Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial.

Riesterer, Oliver; Frank Ciernik, I; Stahel, Rolf A; Xyrafas, Alexandros; Aebersold, Daniel; Plasswilm, Ludwig; Mahmut Ozsahin, E; Zwahlen, Daniel R; Nackaerts, Kristiaan; Zimmermann, Frank; Sabrina Stark, L; Weder, Walter; Krayenbuehl, Jérôme (2019). Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial. Radiotherapy and oncology, 138, pp. 121-125. Elsevier 10.1016/j.radonc.2019.05.024

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Postoperative radiotherapy after extrapleural pneumonectomy of malignant pleural mesothelioma was investigated in the randomized phase II trial SAKK17/04. The relapse rate within the high and/or low-dose PTV without previous distant failure was 24%, the isolated in-field-relapse rate within the PTVs was 5% and the distant relapse rate outside of the PTVs was 81%. Clinical outcome was mainly determined by distant disease progression outside of the radiation field.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology

UniBE Contributor:

Aebersold, Daniel and Plasswilm, Ludwig

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0167-8140

Publisher:

Elsevier

Language:

English

Submitter:

Beatrice Scheidegger

Date Deposited:

28 Nov 2019 12:34

Last Modified:

28 Nov 2019 12:43

Publisher DOI:

10.1016/j.radonc.2019.05.024

PubMed ID:

31252293

Uncontrolled Keywords:

Extrapleural pneumonectomy Mesothelioma Multimodal therapy Radiation therapy Radiotherapy Trimodal therapy

BORIS DOI:

10.7892/boris.135034

URI:

https://boris.unibe.ch/id/eprint/135034

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