefan; Jakob, Stephan (2009). Intensive care medicine in Mongolia's 3 largest cities: outlining the needs. Journal of critical care, 24(3), 469.e1-6. New York, N.Y.: Elsevier 10.1016/j.jcrc.2008.06.014

Haenggi, Matthias; Ypparila-Wolters, Heidi; Hauser, Kathrin; Caviezel, Claudio; Takala, Jukka; Korhonen, Ilkka; Jakob, Stephan M (2009). Intra- and inter-individual variation of BIS-index and Entropy during controlled sedation with midazolam/remifentanil and dexmedetomidine/remifentanil in healthy volunteers: an interventional study. Critical care, 13(1), R20. London: BioMed Central 10.1186/cc7723

Torgersen, Christian; Schmittinger, Christian A; Wagner, Sarah; Ulmer, Hanno; Takala, Jukka; Jakob, Stephan M; Dünser, Martin W (2009). Hemodynamic variables and mortality in cardiogenic shock: a retrospective cohort study. Critical care, 13(5), R157. London: BioMed Central 10.1186/cc8114

Farese, Stefan; Jakob, Stephan M; Kalicki, Robert; Frey, Felix J; Uehlinger, Dominik E (2009). Treatment of acute renal failure in the intensive care unit: lower costs by intermittent dialysis than continuous venovenous hemodiafiltration. Artificial organs, 33(8), pp. 634-40. Malden, Mass.: Wiley-Blackwell 10.1111/j.1525-1594.2009.00794.x

Jakob, Stephan (2009). Septic shock resuscitation: what goals and how to achieve them? Critical care, 13(3), p. 147. London: BioMed Central 10.1186/cc7870

Arnberger, Michael; Vogt, Andreas; Studer, Peter; Inderbitzin, Daniel; Pulver, Carole; Röhrig, Bernd; Jakob, Stephan M; Greif, Robert (2009). Evaluation of physical and mental recovery status after elective liver resection. European journal of anaesthesiology, 26(7), pp. 559-65. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/EJA.0b013e328328f552

Jakob, Stephan M; Takala, Jukka (2009). Physical and occupational therapy during sedation stops. Lancet, 373(9678), pp. 1824-6. London: Elsevier 10.1016/S0140-6736(09)60866-7

Takala, Jukka; Jakob, Stephan M (2009). Shedding light on microcirculation? Intensive care medicine, 35(3), pp. 394-6. Berlin: Springer-Verlag 10.1007/s00134-008-1386-z

Jakob, Stephan M; Parviainen, Ilkka; Ruokonen, Esko; Hinder, Raffael; Uusaro, Ari; Takala, Jukka (2009). Increased splanchnic oxygen extraction because of routine nursing procedures. Critical care medicine, 37(2), pp. 483-9. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e3181958821

Porta, Francesca; Bracht, Hendrik; Weikert, Christian; Beck, Mario; Takala, Jukka; Brandt, Sebastian; Hiltebrand, Luzius B; Jakob, Stephan M (2009). Effects of endotoxin and catecholamines on hepatic mitochondrial respiration. Inflammation, 32(5), pp. 315-21. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10753-009-9138-y

Takala, Jukka (2009). Better conduct of clinical trials: the control group in critical care trials. Critical care medicine, 37(1 Suppl), S80-90. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e3181922bf4

Lecomte, François; Brander, Lukas; Jalde, Fredrick; Beck, Jennifer; Qui, Haibo; Elie, Caroline; Slutsky, Arthur S; Brunet, Fabrice; Sinderby, Christer (2009). Physiological response to increasing levels of neurally adjusted ventilatory assist (NAVA). Respiratory physiology & neurobiology, 166(2), pp. 117-24. Kidlington, UK: Elsevier 10.1016/j.resp.2009.02.015

Dünser, Martin W; Schmittinger, Christian A; Torgersen, Christian (2009). Copeptin and the transplanted kidney: friends or foes? Transplantation, 88(4), pp. 455-6. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/TP.0b013e3181b050a2

Merz, T M; Finfer, S (2009). Intensive insulin treatment. Minerva anestesiologica, 75(12), pp. 703-9. Torino: Minerva Medica

Maier, Stephan; Holz-Hölzl, Carmen; Pajk, Werner; Ulmer, Hanno; Hengl, Christian; Dünser, Martin; Haas, Thorsten; Velik-Salchner, Corinna; Fries, Dietmar; Greiner, Andreas; Hasibeder, Walter; Knotzer, Hans (2009). Microcirculatory parameters after isotonic and hypertonic colloidal fluid resuscitation in acute hemorrhagic shock. Journal of trauma - injury, infection, and critical care, 66(2), pp. 337-45. Baltimore, Md.: Lippincott, Williams, & Wilkins 10.1097/TA.0b013e31817dac66

Müller, Lionel; Myers, J.; Kottman, W.; Luchinger, R.; Dubach, P. (2009). Long-term myocardial adaptations after cardiac rehabilitation in heart failure: a randomized six-year evaluation using magnetic resonance imaging. Clinical rehabilitation, 23(11), pp. 986-994. Sage 10.1177/0269215509339003


Nyberg, A; Jakob, S M; Seeman-Lodding, H; Porta, F; Bracht, H; Bischofberger, H; Jern, C; Takala, J; Aneman, A (2008). Time- and dose-related regional fluxes of tissue-type plasminogen activator in anesthetized endotoxemic pigs. Acta anaesthesiologica Scandinavica, 52(1), pp. 57-64. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2007.01481.x

Beck, Jennifer; Brander, Lukas; Slutsky, Arthur S; Reilly, Maureen C; Dunn, Michael S; Sinderby, Christer (2008). Non-invasive neurally adjusted ventilatory assist in rabbits with acute lung injury. Intensive care medicine, 34(2), pp. 316-23. Berlin: Springer 10.1007/s00134-007-0882-x

Etter, Reto; Ludwig, Roger; Lersch, Friedrich; Takala, Jukka; Merz, Tobias M (2008). Early prognostic value of the medical emergency team calling criteria in patients admitted to intensive care from the emergency department. Critical care medicine, 36(3), pp. 775-81. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0B013E3181643C15

Bracht, Hendrik; Krejci, Vladimir; Hiltebrand, Luzius; Brandt, Sebastian; Sigurdsson, Gisli; Ali, Syed Z; Takala, Jukka; Jakob, Stephan M (2008). Orthogonal polarization spectroscopy to detect mesenteric hypoperfusion. Intensive care medicine, 34(10), pp. 1883-90. Berlin: Springer-Verlag 10.1007/s00134-008-1130-8

Taniguchi, Yoshie; Bracht, Hendrik; Porta, Francesca; Krejci, Vladimir; Ali, Sayed Z; Beck, Mario; Mettler, Daniel; Takala, Jukka; Jakob, Stephan M (2008). Thermodilution and esophageal Doppler ultrasound in the assessment of blood flow changes induced by endotoxin and dobutamine. Journal of trauma - injury, infection, and critical care, 65(1), pp. 175-82. Baltimore, Md.: Lippincott, Williams, & Wilkins 10.1097/TA.0b013e31815eb0ff

Ali, Syed Z; Bracht, Hendrik; Krejci, Vladimir; Beck, Mario; Stalder, Michael; Hiltebrand, Luzius; Takala, Jukka; Brandt, Sebastian; Jakob, Stephan M (2008). The immediate and sustained effects of volume challenge on regional blood flows in pigs. Anesthesia and analgesia, 106(2), 595-600, table of contents. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/ane.0b013e31816064d2

Regueira, Tomas; Bänziger, Bertram; Djafarzadeh, Siamak; Brandt, Sebastian; Gorrasi, Jose; Takala, Jukka; Lepper, Philipp M; Jakob, Stephan M (2008). Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration. Critical care, 12(4), R88. London: BioMed Central 10.1186/cc6956

Guglielmi, S; Merz, T M; Gugger, M; Suter, C; Nicod, L P (2008). Acute respiratory distress syndrome secondary to antisynthetase syndrome is reversible with tacrolimus. European respiratory journal, 31(1), pp. 213-7. Sheffield, UK: European Respiratory Society 10.1183/09031936.00014707

Marbacher, Serge; Neuschmelting, Volker; Graupner, Thilo; Jakob, Stephan M; Fandino, Javier (2008). Prevention of delayed cerebral vasospasm by continuous intrathecal infusion of glyceroltrinitrate and nimodipine in the rabbit model in vivo. Intensive care medicine, 34(5), pp. 932-8. Berlin: Springer-Verlag 10.1007/s00134-008-0995-x

Taussky, Philipp; Widmer, Hans Rudolf; Takala, Jukka; Fandino, Javier (2008). Outcome after acute traumatic subdural and epidural haematoma in Switzerland: a single-centre experience. Swiss medical weekly, 138(19-20), pp. 281-5. Muttenz: EMH Schweizerischer Ärzteverlag

Jakob, Stephan (2008). It makes a difference! Wiener klinische Wochenschrift, 120(19-20), pp. 581-2. Wien: Springer Vienna 10.1007/s00508-008-1082-6

Hänggi, Matthias; Ypparila-Wolters, Heidi; Bieri, Christine; Steiner, Carola; Takala, Jukka; Korhonen, Ilkka; Jakob, Stephan M (2008). Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study. Critical care, 12(5), R119. London: BioMed Central 10.1186/cc7015

Takala, Jukka; Dellinger, R Philip; Koskinen, Kati; St Andre, Arthur; Read, Martyn; Levy, Mitchell; Jakob, Stephan M; Mello, Patricia Veiga C; Friolet, Raymond; Ruokonen, Esko (2008). Development and simultaneous application of multiple care protocols in critical care: a multicenter feasibility study. Intensive care medicine, 34(8), pp. 1401-10. Berlin: Springer-Verlag 10.1007/s00134-008-1084-x

Moerer, Onnen; Beck, Jennifer; Brander, Lukas; Costa, Roberta; Quintel, Michael; Slutsky, Arthur S; Brunet, Fabrice; Sinderby, Christer (2008). Subject-ventilator synchrony during neural versus pneumatically triggered non-invasive helmet ventilation. Intensive care medicine, 34(9), pp. 1615-23. Berlin: Springer 10.1007/s00134-008-1163-z

Merz, Tobias M; Schär, Pascale; Bühlmann, Michael; Takala, Jukka; Rothen, Hans U (2008). Resource use and outcome in critically ill patients with hematological malignancy: a retrospective cohort study. Critical care, 12(3), R75. London: BioMed Central 10.1186/cc6921

Pichler, J; Risch, L; Hefti, U; Merz, T M; Turk, A J; Bloch, K E; Maggiorini, M; Hess, T; Barthelmes, D; Schoch, O D; Risch, G; Huber, A R (2008). Glomerular filtration rate estimates decrease during high altitude expedition but increase with Lake Louise acute mountain sickness scores. Acta physiologica, 192(3), pp. 443-50. Oxford: Blackwell Publishing 10.1111/j.1748-1716.2007.01758.x

Triantafilou, Martha; Lepper, Philipp M; Briault, Caspar David; Ahmed, Mohamed Abd Elrahman; Dmochowski, Josh M; Schumann, Christian; Triantafilou, Kathy (2008). Chemokine receptor 4 (CXCR4) is part of the lipopolysaccharide "sensing apparatus". European journal of immunology, 38(1), pp. 192-203. Weinheim: Wiley-VCH 10.1002/eji.200636821

Bosch, Martina M; Barthelmes, Daniel; Merz, Tobias M; Bloch, Konrad E; Turk, Alexander J; Hefti, Urs; Sutter, Florian K P; Maggiorini, Marco; Wirth, Maria G; Schoch, Otto D; Landau, Klara (2008). High incidence of optic disc swelling at very high altitudes. Archives of ophthalmology, 126(5), pp. 644-50. Chicago, Ill.: American Medical Association 10.1001/archopht.126.5.644

Suter, Peter M; Takala, Jukka (2008). Science, medicine and industry: are we getting out of the black hole in sepsis research? Intensive care medicine, 34(11), pp. 1950-4. Berlin: Springer-Verlag 10.1007/s00134-008-1302-6

Vincent, Jean-Louis; Pinsky, Michael R; Sprung, Charles L; Levy, Mitchell; Marini, John J; Payen, Didier; Rhodes, Andrew; Takala, Jukka (2008). The pulmonary artery catheter: in medio virtus. Critical care medicine, 36(11), pp. 3093-6. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e31818c10c7

Rothen, Hans Ulrich; Takala, Jukka (2008). Can outcome prediction data change patient outcomes and organizational outcomes? Current opinion in critical care, 14(5), pp. 513-9. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/MCC.0b013e32830864e9

Dünser, Martin W; Westphal, Martin (2008). Arginine vasopressin in vasodilatory shock: effects on metabolism and beyond. Current opinion in anaesthesiology, 21(2), pp. 122-7. Hagerstown, Md.: Lippincott Williams & Wilkins

Rohrer, Ottilia; Jeitziner, Marie-Madlen (2008). [Practical and every-day symbolism]. Krankenpflege / Soins infirmiers / Cure infermieristiche, 101(10), pp. 30-2. Bern: Schweizer Berufsverband der Krankenschwestern und Krankenpfleger

Lötscher, S; Wermelinger, VR; Jakob, SM; Merz, TM (2008). Hämophagozytose-Syndrom mit massivem capillary leak. Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, -8(46), pp. 898-900. Basel: EMH Editores Medicorum Helveticorum

Brandt, S; Takala, J; Lepper, PM (2008). The role of hypoxia and inflammation in the expression and regulation of proteins regulating iron metabolism. In: , (ed.) Yearbook of Intensive Care and Emergency Medicine (pp. 473-480). Heidelberg: Springer Verlag

Brander, L; Slutsky, AS (2008). Invasive Mechanical Ventilation. In: Albert RK, Spiro SG (ed.) Clinical Respiratory Medicine (231 256). Mosby

Lutz, JA; Ganter, CC; Angst, E; Worni, M; Gloor, B (2008). Neue Entwicklungen des Managements bei schwerer akuter Pankreatitis. In: Intensivmedizin, Kompendium und Repetitorium zur interdisziplinären Weiter- und Fortbildung (pp. 1-20). Heidelberg: Verlagsgruppe Hüthig Jehle Rehm

Merz, TM; Finfer, S (2008). Crystalloids versus colloids versus albumin: where do we stand? In: Kuhlen R, Moreno R (ed.) Controversies in Intensive Care Medicine (xx-xx). European Society of Intensive Care Medicine

Regli, B; Spescha, P; Peter, C (2008). Labormedizin bei Organtransplantationen. 2. Teil: Labormedizin beim (potentiellen) Organspender ein ethisches Problem? Pipette - Swiss laboratory medicine(3), pp. 6-9. Muttenz: EMH Schweizerischer Ärzteverlag AG

Regueira, Tomas Emilio; Jakob, Stephan; Djafarzadeh, Siamak (2008). Regulation of mitochondrial function by hypoxia and inflammation in sepsis: A putative role for hypoxia inducible factor. In: Vincent, Jean-Louis (ed.) Yearbook of Intensive Care and Emergency Medicine 2008 (pp. 385-394). Heidelberg: Springer 10.1007/978-3-540-77290-3_36

Wurz, J (2008). ESICM tackles tough issue during Silver Anniversary in Berlin. In: ICU MANAGEMENT.

Brander, L (2008). NAVA--oder wenn der Patient das Beatmungsgerät steuert. Neurally adjusted ventilatory assist: Ein grundlegend neues Konzept in der mechanischen Beatmung. Medical journal TMJ(6), pp. 19-22. Neuhausen (CH): Rosenfluh

Barthelmes, Daniel; Sutter, Florian K P; Gillies, Mark C (2008). Differential optical densities of intraretinal spaces. Investigative ophthalmology & visual science, 49(8), pp. 3529-34. Hagerstown, Md.: Association for Research in Vision and Ophthalmology 10.1167/iovs.07-1320

Rothen, HU (2008). Optimisation of patient process and workflow. In: Kuhlen R, Moreno R (ed.) Controversies in Intensive Care Medicine (323-). Berlin: MWV Medizinisch Wissenschaftliche Verlagsgesellschaft

Morelli, A.; Ertmer, C.; Lange, M.; Dünser, M.; Rehberg, S.; Van Aken, H.; Pietropaoli, P.; Westphal, M. (2008). Effects of short-term simultaneous infusion of dobutamine and terlipressin in patients with septic shock: the DOBUPRESS study. British journal of anaesthesia, 100(4), pp. 494-503. Oxford University Press 10.1093/bja/aen017


Müller, Lionel; Myers, Jonathan; Kottman, Wilhard; Oswald, Ulrike; Boesch, Claudia; Arbrol, Nayana; Dubach, Paul (2007). Exercise capacity, physical activity patterns and outcomes six years after cardiac rehabilitation in patients with heart failure. Clinical rehabilitation, 21(10), pp. 923-931. Sage 10.1177/0269215507079097

Plock, Jan; Frese, Steffen; Keogh, Adrian; Bisch-Knaden, Sonja; Ayuni, Erick; Corazza, Nadia; Weikert, Christian; Jakob, Stephan; Erni, Dominique; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel; Stroka, Deborah (2007). Activation of non-ischemic, hypoxia-inducible signalling pathways up-regulate cytoprotective genes in the murine liver. Journal of hepatology, 47(4), pp. 538-45. Amsterdam: Elsevier 10.1016/j.jhep.2007.04.016

Stricker, Kay H; Niemann, Steffen; Bugnon, Sophie; Wurz, Jeannie; Rohrer, Ottilia; Rothen, Hans U (2007). Family satisfaction in the intensive care unit: cross-cultural adaptation of a questionnaire. Journal of critical care, 22(3), pp. 204-11. New York, N.Y.: Elsevier 10.1016/j.jcrc.2006.12.008

Krejci, Vladimir; Hiltebrand, Luzius B; Jakob, Stephan M; Takala, Jukka; Sigurdsson, Gisli H (2007). Vasopressin in septic shock: effects on pancreatic, renal, and hepatic blood flow. Critical care, 11(6), R129. London: BioMed Central 10.1186/cc6197

Jakob, Stephan M; Parviainen, Ilkka; Ruokonen, Esko; Kogan, Alexander; Takala, Jukka (2007). TONOMETRY REVISITED: PERFUSION-RELATED, METABOLIC, AND RESPIRATORY COMPONENTS OF GASTRIC MUCOSAL ACIDOSIS IN ACUTE CARDIORESPIRATORY FAILURE. Shock, 29(5), pp. 543-548. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e31815d0c10

Jakob, Stephan M; Lubszky, Szabina; Friolet, Raymond; Rothen, Hans Ulrich; Kolarova, Anna; Takala, Jukka (2007). Sedation and weaning from mechanical ventilation: effects of process optimization outside a clinical trial. Journal of critical care, 22(3), pp. 219-28. New York, N.Y.: Elsevier 10.1016/j.jcrc.2007.01.001

Knuesel, Rafael; Takala, Jukka; Brander, Lukas; Haenggi, Matthias; Bracht, Hendrik; Porta, Francesca; Jakob, Stephan M (2007). Intraperitoneal microdialysis: critique of an editorial. Critical care medicine, 35(7), 1802; discussion 1802. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/01.CCM.0000269345.99949.3D

Hiltebrand, Luzius B; Krejci, Vladimir; Jakob, Stephan M; Takala, Jukka; Sigurdsson, Gisli H (2007). Effects of vasopressin on microcirculatory blood flow in the gastrointestinal tract in anesthetized pigs in septic shock. Anesthesiology, 106(6), pp. 1156-67. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.anes.0000267599.02140.86

Contaldo, C; Harder, Y; Plock, J; Banic, A; Jakob, S M; Erni, D (2007). The influence of local and systemic preconditioning on oxygenation, metabolism and survival in critically ischaemic skin flaps in pigs. Journal of plastic, reconstructive & aesthetic surgery, 60(11), pp. 1182-92. Amsterdam: Elsevier 10.1016/j.bjps.2007.02.011

Bracht, Hendrik; Hänggi, Matthias; Jeker, Barbara; Wegmüller, Ninja; Porta, Francesca; Tüller, David; Takala, Jukka; Jakob, Stephan M (2007). Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study. Critical care, 11(1), R2. London: BioMed Central 10.1186/cc5144

Wurz, Jeannie; Regli, Bruno (2007). In one ear and out the other: communication barriers as a risk factor for critical incidents. Anesthesia and analgesia, 104(6), pp. 1319-21. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/01.ane.0000264080.34899.86

Rothen, Hans U; Stricker, Kay; Einfalt, Johanna; Bauer, Peter; Metnitz, Philip G H; Moreno, Rui P; Takala, Jukka (2007). Variability in outcome and resource use in intensive care units. Intensive care medicine, 33(8), pp. 1329-36. Berlin: Springer-Verlag 10.1007/s00134-007-0690-3

Appelberg, Jonas; Pavlenko, Tatjana; Bergman, Henrik; Rothen, Hans Ulrich; Hedenstierna, Göran (2007). Lung aeration during sleep. Chest, 131(1), pp. 122-9. Northbrook, Ill.: American College of Chest Physicians 10.1378/chest.06-0359

von Eynatten, M; Lepper, P M; Liu, D; Lang, K; Baumann, M; Nawroth, P P; Bierhaus, A; Dugi, K A; Heemann, U; Allolio, B; Humpert, P M (2007). Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with type 2 diabetes or coronary artery disease. Diabetologia, 50(9), pp. 1930-7. Heidelberg: Springer 10.1007/s00125-007-0743-8

Triantafilou, Martha; Gamper, Frederick G J; Lepper, Philipp M; Mouratis, Marios Angelos; Schumann, Christian; Harokopakis, Evlambia; Schifferle, Robert E; Hajishengallis, George; Triantafilou, Kathy (2007). Lipopolysaccharides from atherosclerosis-associated bacteria antagonize TLR4, induce formation of TLR2/1/CD36 complexes in lipid rafts and trigger TLR2-induced inflammatory responses in human vascular endothelial cells. Cellular microbiology, 9(8), pp. 2030-9. Oxford: Blackwell 10.1111/j.1462-5822.2007.00935.x

von Eynatten, Maximilian; Humpert, Per M; Bluemm, Annabelle; Lepper, Philipp M; Hamann, Andreas; Allolio, Bruno; Nawroth, Peter P; Bierhaus, Angelika; Dugi, Klaus A (2007). High-molecular weight adiponectin is independently associated with the extent of coronary artery disease in men. Atherosclerosis, 199(1), pp. 123-128. Amsterdam: Elsevier 10.1016/j.atherosclerosis.2007.10.002

von Eynatten, Maximilian; Lepper, Philipp M; Humpert, Per M (2007). Total and high-molecular weight adiponectin in relation to metabolic variables at baseline and in response to an exercise treatment program: comparative evaluation of three assays: response to Bluher et al. Diabetes care, 30(7), e67; author reply e68. Alexandria, Va.: American Diabetes Association 10.2337/dc06-1362

Lepper, Philipp M; von Eynatten, Maximilian; Humpert, Per M; Triantafilou, Martha; Triantafilou, Kathy (2007). Toll-like receptor polymorphisms and carotid artery intima-media thickness. Stroke, 38(7), e50. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/STROKEAHA.107.487058

Fandino, J; Fathi, A R; Graupner, T; Jakob, S; Landolt, H (2007). [Perspectives in the treatment of subarachnoid-hemorrhage-induced cerebral vasospasm]. Neurocirugía, 18(1), pp. 16-27. Madrid: Siglo

Takala, Jukka (2007). Hypoxemia due to increased venous admixture: influence of cardiac output on oxygenation. Intensive care medicine, 33(5), pp. 908-11. Berlin: Springer Berlin Heidelberg 10.1007/s00134-007-0546-x

Takala, Jukka (2007). Hemodynamic management of the critically ill patient: craft meets science. Current opinion in critical care, 13(5), pp. 519-20. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/MCC.0b013e3282f00f1f

Hasman, A; Askham, A; Rothen, HU; Berg, P; Bion, JF; Reay, H (2007). The views of patients and relatives of what makes a good intensivist: a European survey. Intensive care medicine, 33(11), pp. 1913-1920. Berlin: Springer 10.1007/s00134-007-0799-4

Morelli, Andrea; Lange, Matthias; Ertmer, Christian; Dünser, Martin; Rehberg, Sebastian; Bachetoni, Alessandra; D'Alessandro, Marladomenica; Van Aken, Hugo; Guarracino, Fabio; Pietropaoli, Paolo; Traber, Daniel L; Westphal, Martin (2007). SHORT-TERM EFFECTS OF PHENYLEPHRINE ON SYSTEMIC AND REGIONAL HEMODYNAMICS IN PATIENTS WITH SEPTIC SHOCK: A CROSSOVER PILOT STUDY. Shock, 29(4), pp. 446-451. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e31815810ff

Trautmann, M; Lepper, PM; Blessing, J; Schutz, T; Gfrörer, S; Regnath, T; Reiter, W; Rieger, T; Wellinghausen, N; Essig, A (2007). In-vitro-Empfindlichkeit von Piperacillin-nicht-sensiblen Enterobakteriazeen und Pseudomonas aeruginosa gegenüber Piperacillin/Tazobactam im Vergleich zu Piperacillin/Sulbactam. Chemotherapie-Journal(16), pp. 123-130. Stuttgart: Wissenschaftliche Verlagsgesellschaft mbH

Etter, Reto; Klammer, G; Probst, P; Tamm, M; Gambazzi, F; Borer, H (2007). Unexplained chronic dyspnea in a young woman. Respiration, 74(5), pp. 586-587. Karger 10.1159/000088685

Mayr, V. D.; Luckner, G.; Jochberger, S.; Wenzel, V.; Hasibeder, W. R.; Dünser, M. W. (2007). Vasopressin as a rescue vasopressor agent. Anaesthesist, 56(10), pp. 1017-1023. Springer-Medizin-Verlag 10.1007/s00101-007-1227-4


Etter, Reto; Brutsche, M; Huegli, R W; Borer, H (2006). [A rare cause of dyspnea on exertion. A 76-year-old retired woman]. Praxis - schweizerische Rundschau für Medizin, 95(35), pp. 1332-1334. Huber

Porta, Francesca; Takala, Jukka; Weikert, Christian; Bracht, Hendrik; Kolarova, Anna; Lauterburg, Bernhard H; Borotto, Erika; Jakob, Stephan M (2006). Effects of prolonged endotoxemia on liver, skeletal muscle and kidney mitochondrial function. Critical care, 10(4), R118. London: BioMed Central 10.1186/cc5013

Fux, Christoph A; Bianchetti, Mario G; Jakob, Stephan M; Remonda, Luca (2006). Reversible encephalopathy complicating post-streptococcal glomerulonephritis. Pediatric infectious disease journal, 25(1), pp. 85-7. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.imf.0000195614.66987.2f

Tevaearai, Hendrik T; Schmidli, Juerg; Mohacsi, Paul; Rothen, Hans-Ulrich; Eckstein, Friedrich S; Carrel, Thierry P (2006). Leakage of the arterial prosthesis of an Impella RVAD. Annals of thoracic surgery, 82(4), pp. 1527-9. New York, N.Y.: Elsevier 10.1016/j.athoracsur.2006.02.017

Krejci, Vladimir; Hiltebrand, Luzius; Büchi, Conradin; Ali, Syed Z; Contaldo, Claudio; Takala, Jukka; Sigurdsson, Gisli H; Jakob, Stephan M (2006). Decreasing gut wall glucose as an early marker of impaired intestinal perfusion. Critical care medicine, 34(9), pp. 2406-14. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/01.CCM.0000233855.34344.29

Luginbühl, M; Rüfenacht, M; Korhonen, I; Gils, M; Jakob, S; Petersen-Felix, S. (2006). Stimulation induced variability of pulse plethysmography does not discriminate responsiveness to intubation. British journal of anaesthesia, 96(3), pp. 323-329. Oxford: Oxford University Press 10.1093/bja/aei315

Knuesel, Rafael; Takala, Jukka; Brander, Lukas; Haenggi, Matthias; Bracht, Hendrik; Porta, Francesca; Jakob, Stephan M (2006). Membrane microdialysis: Evaluation of a new method to assess splanchnic tissue metabolism. Critical care medicine, 34(10), pp. 2638-45. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/01.CCM.0000239430.73826.23

Brander, Lukas; Jakob, Stephan M; Knuesel, Rafael; Savolainen, Hannu; Widmer, Matthias K; Schmidli, Juerg; Takala, Jukka (2006). Effects of low abdominal blood flow and dobutamine on blood flow distribution and on the hepatic arterial buffer response in anaesthetized pigs. Shock, 25(4), pp. 402-13. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.0000217813.50104.5d

Brander, Lukas; Takala, Jukka (2006). Tracheal tear and tension pneumothorax complicating bronchoscopy-guided percutaneous tracheostomy. Heart & lung, 35(2), pp. 144-5. New York, N.Y.: Elsevier 10.1016/j.hrtlng.2005.09.007

Daudel, Fritz; Bone, Hans-Georg; Traber, Daniel L; Stubbe, Henning D; Lettau, Martin; Lange, Matthias; Scharte, Marion; Van Aken, Hugo; Westphal, Martin (2006). Effects of thoracic epidural anesthesia on hemodynamics and global oxygen transport in ovine endotoxemia. Shock, 26(6), pp. 615-9. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.shk.0000228799.25797.fb

Dünser, Martin W; Hasibeder, Walter R; Wenzel, Volker; Meier-Hellmann, Andreas (2006). [Arginine-vasopressin in septic and vasodilatorial shock]. Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie, 41(11), pp. 716-9. Stuttgart: Thieme 10.1055/s-2006-958842

Dünser, Martin W; Hasibeder, Walter R (2006). Vasopressin in vasodilatory shock: ensure organ blood flow, but take care of the heart! Critical care, 10(6), p. 172. London: BioMed Central 10.1186/cc5089

Ganter, CG; Jakob, SM; Takala, J (2006). Pulmonary capillary pressure. A review. Minerva anestesiologica, 72(1-2), pp. 21-36. Torino: Minerva Medica

Haenggi, Matthias; Ypparila, Heidi; Hauser, Kathrin; Caviezel, Claudio; Korhonen, Ilkka; Takala, Jukka; Jakob, Stephan M (2006). The effects of dexmedetomidine/remifentanil and midazolam/remifentanil on auditory-evoked potentials and electroencephalogram at light-to-moderate sedation levels in healthy subjects. Anesthesia and analgesia, 103(5), pp. 1163-9. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/01.ane.0000237394.21087.85

Porta, Francesca; Takala, Jukka; Weikert, Christian; Kaufmann, Priska; Krahenbuhl, Stephan; Jakob, Stephan M (2006). Effect of endotoxin, dobutamine and dopamine on muscle mitochondrial respiration in vitro. Journal of endotoxin research, 12(6), pp. 358-66. London: Sage 10.1179/096805106X153952

Takala, Jukka (2006). The pulmonary artery catheter: the tool versus treatments based on the tool. Critical care, 10(4), p. 162. London: BioMed Central 10.1186/cc5021

Collaborative Study Group on Perioperative ScvO2 Monitoring (KIM, H; Haenggi, M; Jakob, SM; Loher, S; Raeber, C; Takala, J) (2006). Multicentre study on peri- and postoperative central venous oxygen saturation in high-risk surgical patients. Critical care, 10(6), R158. London: BioMed Central 10.1186/cc5094

Nunes, S; Valta, P; Takala, J (2006). Changes in respiratory mechanics and gas exchange during the acute respiratory distress syndrome. Acta anaesthesiologica Scandinavica, 50(1), pp. 80-91. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2005.00767.x

Mayr, Viktoria D; Dünser, Martin W; Greil, Veronika; Jochberger, Stefan; Luckner, Günter; Ulmer, Hanno; Friesenecker, Barbara E; Takala, Jukka; Hasibeder, Walter R (2006). Causes of death and determinants of outcome in critically ill patients. Critical care, 10(6), R154. London: BioMed Central 10.1186/cc5086

Parviainen, I; Jakob, SM; Suistomaa, M; Takala, J; The, Scandinavian Society of Anaesthesiology; Intensive, Care Medicine (SSAI) (2006). Practical sources of error in measuring pulmonary artery occlusion pressure: a study in participants of a special intensivist training program of The Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI). Acta anaesthesiologica Scandinavica, 50(5), pp. 600-3. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2006.01008.x

Braun, Jan-Peter; Jakob, Stephan M; Volk, Thomas; Doepfmer, Ulrich R; Moshirzadeh, Maryam; Stegmann, Shirin; Dohmen, Pascal M; Spies, Claudia (2006). Arterio-venous gradients of free energy change for assessment of systemic and splanchnic perfusion in cardiac surgery patients. Perfusion, 21(6), pp. 353-60. London: Sage 10.1177/0267659106074004

Friesenecker, Barbara; Tsai, A G; Dünser, M W; Martini, J; Hasibeder, W; Intaglietta, M (2006). Lowered microvascular vessel wall oxygen consumption augments tissue pO2 during PgE1-induced vasodilation. European journal of applied physiology, 99(4), pp. 405-14. Heidelberg: Springer 10.1007/s00421-006-0360-0

Jochberger, Stefan; Morgenthaler, Nils G; Mayr, Viktoria D; Luckner, Günter; Wenzel, Volker; Ulmer, Hanno; Schwarz, Siegfried; Hasibeder, Walter R; Friesenecker, Barbara E; Dünser, Martin W (2006). Copeptin and arginine vasopressin concentrations in critically ill patients. Journal of clinical endocrinology and metabolism, 91(11), pp. 4381-6. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2005-2830

Knotzer, H; Pajk, W; Maier, S; Dünser, M W; Ulmer, H; Schwarz, B; Salak, N; Hasibeder, W R (2006). Comparison of lactated Ringer's, gelatine and blood resuscitation on intestinal oxygen supply and mucosal tissue oxygen tension in haemorrhagic shock. British journal of anaesthesia, 97(4), pp. 509-16. Oxford: Oxford University Press 10.1093/bja/ael208

Friesenecker, Barbara E; Tsai, Amy G; Martini, Judith; Ulmer, Hanno; Wenzel, Volker; Hasibeder, Walter R; Intaglietta, Marcos; Dünser, Martin W (2006). Arteriolar vasoconstrictive response: comparing the effects of arginine vasopressin and norepinephrine. Critical care, 10(3), R75. London: BioMed Central 10.1186/cc4922

Pachl, J; Svoboda, P; Jacobs, F; Vandewoude, K; van der Hoven, B; Spronk, P; Masterson, G; Malbrain, M; Aoun, M; Garbino, J; Takala, J; Drgona, L; Burnie, J; Matthews, R; Mycograb, Invasive Candidiasis Study Group (2006). A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis. Clinical infectious diseases, 42(10), pp. 1404-13. Cary, N.C.: The University of Chicago Press 10.1086/503428

Rasche, F M; Keller, F; Lepper, P M; Aymanns, C; Karges, W; Sailer, L-C; Müller, L von; Czock, D (2006). High-dose intravenous immunoglobulin pulse therapy in patients with progressive immunoglobulin A nephropathy: a long-term follow-up. Clinical and experimental immunology, 146(1), pp. 47-53. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2249.2006.03189.x

Schumann, Christian; Triantafilou, Kathy; Krueger, Stefan; Hombach, Vinzenz; Triantafilou, Martha; Becher, Gunther; Lepper, Philipp M. (2006). Detection of erythropoietin in exhaled breath condensate of nonhypoxic subjects using a multiplex bead array. Mediators of inflammation, 2006(5), p. 18061. Sylvania, Ohio: Hindawi Publishing Corp. 10.1155/MI/2006/18061

Wettstein, Daniela; Moens, Yves; Jaeggin-Schmucker, Nicola; Böhm, Stephan H; Rothen, Hans Ulrich; Mosing, Martina; Kästner, Sabine B R; Schatzmann, Urs (2006). Effects of an alveolar recruitment maneuver on cardiovascular and respiratory parameters during total intravenous anesthesia in ponies. American journal of veterinary research, 67(1), pp. 152-9. Chicago, Ill.: American Veterinary Medical Association 10.2460/ajvr.67.1.152

Dünser, Martin W; Lindner, Karl H; Wenzel, Volker (2006). A century of arginine vasopressin research leading to new therapeutic strategies. Anesthesiology, 105(3), pp. 444-5. Hagerstown, Md.: Lippincott Williams & Wilkins

Hasibeder, Walter; Knotzer, Hans; Friesenecker, Barbara; Dünser, Martin (2006). Comment on "Sublingual capnometry tracks microcirculatory changes in septic patients" by Creteur et al. Intensive care medicine, 32(10), 1665-6; author reply 1667. Berlin: Springer 10.1007/s00134-006-0342-z

Merz, Tobias M; Regli, Bruno; Rothen, Hans-Ulrich; Felleiter, Peter (2006). Propofol infusion syndrome--a fatal case at a low infusion rate. Anesthesia and analgesia, 103(4), p. 1050. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/01.ane.0000239080.82501.c7

Wurz, Jeannie (2006). 26th International Symposium on Intensive Care and Emergency Medicine, 21-24 March 2006, Brussels, Belgium. Critical care, 10(3), p. 309. London: BioMed Central 10.1186/cc4935

Gorrasi, J; Takala, J; Jakob, S (2006). The vascular bed during critical illness: evaluation in animal models. In: , (ed.) (119-128.). Heidelberg: Springer Verlag

Regli, B; Takala, J (2006). The patient process as the basis for the design of an ICU. In: Fink MP, Suter PM (ed.) (pp. 115-132). Heidelberg: Springer Verlag

Takala, J (2006). Introduction: What is Critical Care Medicine? In: Albert RK, Slutsky A (ed.) CLINICAL CRITICAL CARE MEDICINE (xv-xvi). Mosby

Takala, J (2006). Clinical assessment of the acutely unstable patient. In: Albert RK, Slutsky A (ed.) CLINICAL CRITICAL CARE MEDICINE (pp. 187-198). Mosby

Wurz, J; Takala, J (2006). ICU design of the future: Focus on flexibility. ICU management - the official management and practice journal, 6(4), p. 29. Brussels: Euromedical Communications

Zuidema, Xander; Dünser, Martin W; Wenzel, Volker; Rozendaal, Frans W; de Jager, Cornelis P C (2006). Terlipressin as an adjunct vasopressor in refractory hypotension after tricyclic antidepressant intoxication. Resuscitation, 72(2), pp. 319-23. Shannon: Elsevier Science Ireland 10.1016/j.resuscitation.2006.07.005

Albert, Richard K; Slutsky, Arthur S; Ranieri, Marco; Takala, Jukka; Torres, Antoni (eds.) (2006). Clinical Critical Care Medicine. Philadelphia: Mosby


de Marchi, Stefano F.; Oswald, Philipp; Windecker, Stephan; Meier, Bernhard; Seiler, Christian (2005). Reciprocal relationship between left ventricular filling pressure and the recruitable human coronary collateral circulation. European Heart Journal, 26(6), pp. 558-566. Oxford University Press 10.1093/eurheartj/ehi051

Inderbitzin, Daniel; Muggli, Beat; Ringger, Annette; Beldi, Guido; Gass, Markus; Gloor, Beat; Uehlinger, Dominik; Regli, Bruno; Reichen, Jürg; Candinas, Daniel (2005). Molecular absorbent recirculating system for the treatment of acute liver failure in surgical patients. Journal of gastrointestinal surgery, 9(8), pp. 1155-1162. Springer-Verlag 10.1016/j.gassur.2005.07.026


Knüsel, Rafael Matthias; Jakob, Stephan M.; Brander, Lukas; Bracht, Hendrik; Siegenthaler, Andreas; Takala, Jukka (2003). Changes in regional blood flow and pCO2 gradients during isolated abdominal aortic blood flow reduction. Intensive care medicine, 29(12), pp. 2255-2265. Springer-Verlag 10.1007/s00134-003-1954-1

Röck, Margareta Anna; Jakob, Stephan M.; Böhlen, Thomas; Brander, Lukas; Knuesel, Rafael; Takala, Jukka (2003). Change in stroke volume in response to fluid challenge: assessment using esophageal Doppler. Intensive care medicine, 29(10), pp. 1729-1735. Springer-Verlag 10.1007/s00134-003-1720-4

Nunes, Silvia; Ruokonen, Esko; Takala, Jukka (2003). Pulmonary capillary pressures during the acute respiratory distress syndrome. Intensive care medicine, 29(12), pp. 2174-2179. Springer-Verlag 10.1007/s00134-003-2036-0


Uusaro, A.; Lahtinen, P.; Parviainen, I.; Takala, J. (2000). Gastric mucosal end‐tidal Pco2 difference as a continuous indicator of splanchnic perfusion. British journal of anaesthesia, 85(4), pp. 563-569. Oxford University Press 10.1093/bja/85.4.563


Stricker, Kay; Rothen, Hans Ulrich; Fuhrer, Jürg (1998). Atrial tachyarrhythmia after cardiac surgery. Intensive care medicine, 24(7), pp. 654-662. Springer-Verlag 10.1007/s001340050641


Jakob, S. M.; Rothen, Hans Ulrich (1997). Intensive care 1980–1995: change in patient characteristics, nursing workload and outcome. Intensive care medicine, 23(11), pp. 1165-1170. Springer-Verlag 10.1007/s001340050474

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