VOR gain calculation methods in video head impulse recordings.

Zamaro, Ewa; Tehrani, Ali S; Kattah, Jorge C; Eibenberger, Karin; Guede, Cynthia I; Lenz, Armando; Caversaccio, Marco D.; Newman-Toker, David E; Mantokoudis, Georgios (2020). VOR gain calculation methods in video head impulse recordings. Journal of vestibular research - equilibrium & orientation, 30(4), pp. 225-234. IOS Press 10.3233/VES-200708

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BACKGROUND

International consensus on best practices for calculating and reporting vestibular function is lacking. Quantitative vestibulo-ocular reflex (VOR) gain using a video head impulse test (HIT) device can be calculated by various methods.

OBJECTIVE

To compare different gain calculation methods and to analyze interactions between artifacts and calculation methods.

METHODS

We analyzed 1300 horizontal HIT traces from 26 patients with acute vestibular syndrome and calculated the ratio between eye and head velocity at specific time points (40 ms, 60 ms) after HIT onset ('velocity gain'), ratio of velocity slopes ('regression gain'), and ratio of area under the curves after de-saccading ('position gain').

RESULTS

There was no mean difference between gain at 60 ms and position gain, both showing a significant correlation (r2 = 0.77, p < 0.001) for artifact-free recordings. All artifacts reduced high, normal-range gains modestly (range - 0.06 to - 0.11). The impact on abnormal, low gains was variable (depending on the artifact type) compared to artifact-free recordings.

CONCLUSIONS

There is no clear superiority of a single gain calculation method for video HIT testing. Artifacts cause small but significant reductions of measured VOR gains in HITs with higher, normal-range gains, regardless of calculation method. Artifacts in abnormal HITs with low gain increased measurement noise. A larger number of HITs should be performed to confirm abnormal results, regardless of calculation method.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > CTU Bern
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)

UniBE Contributor:

Zamaro, Ewa; Lenz, Armando; Caversaccio, Marco and Mantokoudis, Georgios

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0957-4271

Publisher:

IOS Press

Funders:

[4] Swiss National Science Foundation

Language:

English

Submitter:

Andrea Flükiger-Flückiger

Date Deposited:

28 Aug 2020 09:42

Last Modified:

23 Nov 2020 07:34

Publisher DOI:

10.3233/VES-200708

PubMed ID:

32804110

Uncontrolled Keywords:

HIT device VOR area under the curve artifacts calculation methods gain position gain regression regression gain vHIT video head impulse test video-oculography

BORIS DOI:

10.7892/boris.146118

URI:

https://boris.unibe.ch/id/eprint/146118

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