Ultrasmall superparamagnetic particles of iron oxide allow for the detection of metastases in normal sized pelvic lymph nodes of patients with bladder and/or prostate cancer

Triantafyllou, Maria; Studer, Urs E.; Birkhäuser, Frédéric D.; Fleischmann, Achim; Bains, Lauren J.; Petralia, Giuseppe; Christe, Andreas; Fröhlich, Johannes M.; Thoeny, Harriet C. (2013). Ultrasmall superparamagnetic particles of iron oxide allow for the detection of metastases in normal sized pelvic lymph nodes of patients with bladder and/or prostate cancer. European journal of cancer, 49(3), pp. 616-624. Amsterdam: Elsevier 10.1016/j.ejca.2012.09.034

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Lymph node metastases influence prognosis and outcome in patients with bladder and prostate cancer. Cross sectional imaging criteria are limited in detecting metastases in normal sized lymph nodes. This prospective study assessed the diagnostic accuracy of ultrasmall superparamagnetic particles of iron oxide (USPIO)-enhanced magnetic resonance imaging (MRI) for the detection of metastases in normal sized lymph nodes using extended pelvic lymph node dissection (ePLND) and histopathology as the reference standard.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology
04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Triantafyllou, Maria; Studer, Urs; Birkhäuser, Frédéric; Fleischmann, Achim; Bains, Lauren; Christe, Andreas; Fröhlich, Johannes and Thöny, Harriet C.

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0959-8049

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:33

Last Modified:

26 Nov 2015 12:05

Publisher DOI:

10.1016/j.ejca.2012.09.034

PubMed ID:

23084842

Uncontrolled Keywords:

Bladder cancer, Prostate cancer, Lymph nodes, Metastases, MRI, USPIO, Surgery, Histopathology

BORIS DOI:

10.7892/boris.12955

URI:

https://boris.unibe.ch/id/eprint/12955 (FactScience: 219449)

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