Recurrent Fever and Failure to Thrive in an 11-Year-Old Boy.

Stickel, Felix; Wartenberg, Martin; Bouzourene, Hanifa; Ortner, Maria Anna; Rogler, Gerhard (2019). Recurrent Fever and Failure to Thrive in an 11-Year-Old Boy. Case reports in gastroenterology, 13(2), pp. 350-356. Karger 10.1159/000502604

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Recurrent fever is frequent among children and mostly associated with viral infections inoculated via social contacts with others of the same age. Rarely, severe conditions such as hematological malignancies, pediatric rheumatoid diseases, chronic infections, or inherited recurrent fever syndromes are causative. Herein, we present the case of an 11-year-old boy with frequently recurring high-fever episodes since early childhood, failure to thrive, and iron deficiency who was found to have classical celiac disease (CD) with highly elevated tissue transglutaminase and anti-gliadin antibodies and marked duodenal villous atrophy. Upon implementation of a gluten-free diet, the boy ceased to have fevers, antibodies decreased markedly, his iron status improved, and he significantly gained weight. Although infrequent, recurrent fever should be included into the polymorphic clinical picture of CD, and the threshold of testing for diagnostic antibodies should be low in such patients.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Wartenberg, Martin

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

1662-0631

Publisher:

Karger

Language:

English

Submitter:

Martin Wartenberg

Date Deposited:

28 Jan 2020 09:53

Last Modified:

28 Jan 2020 09:53

Publisher DOI:

10.1159/000502604

PubMed ID:

31607835

Uncontrolled Keywords:

Anemia Autoimmune disease Celiac disease Growth retardation Iron deficiency Zonulin

BORIS DOI:

10.7892/boris.138565

URI:

https://boris.unibe.ch/id/eprint/138565

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