Therapy of retained fetal membranes in cattle: Comparison of two treatment protocols.

Imhof, Stefanie; Luternauer, Michael; Hüsler, Jürg; Steiner, Adrian; Hirsbrunner, Gabriela (2019). Therapy of retained fetal membranes in cattle: Comparison of two treatment protocols. Animal reproduction science, 206, pp. 11-16. Elsevier 10.1016/j.anireprosci.2019.04.013

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This prospective study was conducted to compare two treatment protocols for retained foetal membranes (RFM) in cattle. The routine therapy consisting of intrauterine tetracycline boluses was compared with the administration of ozone foam, both intrauterine therapies without attempts to manually remove the placenta. Cows undergoing caesarean section, suffering from uterine torsion or prolapse of the uterus, and other illnesses than RFM on the first day post-partum were excluded. Values for baseline variables as age, breed, yearly milk yield, parity, pregnancy duration, calving season and number of routine intrauterine treatments were not different between the groups. Number of days with rectal temperature >39.7 °C within the first 10 days in milk (DIM) were greater in the ozone group. Number of escape therapies were recorded when there was imposing of this therapy as a result of cows having a fever (based on rectal temperature >39.7 °C) and a significant reduced food intake. Escape therapies consisted of parenteral administration of tetracyclines and NSAIDS during the first 10 DIM. Number of escape therapies, however, was not different between the groups. Results from use of a logistic regression model with fever as a dichotomous variable indicated there was no effect of breed, studbook, type of stall, pasture, business and no effect of age or milk yield. In a second assessment, cows were evaluated until 200 DIM. Results from a survival analysis indicated group (Te/Oz) did not affect rate of culling from the herd.

Item Type:

Journal Article (Original Article)


08 Faculty of Science > Department of Mathematics and Statistics > Institute of Mathematical Statistics and Actuarial Science
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Clinic for Ruminants

UniBE Contributor:

Hüsler, Rudolf Jürg, Steiner, Adrian, Hirsbrunner, Gabriela


300 Social sciences, sociology & anthropology > 360 Social problems & social services
500 Science > 510 Mathematics
500 Science > 590 Animals (Zoology)
600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture








Nathalie Viviane Zollinger

Date Deposited:

05 Aug 2019 10:51

Last Modified:

05 Dec 2022 15:29

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Cattle Ozone Reduction of antibiotics Retained foetal membranes Tetracycline




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