Dysbiosis is not present in horses with fecal water syndrome when compared to controls in spring and autumn.

Schoster, Angelika; Weese, J. Scott; Gerber, Vinzenz; Graubner, Claudia Nicole (2020). Dysbiosis is not present in horses with fecal water syndrome when compared to controls in spring and autumn. Journal of veterinary internal medicine, 34(4), pp. 1614-1621. Wiley-Blackwell 10.1111/jvim.15778

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BACKGROUND

Fecal water syndrome (FWS) is long-standing and common in horses, particularly in central Europe. No large epidemiological data sets exist, and the cause remains elusive. Dysbiosis could play a role in pathogenesis.

OBJECTIVES

To evaluate whether dysbiosis is present in horses with FWS when compared to stable-matched control horses in spring and autumn.

ANIMALS

Fecal samples were collected from horses with FWS (n = 16; 9 mares, 7 geldings) and controls (n = 15; 8 mares, 7 geldings).

METHODS

The bacterial microbiome of samples collected in spring and autumn of 2016 was analyzed using high-throughput sequencing. Differences in relative abundance of bacterial taxa, alpha diversity, and beta diversity indices were assessed between horses with FWS and controls based on season.

RESULTS

Differences in microbial community composition based on time point and health status were not observed on any taxonomic level. Limited differences were seen on linear discriminant analysis effect size analysis. No difference in alpha diversity indices was observed including richness, diversity based on health status, or time point. No effect of health status on microbial community membership structure was observed.

CONCLUSIONS AND CLINICAL IMPORTANCE

Limited differences were found in the bacterial microbiota of horses with and without FWS, regardless of season. Further research is needed to elucidate the role of microbiota in the development of FWS.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Equine Clinic
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)

UniBE Contributor:

Gerber, Vinzenz and Graubner, Claudia

Subjects:

600 Technology > 630 Agriculture

ISSN:

0891-6640

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Ursula Therese Horst

Date Deposited:

30 Jul 2020 09:53

Last Modified:

28 Apr 2021 11:40

Publisher DOI:

10.1111/jvim.15778

PubMed ID:

32588473

Uncontrolled Keywords:

clostridiales fecal water syndrome gastrointestinal microbiota horse metagenomic sequencing

BORIS DOI:

10.7892/boris.145461

URI:

https://boris.unibe.ch/id/eprint/145461

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