Early and delayed neurological manifestations of cardiac myxomas.

Panos, Leonidas; Brunel, Christophe; Berezowska, Sabina; Engisch, Renate; Kollár, Attila; Bassetti, Claudio; Sturzenegger, Mathias; Krestel, Heinz Eric (2020). Early and delayed neurological manifestations of cardiac myxomas. Clinical neurology and neurosurgery, 190(105673), p. 105673. Elsevier 10.1016/j.clineuro.2020.105673

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Cardiac myxoma can embolize and cause early and delayed sequelae including stroke, growth into intracranial fusiform aneurysms and cerebral tumors with risk of hemorrhage and mass effect. Here, we report the rare coincidence of all these manifestations in a 63-year-old man who presented with cognitive and behavioral changes, and seizures 9 months after an embolic stroke from the heart tumor. C-reactive protein (CRP) was elevated at the time of stroke and cardiac myxoma diagnosis but was normal at late neurologic manifestation with isolated myxoma-related intracranial tumors and aneurysms. Low-dose whole-brain radiotherapy can be helpful to diminish cerebral myxoma tumors and fusiform aneurysms despite reported increased risk of aneurysm rupture.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
04 Faculty of Medicine > Service Sector > Institute of Pathology
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology

UniBE Contributor:

Panos, Leonidas; Berezowska, Sabina Anna; Engisch, Renate; Kollár, Attila; Bassetti, Claudio and Krestel, Heinz Eric

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

0303-8467

Publisher:

Elsevier

Language:

English

Submitter:

Rebeka Gerber

Date Deposited:

27 Apr 2020 09:20

Last Modified:

03 May 2020 02:41

Publisher DOI:

10.1016/j.clineuro.2020.105673

PubMed ID:

31945622

Uncontrolled Keywords:

CRP Fusiform aneurysm Myxoma Radiotherapy Stellate cells

BORIS DOI:

10.7892/boris.143125

URI:

https://boris.unibe.ch/id/eprint/143125

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