Isopropanol at 60% and at 70% are effective against 'isopropanol-tolerant' Enterococcus faecium.

Gebel, J; Gemein, S; Kampf, G; Pidot, S J; Buetti, N.; Exner, M (2019). Isopropanol at 60% and at 70% are effective against 'isopropanol-tolerant' Enterococcus faecium. The journal of hospital infection, 103(1), e88-e91. Elsevier 10.1016/j.jhin.2019.01.024

[img]
Preview
Text
Buetti N.pdf - Published Version
Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND).

Download (221kB) | Preview

The bactericidal activity of isopropanol was determined against Enterococcus faecium ATCC 6057, ST 796 (isopropanol-tolerant strain) and Enterococcus hirae ATCC 10541 (EN 13727). Isopropanol at 60% and 70% were effective (≥5.38 log10-reduction) in 15 s against all strains but 23% isopropanol was not (<0.99 log10-reduction in ≤15 min). Isopropanol at 70% was tested against E. faecium in the four-field test. Eight millilitres was not effective enough in 1 min (<5 log10-reduction), whilst 16 mL was effective (≥5.85 log10-reduction). Healthcare workers can be reassured that 60% and 70% isopropanol with an appropriate volume are effective against E. faecium.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology

UniBE Contributor:

Buetti, Niccolò Ivo Marco-Aurelio

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1532-2939

Publisher:

Elsevier

Language:

English

Submitter:

Annelies Luginbühl

Date Deposited:

14 Jan 2020 09:24

Last Modified:

13 Mar 2021 11:34

Publisher DOI:

10.1016/j.jhin.2019.01.024

PubMed ID:

30711531

Uncontrolled Keywords:

Bactericidal activity E. faecium Four-field test Isopropanol ST 796 Tolerance

BORIS DOI:

10.7892/boris.137191

URI:

https://boris.unibe.ch/id/eprint/137191

Actions (login required)

Edit item Edit item
Provide Feedback