Gebel, J; Gemein, S; Kampf, G; Pidot, S J; Buetti, N.; Exner, M (2019). Isopropanol at 60% and at 70% are effective against 'isopropanol-tolerant' Enterococcus faecium. The journal of hospital infection, 103(1), e88-e91. Elsevier 10.1016/j.jhin.2019.01.024
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The bactericidal activity of isopropanol was determined against Enterococcus faecium ATCC 6057, ST 796 (isopropanol-tolerant strain) and Enterococcus hirae ATCC 10541 (EN 13727). Isopropanol at 60% and 70% were effective (≥5.38 log10-reduction) in 15 s against all strains but 23% isopropanol was not (<0.99 log10-reduction in ≤15 min). Isopropanol at 70% was tested against E. faecium in the four-field test. Eight millilitres was not effective enough in 1 min (<5 log10-reduction), whilst 16 mL was effective (≥5.85 log10-reduction). Healthcare workers can be reassured that 60% and 70% isopropanol with an appropriate volume are effective against E. faecium.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology |
UniBE Contributor: |
Buetti, Niccolò Ivo Marco-Aurelio |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1532-2939 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Annelies Luginbühl |
Date Deposited: |
14 Jan 2020 09:24 |
Last Modified: |
05 Dec 2022 15:34 |
Publisher DOI: |
10.1016/j.jhin.2019.01.024 |
PubMed ID: |
30711531 |
Uncontrolled Keywords: |
Bactericidal activity E. faecium Four-field test Isopropanol ST 796 Tolerance |
BORIS DOI: |
10.7892/boris.137191 |
URI: |
https://boris.unibe.ch/id/eprint/137191 |
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